Abstract: This invention relates to certain sugar esters of phytosterols of formula (I).

Abstract: This invention relates to certain skin and hair care agents of formula (I), derived from natural amino acids and peptides. These agents provide multi-functional treatment of enzyme-related topical problems, for example, darkened skin including age spots, circles around eyes and stretch marks; skin conditions related to acne including excess facial oil and facial pore size; premature hair aging including hair loss and graying; inflammation including intra-cellular and extra-cellular inflammation; skin aging including wrinkles and fine lines; loss of collagen including thinning skin and loss of skin pliability; malfunction of tyrosinase group of enzymes; malfunction of matrix metalloprotease group of enzymes; and combinations thereof: Wherein, R, R?, and R?=any substituent(s); and M=H, Li, Na, K, Ca, Mg, Zn, Mn, Cu, Fe, Co, Mo, V, Cr, Ammonium, Alkyl ammonium, and Nitrogen Heterocyclic ammonium.

Abstract: This invention relates to esters of ascorbic acid with natural sugar lactones [formula (I)], which are useful for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, nail or skin requiring cleansers, conditioning or treatment, and hair or scalp requiring shampooing or conditioning, and combinations thereof;

Abstract: The present invention discloses cosmetic transparent hair removal (depilatory) compositions that: (1) Are transparent in appearance, (2) Can be made in cold wax or hot wax forms, (3) Manufactured at much less than 80 ° C., (4) Three-dimensional particles of visually attractive compositions can be added, (5) Bind more strongly with hair and less strongly with skin, (6) Can be applied either directly on the skin or applied on a piece of fabric, plastic, or paper first, which is then applied to skin for hair removal, and (7) Require minimal clean-up.

Abstract: This invention relates to certain complexes of ascorbic acid and its derivatives with certain aryl alkyl ketones; said complexes having being formed via a kinetically-controlled process, and having general chemical formula (I) in FIG. 1. Said complexes can be in their various optically active or racemic forms. This invention also relates to a method of treatment of skin condition, including dark skin, age spots, acne, inflammation, loss of cellular antioxidants, collagen loss with aging, loss of skin pliability, loss of skin suppleness, skin wrinkles, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, photo-damage, and combinations thereof; [FIG. 1].

Abstract: The present invention relates to a topical method of treatment for dysfunction of certain dermal enzymes, and the treatment of skin condition or disorder caused by said dysfunction. The said method of treatment consists of (i) an extra-cellular, matrix metalloprotease regulating agent, and (ii) an intra-cellular ubiquitin—proteasome regulating agent, and (iii) an epidermal melanocyte-regulating agent; and, wherein, said extra-cellular agent, said intracellular agent, and said epidermal agent can, surprisingly and unexpectedly, be a single multi-function compound having chemical formula (I).

Abstract: This invention relates to Schiff's bases derived from amino acids and hydroxyaryl alkyl ketones, or a plant extract containing the same, having general chemical structure in FIG. 1 for topical application. This invention also relates to certain metal complex of said Schiff's bases, which have a crown-like appearance in their three-dimensional chemical structure, as in FIG. 2. The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase, Phenylalanine Transaminase, Tyrosinase, various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase. These are further suitable for multifunctional topical methods for skin whitening, skin wrinkles reduction, skin antiaging, collagen synthesis, acne control, hair loss prevention, hair graying control, and facial oil control.

Abstract: The present invention discloses a method of treating skin conditions that include acne, skin wrinkles, age spots, pimples, scars, skin rash including diaper rash, dry skin, scalp dandruff, scalp dry skin, darkened skin, skin discoloration, broken skin, chafed skin, sunburn, skin damage from UV, skin irritation, body odor, or a combination thereof, via topical application of certain clathrates of zinc zeolite with non-antibiotic organic agents.

