Patents by Inventor Shiwen Zhang
Shiwen Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11905224Abstract: The present application provides a method for fully recycling kitchen waste by using Hermetia illucens L. and aerobic microorganisms. The method includes first performing solid-liquid separation on the kitchen waste; then using the filtrate obtained through separation to feed young larvae of Hermetia illucens L. to convert salt in the filtrate into body fluid of Hermetia illucens L. in a larval stage, and using the kitchen waste filter residue to feed 2nd-6th-instar larvae of Hermetia illucens L. respectively; separating insects and insect feces residue in a timely manner, so as to reduce a salt content of insect feces and improve transabdominal transformation efficiency of Hermetia illucens L. and quality of the insect manure; and finally implementing full resource utilization through aerobic composting and insect drying and sterilization treatment.Type: GrantFiled: April 28, 2023Date of Patent: February 20, 2024Assignees: NANJING UNIVERSITY, LISHUI INSTITUTE OF ECOLOGICAL ENVIRONMENT, NANJING UNIVERSITYInventors: Zengwei Yuan, Mingjin Cheng, Xiang Cheng, Shiwen Zhang
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Publication number: 20230331637Abstract: The present application provides a method for fully recycling kitchen waste by using Hermetia illucens L. and aerobic microorganisms. The method includes first performing solid-liquid separation on the kitchen waste; then using the filtrate obtained through separation to feed young larvae of Hermetia illucens L. to convert salt in the filtrate into body fluid of Hermetia illucens L. in a larval stage, and using the kitchen waste filter residue to feed 2nd-6th-instar larvae of Hermetia illucens L. respectively; separating insects and insect feces residue in a timely manner, so as to reduce a salt content of insect feces and improve transabdominal transformation efficiency of Hermetia illucens L. and quality of the insect manure; and finally implementing full resource utilization through aerobic composting and insect drying and sterilization treatment.Type: ApplicationFiled: April 28, 2023Publication date: October 19, 2023Applicants: NANJING UNIVERSITY, LISHUI INSTITUTE OF ECOLOGICAL ENVIRONMENT, NANJING UNIVERSITYInventors: Zengwei YUAN, Mingjin CHENG, Xiang CHENG, Shiwen ZHANG
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Publication number: 20230303714Abstract: Described and provided herein are novel antibodies for Claudin 18.2. Also described and provided are pharmaceutical compositions of the antibodies and methods of use for the treatment of cancer.Type: ApplicationFiled: November 21, 2022Publication date: September 28, 2023Applicants: AskGene Pharma Inc., Jiangsu AoSaiKang Pharmaceutical Co., Ltd.Inventors: Yuefeng Lu, Kurt Shanebeck, Lu Li, Lei Liu, Shiwen Zhang, Lan Yang, Jian-Feng Lu
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Patent number: 11636744Abstract: This disclosure includes technologies for action recognition in general. The disclosed system may automatically detect various types of actions in a video, including reportable actions that cause shrinkage in a practical application for loss prevention in the retail industry. Further, appropriate responses may be invoked if a reportable action is recognized. In some embodiments, a three-branch architecture may be used in a machine learning model for action and/or activity recognition. The three-branch architecture may include a main branch for action recognition, an auxiliary branch for learning/identifying an actor (e.g., human parsing) related to an action, and an auxiliary branch for learning/identifying a scene related to an action. In this three-branch architecture, the knowledge of the actor and the scene may be integrated in two different levels for action and/or activity recognition.Type: GrantFiled: February 5, 2021Date of Patent: April 25, 2023Assignee: Shenzhen Malong Technologies Co., Ltd.Inventors: Weilin Huang, Shiwen Zhang, Limin Wang, Sheng Guo, Matthew Robert Scott
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Patent number: 11505618Abstract: Described and provided herein are novel antibodies for Claudin 18.2. Also described and provided are pharmaceutical compositions of the antibodies and methods of use for the treatment of cancer.Type: GrantFiled: July 18, 2019Date of Patent: November 22, 2022Assignees: AskGene Pharma Inc., Jiangsu AoSaiKang Pharmaceutical Co., Ltd.Inventors: Yuefeng Lu, Kurt Shanebeck, Lu Li, Lei Liu, Shiwen Zhang, Lan Yang, Jian-Feng Lu
