Patents by Inventor Shinzo Seko

Shinzo Seko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8304558
    Abstract: Disclosed is a simple and advantageous method for producing a thiazole compound, which method is suitable for commercial-scale implementation. In this method, a thiazole compound is produced by a reaction between 2-halogeno-allylisothiocyanate and sulfuryl chloride generating a large amount of heat, while suppressing decrease in the yield of the thiazole compound. Specifically disclosed is a method for producing 2-chloro-5-chloromethylthiazole represented by the formula (1): This method is characterized in that sulfuryl chloride is added to and reacted with 2-halogeno-allylisothiocyanate represented by the formula (2): wherein Hal represents chlorine or bromine, while blowing a gas inactive to the reaction into the reaction liquid.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: November 6, 2012
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Naoyuki Takano, Morio Yamamoto, Shinzo Seko
  • Patent number: 8269044
    Abstract: Disclosed is a method for producing a primary amine compound represented by the formula (3): wherein, Ar is as defined below, which is characterized in that a halogen compound represented by the formula (1): wherein, Ar represents an unsubstituted aromatic group such as a phenyl group, a naphthyl group, a pyridyl group, a furyl group, a thienyl group, a pyrrolyl group, an oxazolyl group, an isoxazolyl group or a pyrimidinyl group, or an aromatic group obtained by substituting such an unsubstituted aromatic group with 1-3 substituents; and X represents a halogen atom, ammonia and formaldehyde are reacted with each other, thereby obtaining a hexahydrotriazine compound represented by the formula (2): wherein, Ar is as defined above, and then the thus-obtained hexahydrotriazine compound is decomposed. By this method, a primary amine compound can be commercially advantageously produced by using a low-cost ammonia while suppressing production of a secondary amine as a by-product.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: September 18, 2012
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Naoyuki Takano, Kazuyuki Tanaka, Shinzo Seko
  • Patent number: 7977490
    Abstract: A process for producing a thiazole compound of the formula (3): wherein X1 is a hydrogen atom or a halogen atom, which comprises reacting a compound of the formula (1): wherein X1 is as defined above, and X2 represents a halogen atom, with ammonia and formaldehyde to obtain a hexahydrotriazine compound of the formula (2): wherein X1 is as defined above, and reacting the resulting hexahydrotriazine compound with hydroxylamine under acidic conditions. According to this process, the thiazole compound of the formula (3) can be industrially advantageously produced using inexpensive ammonia with suppressing the formation of a byproduct of the formula (4): wherein X1 is as defined above.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: July 12, 2011
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Kazuyuki Tanaka, Naoyuki Takano, Shinzo Seko
  • Publication number: 20110054185
    Abstract: A process for producing a thiazole compound of the formula (3): wherein X1 is a hydrogen atom or a halogen atom, which comprises reacting a compound of the formula (1): wherein X1 is as defined above, and X2 represents a halogen atom, with ammonia and formaldehyde to obtain a hexahydrotriazine compound of the formula (2): wherein X1 is as defined above, and reacting the resulting hexahydrotriazine compound with hydroxylamine under acidic conditions. According to this process, the thiazole compound of the formula (3) can be industrially advantageously produced using inexpensive ammonia with suppressing the formation of a byproduct of the formula (4): wherein X1 is as defined above.
    Type: Application
    Filed: April 5, 2006
    Publication date: March 3, 2011
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Kazuyuki Tanaka, Naoyuki Takano, Shinzo Seko
  • Patent number: 7745669
    Abstract: A process for the production of an alcohol compound represented by the formula (3): wherein X1, X2, X3, X4, Z, R and n are as defined below, comprising reacting a phenol represented by the formula (1): wherein X1, X2, X3 and X4 independently represent a hydrogen atom, a halogen atom or an alkyl group having 1 to 3 carbon atoms; Z represents an oxygen atom or a sulfur atom; and R represents an alkyl group, an alkenyl group, an alkynyl group, or an aralkyl group which may be substituted by a halogen atom, with a haloalcohol represented by the formula (2): wherein Y represents a chlorine atom or a bromine atom; and n represents an integer of 2 or 3, in a biphase system composed of a water-immiscible organic solvent and an aqueous alkali metal hydroxide solution in the presence of a phase-transfer catalyst.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: June 29, 2010
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Toru Sakamoto, Shinzo Seko
  • Publication number: 20100094022
    Abstract: Disclosed is a simple and advantageous method for producing a thiazole compound, which method is suitable for commercial-scale implementation. In this method, a thiazole compound is produced by a reaction between 2-halogeno-allylisothiocyanate and sulfuryl chloride generating a large amount of heat, while suppressing decrease in the yield of the thiazole compound. Specifically disclosed is a method for producing 2-chloro-5-chloromethylthiazole represented by the formula (1): This method is characterized in that sulfuryl chloride is added to and reacted with 2-halogeno-allylisothiocyanate represented by the formula (2): wherein Hal represents chlorine or bromine, while blowing a gas inactive to the reaction into the reaction liquid.
