Patents by Inventor Shuxin Li

Shuxin Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12016537
    Abstract: A sponge-based variable-stiffness support structure for natural orifice surgical instrument is to support the surgical instrument and includes: a variable-stiffness sponge pipeline connected with the natural orifice surgical instrument and configured to support the natural orifice surgical instrument in a natural orifice; a hydrophobic breathable film attached to an outer wall of the variable-stiffness sponge pipeline, and configured to isolate the variable-stiffness sponge pipeline from body fluid in the natural orifice; and a gas delivery assembly connected with the variable-stiffness sponge pipeline, and configured to inject high-pressure air or water vapor into a variable-stiffness sponge pipe of the variable-stiffness sponge pipeline; wherein the variable-stiffness sponge pipeline has a stiffness inversely proportional to content of the water vapor.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: June 25, 2024
    Assignee: Tianjin University
    Inventors: Shuxin Wang, Xuyang Ren, Guokai Zhang, Zufeng Shang, Jinhua Li
  • Patent number: 12012681
    Abstract: Disclosed is a method for preparing a fully-degradable non-woven fabric by spun-bonding, including: (S1) preparation of a poly(caprolactone-co-lactide acid) (P(CL-co-LA)); (S2) preparation of a copolymerized-modified poly(lactide acid) (PLA); and (S3) preparation of a full-degradable non-woven fabric using a spun-bond method. In this disclosure, the PLA is modified in gradient several times to prepare the full-degradable non-woven fabric in combination with an optimized spun-bonding method.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: June 18, 2024
    Assignees: China Yunhong Holdings Co., Ltd., Yunhong Environmental Technology Co., Ltd., Guozhong Xinghe Biomedical Technology Co., Ltd.
    Inventors: Jingren He, Yubao Li, Dong Wu, Shuxin Ye, Sijia Jiang, Rui Zhang
  • Patent number: 12011245
    Abstract: A surgical robot mechanism with single-port and multi-port minimally invasive surgery functions includes: a bracket; and a manipulator connected to the bracket, and supported by the bracket, the manipulator includes: a support arm movable along the bracket; a function conversion frame fixed on the support arm and configured for the surgical robot mechanism to switch between a single-port minimally invasive surgery mode and a multi-port minimally invasive surgery mode; a plurality of posture adjustment arm assemblies connected to the function conversion frame, each posture adjustment arm assembly configured to adjust a position and posture of a surgical tool connected thereto for performing a surgical operation.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: June 18, 2024
    Assignee: TIANJIN UNIVERSITY
    Inventors: Shuxin Wang, Zhenxuan Hu, Guokai Zhang, Dezhong Gao, Jianmin Li, Jinhua Li
  • Publication number: 20240159692
    Abstract: The present invention discloses a device and method for measuring the relative permeability of propped fractures in shale considering probability distribution, comprising a gas cylinder, a water pump, a booster pump, a rock slab holder, a differential pressure sensor, a directional X-ray source, an X-ray detector, an X-ray shielding box, a tee, a liquid meter, a gas meter, an electronic balance, and a vacuum pump; the inlet of rock slab holder is respectively connected with the gas cylinder and the water pump by the pipe, the outlet is connected with the liquid meter and the vacuum pump by the tee, and the differential pressure sensor is connected with both ends of the rock slab holder; the booster pump is connected with the rock slab holder by the pipe; the inlet of the gas meter is connected with the liquid meter, and the outlet is connected to the external atmosphere.
    Type: Application
    Filed: December 30, 2022
    Publication date: May 16, 2024
    Applicant: Southwest Petroleum University
    Inventors: Zhenglan LI, Yonggang DUAN, Mingqiang WEI, Quantang FANG, Le LUO, Keyi REN, Lei MENG, Shuxin LI, Zhihong NIE
  • Publication number: 20240158811
    Abstract: The present invention generally relates to engineered adeno-associated viral (AAV) vectors capable of traversing the blood-brain barrier and transducing specific neural cells with high efficiency. The present invention also relates to methods of producing engineered AAV vectors and treating diseases and disorders associated with neural cell damage and degeneration.
    Type: Application
    Filed: March 11, 2022
    Publication date: May 16, 2024
    Inventor: SHUXIN Li
  • Publication number: 20230141101
    Abstract: A class of PDE4 inhibitor compounds, and an isomer, solvate, deuterated derivative, or pharmaceutically acceptable salt thereof. A drug that comprises the compound, isomer, solvate, deuterated derivative, and pharmaceutically acceptable salt thereof, and a use thereof in preparing a drug for treating diseases related to PDE4 inhibition, such as autoimmune diseases and cancer.
    Type: Application
    Filed: February 22, 2021
    Publication date: May 11, 2023
    Applicant: Suzhou Longbotai Pharmaceuticals Co., Ltd.
