Patents by Inventor Shinya Kurata

Shinya Kurata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11935944
    Abstract: The on-state characteristics of a transistor are improved and thus, a semiconductor device capable of high-speed response and high-speed operation is provided. A highly reliable semiconductor device showing stable electric characteristics is made. The semiconductor device includes a transistor including a first oxide layer; an oxide semiconductor layer over the first oxide layer; a source electrode layer and a drain electrode layer in contact with the oxide semiconductor layer; a second oxide layer over the oxide semiconductor layer; a gate insulating layer over the second oxide layer; and a gate electrode layer over the gate insulating layer. An end portion of the second oxide layer and an end portion of the gate insulating layer overlap with the source electrode layer and the drain electrode layer.
    Type: Grant
    Filed: September 2, 2022
    Date of Patent: March 19, 2024
    Assignee: Semiconductor Energy Laboratory Co., Ltd.
    Inventors: Shunpei Yamazaki, Hideomi Suzawa, Shinya Sasagawa, Motomu Kurata, Masashi Tsubuku
  • Publication number: 20180087096
    Abstract: Provided are techniques by which a mutant gene in a gene group comprising a large number of wild-type genes can be detected with high sensitivity and in a rapid and simple way. Provided is a method for measuring a nucleic acid for the purpose of specifically detecting a genotype as an examination target from subjects which are genes or specimens likely to have a plurality of genetic polymorphisms, wherein the measurement method comprises hybridizing a fluorescent dye-labeled oligonucleotide with a genotype other than the examination target to suppress the gene amplification of such genotype while at the same time, hybridizing the same fluorescence-labeled oligo as described above with an amplification product derived from the genotype of the examination target amplified in the same gene amplification step as described above, and specifically detecting the genotype of the examination target based on a change in the fluorescence intensity of the fluorescent dye before and after the hybridization.
    Type: Application
    Filed: March 29, 2016
    Publication date: March 29, 2018
    Applicant: NIPPON STEEL & SUMIKIN ECO-TECH CORPORATION
    Inventors: Masahiro YAMAGUCHI, Shinya KURATA, Norio KOMATSU, Soji MORISHITA
  • Patent number: 9587271
    Abstract: [Problems] To provide a novel mixture for assaying a target nucleic acid, characterized by enabling a nucleic acid assay while: 1) requiring no step of diluting the target nucleic acid; 2) requiring no procedure of changing a probe concentration depending on a concentration of the target nucleic acid. [Means for Solving Problems] 1) A mixture which comprises one internal standard nucleic acid and two nucleic acid probes labeled with a fluorescent dye; 2) a mixture for measuring Km value which comprises one internal standard nucleic acid having a partial mutation and one nucleic acid probe labeled with a fluorescent dye; 3) a mixture which comprises one internal standard nucleic acid and one double nucleic acid probe labeled with two fluorescent dyes; and a method for assaying a nucleic acid by making use thereof.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: March 7, 2017
    Assignee: NIPPON STEEL & SUMIKIN ECO-TECH CORPORATION
    Inventors: Kazunori Nakamura, Takahiro Kanagawa, Naohiro Noda, Satoshi Tsuneda, Hidenori Tani, Shinya Kurata
  • Publication number: 20150368712
    Abstract: A nucleic acid probe set includes (A) a fluorescent probe and (B) a binding probe. The fluorescent probe (A) is formed of an oligonucleotide, which includes (a) a nucleotide unit labeled with (d) a fluorescent substance. The binding probe (B) is formed of an oligonucleotide having (b1) a fluorescent probe binding region, which can hybridize to the fluorescent probe (A), and (b2) a target nucleic acid binding region, which can hybridize to a target nucleic acid sequence (C). The fluorescent substance (d) is a fluorescent substance which changes in fluorescent character upon interaction with guanine. At least one of nucleotide units which constitute the fluorescent probe (A) is an artificial nucleotide unit having a function to raise a dissociation temperature between the probe (A) and the fluorescent probe binding region (b1). The nucleic acid probe is provided with an improved fluorescence quenching efficiency.
