Patents by Inventor Shuji TERAI

Shuji TERAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INDUCTION METHOD FOR MACROPHAGE, ANTI-INFLAMMATORY MACROPHAGE-INDUCING AGENT, AND PHARMACEUTICAL COMPOSITION
    Publication number: 20220062347
    Abstract: An induction method for a macrophage is provided, in which macrophages are cultured in the presence of exosomes produced from a mesenchymal stem cell to which interferon gamma has been added and are induced into anti-inflammatory macrophages. An anti-inflammatory macrophage-inducing agent includes exosomes produced from a mesenchymal stem cell to which interferon gamma has been added, as an active component. A pharmaceutical composition contains the inducing agent.
    Type: Application
    Filed: March 6, 2020
    Publication date: March 3, 2022
    Inventors: Shuji TERAI, Atsunori TSUCHIYA, Suguru TAKEUCHI
  • Method for evaluating mesenchymal stem cell activity, method for culturing mesenchymal stem cells, method for producing therapeutic agent for liver dysfunction, and therapeutic agent for liver dysfunction
    Patent number: 10744159
    Abstract: A method for evaluating the activity level of mesenchymal stem cells, and a method for culturing mesenchymal stem cells using the evaluation method in the field of culturing mesenchymal stem cells for regenerative medicine, and further, a method for producing a therapeutic agent for liver dysfunction and a therapeutic agent for liver dysfunction. This method for evaluating mesenchymal stem cell activity has an assay step for assaying the amount of adenylate kinase 4 (AK4) in the mesenchymal stem cells; and a determination step for determining the activity level of the mesenchymal stem cells from the assayed amount of adenylate kinase 4.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: August 18, 2020
    Assignees: YAMAGUCHI UNIVERSITY, SHIBUYA CORPORATION
    Inventors: Isao Sakaida, Shuji Terai, Taro Takami, Koichi Fujisawa, Naoki Yamamoto, Kenji Yoneda
  • Model of viscera, tissues, or organs
    Patent number: 10713973
    Abstract: Provided is a pseudo visceral model having a specific texture. A model of viscera, tissues, or organs comprising a foam layer containing a hydrogel.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: July 14, 2020
    Assignees: SUNARROW LTD, NIIGATA UNIVERSITY
    Inventors: Yutaka Kuwabara, Atsushi Ogawa, Ken-ichi Mizuno, Hiroki Sato, Shuji Terai
  • MODEL OF VISCERA, TISSUES, OR ORGANS
    Publication number: 20180357930
    Abstract: Provided is a pseudo visceral model having a specific texture. A model of viscera, tissues, or organs comprising a foam layer containing a hydrogel.
    Type: Application
    Filed: December 2, 2016
    Publication date: December 13, 2018
    Applicants: SUNARROW LTD, Niigata University
    Inventors: Yutaka Kuwabara, Atsushi Ogawa, Ken-ichi Mizuno, Hiroki Sato, Shuji Terai
  • METHOD FOR EVALUATING MESENCHYMAL STEM CELL ACTIVITY, METHOD FOR CULTURING MESENCHYMAL STEM CELLS, METHOD FOR PRODUCING THERAPEUTIC AGENT FOR LIVER DYSFUNCTION, AND THERAPEUTIC AGENT FOR LIVER DYSFUNCTION
    Publication number: 20170246211
    Abstract: The present invention relates to a method for evaluating the activity level of mesenchymal stem cells, and a method for culturing mesenchymal stem cells using the evaluation method in the field of culturing mesenchymal stem cells for regenerative medicine, and further, a method for producing a therapeutic agent for liver dysfunction and a therapeutic agent for liver dysfunction. This method for evaluating mesenchymal stem cell activity according to the present invention comprises an assay step for assaying the amount of adenylate kinase 4 (AK4) in the mesenchymal stem cells; and a determination step for determining the activity level of the mesenchymal stem cells from the assayed amount of adenylate kinase 4.
    Type: Application
    Filed: August 19, 2015
    Publication date: August 31, 2017
    Inventors: Isao SAKAIDA, Shuji TERAI, Taro TAKAMI, Koichi FUJISAWA, Naoki YAMAMOTO, Kenji YONEDA