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Publication number: 20220306714Abstract: The present disclosure provides novel isolated IL-2 fusion molecules that preferentially activate regulatory T cells (Treg) in vitro and in vivo. Further included are methods of making and using said novel fusion molecules to treat inflammatory and autoimmune diseases.Type: ApplicationFiled: August 12, 2020Publication date: September 29, 2022Applicant: ASKGENE PHARMA, INC.Inventors: Chen YAO, Chunxiao YU, Yuefeng LU, Liqin LIU, Kurt SHANEBECK, Shiwen ZHANG
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Patent number: 11445711Abstract: Disclosed are an intelligent separation and drying system for maggots and a method of operating the same. The intelligent separation and drying system includes an intelligent light control unit, an intelligent scraping unit, a separation unit, a drying unit, a travelling unit and a central control unit. The central control unit is connected to other units through signals. Multidisciplinary techniques, including spectrum analysis, machine learning algorithm and artificial neural network, are combined to automatically, systematically, intelligently and continuously separate maggots and maggot feed as well as dry the maggots with high efficiency in a clean manner.Type: GrantFiled: July 9, 2020Date of Patent: September 20, 2022Assignee: Lishui Institute of Ecology and Environment, Nanjing UniversityInventors: Zengwei Yuan, Shiwen Zhang, Zumao Qin, Xinrong Zhou, Tianming Chen
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Publication number: 20210248377Abstract: This disclosure includes technologies for video recognition in general. The disclosed system can automatically detect various types of actions in a video, including reportable actions that cause shrinkage in a practical application for loss prevention in the retail industry. The temporal evolution of spatio-temporal features in the video are used for action recognition. Such features may be learned via a 4D convolutional operation, which is adapted to model low-level features based on a residual 4D block. Further, appropriate responses may be invoked if a reportable action is recognized.Type: ApplicationFiled: June 9, 2020Publication date: August 12, 2021Inventors: Weilin HUANG, Shiwen ZHANG, Sheng GUO, Limin WANG, Matthew Robert SCOTT
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Publication number: 20210248885Abstract: This disclosure includes technologies for action recognition in general. The disclosed system may automatically detect various types of actions in a video, including reportable actions that cause shrinkage in a practical application for loss prevention in the retail industry. Further, appropriate responses may be invoked if a reportable action is recognized. In some embodiments, a three-branch architecture may be used in a machine learning model for action and/or activity recognition. The three-branch architecture may include a main branch for action recognition, an auxiliary branch for learning/identifying an actor (e.g., human parsing) related to an action, and an auxiliary branch for learning/identifying a scene related to an action. In this three-branch architecture, the knowledge of the actor and the scene may be integrated in two different levels for action and/or activity recognition.Type: ApplicationFiled: February 5, 2021Publication date: August 12, 2021Inventors: Weilin HUANG, Shiwen ZHANG, Limin WANG, Sheng GUO, Matthew Robert SCOTT
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Publication number: 20210144905Abstract: Disclosed are an intelligent separation and drying system for maggots and a method of operating the same. The intelligent separation and drying system includes an intelligent light control unit, an intelligent scraping unit, a separation unit, a drying unit, a travelling unit and a central control unit. The central control unit is connected to other units through signals. Multidisciplinary techniques, including spectrum analysis, machine learning algorithm and artificial neural network, are combined to automatically, systematically, intelligently and continuously separate maggots and maggot feed as well as dry the maggots with high efficiency in a clean manner.Type: ApplicationFiled: July 9, 2020Publication date: May 20, 2021Inventors: Zengwei Yuan, Shiwen Zhang, Zumao Qin, Xinrong Zhou, Tianming Chen