    Type: Application
    Filed: September 8, 2015
    Publication date: December 24, 2015
    Inventors: Yuji SEKIGUCHI, Naohiro NODA, Ryo MIYATA, Kazunori NAKAMURA, Shinya KURATA, Satoshi TSUNEDA, Hidenori TANI
  • Publication number: 20140248611
    Abstract: Objects are to provide nucleic acid probes, which in the detection of target nucleic acids with fluorescent quenching probes, can assay a greater variety of target nucleic acids at the same time while suppressing increases in assay labor and cost, and also a method for assaying target nucleic acids by using the nucleic acid probes. Provided is a nucleic acid probe having a base sequence hybridizable with a target nucleic acid sequence in a target nucleic acid.
    Type: Application
    Filed: June 18, 2012
    Publication date: September 4, 2014
    Applicant: NIPPON STEEL & SUMIKIN ECO-TECH CORPORATION
    Inventors: Kohei Ichikawa, Akiyoshi Hanawa, Shinya Kurata
  • Publication number: 20140178876
    Abstract: A nucleic acid probe set includes (A) a fluorescent probe and (B) a binding probe. The fluorescent probe (A) is formed of an oligonucleotide, which includes (a) a nucleotide unit labeled with (d) a fluorescent substance. The binding probe (B) is formed of an oligonucleotide having (b1) a fluorescent probe binding region, which can hybridize to the fluorescent probe (A), and (b2) a target nucleic acid binding region, which can hybridize to a target nucleic acid sequence (C). The fluorescent substance (d) is a fluorescent substance which changes in fluorescent character upon interaction with guanine. At least one of nucleotide units which constitute the fluorescent probe (A) is an artificial nucleotide unit having a function to raise a dissociation temperature between the probe (A) and the fluorescent probe binding region (b1). The nucleic acid probe is provided with an improved fluorescence quenching efficiency.
    Type: Application
    Filed: December 2, 2013
    Publication date: June 26, 2014
    Applicant: Nippon Steel & Sumikin Eco-Tech Corporation
    Inventors: Yuji SEKIGUCHI, Naohiro NODA, Ryo MIYATA, Kazunori NAKAMURA, Shinya KURATA, Satoshi TSUNEDA, Hidenori TANI
  • Publication number: 20130065237
    Abstract: [Problems] To provide a novel mixture for assaying a target nucleic acid, characterized by enabling a nucleic acid assay while: 1) requiring no step of diluting the target nucleic acid; 2) requiring no procedure of changing a probe concentration depending on a concentration of the target nucleic acid. [Means for Solving Problems] 1) A mixture which comprises one internal standard nucleic acid and two nucleic acid probes labeled with a fluorescent dye; 2) a mixture for measuring Km value which comprises one internal standard nucleic acid having a partial mutation and one nucleic acid probe labeled with a fluorescent dye; 3) a mixture which comprises one internal standard nucleic acid and one double nucleic acid probe labeled with two fluorescent dyes; and a method for assaying a nucleic acid by making use thereof.
    Type: Application
    Filed: October 31, 2012
    Publication date: March 14, 2013
    Inventors: Kazunori NAKAMURA, Takahiro Kanagawa, Naohiro Noda, Satoshi Tsuneda, Hidenori Tani, Shinya Kurata
  • Publication number: 20110224417
    Abstract: [Problems] To provide a novel mixture for assaying a target nucleic acid, characterized by enabling a nucleic acid assay while: 1) requiring no step of diluting the target nucleic acid; 2) requiring no procedure of changing a probe concentration depending on a concentration of the target nucleic acid. [Means for Solving Problems] 1) A mixture which comprises one internal standard nucleic acid and two nucleic acid probes labeled with a fluorescent dye; 2) a mixture for measuring Km value which comprises one internal standard nucleic acid having a partial mutation and one nucleic acid probe labeled with a fluorescent dye; 3) a mixture which comprises one internal standard nucleic acid and one double nucleic acid probe labeled with two fluorescent dyes; and a method for assaying a nucleic acid by making use thereof.
    Type: Application
    Filed: April 19, 2011
    Publication date: September 15, 2011
    Applicants: KANKYO ENGINEERING CO., LTD., NATIONAL INSTITUTE OF ADV. INDUSTRIAL SCI. & TECH.