    Type: Application
    Filed: January 11, 2007
    Publication date: April 15, 2010
    Inventors: Naoyuki Takano, Morio Yamamoto, Shinzo Seko
  • Patent number: 7652177
    Abstract: A process for the production of an alcohol compound represented by the formula (3): wherein X1, X2, X3, X4, Z, R and n are as defined below, comprising reacting a phenol represented by the formula (1): wherein X1, X2, X3 and X4 independently represent a hydrogen atom, a halogen atom or an alkyl group having 1 to 3 carbon atoms; Z represents an oxygen atom or a sulfur atom; and R represents a halogen-substituted alkenyl group, with a haloalcohol represented by the formula (2): wherein Y represents a chlorine atom or a bromine atom; and n represents an integer of 2 or 3, in a biphase system composed of a water-immiscible organic solvent and an aqueous alkali metal hydroxide solution in the presence of a phase-transfer catalyst.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: January 26, 2010
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Toru Sakamoto, Shinzo Seko
  • Patent number: 7652170
    Abstract: Disclosed is a method for producing a primary amine compound represented by the formula (2) below, which is characterized in that a halogen compound represented by the formula (1) below, ammonia and formaldehyde are reacted with each other, and then the thus-obtained reaction product is [1] brought into contact with an aqueous solution of an acid or [2] reacted with a hydroxylamine under acidic conditions. By this method, a primary amine compound can be commercially advantageously produced by using a low-cost ammonia while suppressing production of a secondary amine as a by-product. (1) (In the formula, R1 and R2 independently represent a hydrogen atom, a C1-C5 alkyl group which may be substituted by a halogen atom or the like, a C1-C5 alkoxy group which may be substituted by a halogen atom, a cyano group, a C2-C11 alkenyl group or a phenyl group or the like; R3 represents a hydrogen atom, a linear or branched C1-C5 alkyl group or a cyano group; and X represents a halogen atom.
    Type: Grant
    Filed: December 25, 2006
    Date of Patent: January 26, 2010
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Hiroshi Souda, Naoyuki Takano, Shinzo Seko
  • Publication number: 20090287023
    Abstract: Disclosed is a method for producing a primary amine compound represented by the formula (2) below, which is characterized in that a halogen compound represented by the formula (1) below, ammonia and formaldehyde are reacted with each other, and then the thus-obtained reaction product is [1] brought into contact with an aqueous solution of an acid or [2] reacted with a hydroxylamine under acidic conditions. By this method, a primary amine compound can be commercially advantageously produced by using a low-cost ammonia while suppressing production of a secondary amine as a by-product. (1) (In the formula, R1 and R2 independently represent a hydrogen atom, a C1-C5 alkyl group which may be substituted by a halogen atom or the like, a C1-C5 alkoxy group which may be substituted by a halogen atom, a cyano group, a C2-C11 alkenyl group or a phenyl group or the like; R3 represents a hydrogen atom, a linear or branched C1-C5 alkyl group or a cyano group; and X represents a halogen atom.
    Type: Application
    Filed: December 25, 2006
    Publication date: November 19, 2009
    Inventors: Hiroshi Souda, Naoyuki Takano, Shinzo Seko
  • Publication number: 20090281325
    Abstract: Disclosed is a method for producing a primary amine compound represented by the formula (3): wherein, Ar is as defined below , which is characterized in that a halogen compound represented by the formula (1): wherein, Ar represents an unsubstituted aromatic group such as a phenyl group, a naphthyl group, a pyridyl group, a furyl group, a thienyl group, a pyrrolyl group, an oxazolyl group, an isoxazolyl group or a pyrimidinyl group, or an aromatic group obtained by substituting such an unsubstituted aromatic group with 1-3 substituents; and X represents a halogen atom, ammonia and formaldehyde are reacted with each other, thereby obtaining a hexahydrotriazine compound represented by the formula (2): wherein, Ar is as defined above, and then the thus-obtained hexahydrotriazine compound is decomposed. By this method, a primary amine compound can be commercially advantageously produced by using a low-cost ammonia while suppressing production of a secondary amine as a by-product.
    Type: Application
    Filed: December 14, 2006
    Publication date: November 12, 2009
    Inventors: Naoyuki Takano, Kazuyuki Tanaka, Shinzo Seko
  • Publication number: 20090259074
    Abstract: A process for the production of an alcohol compound represented by the formula (3): wherein X1, X2, X3, X4, Z, R and n are as defined below, comprising reacting a phenol represented by the formula (1): wherein X1, X2, X3 and X4 independently represent a hydrogen atom, a halogen atom or an alkyl group having 1 to 3 carbon atoms; Z represents an oxygen atom or a sulfur atom; and R represents an alkyl group, an alkenyl group, an alkynyl group, or an aralkyl group which may be substituted by a halogen atom, with a haloalcohol represented by the formula (2): wherein Y represents a chlorine atom or a bromine atom; and n represents an integer of 2 or 3, in a biphase system composed of a water-immiscible organic solvent and an aqueous alkali metal hydroxide solution in the presence of a phase-transfer catalyst.