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Patent number: 10961194Abstract: Provided is a method for purifying ropinirole hydrochloride (4-2-di-n-propylaminoethyl-1,3-dihydro-2H-indole-2-ketohydrochloride). The method comprises: adding ropinirole hydrochloride containing a monopropyl impurity A into water, adding organic solvent, stirring and dissolving at room temperature, adding alkali, stirring, standing, demixing, and removing an aqueous layer; optionally, drying the organic layer by using anhydrous magnesium sulfate, and filtering; and adding acyl chloride or acid anhydride into the organic layer, stirring, concentrating the organic layer to be dry, adding an organic solvent into the obtained oily matter, adding concentrated hydrochloric acid, and stirring, so as to obtain the ropinirole hydrochloride. By using the method, the impurity A in the ropinirole hydrochloride can be effectively removed, and the ropinirole hydrochloride can be obtained with a high yield and a high purity, so that the impurity A is controlled and the purity of the product reaches a medicinal standard.Type: GrantFiled: June 16, 2017Date of Patent: March 30, 2021Assignees: ZHEJIANG HUAHAI LICHENG PHARMACEUTICAL CO., LTD., ZHEJIANG HUAHAI PHARMACEUTICALS CO., LTD.Inventors: Guoliang Tu, Zhongming Xu, Tao Zhou, Wenfeng Huang, Shiwen Zhang
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Patent number: 10713493Abstract: This disclosure includes technologies for video recognition in general. The disclosed system can automatically detect various types of actions in a video, including reportable actions that cause shrinkage in a practical application for loss prevention in the retail industry. The temporal evolution of spatio-temporal features in the video are used for action recognition. Such features may be learned via a 4D convolutional operation, which is adapted to model low-level features based on a residual 4D block. Further, appropriate responses may be invoked if a reportable action is recognized.Type: GrantFiled: February 6, 2020Date of Patent: July 14, 2020Assignee: SHENZHEN MALONG TECHNOLOGIES CO., LTD.Inventors: Weilin Huang, Shiwen Zhang, Sheng Guo, Limin Wang, Matthew Robert Scott
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Patent number: 10715899Abstract: The present invention discloses a wind noise prevention microphone and an earphone cable control apparatus. The microphone comprises: a microphone chamber enclosed by a bottom and a first side wall; a microphone unit arranged inside the microphone chamber and of which a sound pick-up hole of the microphone unit is arranged opposite to the bottom, a set gap being arranged between the sound pick-up hole and the bottom; and a sound channel in communication with the sound pick-up hole and an outer space, and led out of the first side wall. The sound channel of the microphone is arranged on a side of the sound pick-up hole of the microphone, other than directly opposite to the sound pick-up hole of the microphone, which can effectively reduce wind noise and improve the sound pick-up quality.Type: GrantFiled: December 19, 2016Date of Patent: July 14, 2020Assignee: GOERTEK INC.Inventors: Liyang Zhu, Mingjun Zuo, Shiwen Zhang, Jiangtao Xu
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Publication number: 20200172482Abstract: Provided is a method for purifying ropinirole hydrochloride (4-2-di-n-propylaminoethyl-1,3-dihydro-2H-indole-2-ketohydrochloride). The method comprises: adding ropinirole hydrochloride containing a monopropyl impurity A into water, adding organic solvent, stirring and dissolving at room temperature, adding alkali, stirring, standing, demixing, and removing an aqueous layer; optionally, drying the organic layer by using anhydrous magnesium sulfate, and filtering; and adding acyl chloride or acid anhydride into the organic layer, stirring, concentrating the organic layer to be dry, adding an organic solvent into the obtained oily matter, adding concentrated hydrochloric acid, and stirring, so as to obtain the ropinirole hydrochloride. By using the method, the impurity A in the ropinirole hydrochloride can be effectively removed, and the ropinirole hydrochloride can be obtained with a high yield and a high purity, so that the impurity A is controlled and the purity of the product reaches a medicinal standard.Type: ApplicationFiled: June 16, 2017Publication date: June 4, 2020Inventors: Guoliang TU, Zhongming XU, Tao ZHOU, Wenfeng HUANG, Shiwen ZHANG
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Publication number: 20200040101Abstract: Described and provided herein are novel antibodies for Claudin 18.2. Also described and provided are pharmaceutical compositions of the antibodies and methods of use for the treatment of cancer.Type: ApplicationFiled: July 18, 2019Publication date: February 6, 2020Applicants: AskGene Pharma Inc., Jiangsu AoSaiKang Pharmaceutical Co., Ltd.Inventors: Yuefeng Lu, Kurt Shanebeck, Lu Li, Lei Liu, Shiwen Zhang, Lan Yang, Jian-Feng Lu