    Inventors: KAZUNORI NAKAMURA, TAKAHIRO KANAGAWA, NAOHIRO NODA, SATOSHI TSUNEDA, HIDENORI TANI, SHINYA KURATA
  • Publication number: 20110212442
    Abstract: A nucleic acid probe set includes (A) a fluorescent probe and (B) a binding probe. The fluorescent probe (A) is formed of an oligonucleotide, which includes (a) a nucleotide unit labeled with (d) a fluorescent substance. The binding probe (B) is formed of an oligonucleotide having (b1) a fluorescent probe binding region, which can hybridize to the fluorescent probe (A), and (b2) a target nucleic acid binding region, which can hybridize to a target nucleic acid sequence (C). The fluorescent substance (d) is a fluorescent substance which changes in fluorescent character upon interaction with guanine. At least one of nucleotide units which constitute the fluorescent probe (A) is an artificial nucleotide unit having a function to raise a dissociation temperature between the probe (A) and the fluorescent probe binding region (b1). The nucleic acid probe is provided with an improved fluorescence quenching efficiency.
    Type: Application
    Filed: July 30, 2009
    Publication date: September 1, 2011
    Applicant: Nippon Steel Kankyo Engineering Co., Ltd.
    Inventors: Yuji Sekiguchi, Naohiro Noda, Ryo Miyata, Kazunori Nakamura, Shinya Kurata, Satoshi Tsuneda, Hidenori Tani
  • Publication number: 20110189666
    Abstract: A nucleic acid probe set includes (A) a fluorescent probe and (B) a binding probe. The fluorescent probe (A) is formed of an oligonucleotide including (a) a nucleotide labeled with a fluorescent substance. The binding probe (B) is formed of an oligonucleotide having (b1) a fluorescent probe binding region, to which the fluorescent probe (A) can hybridize, and (b2) a target nucleic acid binding region, which can hybridize to a target nucleic acid (C). The nucleic acid probe set is designed such that, when the fluorescent probe (A) hybridizes to the fluorescent probe binding region (b1) and the target nucleic acid (C) hybridizes to the target nucleic acid binding region (b2), guanine in the target nucleic acid (C) and the fluorescent substance (d) labeled on the nucleotide (a) interact with each other to change a fluorescent character of the fluorescent substance (d).
    Type: Application
    Filed: July 30, 2008
    Publication date: August 4, 2011
    Applicant: Nippon Steel Kankyo Engineering Co., Ltd
    Inventors: Kohei Ichikawa, Kazunori Nakamura, Shinya Kurata
  • Patent number: 7951604
    Abstract: To provide a novel mixture for assaying a target nucleic acid, characterized by enabling a nucleic acid assay while: 1) requiring no step of diluting the target nucleic acid; 2) requiring no procedure of changing a probe concentration depending on a concentration of the target nucleic acid. 1) A mixture which comprises one internal standard nucleic acid and two nucleic acid probes labeled with a fluorescent dye; 2) a mixture for measuring Km value which comprises one internal standard nucleic acid having a partial mutation and one nucleic acid probe labeled with a fluorescent dye; 3) a mixture which comprises one internal standard nucleic acid and one double nucleic acid probe labeled with two fluorescent dyes; and a method for assaying a nucleic acid by making use thereof.
    Type: Grant
    Filed: August 13, 2009
    Date of Patent: May 31, 2011
    Assignees: Kankyo Engineering Co., Ltd., National Institute of Advanced Industrial Science and Technology
    Inventors: Kazunori Nakamura, Takahiro Kanagawa, Naohiro Noda, Satoshi Tsuneda, Hidenori Tani, Shinya Kurata
  • Patent number: 7785795
    Abstract: A novel method is provided to assay at least one nucleic acid. According to this method, a nucleic acid polymerization reaction is conducted in a nucleic acid polymerization reaction system, which contains (A) the at least one nucleic acid as a template, (B) at least one nucleotide monomer labeled with at least one label selected from the group consisting of (a) fluorescent dyes, (b) quenchers and (c) immune related substances with a fluorescent dye or quencher contained therein, and (C) at least one nucleic acid-synthesizing enzyme. The template nucleic acid or a nucleic acid, which has been synthesized using the template nucleic acid as a template, is then assayed from a change or an amount of a change in an optical character of the nucleic acid polymerization system.
