Patents by Inventor Shoji Yamane

Shoji Yamane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11136411
    Abstract: Provided is a humanized monoclonal antibody or an antibody fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: October 5, 2021
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Shoichi Naito, Hiroaki Aino, Etsuo Nakamura, Sunao Imai, Shoji Yamane
  • Patent number: 10745491
    Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: August 18, 2020
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Shoichi Naito, Junji Onoda, Tasuku Tsukamoto, Katsutoshi Yamada, Shoji Yamane, Yoshito Numata, Kazuhiko Maekawa, Tatsuya Takahashi
  • Publication number: 20200071424
    Abstract: Provided is a humanized monoclonal antibody or an antibody fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Application
    Filed: November 18, 2019
    Publication date: March 5, 2020
    Applicant: Shionogi & Co., Ltd.
    Inventors: Shoichi NAITO, Hiroaki AINO, Etsuo NAKAMURA, Sunao IMAI, Shoji YAMANE
  • Patent number: 10570215
    Abstract: Provided is a humanized monoclonal antibody or an antibody fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: February 25, 2020
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Shoichi Naito, Hiroaki Aino, Etsuo Nakamura, Sunao Imai, Shoji Yamane
  • Publication number: 20190211114
    Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Application
    Filed: January 11, 2019
    Publication date: July 11, 2019
    Applicant: SHIONOGI & CO., LTD.
    Inventors: Shoichi NAITO, Junji ONODA, Tasuku TSUKAMOTO, Katsutoshi YAMADA, Shoji YAMANE, Yoshito NUMATA, Kazuhiko MAEKAWA, Tatsuya TAKAHASHI
  • Patent number: 10239955
    Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: March 26, 2019
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Shoichi Naito, Junji Onoda, Tasuku Tsukamoto, Katsutoshi Yamada, Shoji Yamane, Yoshito Numata, Kazuhiko Maekawa, Tatsuya Takahashi
  • Publication number: 20170275378
    Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Application
    Filed: June 2, 2017
    Publication date: September 28, 2017
    Applicant: SHIONOGI & CO., LTD.
    Inventors: Shoichi NAITO, Junji ONODA, Tasuku TSUKAMOTO, Katsutoshi YAMADA, Shoji YAMANE, Yoshito NUMATA, Kazuhiko MAEKAWA, Tatsuya TAKAHASHI
  • Publication number: 20170260290
    Abstract: Provided is a humanized monoclonal antibody or an antibody fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Application
    Filed: March 10, 2017
    Publication date: September 14, 2017
    Applicant: Shionogi & Co., Ltd.
    Inventors: Shoichi NAITO, Hiroaki AINO, Etsuo NAKAMURA, Sunao IMAI, Shoji YAMANE
  • Patent number: 9701757
    Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: July 11, 2017
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Shoichi Naito, Junji Onoda, Tasuku Tsukamoto, Katsutoshi Yamada, Shoji Yamane, Yoshito Numata, Kazuhiko Maekawa, Tatsuya Takahashi
  • Patent number: 9296825
    Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits enzyme activity of EL and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: March 29, 2016
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Shoichi Naito, Junji Onoda, Tasuku Tsukamoto, Katsutoshi Yamada, Shoji Yamane, Yoshito Numata, Kazuhiko Maekawa, Tatsuya Takahashi, Yasuhiko Sato
  • Publication number: 20160009819
    Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Application
    Filed: March 12, 2014
    Publication date: January 14, 2016
    Applicant: SHIONOGI & CO., LTD.
    Inventors: Shoichi NAITO, Junji ONODA, Tasuku TSUKAMOTO, Katsutoshi YAMADA, Shoji YAMANE, Yoshito NUMATA, Kazuhiko MAEKAWA, Tatsuya TAKAHASHI
  • Patent number: 9222947
    Abstract: Provided are a monoclonal antibody capable of specifically recognizing a specific region of sAPP ? or a fragment of said antibody and an assay method and an assay kit using the same, in order to accurately assay sAPP? contained in a biological sample.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: December 29, 2015
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Tatsuya Takahashi, Junji Onoda, Yasunobu Yoshida, Shoji Yamane, Kouhei Nishitomi, Hidekuni Yamakawa, Akira Yamauchi, Atsushi Morita, Isao Fukuda
  • Publication number: 20150111231
    Abstract: Provided are a monoclonal antibody capable of specifically recognizing a specific region of sAPP ? or a fragment of said antibody and an assay method and an assay kit using the same, in order to accurately assay sAPP? contained in a biological sample.
    Type: Application
    Filed: February 1, 2013
    Publication date: April 23, 2015
    Inventors: Tatsuya Takahashi, Junji Onoda, Yasunobu Yoshida, Shoji Yamane, Kouhei Nishitomi, Hidekuni Yamakawa, Akira Yamauchi, Atsushi Morita, Isao Fukuda
  • Publication number: 20150025225
    Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits enzyme activity of EL and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.
