Patents by Inventor Shirlynn Chen

Shirlynn Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID STATE FORMS OF A POTENT HCV INHIBITOR
    Publication number: 20140057928
    Abstract: This invention relates to novel sodium salt forms of the following Compound (1), and methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of Hepatitis C Viral (HCV) infection:
    Type: Application
    Filed: October 30, 2013
    Publication date: February 27, 2014
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Rolf-Stefan BRICKL, Shirlynn CHEN, Jihchin CHUNG, Mayur Suryakant DUDHEDIA, Danping LI, Zhi-Hui LU, Siddharthya MUJUMDAR, Chitra TELANG, Richard J. VARSOLONA, Zeren WANG
  • Solid state forms of a potent HCV inhibitor
    Patent number: 8598183
    Abstract: This invention relates to novel sodium salt forms of the following Compound (1), and methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of Hepatitis C Viral (HCV) infection:
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: December 3, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Rolf-Stefan Brickl, Shirlynn Chen, Jihchin Chung, Mayur Suryakant Dudhedia, Danping Li, Zhi-Hui Lu, Siddharthya Mujumdar, Chitra Telang, Richard J. Varsolona, Zeren Wang
  • SOLID STATE FORMS OF A POTENT HCV INHIBITOR
    Publication number: 20120122887
    Abstract: This invention relates to novel sodium salt forms of the following Compound (1), and methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of Hepatitis C Viral (HCV) infection:
    Type: Application
    Filed: September 23, 2011
    Publication date: May 17, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Rolf-Stefan BRICKL, Shirlynn CHEN, Jihchin CHUNG, Mayur Suryakant DUDHEDIA, Danping LI, Zhi-Hui LU, Siddharthya MUJUMDAR, Chitra TELANG, Richard J. VARSOLONA, Zeren WANG
  • Pharmaceutical compositions for hepatitis C viral protease inhibitors
    Patent number: 7157424
    Abstract: Disclosed are pharmaceutical compositions of hepatitis C viral protease inhibitors, and methods of using these compositions for inhibiting the replication of the hepatitis C virus (HCV) and for the treatment of an HCV infection. These compositions are lipid based systems and comprise the hepatitis C viral protease inhibitor together with at least one pharmaceutically acceptable amine, at least one pharmaceutically acceptable base, at least one pharmaceutically acceptable oil and optionally one or more additional ingredients.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: January 2, 2007
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Shirlynn Chen, Xiaohui Mei, Zeren Wang
  • Class of surfactant-like materials
    Publication number: 20060068007
    Abstract: This invention generally refers to a novel class of surfactant-like material that promotes the solubility of poorly soluble compounds.
    Type: Application
    Filed: September 16, 2005
    Publication date: March 30, 2006
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Jinjiang Li, Shirlynn Chen, George Gereg, Mariotte Corson
  • Pharmaceutical compositions for hepatitis C viral protease inhibitors
    Patent number: 6828301
    Abstract: Disclosed are pharmaceutical compositions of hepatitis C viral protease inhibitors having improved bioavailability, and methods of using these compositions for inhibiting the replication of the hepatitis C virus (HCV) and for the treatment of an HCV infection. These compositions include co-solvent systems, lipid based systems, solid dispersions and granulations, and all comprise the hepatitis C viral protease inhibitor, at least one pharmaceutically acceptable amine and optionally one or more additional ingredients.
    Type: Grant
    Filed: February 4, 2003
    Date of Patent: December 7, 2004
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Shirlynn Chen, Xiaohui Mei
  • Pharmaceutical compositions for hepatitis C viral protease inhibitors
    Publication number: 20040229776
    Abstract: Disclosed are pharmaceutical compositions of hepatitis C viral protease inhibitors, and methods of using these compositions for inhibiting the replication of the hepatitis C virus (HCV) and for the treatment of an HCV infection. These compositions are lipid based systems and comprise the hepatitis C viral protease inhibitor together with at least one pharmaceutically acceptable amine, at least one pharmaceutically acceptable base, at least one pharmaceutically acceptable oil and optionally one or more additional ingredients.
    Type: Application
    Filed: March 23, 2004
    Publication date: November 18, 2004
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Shirlynn Chen, Xiaohui Mei, Zeren Wang
  • Potent inhibitor of HCV serine protease
    Publication number: 20040138109
    Abstract: Disclosed are oral pharmaceutical compositions, kits and methods of treating and preventing Hepatitis C Viral (HCV) infections wherein the following Compound (1), a potent inhibitor of HCV serine protease, or a pharmaceutically acceptable salt thereof, is administered in a selected dosage range: 1
    Type: Application
    Filed: September 16, 2003
    Publication date: July 15, 2004
    Applicants: Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim Pharma GmbH & CO. KG
    Inventors: Shirlynn Chen, Jens Oliver Croenlein, Gerhard Nehmiz, Gerhard Steinmann, Jocelyn Abella Gunn, Phuong Do Costa
  • Pharmaceutical compositions for hepatitis C viral protease inhibitors
    Publication number: 20040033959
    Abstract: Disclosed are pharmaceutical compositions of hepatitis C viral protease inhibitors having improved bioavailability, and methods of using these compositions for inhibiting the replication of the hepatitis C virus (HCV) and for the treatment of an HCV infection. These compositions include co-solvent systems, lipid based systems, solid dispersions and granulations, and all comprise the hepatitis C viral protease inhibitor, at least one pharmaceutically acceptable amine and optionally one or more additional ingredients.
    Type: Application
    Filed: July 16, 2003
    Publication date: February 19, 2004
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Shirlynn Chen, Xiaohui Mei
  • Pharmaceutical compositions for hepatitis C viral protease inhibitors
    Publication number: 20030195228
    Abstract: Disclosed are pharmaceutical compositions of hepatitis C viral protease inhibitors having improved bioavailability, and methods of using these compositions for inhibiting the replication of the hepatitis C virus (HCV) and for the treatment of an HCV infection. These compositions include co-solvent systems, lipid based systems, solid dispersions and granulations, and all comprise the hepatitis C viral protease inhibitor, at least one pharmaceutically acceptable amine and optionally one or more additional ingredients.
    Type: Application
    Filed: February 4, 2003
    Publication date: October 16, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Shirlynn Chen, Xiaohui Mei
  • Oral dosage self-emulsifying formulations of pyranone protease inhibitors
    Patent number: 6555558
    Abstract: A microemulsion of pyranone protease inhibitor compounds that is substantially free of alcohol and propylene glycol comprising a pyranone protease inhibitor, one or more pharmaceutically acceptable surfactants, and a polyethylene glycol solvent having a mean molecular weight of greater than 300 but lower than 600, and a lipophilic component comprising medium chain mono- and di-glycerides, and optionally a basic amine.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: April 29, 2003
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Shirlynn Chen, Jocelyn A. Gunn
  • Oral dosage self-emulsifying formulations of pyranone protease inhibitors
    Publication number: 20020115690
    Abstract: A microemulsion of pyranone protease inhibitor compounds that is substantially free of alcohol and propylene glycol comprising a pyranone protease inhibitor, one or more pharmaceutically acceptable surfactants, and a polyethylene glycol solvent having a mean molecular weight of greater than 300 but lower than 600, and a lipophilic component comprising medium chain mono- and di-glycerides, and optionally a basic amine.
    Type: Application
    Filed: October 30, 2001
    Publication date: August 22, 2002
    Inventors: Shirlynn Chen, Jocelyn A. Gunn