Abstract: A freeze-dried product continuously manufactured by being dried while smoothly moving in a state of receiving a mechanical force in a freeze-drying apparatus 1. The freeze-drying apparatus 1 includes a freezing unit 2 for producing a frozen substance by spraying a raw material solution; and a drying unit 3 for drying the frozen substance. The drying unit 3 has a tubular shape and includes a tubular member 31 kept in a vacuum state, and a spiral wall or groove portion is formed on an inner wall of the tubular member 31 continuously in a longitudinal direction of the tubular member 31. A heat is transferred to the inner wall of the tubular member 31 and the spiral wall or groove portion. The tubular member 31 is configured to be rotated to transfer the freeze-dried product in the longitudinal direction of the tubular member 31 and sublimate or dry the freeze-dried product.

Abstract: A freeze-dried product continuously manufactured by being dried while smoothly moving in a state of receiving a mechanical force in a freeze-drying apparatus 1. The freeze-drying apparatus 1 includes a freezing unit 2 for producing a frozen substance by spraying a raw material solution; and a drying unit 3 for drying the frozen substance. The drying unit 3 has a tubular shape and includes a tubular member 31 kept in a vacuum state, and a spiral wall or groove portion is formed on an inner wall of the tubular member 31 continuously in a longitudinal direction of the tubular member 31. A heat is transferred to the inner wall of the tubular member 31 and the spiral wall or groove portion. The tubular member 31 is configured to be rotated to transfer the freeze-dried product in the longitudinal direction of the tubular member 31 and sublimate or dry the freeze-dried product.

Abstract: Provided are a vacuum freeze-drying apparatus and a method capable of continuously performing vacuum freeze-drying in a short time.

Abstract: Provided are a vacuum freeze-drying apparatus and a method capable of continuously performing vacuum freeze-drying in a short time.

Abstract: Provided is a vacuum freeze-drying apparatus 1, having a drying device 3 provided with an inlet portion and an outlet portion and comprising a tubular member 31 formed of a tubular shape, a temperature adjusting means 30a to 30j provided in a plurality of regions 40a to 40j in a direction from the inlet portion to the outlet portion in a peripheral portion of the tubular member for adjusting a temperature of the plurality of regions in an outer surface of the tubular member, a temperature control unit 8 for independently controlling the temperature adjusting means, and a rotating portion 7 for rotating the tubular member, wherein the tubular member has a spiral transfer means 31a for transferring the frozen substance entering from the inlet portion sequentially to locations corresponding to the plurality of regions in the tubular member to continuously sublimate and dry the frozen substance.

Abstract: Provided is a vacuum freeze-drying apparatus 1, having a drying device 3 provided with an inlet portion and an outlet portion and comprising a tubular member 31 formed of a tubular shape, a temperature adjusting means 30a to 30j provided in a plurality of regions 40a to 40j in a direction from the inlet portion to the outlet portion in a peripheral portion of the tubular member for adjusting a temperature of the plurality of regions in an outer surface of the tubular member, a temperature control unit 8 for independently controlling the temperature adjusting means, and a rotating portion 7 for rotating the tubular member, wherein the tubular member has a spiral transfer means 31a for transferring the frozen substance entering from the inlet portion sequentially to locations corresponding to the plurality of regions in the tubular member to continuously sublimate and dry the frozen substance.

Abstract: In a two-component-mixing prefilled syringe kit for preparing an injection solution by mixing a drug component in a syringe barrel and a liquid component in a container, when the injection needle pierced on the seal member of the container outlet is pulled out after preparation of the injection solution, a leak to the outside of the remaining liquid in the container is effectively prevented.

Abstract: Provided is a jelly for assisting in taking a drug that reduces a possibility of aspiration and makes it possible to deliver a drug efficiently to the digestive tract without remaining in the throat. Contained are a gelling agent including LM pectin, agar, and other thickening polysaccharide and a gelling promoter to gel and is taken mixed with the drug when taking the drug; LM pectin is contained 1-3 wt % relative to the jelly for assisting in taking the drug; the properties at 20±2° C. of a jelly produced by chopping the jelly for assisting in taking the drug are a hardness of 2000-6000 N/m2, adhesiveness of 200-500 J/m3, and cohesiveness of 0.2-0.6; and the water separation from the jelly 10 minutes after chopping the jelly for assisting in taking the drug is 3 wt % or less relative to the jelly for assisting in taking the drug.

