Abstract: Disclosed herein is related to a method for treating a symptom associated with senescence in a subject by administering to the subject with an effective amount of corylin and/or neobavaisoflavone, wherein the symptom associated with senescence is loss of muscle strength, muscle weakness, loss of motor coordination, loss of balance, skin wrinkle, or a poor blood biochemical parameter.

Abstract: A method for inhibiting mammalian TOR in a cell, comprising: providing a compound of formula (1): and incubating the cell with the compound. Also provided is a method for extending life span of a subject, comprising: providing the compound; and administering the compound to the subject. Yet also provided is a method for treating a mammalian TOR activation-caused disease in a subject, comprising: providing the compound; and administering the compound to the subject.

Abstract: A method for inhibiting mammalian TOR in a cell, comprising: providing a compound of formula (1): and incubating the cell with the compound. Also provided is a method for extending life span of a subject, comprising: providing the compound; and administering the compound to the subject. Yet also provided is a method for treating a mammalian TOR activation-caused disease in a subject, comprising: providing the compound; and administering the compound to the subject.

Abstract: This invention relates to compounds of Formula (I), (II), or (III) shown in the specification. These compounds can be used to treat hepatitis C virus infection.

Abstract: This invention relates to the compounds of formula (I) shown below. Each variable in formula (I) is defined in the specification. These compounds can be used to treat a kinesin Eg5 protein-mediated disorder.

Abstract: This invention relates to the compounds of formula (I) shown below. Each variable in formula (I) is defined in the specification. These compounds can be used to treat a kinesin Eg5 protein-mediated disorder.

Abstract: A motorized apparatus for towing a wheelchair includes a framework, a handle assembly, a motor driving assembly and a wheelchair connecting assembly. The framework includes a chassis. The handle assembly is adjustably mounted on the chassis. The motor driving assembly is mounted on the chassis and includes a wheel assembly with a single wheel rotatably mounted on the chassis, a combined clutch and brake assembly connected to the wheel assembly, a motor assembly connected to the combined clutch and brake assembly to drive the single wheel assembly through the combined clutch and brake assembly and a one-hand operated battery assembly coupled electrically to the motor assembly to drive the control unit and the motor assembly. The wheelchair connecting assembly interconnects the framework to a wheelchair. Consequently, the motorized apparatus will tow the wheelchair along a path, road and so on.

Abstract: A motorized apparatus for towing a wheelchair includes a framework, a handle assembly, a motor driving assembly and a wheelchair connecting assembly. The framework includes a chassis. The handle assembly is adjustably mounted on the chassis. The motor driving assembly is mounted on the chassis and includes a wheel assembly with a single wheel rotatably mounted on the chassis, a combined clutch and brake assembly connected to the wheel assembly, a motor assembly connected to the combined clutch and brake assembly to drive the single wheel assembly through the combined clutch and brake assembly and a one-hand operated battery assembly coupled electrically to the motor assembly to drive the control unit and the motor assembly. The wheelchair connecting assembly interconnects the framework to a wheelchair. Consequently, the motorized apparatus will tow the wheelchair along a path, road and so on.