Abstract: The present invention provides a comprehensive solution to the problems associated with natural topical aging via the incorporation of: (i) An Extra-cellular antioxidant or Free-radical neutralizing composition, and (ii) An Intra-cellular antioxidant or Free-radical neutralizing composition, and (iii) An Anti-inflammatory composition, and (iv) A collagen or fibrin boosting composition. It is preferred to also have the above incorporated in a suitable carrier base or topical delivery system for skin, nail, and hair beneficial applications.

Abstract: The present invention provides a complementary three-step dermabrasion system that provides treatment for skin conditions such as acne scars, wound scars, and other visually unappealing skin disfigurements, which constitutes the following, (1) Dermal Resurfacing with an adhesive composition, (2) Dermal Polishing with a polishing composition, and (3) Dermal Regeneration with a collagen-building and cell-proliferative composition.

Abstract: This invention relates to a novel ion-pair delivery system useful for gender and ethnic background selective hair care and nail care applications in which an electron donor composition and an electron acceptor composition, or a proton donor composition and a proton acceptor composition, or an anionic and a cationic composition, are combined synergistically. The bioavailability, deposition, functional performance, and consumer aesthetics of the compositions thus combined in such ion-pairs are enhanced synergistically. Hair care compositions, such as shampoo, conditioner, hair lotion, hair oil, hair gel, hair sheen, hair rinse, hair balm, hair wax, hair spray, and such, and nail care compositions, such as nail enamel, nail creams, nail serums, nail lacquers, nail spray, and nail polish, and such, can thus be obtained with synergistically enhanced performance.

Abstract: This invention relates to a novel ion-pair delivery system useful for cosmetic, pharmaceutical, and topical nutraceutical applications in which the functional performance and consumer aesthetics of an electron donor composition and an electron acceptor composition, or a proton donor composition and a proton acceptor composition, are synergistically enhanced when such compositions are combined in an ion-pair mode. During ion-pair bonding process, the electron donor composition or the proton acceptor composition become positively charged and the electron acceptor composition or proton donor composition become negatively charged and thus bind together in an ionic manner. Such ion-pair compositions release their electronically bound components in their original state when such compositions are absorbed into skin and reach physiological pH conditions.

Abstract: The present invention discloses a novel ion-pair delivery system based mask compositions for face, hair, skin, and body applications. These compositions come off from the site of their application essentially in one piece with the appearance, for example, of a piece of sea-weed or a continuous film. These mask compositions are suitable for a variety of delivery system methods, such as peel-off mask, moisturizing mask, exfoliating mask, prosthetic mask, soaking mask, depilatory mask, rub-off mask, two-phase mask, two-compartment mask, heat-releasing mask, and such. These mask compositions are made from the biopolymer based films that are cross-linked with divalent or trivalent metal cations. During the cross-linking process, such divalent and trivalent metal cations may also act as release agents for other face, hair, skin, and body beneficial compositions in their enhanced bioavailable forms by an ion-pair activation mechanism.

Abstract: The present invention discloses the utilization of zeolites for controlled-release of cosmetic and pharmaceutical compositions by nano-diffusion technology. The treatment and protection of skin surface requires that certain compositions be delivered to the skin surface and allowed to remain on the skin surface for as long as possible before such ingredients are absorbed into deeper layers of skin and carried into the bloodstream. Zeolites do not absorb into the skin, which is useful for topical delivery of cosmetic and pharmaceutical compositions, for example antiaging, anti-wrinkle, antioxidants, skin whitening, acne treatment, rosacea treatment, sun screens, UV blocks, anesthetics, skin soothers, anti-irritants, anti-inflammatory agents, vitamins, hormones, and such that are electronically attached to the outer surfaces of such zeolites and are released to the outer surface of skin by a diffusion-controlled thermodynamic process.