Abstract: An orally disintegrable tablet, of the present invention, which comprises (i) fine granules having an average particle diameter of 400 ?m or less, which fine granules comprise a composition coated by an enteric coating layer, said composition having 10 weight % or more of an acid-labile physiologically active substance and (ii) an additive, has superior disintegrability or dissolution in the oral cavity so that it can be used for treatment or prevention of various diseases, as an orally disintegrable tablet capable of being administered to the aged or children and easily administered without water. Also, because the tablet of the present invention contains fine granules having the average particle diameter such that it will not impart roughness in mouth, it can be administered easily without discomfort at the administration.

Abstract: Provided is a jelly for assisting in taking a drug that reduces a possibility of aspiration and makes it possible to deliver a drug efficiently to the digestive tract without remaining in the throat. Contained are a gelling agent including LM pectin, agar, and other thickening polysaccharide and a gelling promoter to gel and is taken mixed with the drug when taking the drug; LM pectin is contained 1-3 wt % relative to the jelly for assisting in taking the drug; the properties at 20±2° C. of a jelly produced by chopping the jelly for assisting in taking the drug are a hardness of 2000-6000 N/m2, adhesiveness of 200-500 J/m3, and cohesiveness of 0.2-0.6; and the water separation from the jelly 10 minutes after chopping the jelly for assisting in taking the drug is 3 wt % or less relative to the jelly for assisting in taking the drug.

Abstract: To provide a medication storage cell that can be easily opened by a person who cannot dexterously move his or her fingertips. A small-medication storage cell (12) is provided with an accommodating section (20) and an interlocking piece (22). The accommodating section (20) has an outlet for a medication (100). The outlet (30) is formed using a sheet (60) provided with an interlocking piece, and a cover sheet (62). The interlocking piece (22) has a base section (40) and a tip end section (42). At least a part of the base section (40) is separated from the surface of the accommodating section (20). The tip end section (42) is fastened to the accommodating section (20) in a bent state so that the cover sheet (62) and the sheet (60) provided with an interlocking piece close the outlet (30).

Abstract: To provide a medication storage cell that can be easily opened by a person who cannot dexterously move his or her fingertips. A small-medication storage cell (12) is provided with an accommodating section (20) and an interlocking piece (22). The accommodating section (20) has an outlet for a medication (100). The outlet (30) is formed using a sheet (60) provided with an interlocking piece, and a cover sheet (62). The interlocking piece (22) has a base section (40) and a tip end section (42). At least a part of the base section (40) is separated from the surface of the accommodating section (20). The tip end section (42) is fastened to the accommodating section (20) in a bent state so that the cover sheet (62) and the sheet (60) provided with an interlocking piece close the outlet (30).

Abstract: A divided packet (10) has a packaging body (2), a drug (3), and a divided bag (4). The packaging body (2) seals in a swallowing aid substance (1). The drug (3) is disposed on the exterior of the packaging body (2). The divided bag (4) seals in the drug (3) and the packaging body (2) in which the swallowing aid substance (1) is sealed. The packaging body (2) and the drug (3) are sealed in the divided bag (4). Due to this configuration, using a simple method it is possible to provide the divided packet (10) with which the swallowing of the drug (3) can be aided.

Abstract: An orally disintegrable tablet, of the present invention, which comprises (i) fine granules having an average particle diameter of 400 ?m or less, which fine granules comprise a composition coated by an enteric coating layer, said composition having 10 weight % or more of an acid-labile physiologically active substance and (ii) an additive, has superior disintegrability or dissolution in the oral cavity so that it can be used for treatment or prevention of various diseases, as an orally disintegrable tablet capable of being administered to the aged or children and easily administered without water. Also, because the tablet of the present invention contains fine granules having the average particle diameter such that it will not impart roughness in mouth, it can be administered easily without discomfort at the administration.

