Patents by Inventor Shoji Nakayama
Shoji Nakayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11415563Abstract: In an LC/MS/MS analysis: injecting a sample into a passage leading to a column group provided in a liquid chromatograph, the column group including a plurality of columns serially connected to each other and packed with different kinds of packing materials; supplying an eluant to one or a plurality of columns including a column located most downstream, to separate a portion of the target components in the sample in the one or plurality of columns, and sequentially elute those components from the most downstream column to perform mass spectrometry; and supplying a different eluant to one or a plurality of columns including the most downstream column, to separate at least a portion of the target components which stayed uneluted in the one or plurality of columns in the first analysis step, and sequentially elute those components from the most downstream column to perform mass spectrometry.Type: GrantFiled: April 13, 2017Date of Patent: August 16, 2022Assignees: SHIMADZU CORPORATION, NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIESInventors: Toshikazu Minohata, Jun Watanabe, Shoji Nakayama
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Publication number: 20200158701Abstract: In an LC/MS/MS analysis: injecting a sample into a passage leading to a column group provided in a liquid chromatograph, the column group including a plurality of columns serially connected to each other and packed with different kinds of packing materials; supplying an eluant to one or a plurality of columns including a column located most downstream, to separate a portion of the target components in the sample in the one or plurality of columns, and sequentially elute those components from the most downstream column to perform mass spectrometry; and supplying a different eluant to one or a plurality of columns including the most downstream column, to separate at least a portion of the target components which stayed uneluted in the one or plurality of columns in the first analysis step, and sequentially elute those components from the most downstream column to perform mass spectrometry.Type: ApplicationFiled: April 13, 2017Publication date: May 21, 2020Applicants: SHIMADZU CORPORATION, National Institute for Environmental StudiesInventors: Toshikazu MINOHATA, Jun WATANABE, Shoji NAKAYAMA
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Patent number: 10643830Abstract: A sample introduction unit 2 regularly collects a sample from a sample passage 1. A measurement unit 3 performs an LC/MS analysis for the collected sample. A spectrum matching judgment section 42 performs image recognition referring to mass spectra in a normal condition accumulated in a normal spectrum database 44, to determine whether a measured mass spectrum is in a normal condition. If the mass spectrum is non-normal, an abnormal peak locator 45 locates a peak which should not be detected in the normal condition, and an MSn analysis with the located peak selected as the target is performed in the measurement unit 3 under an MSn analysis execution commander 46. An identification processor 47 performs substance identification by a library search based on an acquired MSn spectrum. Upon successful identification, an alert commander 49 issues an alert. Thus, the system can automatically monitor hazardous substances with high accuracy.Type: GrantFiled: October 12, 2018Date of Patent: May 5, 2020Assignees: SHIMADZU CORPORATION, National Institute for Environmental StudiesInventors: Toshikazu Minohata, Shoji Nakayama
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Publication number: 20190115197Abstract: A sample introduction unit 2 regularly collects a sample from a sample passage 1. A measurement unit 3 performs an LC/MS analysis for the collected sample. A spectrum matching judgment section 42 performs image recognition referring to mass spectra in a normal condition accumulated in a normal spectrum database 44, to determine whether a measured mass spectrum is in a normal condition. If the mass spectrum is non-normal, an abnormal peak locator 45 locates a peak which should not be detected in the normal condition, and an MSn analysis with the located peak selected as the target is performed in the measurement unit 3 under an MSn analysis execution commander 46. An identification processor 47 performs substance identification by a library search based on an acquired MSn spectrum. Upon successful identification, an alert commander 49 issues an alert. Thus, the system can automatically monitor hazardous substances with high accuracy.Type: ApplicationFiled: October 12, 2018Publication date: April 18, 2019Applicants: SHIMADZU CORPORATION, NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIESInventors: Toshikazu MINOHATA, Shoji NAKAYAMA