Abstract: The present invention discloses cosmetic or topical pharmaceutical compositions for body slimming, firming, cellulite reduction, fat-reduction, and obesity control benefits that can be selective and specific for external body parts and organs such as face, chin, cheeks, arms, “love handles” in abdomen area, eye lids and eye zone, neck, breasts, thighs, and hips. These compositions include a synergistic, bioavailability-enhanced ion-pair combination of Hydroxycitric acid or Hydroxycitric acid derivatives with certain organic bases such as Niacinamide, Niacin, Pyridoxine, Aminophylline, Caffeine, Carnitine, Creatine, Chitosan, Allantoin, Glucosamine, Phaseolamine, Chromium Picolinate, Theobromine, Theophylline, and such.

Abstract: The present invention discloses cosmetic transparent hair removal (depilatory) compositions that: (1) Are transparent in appearance, (2) Can be made in cold wax or hot wax forms, (3) Manufactured at much less than 80 ° C., (4) Three-dimensional particles of visually attractive compositions can be added, (5) Bind more strongly with hair and less strongly with skin, (6) Can be applied either directly on the skin or applied on a piece of fabric, plastic, or paper first, which is then applied to skin for hair removal, and (7) Require minimal clean-up.

Abstract: I have discovered cosmetic cold-wax hair removal (depilatory) compositions suitable for site-specific face or body applications with the following attributes: (1) A pre-heating or microwave step is not necessary, (2) Complete hair removal is achieved in a single application on a specific site or area, (3), No (or minimal) skin irritation is experienced, (4) Bond to hair preferentially, and not to skin, (5) Provide lubricity and emolliency to skin, (6) Can be applied either directly on the skin or, preferably, on a piece of precut fabric, plastic or paper, which is then applied to specific site where hair removal is desired. Alternatively, dispensing applicators can also be used that can be filled for delivery at the specific site where depilation is desired.

Abstract: The present invention relates to boosting of the skin whitening benefits of commonly used tyrosinase inhibitors, tyrosinase competitors, and melanin and other color bodies' reducing agents. The activity of such compositions can be synergistically enhanced by the inclusion of at least one antioxidant composition. This synergistic benefit is further increased if a UV-inhibitor or UV-absorber is also included in such compositions. This is both unexpected and surprising because most such tyrosinase inhibitors, tyrosinase competitors, or melanin reducing agents are also known to possess antioxidant and UV-absorbing properties. Thus, the skin whitening benefits are synergistically increased by combining at least one of the following; (i) a tyrosinase inhibiting agent, or (ii) a tyrosinase competing agent, or (iii) a melanin reducing agent, or (iv) combinations thereof; with at least one antioxidant composition.

Abstract: I have discovered cosmetic mask compositions suitable for face, neck, chin or body applications. These compositions synergistically combine at least one skin beneficial cosmetic or drug composition with at least one composition to promote excess fat reduction, cellulite control, or muscle toning benefits. The mask composition also contains at least one binder composition that binds with other beneficial ingredients by electrostatic, atomic, or ionic charges to synergistically enhance their topical site-specific benefits. These mask compositions are suitable for a variety of delivery system methods that include peel-off mask, leave-in mask, moisturizing mask, exfoliating mask, prosthetic mask, soaking mask, depilatory mask, foaming mask, rinse-off mask, sloughing mask, rub-off mask, two-phase mask, dual-chamber mask, and self-heating (heat releasing) mask.

Abstract: The present invention relates to acne and rosacea compositions by a six-prong synergistic combination treatment strategy that includes (1) control of excess sebum production, (2) control of undesirable bacteria or mites, (3) control of inflammation, (4) enhanced desquamation of follicular infundibulum cells, (5) reduction of irritation from anti-acne or rosacea compositions themselves, and (6) enhancement of the topical bioavailability of anti-acne and rosacea compositions. This is achieved by a synergistic combination of commonly utilized topical anti-acne and rosacea ingredients with a topical bioavailability enhancement composition, which results in enhanced anti-acne and rosacea action from such ingredients. Moreover, additional inclusion of an anti-inflammatory composition, and also a vascular micro-circulation enhancement composition, further results in synergistic superior anti-acne and rosacea benefits from such compositions.