    Type: Application
    Filed: July 3, 2007
    Publication date: October 15, 2009
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Toru Sakamoto, Shinzo Seko
  • Publication number: 20090192336
    Abstract: A process for the production of an alcohol compound represented by the formula (3): wherein X1, X2, X3, X4, Z, R and n are as defined below, comprising reacting a phenol represented by the formula (1): wherein X1, X2, X3 and X4 independently represent a hydrogen atom, a halogen atom or an alkyl group having 1 to 3 carbon atoms; Z represents an oxygen atom or a sulfur atom; and R represents a halogen-substituted alkenyl group, with a haloalcohol represented by the formula (2): wherein Y represents a chlorine atom or a bromine atom; and n represents an integer of 2 or 3, in a biphase system composed of a water-immiscible organic solvent and an aqueous alkali metal hydroxide solution in the presence of a phase-transfer catalyst.
    Type: Application
    Filed: July 3, 2007
    Publication date: July 30, 2009
    Inventors: Toru Sakamoto, Shinzo Seko
  • Publication number: 20090018364
    Abstract: An object of the present invention is to industrially advantageously produce N-nitroisoureas or a salt thereof which is useful as a synthetic intermediate for pharmaceuticals and pesticides. The present invention relates to a process for producing a compound represented by the formula (2): wherein R1, R2 and R3 are as defined below, or a salt thereof, which comprises reacting a compound represented by the formula (1): wherein R1 represents an optionally substituted straight-chain or branched C1 to C6 alkyl group, R2 and R3 are the same or different and represent an optionally substituted straight-chain or branched C1 to C6 alkyl group, a cycloalkyl group or a substituted aryl group, or R2 and R3 simultaneously represent a hydrogen atom, or a salt thereof with a nitrating agent in the presence of sulfur trioxide.
    Type: Application
    Filed: March 15, 2007
    Publication date: January 15, 2009
    Inventors: Kazuyuki Yamagata, Shinzo Seko
  • Patent number: 7439357
    Abstract: A process for preparing a thiazole compound of formula (3): wherein X1 represents a hydrogen atom or a halogen atom comprising reacting a compound of formula (1): wherein X1 is as defined above, and X2 represents a halogen atom, with ammonia and formaldehyde to obtain a hexahydrotriazine compound of formula (2): wherein X1 is as defined above, and hydrolyzing the compound of formula (2).
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: October 21, 2008
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Naoyuki Takano, Shinzo Seko, Kazuyuki Tanaka
  • Publication number: 20070197803
    Abstract: A process for preparing a thiazole compound of formula (3): wherein X1 represents a hydrogen atom or a halogen atom comprising reacting a compound of formula (1): wherein X1 is as defined above, and X2 represents a halogen atom, with ammonia and formaldehyde to obtain a hexahydrotriazine compound of formula (2): wherein X1 is as defined above, and hydrolyzing the compound of formula (2).
    Type: Application
    Filed: June 10, 2005
    Publication date: August 23, 2007
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Naoyuki Takano, Shinzo Seko, Kazuyuki Tanaka
  • Patent number: 6806387
    Abstract: The present invention relates to a process for producing an allyl sulfone derivative represented by the formula (3): wherein Ar is an optionally substituted aryl group, and the corrugated line means either one of E/Z geometrical isomers, or a mixture thereof, which is an intermediate for producing vitamin A, which process is characterized by reacting an aryl sulfinic acid or a salt thereof represented by the formula (2): ArSO2M  (2) wherein Ar is as defined above, and M is hydrogen atom, sodium atom or potassium atom, with an allyl halide derivative represented by the formula (1): wherein X is a halogen atom, and Ar and the corrugated line are as defined above.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: October 19, 2004
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Toshiya Takahashi, Hirotada Kakiya, Shinzo Seko
  • Publication number: 20040204612
    Abstract: A disulfone compound represented by the general formula (3): 1
    Type: Application
    Filed: March 2, 2004
    Publication date: October 14, 2004
    Inventors: Shinzo Seko, Naoto Konya, Toshiya Takahashi
  • Patent number: 6784321
    Abstract: There are disclosed a disulfone compound of formula (1): wherein Ar denotes an aryl group that may have a substituent, R1 denotes a hydrogen atom or a protective group of a hydroxyl group and the wavy line means that the disulfone compound is an E or Z geometrical isomer or a mixture thereof, a method for producing the same, intermediate compounds therefore and a process for producing retinol through the disulfone compound.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: August 31, 2004
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Toshiya Takahashi, Shinzo Seko, Kazutaka Kimura, Noriyuki Doi, Naoto Konya
  • Publication number: 20040082814
    Abstract: There are disclosed a disulfone compound of formula (1): 1
    Type: Application
    Filed: October 20, 2003
    Publication date: April 29, 2004
    Applicant: Sumitomo Chemical Company, Limited
    Inventors: Toshiya Takahashi, Shinzo Seko, Kazutaka Kimura, Noriyuki Doi, Naoto Konya
  • Publication number: 20040054233
    Abstract: The present invention relates to a process for producing an allyl sulfone derivative represented by the formula (3): 1
    Type: Application
    Filed: June 30, 2003
    Publication date: March 18, 2004
    Inventors: Toshiya Takahasi, Hirotaka Kakiya, Shinzo Seko