Patents by Inventor Siao-Kun Welch

Siao-Kun Welch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cellular permissivity factor for viruses and uses thereof
    Patent number: 9102912
    Abstract: The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: August 11, 2015
    Assignee: Zoetis Services LLC
    Inventors: Jay Gregory Calvert, Shelly Shields, David E. Slade, Siao-Kun Welch
  • Cellular Permissivity Factor for Viruses and Uses Thereof
    Publication number: 20140141492
    Abstract: The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
    Type: Application
    Filed: July 12, 2013
    Publication date: May 22, 2014
    Inventors: JAY GREGORY CALVERT, SHELLY SHIELDS, DAVID E. SLADE, SIAO-KUN WELCH
  • Cellular permissivity factor for viruses and uses thereof
    Patent number: 8486685
    Abstract: The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
    Type: Grant
    Filed: September 29, 2011
    Date of Patent: July 16, 2013
    Assignee: Zoetis P&U LLC
    Inventors: Jay Gregory Calvert, Shelly Shields, David E Slade, Siao-Kun Welch
  • N protein mutants of porcine reproductive and respiratory syndrome virus
    Patent number: 8128937
    Abstract: The present invention provides a genetically modified PRRS virus, methods to make it and related polypeptides, polynucleotides and various components. Vaccines comprising the genetically modified virus and polynucleotides are also provided.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: March 6, 2012
    Assignee: Pfizer Inc.
    Inventors: Dongwan Yoo, Changhee Lee, Jay Gregory Calvert, Siao-Kun Welch
  • Cellular Permissivity Factor for Viruses and Uses Thereof
    Publication number: 20120015425
    Abstract: The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
    Type: Application
    Filed: September 29, 2011
    Publication date: January 19, 2012
    Applicant: PHARMACIA AND UP JOHN COMPANY, LLC
    Inventors: Jay Gregory Calvert, Shelly Shields, David E. Slade, Siao-Kun Welch
  • Cellular permissivity factor for viruses and uses thereof
    Patent number: 8058050
    Abstract: The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: November 15, 2011
    Assignee: Pharmacia and Upjohn Company LLC
    Inventors: Jay Gregory Calvert, Shelly Shields, David E Slade, Siao-Kun Welch
  • Cellular Permissivity Factor for Viruses and Uses Thereof
    Publication number: 20100273238
    Abstract: The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
    Type: Application
    Filed: May 6, 2010
    Publication date: October 28, 2010
    Applicant: PHARMACIA & UPJOHN COMPANY, LLC
    Inventors: JAY GREGORY CALVERT, SHELLY SHIELDS, DAVID E. SLADE, SIAO-KUN WELCH
  • Cellular permissivity factor for viruses and uses thereof
    Patent number: 7754464
    Abstract: The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: July 13, 2010
    Assignee: Pharmacia and Upjohn Company, LLC
    Inventors: Jay Gregory Calvert, Shelly Shields, David E Slade, Siao-Kun Welch
  • N Protein Muants of Porcine Reproductive and Respiratory Syndrome Virus
    Publication number: 20100136051
    Abstract: The present invention provides a genetically modified PRRS virus, methods to make it and related polypeptides, polynucleotides and various components. Vaccines comprising the genetically modified virus and polynucleotides are also provided.
    Type: Application
    Filed: November 3, 2009
    Publication date: June 3, 2010
    Inventors: Dongwan Yoo, Changhee Lee, Jay Gregory Calvert, Siao-Kun Welch
  • N protein mutants of porcine reproductive and respiratory syndrome virus
    Publication number: 20090226486
    Abstract: The present invention provides a genetically modified PRRS virus, methods to make it and related polypeptides, polynucleotides and various components. Vaccines comprising the genetically modified virus and polynucleotides are also provided.