    Inventors: Shuxin Li, Hengying Yang, Sheng Kuang, Sifan She, Kuiwang Wu, Shiwei Li
  • Patent number: 11513051
    Abstract: The present invention discloses a shale stress sensitivity testing device and method. The testing device comprises a support table. The left and right ends of the upper surface of the support table are respectively provided with a left side plate and a right side plate. The top of the left and right side plates are connected with the left and right ends of the top plate. The chucks of the clamps are capable of reciprocating motion in the horizontal direction and circular motion in the front-rear direction. The present invention can change the intensity and direction of the effective stress of the rock sample, and determine the permeability of the rock sample under different effective stresses, thus enabling comprehensive testing of the stress sensitivity of shale in different directions and enhancing the accuracy of shale stress sensitivity testing.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: November 29, 2022
    Assignee: Southwest Petroleum University
    Inventors: Mingqiang Wei, Yonggang Duan, Quantang Fang, Zhenglan Li, Le Luo, Keyi Ren, Xin Wang, Shuxin Li, Zhihong Nie
  • Patent number: 11414413
    Abstract: Disclosed are a heterocyclic derivative as a JAK inhibitor, and salts thereof, wherein the definitions of (II), (III) and R are described in detail in the specification. In addition, also disclosed are a medicine including the compound and salts thereof as an active ingredient, and the use thereof in the preparation of a medicine for treating JAK-related target diseases, such as immune system diseases, rheumatoid arthritis and tumors.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: August 16, 2022
    Assignee: Suzhou Longbiotech Pharmaceuticals Co., Ltd.
    Inventors: Hengying Yang, Sheng Kuang, Shiwei Li, Kuiwang Wu, Shuxin Li
  • Patent number: 11279699
    Abstract: Disclosed are a compound as a selective JAK inhibitor, and an isomer, a solvate or a pharmaceutically acceptable salt thereof, wherein: the definitions of (A), R, R1 and n are described in detail in the specification. In addition, also disclosed are a medicament including the compound and salts thereof as an active ingredient, and the use thereof in the preparation of a medicament for treating JAK-related target diseases, such as immune system diseases, rheumatoid arthritis and tumors.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: March 22, 2022
    Assignee: Suzhou Longbiotech Pharmaceuticals Co., Ltd.
    Inventors: Hengying Yang, Sheng Kuang, Shiwei Li, Kuiwang Wu, Shuxin Li
  • Patent number: 10680839
    Abstract: Methods and apparatus for transmitting data is disclosed. Data to be transmitted is segmented into data packets. The segmented data packets are duplicated into multiple groups of data packets, which are then transmitted from a device at a transmitting end to a device at a receiving end using multiple transmission protocols in parallel. Each of a set of duplicated data packets is thus transmitted by one of the multiple transmission protocols. The data packet among each of set of duplicated data packets that is first received by the device at the receiving end is retained and other received data packets of the set of duplicated data packets are discarded. The disclosed methods and apparatus thus combine benefits of different transmission protocols. For example, the disclosed methods and apparatus help achieve both transmission integrity and timing.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: June 9, 2020
    Assignee: Tencent Technology (Shenzhen) Company Limited
    Inventors: Shuxin Li, Yingkun Xi
  • Patent number: 10011638
    Abstract: The presently disclosed subject matter relates to antagonists of PTEN and methods of using the same. In particular, the presently disclosed subject matter provides for PTEN antagonist peptides for use in treating central nervous system disorders. In an exemplary embodiment, the presently disclosed subject matter provides methods for promoting nerve fiber growth in a subject by administering to the subject a therapeutically effective amount of a PTEN antagonist peptide.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: July 3, 2018
    Assignee: Shriners Hospitals for Children
    Inventor: Shuxin Li
  • Publication number: 20170373864
    Abstract: Methods and apparatus for transmitting data is disclosed. Data to be transmitted is segmented into data packets. The segmented data packets are duplicated into multiple groups of data packets, which are then transmitted from a device at a transmitting end to a device at a receiving end using multiple transmission protocols in parallel. Each of a set of duplicated data packets is thus transmitted by one of the multiple transmission protocols. The data packet among each of set of duplicated data packets that is first received by the device at the receiving end is retained and other received data packets of the set of duplicated data packets are discarded. The disclosed methods and apparatus thus combine benefits of different transmission protocols. For example, the disclosed methods and apparatus help achieve both transmission integrity and timing.
    Type: Application
    Filed: August 22, 2017
    Publication date: December 28, 2017
    Applicant: Tencent Technology (Shenzhen) Company Limited
    Inventors: Shuxin Li, Yingkun Xi
  • Publication number: 20160311857
    Abstract: The presently disclosed subject matter relates to antagonists of PTEN and methods of using the same. In particular, the presently disclosed subject matter provides for PTEN antagonist peptides for use in treating central nervous system disorders. In an exemplary embodiment, the presently disclosed subject matter provides methods for promoting nerve fiber growth in a subject by administering to the subject a therapeutically effective amount of a PTEN antagonist peptide.