    Type: Grant
    Filed: April 10, 2009
    Date of Patent: August 31, 2010
    Assignees: Kankyo Engineering Co., Ltd., National Institute of Advanced Industrial Science and Technology
    Inventors: Shinya Kurata, Kyoko Takatsu, Kazunori Nakamura, Takahiro Kanagawa
  • Publication number: 20100015719
    Abstract: [Problems] To provide a novel mixture for assaying a target nucleic acid, characterized by enabling a nucleic acid assay while: 1) requiring no step of diluting the target nucleic acid; 2) requiring no procedure of changing a probe concentration depending on a concentration of the target nucleic acid. [Means for Solving Problems] 1) A mixture which comprises one internal standard nucleic acid and two nucleic acid probes labeled with a fluorescent dye; 2) a mixture for measuring Km value which comprises one internal standard nucleic acid having a partial mutation and one nucleic acid probe labeled with a fluorescent dye; 3) a mixture which comprises one internal standard nucleic acid and one double nucleic acid probe labeled with two fluorescent dyes; and a method for assaying a nucleic acid by making use thereof.
    Type: Application
    Filed: August 13, 2009
    Publication date: January 21, 2010
    Applicants: KANKYO ENGINEERING Co., Ltd., National Institute of Adv. Industrial Sci. & Tech.
    Inventors: Kazunori NAKAMURA, Takahiro Kanagawa, Naohiro Noda, Satoshi Tsuneda, Hidenori Tani, Shinya Kurata
  • Publication number: 20090233308
    Abstract: A novel method is provided to assay at least one nucleic acid. According to this method, a nucleic acid polymerization reaction is conducted in a nucleic acid polymerization reaction system, which contains (A) the at least one nucleic acid as a template, (B) at least one nucleotide monomer labeled with at least one label selected from the group consisting of (a) fluorescent dyes, (b) quenchers and (c) immune related substances with a fluorescent dye or quencher contained therein, and (C) at least one nucleic acid-synthesizing enzyme. The template nucleic acid or a nucleic acid, which has been synthesized using the template nucleic acid as a template, is then assayed from a change or an amount of a change in an optical character of the nucleic acid polymerization system.
    Type: Application
    Filed: April 10, 2009
    Publication date: September 17, 2009
    Applicants: KANKYO ENGINEERING Co., Ltd., Nat Institute of Advance Indust Science & Tech.
    Inventors: Shinya KURATA, Kyoko Takatsu, Kazunori Nakamura, Takahiro Kanagawa
  • Patent number: 7429655
    Abstract: A method is provided for determining a concentration of a target nucleic acid by using a nucleic acid probe labeled with a fluorescent dye. The method comprises: providing, as the probe, a nucleic acid probe capable of reducing fluorescence emission from the fluorescent dye when hybridized with the target nucleic acid; hybridizing the probe to the target nucleic acid; and measuring a decrease in fluorescence emission from the fluorescent dye after the hybridization relative to fluorescence emission from the fluorescent dye before the hybridization.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: September 30, 2008
    Assignees: Kankyo Engineering Co., Ltd., National Institute of Advanced Industrial Science and Technology
    Inventors: Ryuichiro Kurane, Takahiro Kanagawa, Yoichi Kamagata, Shinya Kurata, Kazutaka Yamada, Toyokazu Yokomaku, Osamu Koyama, Kenta Furusho
  • Patent number: 7419786
    Abstract: A method is provided for determining a concentration of a target nucleic acid by using a nucleic acid probe labeled with a fluorescent dye. The method comprises: providing, as the probe, a nucleic acid probe capable of reducing fluorescence emission from the fluorescent dye when hybridized with the target nucleic acid; hybridizing the probe to the target nucleic acid; and measuring a decrease in fluorescence emission from the fluorescent dye after the hybridization relative to fluorescence emission from the fluorescent dye before the hybridization.
    Type: Grant
    Filed: January 27, 2006
    Date of Patent: September 2, 2008
    Assignees: Japan Bioindustry Association, Japan as represented by Secretary of Agency of Industrial Science and Technology, KANKYO ENGINEERING Co., Ltd.
