Patents by Inventor Shlomo Margel

Shlomo Margel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200392288
    Abstract: Anti-fogging proteinoid compounds are disclosed. Processes of preparing the antifogging proteinoid compositions and incorporating thereof in or on a substrate are also disclosed. Articles of manufacturing incorporating such compositions are also disclosed.
    Type: Application
    Filed: November 22, 2018
    Publication date: December 17, 2020
    Inventors: Shlomo MARGEL, Michal KOLITZ DOMB, Elisheva SASON
  • Patent number: 10738200
    Abstract: Nanoparticles of N-halamine-derivatized crosslinked polyamide. Process of preparing the polymeric nanoparticles per se and incorporated in or on a substrate. Uses of the polymeric nanoparticles and of substrates incorporating same, particularly for reducing a formation of organic-based contaminants, e.g., load of a microorganism or of a biofilm.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: August 11, 2020
    Assignee: BAR ILAN UNIVERSITY
    Inventors: Shlomo Margel, Ehud Banin, Ori Gutman, Michal Natan
  • Publication number: 20200171534
    Abstract: A composition comprising nano- or micro-particles grafted onto a surface are disclosed. Process of preparing the compositions and methods of using the same, such as for anti-fogging, anti-fouling and anti-scratching are provided.
    Type: Application
    Filed: March 21, 2019
    Publication date: June 4, 2020
    Inventors: Shlomo MARGEL, Sharon BRETLER, Sarit COHEN, Naftali KANOVSKY
  • Patent number: 10508126
    Abstract: A compound or a polymer is claimed. A first formula can be wherein X is H, CH3, CN, phenyl, substituted phenyl, (CH2)mZ, or phenyl(CH2)mZ; T is O, N, S or NH; m equals 1 to 20; n equals 1-100; and Z is CN, NH2, Thiol, OH, or CO2H. The second formula is: wherein X is H, CH3, CN, phenyl, substituted phenyl, (CH2)mZ, or phenyl(CH2)mZ; and Z is CN, NH2, Thiol, OH, or CO2H. The third formula is wherein: R1, R2, R3, and R4 are independently: H, CH3, OH, or a halogen.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: December 17, 2019
    Assignee: Bar-Ilan University
    Inventors: Shlomo Margel, Dana Mizrahi, Eran Gluz, Ravit Chen
  • Publication number: 20190247318
    Abstract: Proteinoid compounds characterized by a molecular weight (Mw) of at least 15,000 Da, processes of preparing such compounds and methods of use thereof, are provided. A method of monitoring the presence and metastases of cancer in a body of an individual is further disclosed.
    Type: Application
    Filed: April 22, 2019
    Publication date: August 15, 2019
    Inventors: Shlomo MARGEL, Michal KOLITZ DOMB, Stella KIEL, Elisheva SASON
  • Patent number: 10300024
    Abstract: Proteinoid compounds characterized by a molecular weight (Mw) of at least 15,000 Da, processes of preparing such compounds and methods of use thereof, are provided. A method of monitoring the presence and metastases of cancer in a body of an individual is further disclosed.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: May 28, 2019
    Assignee: BAR-ILAN UNIVERSITY
    Inventors: Shlomo Margel, Michal Kolitz Domb, Stella Kiel, Elisheva Sason
  • Publication number: 20190119436
    Abstract: Disclosed methyl styrene farmin compounds, and crosslinked polymeric backbones comprising same. Further disclosed microsized and nanosized polymeric particles comprising polyisothiouronium methylstyrene (PITMS) and/or poly(methyl styrene farmin) or a derivative thereof, and uses thereof in, for example, reducing or preventing growth of microorganisms.
    Type: Application
    Filed: March 28, 2017
    Publication date: April 25, 2019
    Inventors: Shlomo MARGEL, Sarit COHEN
  • Publication number: 20190106520
    Abstract: Microparticles and Nanoparticles crosslinked polymer derived from 2-(2?-hydroxy-5?-methacryloxyethylphenyl)-2H-benzotriazole or a derivative thereof, are disclosed. Process of preparing the polymeric nanoparticles per se and incorporated in or on a substrate are also disclosed. Uses of the polymeric nanoparticles and of substrates incorporating same, particularly for UV absorbing films, are also disclosed.
    Type: Application
    Filed: March 28, 2017
    Publication date: April 11, 2019
    Inventors: Shlomo MARGEL, Sarit COHEN
  • Publication number: 20190002706
    Abstract: Nanoparticles of N-halamine-derivatized crosslinked polyamide. Process of preparing the polymeric nanoparticles per se and incorporated in or on a substrate. Uses of the polymeric nanoparticles and of substrates incorporating same, particularly for reducing a formation of organic-based contaminants, e.g., load of a microorganism or of a biofilm.
    Type: Application
    Filed: September 6, 2018
    Publication date: January 3, 2019
    Inventors: Shlomo MARGEL, Ehud BANIN, Ori GUTMAN, Michal NATAN
  • Patent number: 10072161
    Abstract: Nanoparticles of N-halamine-derivatized crosslinked polyamide. Process of preparing the polymeric nanoparticles per se and incorporated in or on a substrate. Uses of the polymeric nanoparticles and of substrates incorporating same, particularly for reducing a formation of organic based contaminants, e.g., load of a microorganism or of a biofilm.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: September 11, 2018
    Assignee: BAR ILAN UNIVERSITY
    Inventors: Shlomo Margel, Ehud Banin, Ori Gutman, Michal Natan
  • Publication number: 20180155374
    Abstract: A compound or a polymer is claimed. A first formula can be wherein X is H, CH3, CN, phenyl, substituted phenyl, (CH2)mZ, or phenyl(CH2)mZ; T is O, N, S or NH; m equals 1 to 20; n equals 1-100; and Z is CN, NH2, Thiol, OH, or CO2H. The second formula is: wherein X is H, CH3, CN, phenyl, substituted phenyl, (CH2)mZ, or phenyl(CH2)mZ; and Z is CN, NH2, Thiol, OH, or CO2H. The third formula is wherein: R1, R2, R3, and R4 are independently: H, CH3, OH, or a halogen.