    Type: Application
    Filed: March 30, 2009
    Publication date: September 10, 2009
    Inventors: Dongwan Yoo, Changhee Lee, Jay Gregory Calvert, Siao-Kun Welch
  • N protein mutants of porcine reproductive and respiratory syndrome virus
    Patent number: 7544362
    Abstract: The present invention provides a genetically modified PRRS virus, methods to make it and related polypeptides, polynucleotides and various components. Vaccines comprising the genetically modified virus and polynucleotides are also provided.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: June 9, 2009
    Assignee: Pfizer Inc.
    Inventors: Dongwan Yoo, Changhee Lee, Jay Gregory Calvert, Siao-Kun Welch
  • N PROTEIN MUTANTS OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS
    Publication number: 20090130143
    Abstract: The present invention provides a genetically modified PRRS virus, methods to make it and related polypeptides, polynucleotides and various components. Vaccines comprising the genetically modified virus and polynucleotides are also provided.
    Type: Application
    Filed: February 22, 2006
    Publication date: May 21, 2009
    Inventors: Dongwan Yoo, Changhee Lee, Jay Gregory Calvert, Siao-Kun Welch
  • Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
    Publication number: 20070116720
    Abstract: The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, wherein the polynucleotide molecule lacks at least one detectable antigenic epitope of North American PRRS virus. The invention also provides vaccines comprising genetically modified North American PRRS virus, RNA molecules, plasmids and viral vectors comprising the isolated polynucleotide molecules. Also provided are isolated polynucleotide molecules further comprising at least one nucleotide sequence that encodes a detectable heterologous antigenic epitope, and vaccines comprising North American PRRS virus, RNA molecules, plasmids and viral vectors comprising such isolated polynucleotide molecules.
    Type: Application
    Filed: October 25, 2006
    Publication date: May 24, 2007
    Inventors: Jay Calvert, Michael Sheppard, Siao-Kun Welch, Raymond Rowland, Dal-Young Kim
  • Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof
    Publication number: 20060183113
    Abstract: The invention provides isolated polynucleotide molecules, including plasmids; viral vectors; and transfected host cells that comprise a DNA sequence encoding an infectious RNA sequence encoding a North American PRRS virus; and also North American PRRS viruses encoded thereby. The invention further provides isolated infectious RNA molecules encoding a North American PRRS virus. The invention also provides isolated polynucleotide molecules, infectious RNA molecules, viral vectors, and transfected host cells encoding genetically-modified North American PRRS viruses; and genetically-modified North American PRRS viruses encoded thereby. The invention also provides vaccines comprising such plasmids, RNA molecules, viral vectors, and North American PRRS viruses, and methods of using these vaccines in swine and in other animals. Also provided are isolated polynucleotide molecules, viral vectors, and transfected host cells that comprise a nucleotide sequence encoding a peptide of a North American PRRS virus.
    Type: Application
    Filed: March 1, 2006
    Publication date: August 17, 2006
    Inventors: Jay Calvert, Michael Sheppard, Siao-Kun Welch, Raymond Rowland, Dal-Young Kim
  • Cellular permissivity factor for viruses and uses thereof
    Publication number: 20050271685
    Abstract: The present invention provides methods and compositions related to the generation of host cells permissive for virus growth, particularly Porcine Reproductive and Respiratory Syndrome (PRRS) virus.
    Type: Application
    Filed: April 25, 2005
    Publication date: December 8, 2005
    Applicant: Pharmacia and Upjohn Company, LLC
    Inventors: Jay Calvert, Shelly Shields, David Slade, Siao-Kun Welch
  • Safe mutant viral vaccines
    Publication number: 20050053621
    Abstract: The present invention provides safe vaccines and methods of preparing such vaccines. The vaccines of the present invention contain at least two live mutant viruses of the same family or nucleic acid molecules encoding such viruses, wherein each of the two viruses or the encoding nucleic adds contains a mutation that confers a desirable phenotype and the mutations in the viruses reside in the same genomic site such that the mutant viruses cannot recombine with each other to eliminate the mutations.
    Type: Application
    Filed: July 16, 2004
    Publication date: March 10, 2005
    Inventors: Siao-Kun Welch, Jay Calvert, Michael O'Hara, Xuemei Cao