Patents by Inventor Sho SHINOHARA

Sho SHINOHARA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230098487
    Abstract: A method for analyzing a cause of prolonging coagulation time of a blood specimen includes: adding a calcium solution to a first sample resulting from a first waiting time from mixing of a blood specimen from a subject and a measurement reagent for an activated partial thromboplastin time; obtaining a first coagulation time and/or a first parameter regarding a differential of a coagulation waveform, for the first sample; adding the calcium solution to a second sample resulting from a second waiting time, which is longer than the first waiting time, from mixing of the blood specimen from the subject and the measurement reagent; obtaining a second coagulation time and/or a second parameter regarding a differential of a coagulation waveform, for the second sample; and obtaining information regarding a cause of prolonging a coagulation time, on the basis of the first and second coagulation time and/or the first and second parameter.
    Type: Application
    Filed: September 28, 2022
    Publication date: March 30, 2023
    Applicants: NIIGATA UNIVERSITY, SYSMEX CORPORATION
    Inventors: Takeshi SUZUKI, Masato MATSUDA, Masato MORIYAMA, Sho SHINOHARA, Keisuke KITANO, Tsukasa SUETAKE, Yutaka KOMIYAMA
  • Patent number: 11268949
    Abstract: A blood analysis method includes: acquiring optical information which changes over time from a mixed liquid of a blood sample and a reagent for coagulation time measurement after mixing the blood sample and the reagent, and acquiring information related to a coagulation time and information related to a number of platelets in the blood sample based on the acquired optical information.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: March 8, 2022
    Assignees: SYSMEX CORPORATION, UNIVERSITY OF YAMANASHI
    Inventors: Takeshi Suzuki, Yutaka Komiyama, Hiroshi Kurono, Sho Shinohara, Kaneo Satoh, Fuminori Kazama, Yugo Shimada
  • Patent number: 11150253
    Abstract: Disclosed is a method for analyzing a blood specimen, including the steps of: coagulating a blood specimen in the presence of an activating agent for fibrinolytic system to acquire a coagulation waveform; and acquiring information about fibrinolytic capacity of the blood specimen based on the acquired coagulation waveform.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: October 19, 2021
    Assignees: SYSMEX CORPORATION, PUBLIC UNIVERSITY CORPORATION NARA MEDICAL UNIVERSITY
    Inventors: Midori Shima, Keiji Nogami, Tomoko Matsumoto, Sho Shinohara, Nobuo Arai
  • Publication number: 20210302444
    Abstract: Disclosed is a method for measuring a blood coagulation activity, comprising: acquiring a parameter related to differentiation of a coagulation waveform in a blood specimen collected from a patient administered with (1) a polypeptide containing a sequence represented by SEQ ID NO: 1, or (2) a polypeptide containing a polypeptide having 95% or more identity with the sequence represented by SEQ ID NO: 1 and having an activity as a blood coagulation factor VIII; and acquiring an activity value of a blood coagulation factor VIII in the blood specimen based on the acquired parameter.
    Type: Application
    Filed: March 24, 2021
    Publication date: September 30, 2021
    Applicants: SYSMEX CORPORATION, KEIO UNIVERSITY, SOCIAL WELFARE ORGANIZATION SAISEIKAI IMPERIAL GIFT FOUNDATION, INC.
    Inventors: Sho SHINOHARA, Osamu KUMANO, Nobuo ARAI, Seiji MADOIWA, Yuta FUJIMORI
  • Patent number: 10739360
    Abstract: Disclosed is an analyzing method, for analyzing a blood specimen, which includes: mixing a blood specimen and a thrombin-containing reagent to coagulate the blood specimen, and obtaining a coagulation waveform; obtaining a value of a parameter concerning differentiation of the coagulation waveform, based on the coagulation waveform; and obtaining information concerning an amount of antigen of fibrinogen based on the obtained value of the parameter.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: August 11, 2020
    Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, SYSMEX CORPORATION
    Inventors: Atsuo Suzuki, Tadashi Matsushita, Sho Shinohara, Nobuo Arai
  • Publication number: 20190331659
    Abstract: A blood analysis method comprising, acquiring optical information which changes over time from a mixed liquid of a blood sample and a reagent for coagulation time measurement after mixing the blood sample and the reagent, and acquiring information related to a coagulation time and information related to a number of platelets in the blood sample based on the acquired optical information.
    Type: Application
    Filed: April 16, 2019
    Publication date: October 31, 2019
    Applicants: SYSMEX CORPORATION, University of Yamanashi
    Inventors: Takeshi Suzuki, Yutaka Komiyama, Hiroshi Kurono, Sho Shinohara, Kaneo Satoh, Fuminori Kazama, Yugo Shimada
  • Publication number: 20180306820
    Abstract: Disclosed is an analyzing method, for analyzing a blood specimen, which includes: mixing a blood specimen and a thrombin-containing reagent to coagulate the blood specimen, and obtaining a coagulation waveform; obtaining a value of a parameter concerning differentiation of the coagulation waveform, based on the coagulation waveform; and obtaining information concerning an amount of antigen of fibrinogen based on the obtained value of the parameter.
    Type: Application
    Filed: April 19, 2018
    Publication date: October 25, 2018
    Inventors: Atsuo SUZUKI, Tadashi MATSUSHITA, Sho SHINOHARA, Nobuo ARAI
  • Publication number: 20170315142
    Abstract: Disclosed is a method for analyzing a blood specimen, including the steps of: coagulating a blood specimen in the presence of an activating agent for fibrinolytic system to acquire a coagulation waveform; and acquiring information about fibrinolytic capacity of the blood specimen based on the acquired coagulation waveform.
    Type: Application
    Filed: April 27, 2017
    Publication date: November 2, 2017
    Applicants: SYSMEX CORPORATION, PUBLIC UNIVERSITY CORPORATION NARA MEDICAL UNIVERSITY
    Inventors: Midori SHIMA, Keiji NOGAMI, Tomoko MATSUMOTO, Sho SHINOHARA, Nobuo ARAI