    Type: Application
    Filed: February 5, 2018
    Publication date: June 7, 2018
    Inventors: Shlomo MARGEL, Dana MIZRAHI, Eran GLUZ, Ravit CHEN
  • Patent number: 9884880
    Abstract: The present invention provides novel bisphosphonates vinylic monomers, polymers and particles that have utility as biologically active molecule (such as drugs) carriers, medical device coatings and for imaging/radiology applications, especially in bone and dental applications. The invention also provides methods of synthesizing the monomers, polymerizing the polymers, and assembling the particles of the invention.
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: February 6, 2018
    Assignee: Bar-Ilan University
    Inventors: Shlomo Margel, Dana Mizrahi, Eran Gluz, Ravit Chen
  • Publication number: 20170042827
    Abstract: Proteinoid compounds characterized by a molecular weight (Mw) of at least 15,000 Da, processes of preparing such compounds and methods of use thereof, are provided. A method of monitoring the presence and metastases of cancer in a body of an individual is further disclosed.
    Type: Application
    Filed: August 10, 2016
    Publication date: February 16, 2017
    Inventors: Shlomo MARGEL, Michal KOLITZ DOMB, Stella KIEL, Elisheva SASON
  • Publication number: 20170009084
    Abstract: Nanoparticles of N-halamine-derivatized crosslinked polyamide. Process of preparing the polymeric nanoparticles per se and incorporated in or on a substrate. Uses of the polymeric nanoparticles and of substrates incorporating same, particularly for reducing a formation of organic based contaminants, e.g., load of a microorganism or of a biofilm.
    Type: Application
    Filed: January 22, 2015
    Publication date: January 12, 2017
    Inventors: Shlomo MARGEL, Ehud BANIN, Ori GUTMAN, Michal NATAN
  • Patent number: 9295736
    Abstract: The invention provides nanoparticles consisting of a polymer which is a metal chelating agent coated with a magnetic metal oxide, wherein at least one active agent is covalently bound to the polymer, said nanoparticles may optionally further comprise at least one active agent physically or covalently bound to the outer surface of the magnetic metal oxide. Pharmaceutical compositions comprising these nanoparticles may be used, inter alia, for detection and treatment of tumors and inflammations.
    Type: Grant
    Filed: September 24, 2008
    Date of Patent: March 29, 2016
    Assignees: Bar Ilan University, Henry Ford Health System
    Inventors: Shlomo Margel, Benny Perlstein, Chaya Brodie, Tom Mikkelsen
  • Publication number: 20150166585
    Abstract: The present invention provides novel bisphosphonates vinylic monomers, polymers and particles that have utility as biologically active molecule (such as drugs) carriers, medical device coatings and for imaging/radiology applications, especially in bone and dental applications. The invention also provides methods of synthesizing the monomers, polymerizing the polymers, and assembling the particles of the invention.
    Type: Application
    Filed: May 20, 2013
    Publication date: June 18, 2015
    Inventors: Shlomo Margel, Dana Mizrahi, Eran Gluz, Ravit Chen
  • Publication number: 20130030282
    Abstract: The present invention discloses Near Infrared (NIR) fluorescent albumin nanoparticles having a structure selected from a core structure or a core-shell structure. Also disclosed are a process of preparing these NIR fluorescent albumin nanoparticles, and a method of in vivo detection of pathologies, in particular cancer pathology, by using administering these NIR fluorescent albumin nanoparticles to a patient.
    Type: Application
    Filed: July 17, 2012
    Publication date: January 31, 2013
    Applicant: BAR ILAN UNIVERSITY
    Inventors: Shlomo Margel, Sarit Cohen, Enav Corem Salkmon, Michal Pellach
  • Publication number: 20120184642
    Abstract: The present invention relates to embolization material for therapeutic use, wherein said material is visible via more than one imaging technique.
    Type: Application
    Filed: July 6, 2010
    Publication date: July 19, 2012
    Inventors: Soenke Bartling, Shlomo Margel, Hagit Aviv
  • Publication number: 20120141380
    Abstract: The invention provides nanoparticles consisting of a polymer which is a metal chelating agent coated with a magnetic metal oxide, wherein at least one active agent is covalently bound to the polymer, said nanoparticles may optionally further comprise at least one active agent physically or covalently bound to the outer surface of the magnetic metal oxide. Pharmaceutical compositions comprising these nanoparticles may be used, inter alia, for detection and treatment of tumors and inflammations.
    Type: Application
    Filed: December 22, 2011
    Publication date: June 7, 2012
    Applicants: HENRY FORD HOSPITAL, BAR ILAN UNIVERSITY
    Inventors: Shlomo Margel, Benny Perlstein, Chaya Brodie, Tom Mikkelsen
  • Patent number: 8003079
    Abstract: Nanoparticles having an average particle size of less than 2000 nm, wherein said nanoparticles comprise a polymer having pendant cleavable iodine substituted groups are provided. Processes for preparing the nanoparticles and their use as a contrast agent for X-ray imaging are also described.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: August 23, 2011
    Assignee: Bar-Ilan University
    Inventors: Shlomo Margel, Anna Galperin