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Patent number: 10056188Abstract: The present invention provides a producing method of R-T-B-based sintered magnets in which, the recovery chamber 40 includes inert gas introducing means 42, evacuating means 43, a carry-in port, a discharge port 40a, and a recovery container 60. The recovery step includes a carrying-in step of conveying a processing container 50 into the recovery chamber 40, a discharging step of discharging coarsely pulverized powder in the processing container 50 into the recovery chamber 40, a gas introducing step of introducing inert gas into the recovery chamber 40, and an alloy accommodating step of recovering the coarsely pulverized powder into the recovery container 60. Addition of pulverization aid is carried out in the alloy accommodating step. A remaining amount of coarsely pulverized powder in the recovery chamber 40, an oxygen-containing amount of the R-T-B-based sintered magnet is reduced, and magnetic properties are enhanced.Type: GrantFiled: January 26, 2012Date of Patent: August 21, 2018Assignee: HITACHI METALS, LTD.Inventors: Mitsuaki Mochizuki, Shoji Nakayama, Kazuhiro Sonoda
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Patent number: 9643253Abstract: A method and a device for recovering hydrogen pulverized powder of a raw-material alloy for rare-earth magnets capable of lowering the possibility that hydrogen pulverized powder remains in a recovery chamber; therefore, enhancing magnetic properties by reducing an oxygen content of an obtained rare-earth magnet. A processing container 50 is carried into a recovery chamber 40 from a processing chamber after inert gas is introduced into the recovery chamber 40. The raw-material alloy for rare-earth magnets in the processing container 50 is discharged into the recovery chamber 40 after the pressure in the recovery chamber 40 is reduced Thereafter, inert gas is introduced into the recovery chamber 40, and the raw-material alloy for rare-earth magnets is recovered into the recovery container 50 after a pressure in the recovery chamber 40 is set to a predetermined pressure by inert gas.Type: GrantFiled: January 27, 2015Date of Patent: May 9, 2017Assignee: HITACHI METALS, LTD.Inventors: Shoji Nakayama, Kazuhiro Sonoda, Jyunichi Sanai
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Patent number: 9463509Abstract: Provided are a recycle method and apparatus for effectively obtaining a recycled alloy powder which is hardly oxidized and which has substantially the same particle diameter as that of alloy powder used for forming a molded body, by using the molded body formed by press molding in manufacturing a rare earth sintered magnet.Type: GrantFiled: September 24, 2012Date of Patent: October 11, 2016Assignee: HITACHI METALS, LTD.Inventors: Shoji Nakayama, Mitsuaki Mochizuki
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Publication number: 20150158086Abstract: A method and a device for recovering hydrogen pulverized powder of a raw-material alloy for rare-earth magnets capable of lowering a possibility that hydrogen pulverized powder after hydrogen was pulverized remains in a recovery chamber and capable of enhancing magnetic properties by reducing an amount of oxygen of an obtained rare-earth magnet, a processing container 50 is carried into a recovery chamber 40 from a processing chamber through a carry-in port after inert gas was introduced into the recovery chamber 40 by inert gas introducing means 12, the raw-material alloy for rare-earth magnets in the processing container 50 is discharged into the recovery chamber 40 after the pressure in the recovery chamber 40 was reduced by evacuating means 33 and thereafter, inert gas is introduced into the recovery chamber 40 by inert gas introducing means 12, and the raw-material alloy for rare-earth magnets is recovered into the recovery container 50 from an discharge port 40a after a pressure in the recovery chamberType: ApplicationFiled: January 27, 2015Publication date: June 11, 2015Inventors: Shoji NAKAYAMA, Kazuhiro SONODA, Jyunichi SANAI
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Patent number: 8979973Abstract: A method and a device for recovering hydrogen pulverized powder of a raw-material alloy for rare-earth magnets capable of lowering a possibility that hydrogen pulverized powder after hydrogen was pulverized remains in a recovery chamber and capable of enhancing magnetic properties by reducing an amount of oxygen of an obtained rare-earth magnet, a processing container 50 is carried into a recovery chamber 40 from a processing chamber through a carry-in port after inert gas was introduced into the recovery chamber 40 by inert gas introducing means 12, the raw-material alloy for rare-earth magnets in the processing container 50 is discharged into the recovery chamber 40 after the pressure in the recovery chamber 40 was reduced by evacuating means 33 and thereafter, inert gas is introduced into the recovery chamber 40 by inert gas introducing means 12, and the raw-material alloy for rare-earth magnets is recovered into the recovery container 50 from an discharge port 40a after a pressure in the recovery chamberType: GrantFiled: July 7, 2010Date of Patent: March 17, 2015Assignee: Hitachi Metals, Ltd.Inventors: Shoji Nakayama, Kazuhiro Sonoda, Jyunichi Sanai