    Type: Application
    Filed: October 11, 2012
    Publication date: January 22, 2015
    Inventors: Shoichi Naito, Junji Onoda, Tasuku Tsukamoto, Katsutoshi Yamada, Shoji Yamane, Yoshito Numata, Kazuhiko Maekawa, Tatsuya Takahashi, Yasuhiko Sato
  • Publication number: 20120237948
    Abstract: The present invention provides a novel monoclonal antibody that is specific for a C-terminal neoepitope of a collagen fragment and has substantially equal binding affinity whether proline contained in the neoepitope is in a non-hydroxylated form or in a hydroxylated form, and an immunoassay, a measurement method, a kit and the like using the antibody. The antibody allows for quantification of a collagen fragment generated by digestion of a biological sample with a collagenase present in the sample, regardless of the presence or absence of a hydroxylated form of proline in the neoepitope.
    Type: Application
    Filed: September 16, 2010
    Publication date: September 20, 2012
    Applicant: Shionogi & Co., Ltd.
    Inventors: Yoshito Numata, Akira Yamauchi, Junji Onoda, Shoji Yamane, Tomoko Maeda
  • Patent number: 6656302
    Abstract: To provide an epoxy resin composition suitable as a matrix resin for fiber reinforcement, and a yarn prepreg suitable in unwindability, excellent in higher processability due to drapability, high in the tensile strength of the epoxy resin composition after curing, and high in efficiency of the strength of reinforcing fibers. A yarn prepreg, satisfying the following formulae (1) to (3): 50≦Wf≦80  (1) 20,000≦F≦100,000  (2) F/8,000≦d≦F/2,400  (3) where Wf is the content by weight of the fiber bundle (%), F is the number of filaments in the fiber bundle and d is the width of the prepreg (mm).
    Type: Grant
    Filed: January 11, 2001
    Date of Patent: December 2, 2003
    Assignee: Toray Industries, Inc.
    Inventors: Hajime Kishi, Masazumi Tokunoh, Tetsuyuki Kyono, Fumiaki Noma, Toyokazu Minakuchi, Shoji Yamane
  • Publication number: 20020009581
    Abstract: To provide an epoxy resin composition suitable as a matrix resin for fiber reinforcement, and a yarn prepreg suitable in unwindability, excellent in higher processability due to drapability, high in the tensile strength of the epoxy resin composition after curing, and high in efficiency of the strength of reinforcing fibers.
    Type: Application
    Filed: January 11, 2001
    Publication date: January 24, 2002
    Inventors: Hajime Kishi, Masazumi Tokunoh, Tetsuyuki Kyono, Fumiaki Noma, Toyokazu Minakuchi, Shoji Yamane
  • Patent number: 6228474
    Abstract: To provide an epoxy resin composition suitable as a matrix resin for fiber reinforcement, and a yarn prepreg suitable in unwindability, excellent in higher processability due to drapability, high in the tensile strength of the epoxy resin composition after curing, and high in efficiency of the strength of reinforcing fibers. A yarn prepreg, satisfying the following formulae (1) to (3): 50≦Wf≦80  (1) 20,000≦F≦100,000  (2) F/8,000≦d≦F/2,400  (3) where Wf is the content by weight of the fiber bundle (%), F is the number of filaments in the fiber bundle and d is the width of the prepreg (mm).
    Type: Grant
    Filed: February 17, 1998
    Date of Patent: May 8, 2001
    Assignee: Toray Industries, Inc.
    Inventors: Hajime Kishi, Masazumi Tokunoh, Tetsuyuki Kyono, Fumiaki Noma, Toyokazu Minakuchi, Shoji Yamane
  • Patent number: 6117551
    Abstract: The present invention relates to a carbon fiber prepreg. The carbon fiber prepreg of the present invention is characterized in that a carbon fiber bundle comprising a plurality of continuous carbon filaments and having a hook drop value of 10 cm or more as the degree of fiber entanglement is impregnated with a base resin mainly composed of a thermosetting resin, and that particles of 150 .mu.m or less in particle size made of a thermoplastic resin account for 20 wt % or less based on the weight of the entire prepreg and distributed at a higher concentration in the surface zone than in the inside. The carbon fiber prepreg of the present invention is good in tackiness and less changing in tackiness with the lapse of time, and can form a composite with an excellent compression interlaminar shear strength (CILS) at high temperature after moisture absorption while maintaining good impact resistance.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: September 12, 2000
    Assignee: Toray Industries, Inc.
    Inventors: Hideo Nagata, Nobuyuki Odagiri, Takeshi Terashita, Hajime Kishi, Shoji Yamane
  • Patent number: 4917836
    Abstract: A process of producing carbon fibers, which comprises oxidizing polyacrylonitrile filaments having a tensile strength at 240.degree. C. of 0.3 g/d or higher and a tensile modulus at 240.degree. C. of 2.0 g/d or higher in an oxidizing atmosphere under a high tension of 0.2 g/d or higher, and carbonizing the oxidized filaments under a high tension.
    Type: Grant
    Filed: October 27, 1988
    Date of Patent: April 17, 1990
    Assignee: Toray Industries, Inc.
    Inventors: Shoji Yamane, Tomitake Higuchi, Katsumi Yamasaka