    Inventors: Ryuichiro Kurane, Takahiro Kanagawa, Yoichi Kamagata, Shinya Kurata, Kazutaka Yamada, Toyokazu Yokomaku, Osamu Koyama, Kenta Furusho
  • Patent number: 7354707
    Abstract: Nucleic acid probes are provided, each of which is formed of a single-stranded oligonucleotide which can hybridize to a target nucleic acid and is labeled with a fluorescent dye or with a fluorescent dye and a quencher substance. The nucleic acid probes can be easily designed, permit determination, polymorphous analysis or real-time quantitative PCR of nucleic acids in short time, and are not dissociated during reactions. Nucleic acid determination methods, polymorphous analysis methods and real-time quantitative PCR methods, which make use of the nucleic acid probes, are also provided.
    Type: Grant
    Filed: June 27, 2001
    Date of Patent: April 8, 2008
    Assignees: National Institute of Advanced Industrial Science and Technology, Kankyo Engineering Co., Ltd.
    Inventors: Ryuichiro Kurane, Takahiro Kanagawa, Yoichi Kamagata, Masaki Torimura, Shinya Kurata, Kazutaka Yamada, Toyokazu Yokomaku
  • Patent number: 7273700
    Abstract: A novel nucleic acid probe for nucleic acid determination includes a single-stranded nucleic acid labeled with plural fluorescent dyes containing at least one pair of fluorescent dyes to induce FRET, the pair of fluorescent dyes including a fluorescent dye (a donor dye) capable of serving as a donor dye and a fluorescent dye (an acceptor dye) capable of serving as an acceptor dye, in which the nucleic acid probe has such a base sequence and is labeled with the fluorescent dyes so that the fluorescence intensity of the acceptor dye decreases upon hybridization with a target nucleic acid. A novel nucleic acid determination method uses the probe. The probe and method can determine one or more types of target nucleic acids in an assay system in parallel using a simple apparatus.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: September 25, 2007
    Assignees: National Institute of Advanced Industrial Science and Technology, Kankyo Engineering Co., Ltd.
    Inventors: Ryuichiro Kurane, Takahiro Kanagawa, Yoichi Kamagata, Masaki Torimura, Shinya Kurata, Kazutaka Yamada, Toyokazu Yokomaku
  • Publication number: 20070128608
    Abstract: [Problems] To provide a novel mixture for assaying a target nucleic acid, characterized by enabling a nucleic acid assay while: 1) requiring no step of diluting the target nucleic acid; 2) requiring no procedure of changing a probe concentration depending on a concentration of the target nucleic acid. [Means for Solving Problems] 1) A mixture which comprises one internal standard nucleic acid and two nucleic acid probes labeled with a fluorescent dye; 2) a mixture for measuring Km value which comprises one internal standard nucleic acid having a partial mutation and one nucleic acid probe labeled with a fluorescent dye; 3) a mixture which comprises one internal standard nucleic acid and one double nucleic acid probe labeled with two fluorescent dyes; and a method for assaying a nucleic acid by making use thereof.
    Type: Application
    Filed: December 20, 2004
    Publication date: June 7, 2007
    Applicants: Kankyo Engineering Co., Ltd., National Institute of Adv. Industrial Sci. & Tech.
    Inventors: Kazunori Nakamura, Takahiro Kanagawa, Naohiro Noda, Satoshi Tsuneda, Hidenori Tani, Shinya Kurata
  • Patent number: 7094540
    Abstract: A method is provided for determining a concentration of a target nucleic acid by using a nucleic acid probe labeled with a fluorescent dye. The method comprises: providing, as the probe, a nucleic acid probe capable of reducing fluorescence emission from the fluorescent dye when hybridized with the target nucleic acid; hybridizing the probe to the target nucleic acid; and measuring a decrease in fluorescence emission from the fluorescent dye after the hybridization relative to fluorescence emission from the fluorescent dye before the hybridization.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: August 22, 2006
    Assignees: Japan Bioindustry Association, Agency of Industrial Science and Technology, Kankyo Engineering Co., Ltd.
    Inventors: Ryuichiro Kurane, Takahiro Kanagawa, Yoichi Kamagata, Shinya Kurata, Kazutaka Yamada, Toyokazu Yokomaku, Osamu Koyama, Kenta Furusho