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Publication number: 20140239098Abstract: Provided are a recycle method and apparatus for effectively obtaining a recycled alloy powder which is hardly oxidized and which has substantially the same particle diameter as that of alloy powder used for forming a molded body, by using the molded body formed by press molding in manufacturing a rare earth sintered magnet.Type: ApplicationFiled: September 24, 2012Publication date: August 28, 2014Applicant: HITACHI METALS, LTD.Inventors: Shoji Nakayama, Mitsuaki Mochizuki
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Publication number: 20130309122Abstract: The present invention provides a producing method of R-T-B-based sintered magnets in which, the recovery chamber 40 includes inert gas introducing means 42, evacuating means 43, a carry-in port, a discharge port 40a, and a recovery container 60. The recovery step includes a carrying-in step of conveying a processing container 50 into the recovery chamber 40, a discharging step of discharging coarsely pulverized powder in the processing container 50 into the recovery chamber 40, a gas introducing step of introducing inert gas into the recovery chamber 40, and an alloy accommodating step of recovering the coarsely pulverized powder into the recovery container 60. Addition of pulverization aid is carried out in the alloy accommodating step. A remaining amount of coarsely pulverized powder in the recovery chamber 40, an oxygen-containing amount of the R-T-B-based sintered magnet is reduced, and magnetic properties are enhanced.Type: ApplicationFiled: January 26, 2012Publication date: November 21, 2013Applicant: HITACHI METALS, LTD.Inventors: Mitsuaki Mochizuki, Shoji Nakayama, Kazuhiro Sonoda
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Publication number: 20120125155Abstract: A method and a device for recovering hydrogen pulverized powder of a raw-material alloy for rare-earth magnets capable of lowering a possibility that hydrogen pulverized powder after hydrogen was pulverized remains in a recovery chamber and capable of enhancing magnetic properties by reducing an amount of oxygen of an obtained rare-earth magnet, a processing container 50 is carried into a recovery chamber 40 from a processing chamber through a carry-in port after inert gas was introduced into the recovery chamber 40 by inert gas introducing means 12, the raw-material alloy for rare-earth magnets in the processing container 50 is discharged into the recovery chamber 40 after the pressure in the recovery chamber 40 was reduced by evacuating means 33 and thereafter, inert gas is introduced into the recovery chamber 40 by inert gas introducing means 12, and the raw-material alloy for rare-earth magnets is recovered into the recovery container 50 from an discharge port 40a after a pressure in the recovery chamberType: ApplicationFiled: July 7, 2010Publication date: May 24, 2012Applicant: HITACHI METALS, LTD.Inventors: Shoji Nakayama, Kazuhiro Sonoda, Jyunichi Sanai
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Patent number: 6926575Abstract: On a faceplate having a phosphor layer and a metal back that are formed on a substrate, in a vacuum atmosphere, for instance an active Ba film is deposited as a getter film. Following this, while maintaining the vacuum atmosphere, the faceplate thereon the getter film is deposited and a rear plate having a plurality of electron emitters formed on a substrate are oppositely disposed to form a gap therebetween through a support frame, the gap being hermetically sealed. A flat panel display comprises the active Ba film formed on for instance the metal back as a getter film. Such getter film, while maintaining an activity, is disposed on an image display region in a vacuum vessel, having an excellent getter function.Type: GrantFiled: March 23, 2000Date of Patent: August 9, 2005Assignee: Kabushiki Kaisha ToshibaInventors: Shoji Nakayama, Shigeo Takenaka