    Type: Application
    Filed: July 7, 2016
    Publication date: October 27, 2016
    Inventor: SHUXIN LI
  • Publication number: 20130184746
    Abstract: An inflation-deflation device for tourniquet comprising: a barrel (11) and a plunger (12) fitting tightly within the barrel (11). A connecting rod (13) is fixed at one end of the plunger (12). The barrel (11) is fixedly connected at its bottom to a short tube (10). The short tube (10) is connected to the interior space of the barrel (11). The connecting rod (13) having a cruciform cross-section structure, a baffle (16) is perpendicularly fixed to the two sides opposite each other from the central axis of the structure. Connected on the barrel (11) is a clasp (15), the clasp (15) is fixedly connected to the barrel (11) and extends into the interior surface of the barrel (11). The inflation-deflation device has a distinctively designed inflation hole connection tip, to prevent confusion with a standard Luer connection of an ordinary liquid syringe, and also has a distinctively designed deflation limit, to control effectively the volume of gas discharged in a single deflation, and to prevent mishandling.
    Type: Application
    Filed: July 14, 2011
    Publication date: July 18, 2013
    Applicant: LEPU MEDICAL TECHNOLOGY (BEIJING) CO., LTD.
    Inventors: Wanbing Liu, Shuxin Li
  • Publication number: 20120158212
    Abstract: The present invention provides a intelligent data center based on a service platform for vehicle-mounted devices, including: a static data storage unit, adapted for storing static data relating to a vehicle-mounted device; a static data processing unit, adapted for processing the static data stored in the static data storage unit; a dynamic data storage unit, adapted for storing dynamic data which are relating to the vehicle-mounted device and acquired by the service platform for vehicle-mounted devices; and a data analysis unit, adapted for analyzing the static data and the dynamic data. The intelligent data center can provide a wide variety of services for the vehicle-mounted device through the service platform.
    Type: Application
    Filed: December 27, 2010
    Publication date: June 21, 2012
    Applicants: Shanghai Pateo Internet Technology Service Co., Ltd., Shanghai Pateo Electronic Equipment Manufacturing Co., Ltd.
    Inventors: Yilun Ying, Liang Huo, Yu Jiang, Jun Zhu, Shuxin Li, Yong Gao, Dawei Zhu, Yehui Zhang
  • Publication number: 20070219220
    Abstract: The present invention disclosed the pyrazolopyrimidinethione derivatives, salts and solvates thereof, preparation methods and use thereof. The pyrazolopyrimidinethione derivatives according to the present invention possess the structure of general formula I, wherein, R1, R2, R3, and R4 represent alkyl, alkenyl, or aryl; R5 represents hydrogen, alkyl, alkenyl, alkoxy, cycloalkyloxy, aryl, or alkylacyl; and R6 represents hydrogen, alkyl, alkenyl, cycloalkyloxy, or alkylacyl. The pharmaceuticals containing the compound of the present invention and used for the treatment of impotence and sexlessness have the advantages of high selectivity over PDE V, long action time, and less side reactions, and the pharmaceuticals will arouse no side reactions of blood pressure decreasing and heart rate increasing, and it has broad market propect.
    Type: Application
    Filed: November 18, 2004
    Publication date: September 20, 2007
    Inventors: Shuxin Li, Jianping Ren, Yanjin Zhao, Qiujun Lv, Jinhua Guo
  • Patent number: 7034979
    Abstract: An optical device for processing an optical signal includes a crystal wedge, a polarization modulator, and a reflective element. The crystal wedge spatially separates an input optical signal into a first beam component having a first polarization state and a second beam component having a second polarization state. The crystal wedge has an optical axis arranged at an optical axis angle such that the first beam component and the second beam component converge. The polarization modulator changes the polarization state of the first beam component and the polarization state of the second beam component in response to a control signal. The reflective element reflects the first beam component and the second beam component such that the crystal wedge spatially recombines a portion of the first beam component having the second polarization state with a portion of the second beam component having the first polarization state to form an output optical signal.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: April 25, 2006
    Assignee: EZConn Corporation
    Inventors: Wei Feng, Chongchang Mao, Tirun Lin, Shuxin Li, Minchun Li, Ming Xu, Tizhi Huang
  • Publication number: 20030030881
    Abstract: An optical device comprises a first birefringent crystal having a first length, a second birefringent crystal having a second length, and a dynamic polarization rotator. An optical signal propagating through the first and second birefringent crystals has an effective optical path length based, at least in part, upon the first length of the first birefringent crystal and the second length of the second birefringent crystal. The dynamic polarization rotator adjusts the effective optical path length of the optical signal in response to a control signal.
    Type: Application
    Filed: August 3, 2001
    Publication date: February 13, 2003
    Applicant: Chorum Technologies LP
    Inventors: Tiejun Xia, Chi-Hao Cheng, Shuxin Li, Jian-Yu Liu, Kuang-Yi Wu
  • Patent number: 6515786
    Abstract: An optical device comprises a first birefringent crystal having a first length, a second birefringent crystal having a second length, and a dynamic polarization rotator. An optical signal propagating through the first and second birefringent crystals has an effective optical path length based, at least in part, upon the first length of the first birefringent crystal and the second length of the second birefringent crystal. The dynamic polarization rotator adjusts the effective optical path length of the optical signal in response to a control signal.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: February 4, 2003
    Assignee: Chorum Technologies LP
    Inventors: Tiejun Xia, Chi-Hao Cheng, Shuxin Li, Jian-Yu Liu, Kuang-Yi Wu