Abstract: A container for an orally ingested pharmaceutical composition has, in a container body, a pharmaceutical composition chamber, a chamber for an auxiliary substance for the pharmaceutical composition chamber, and a chamber for the auxiliary substance for a cap. The container for an orally ingested pharmaceutical composition is provided with said cap in addition to a container body. An inter-chamber portion seals the pharmaceutical composition chamber from the chamber for the auxiliary substance for the chamber. A boundary portion seals the chamber for the cap auxiliary substance from the inside of the cap. By the inter-chamber portion and the boundary portion being bent, one end of the container body is removably inserted into the cap.

Abstract: In order to reduce the labor associated with the administration of a medication or the like to a patient via a tube, while ensuring that the medication can be administered with at least the same degree of safety and accuracy as in the past, a container for administering a medication is provided with a storage section and a discharge section. The storage section has an inlet. The container for administering a medication is further provided with a sealing part. The sealing part seals the boundary section between the storage section and the discharge section, and opens the boundary section when the storage part is subjected to a force of a prescribed magnitude or greater while a mixture is stored therein. The discharge section can be connected to a tube. In addition to the inlet, the storage section is also provided with an inlet opening/closing part.

Abstract: A material to be dried is frozen and is efficiently freeze-dried in a short time, thereby increasing production efficiency. A freeze-drying apparatus includes a vertical tube (2) having an inner circumferential surface formed with a frozen surface (2a), a liquid-supply device (5) for supplying a liquid material to be dried (47) onto the frozen surface (2a), a freezing device (10) arranged around the vertical tube (2) and intended for cooling the frozen surface (2a), a pressure-reduction device (12) which puts an interior area of the vertical tube (2) into a state of vacuum, and an internal heating device (41) in the vertical tube (2). The internal heating device (41) is arranged in the vertical tube (2) along a center axis thereof, and has an outer surface formed with a vertically long circular-cylindrical radiation surface (43).

Abstract: A container for an orally ingested pharmaceutical composition has, in a container body, a pharmaceutical composition chamber, a chamber for an auxiliary substance for the pharmaceutical composition chamber, and a chamber for the auxiliary substance for a cap. The container for an orally ingested pharmaceutical composition is provided with said cap in addition to a container body. An inter-chamber portion seals the pharmaceutical composition chamber from the chamber for the auxiliary substance for the chamber. A boundary portion seals the chamber for the cap auxiliary substance from the inside of the cap. By the inter-chamber portion and the boundary portion being bent, one end of the container body is removably inserted into the cap.

Abstract: Disclosed is a preparation for oral administration which can reduce the residual amount of a medicinal composition and facilitate the swallowing of the medicinal composition. A preparation for oral administration comprises an enclosing member that is formed of an edible film. A medicinal composition is enclosed in the enclosing member. The enclosing member has a wall part. The wall part is formed by rolling the edible film into a tubular shape. The wall part has a part where the edible film overlaps. The part where the edible film overlaps is formed by rolling a single edible film sheet.

Abstract: It is possible to easily swallow a pharmaceutical composition and to suppress the scattering thereof inside the mouth; furthermore, the pharmaceutical composition can be filled in easily. The pharmaceutical composition container 10 is equipped with a plurality of spaces 30 and 32. The portions 70 and 72 between two adjoining spaces are sealed. The portions 70 and 72 between two adjoining spaces open when force is applied from the outside of the pharmaceutical composition container 10. A swallowing-aid substance 40 is stored in the swallowing-aid substance storage chamber 30. An encapsulating item 42 is stored in the encapsulating-item storage chamber 32. The encapsulating item 42 contains the pharmaceutical composition 80. The sheet 20 is provided with a predetermined aperture part 60. The predetermined aperture part 60 is a portion where an aperture is to be formed. The aperture interconnects the outside of the pharmaceutical composition container 10 with the spaces 30 and 32.