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Patent number: 6143779Abstract: The present invention provides new benzofuranone derivatives and a method for producing the derivatives useful for a therapeutic agent for preventing and/or treating hormone dependent diseases.The present invention is a new benzofuranone derivative represented by a particular general formula (I). ##STR1## In the production, a particular benzofuranone compound and a particular benzaldehyde are reacted.Type: GrantFiled: December 7, 1998Date of Patent: November 7, 2000Assignee: Snow Brand Milk Products Co., Ltd.Inventors: Makoto Yoshihama, Masamichi Nakakoshi, Junji Nakamura, Shoji Nakayama
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Patent number: 6080781Abstract: The present invention provides new tetralone or benzopyranone derivatives and a method for producing the derivatives useful for a therapeutic agent for preventing and/or treating hormone dependent diseases. The present invention is a new tetralone or benzopyranone derivative represented by a particular general formula (I). ##STR1## wherein R.sub.1 and R.sub.2 represent hydrogen, a hydroxy group, an alkyloxy group or an aralkyloxy group, respectively, R.sub.3 -R.sub.7 represent hydrogen, a hydroxy group or a straight or branched alkyl, alkyloxy or aralkyloxy group having 1-6 carbon atoms, a halogen, an amino group or an alkylene dioxy group joined at R.sub.3 and R.sub.4, R.sub.4 and R.sub.5, R.sub.5 and R.sub.6, or R.sub.6 and R.sub.7, respectively, and A represents a methylene or oxygen.In the production, a particular tetralone or benzopyranone compound and a particular benzaldehyde compound are reacted.Type: GrantFiled: January 19, 1999Date of Patent: June 27, 2000Assignee: Snow Brand Milk Products Co., Ltd.Inventors: Makoto Yoshihama, Masamichi Nakakoshi, Junji Nakamura, Shoji Nakayama
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Patent number: 5126436Abstract: Physiologically active material SN-198C producing bacteria are disclosed which belong to Streptomyces species and products which have the following structural formula: ##STR1##Type: GrantFiled: May 25, 1990Date of Patent: June 30, 1992Assignee: Snow Brand Milk Products Company LimitedInventors: Kenichi Kimura, Shoji Nakayama, Nobuo Miyata
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Patent number: 5079377Abstract: Novel androst-4-ene-3,17-dione derivatives are disclosed. The group of these compounds has biological activities, in particular, the inhibiting activity on human placenta-derived estrogen-synthesizing enzyme. Therefore these compounds are expected to be utilized in the field of medical care, particularly as anticancer drugs.Type: GrantFiled: July 23, 1990Date of Patent: January 7, 1992Assignee: Snow Brand Milk Products Co., Ltd.Inventors: Makoto Yoshihama, Koji Tamura, Nobuo Miyata, Shoji Nakayama, Masamichi Nakakoshi
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Patent number: 4975368Abstract: Novel androst-4-ene-3,17-dione derivatives are disclosed. The group of these compounds has biological activities, in particular, the inhibiting activity on human placenta-derived estrogen-synthesizing enzyme. Therefore these compounds are expected to be utilized in the field of medical care, particularly as anticancer drugs.Type: GrantFiled: September 26, 1988Date of Patent: December 4, 1990Assignee: Snow Brand Milk Products Co., Ltd.Inventors: Makoto Yoshihama, Koji Tamura, Nobuo Miyata, Shoji Nakayama, Masamichi Nakakoshi
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Patent number: 4326846Abstract: This invention relates to a dental handpiece including turbine blades to be driven by a high-speed fluid under pressure to a turbine rotor chucking a cutting shaft, and blades are provided with openings or cutout portions located at both outside ends in a thrust direction of the blades so as to provide flange portions between the openings and the end portions of the blades and the peripheral width of the blades is larger than that of the high-speed fluid supply apperture.Type: GrantFiled: February 25, 1980Date of Patent: April 27, 1982Assignee: Kabushiki Kaisha Morita SeisakushoInventors: Hiroshi Sugai, Shoji Nakayama
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Patent number: 4209293Abstract: This invention relates to a driving mechanism of an air bearing journaled handpiece for dental treatment, the mechanism being improved in that even when a load contrary to the direction of rotation of a tool shaft such as cutting of the teeth acts upon the tool shaft in a dental operation, rotation of the tool shaft does not stop because of load resistance but enables the heretofore, unmaterialized medium-speed cutting (hereinafter referred to as "extension to medium-speed rotation") and makes it possible to obtain improved torque during high-speed rotation in addition to the extension to medium-speed rotation.Type: GrantFiled: March 8, 1978Date of Patent: June 24, 1980Assignee: Kabushiki Kaisha Morita SeisakushoInventors: Hiroshi Sugai, Shoji Nakayama