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Publication number: 20190297406Abstract: The present invention discloses a wind noise prevention microphone and an earphone cable control apparatus. The microphone comprises: a microphone chamber enclosed by a bottom and a first side wall; a microphone unit arranged inside the microphone chamber and of which a sound pick-up hole of the microphone unit is arranged opposite to the bottom, a set gap being arranged between the sound pick-up hole and the bottom; and a sound channel in communication with the sound pick-up hole and an outer space, and led out of the first side wall. The sound channel of the microphone is arranged on a side of the sound pick-up hole of the microphone, other than directly opposite to the sound pick-up hole of the microphone, which can effectively reduce wind noise and improve the sound pick-up quality.Type: ApplicationFiled: December 19, 2016Publication date: September 26, 2019Inventors: Liyang ZHU, Mingjun ZUO, Shiwen ZHANG, Jiangtao XU
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Publication number: 20190128785Abstract: The invention relates to reagents, solutions, kits, and methods for tissue clearing.Type: ApplicationFiled: October 31, 2018Publication date: May 2, 2019Inventors: Hu Zhao, Dian Jing, Shiwen Zhang, Wenjing Luo
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Publication number: 20180055944Abstract: The present invention relates to compositions and methods using an isolated chimeric molecule, wherein the isolated chimeric molecule comprises an antibody, one or more albumin motifs, optional peptide linkers, and two or more antibiotics or cytotoxic drug molecules conjugated to the unpaired cysteine residues, optionally through linkers. In one embodiment, each of the said albumin motifs in the isolated chimeric molecule contains 2 or more unpaired cysteine residues. In another embodiment, the said antibody in the isolated chimeric molecule targets antigens on cancer cells or drug-resistant bacteria. In another embodiment, the cancer cells have upregulated macropinocytosis. In another embodiment, the cancer cells contain one or more mutations in their RAS family genes. The compositions of the invention are used to treat drug-resistant bacterial infections and cancers, preferably the ones with upregulated macropinocytosis, and the ones containing one or more mutations in their RAS family genes.Type: ApplicationFiled: August 1, 2017Publication date: March 1, 2018Applicant: AskGene Pharma Inc.Inventors: Yuefeng Lu, Jian-Feng Lu, Lan Yang, Lu Li, Lei Liu, Shiwen Zhang
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Patent number: 9169145Abstract: A method for purifying and sterilizing water using nano catalytic microelectrolysis and an apparatus therefore including three units of a nano catalytic microelectrolysis device, a sand filtration and a precise filtration are provided. 1/20 to ? of raw water is delivered into the nano catalytic microelectrolysis. 19/20 to ? of raw water is directly delivered into a neutralization tank to be mixed with nano catalytic microelectrolysis water to kill microorganism, algae and plankton and force suspended solids, colloid, charged particles and etc. to form into relatively large particles which are removed by the precise filtration unit; heavy metal ions gather at a cathode of the microelectrolysis to form cathode sediment to be removed; organic compounds are oxidatively decomposed by strongly oxidative substances produced by the microelectrolysis; phosphate ions move towards a cathode polarization layer and act with divalent cations on a cathode surface to produce phosphate precipitate to be removed.Type: GrantFiled: January 28, 2011Date of Patent: October 27, 2015Assignee: Boying Xiamen Science and Technology Co., Ltd.Inventor: Shiwen Zhang
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Patent number: 8728319Abstract: A purifying device and a process for deeply treating printing and dyeing wastewater are provided. The device includes a nanometer catalytic microelectrolysis system, a membrane filtration and separation system and a a membrane washing regeneration system. The method includes the following steps of: drawing the printing and dyeing wastewater by a first water pump (12), pumping a first part of the wastewater into a nanometer catalytic microelectrolysis tank (13) to perform catalysis microelectrolysis, and a second part of the wastewater into a neutralization tank (16) to mix with the water from the nanometer catalytic microelectrolysis tank (13) to precipitate, filtering the wastewater by a sand filtration tank (17), and then pumping the wastewater into an adsorption and filteration device of granular active carbon (18) for adsorption and filtration. The process has lower cost and higher energy efficiency, and can realize recycled water to be reused.Type: GrantFiled: January 26, 2011Date of Patent: May 20, 2014Assignee: Boying Xiamen Science and Technology Co., Ltd.Inventor: Shiwen Zhang