Patents by Inventor Simon P. Robinson

Simon P. Robinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPID-ENCAPSULATED GAS MICROSPHERE COMPOSITIONS AND RELATED METHODS
    Publication number: 20200384132
    Abstract: The invention provides, inter alia, improved lipid formulations used to generate lipid-encapsulated gas microspheres, and methods of their use.
    Type: Application
    Filed: February 3, 2020
    Publication date: December 10, 2020
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, David C. Onthank, Nhung Tuyet Nguyen
  • COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS
    Publication number: 20200230264
    Abstract: The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.
    Type: Application
    Filed: October 25, 2019
    Publication date: July 23, 2020
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Richard R. Cesati, Heike S. Radeke, Suresh K. Pandey, Ajay Purohit, Simon P. Robinson
  • METHODS AND DEVICES FOR PREPARATION OF ULTRASOUND CONTRAST AGENTS
    Publication number: 20200171177
    Abstract: Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.
    Type: Application
    Filed: February 3, 2020
    Publication date: June 4, 2020
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Carol Walker, David C. Onthank, Joel Lazewatsky, Nhung Tuyet Nguyen
  • Methods and devices for preparation of ultrasound contrast agents
    Patent number: 10588988
    Abstract: Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: March 17, 2020
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Carol Walker, David C. Onthank, Joel Lazewatsky, Nhung Tuyet Nguyen
  • Methods for making ultrasound contrast agents
    Patent number: 10583208
    Abstract: Provided herein are improved methods for preparing phospholipid formulations including phospholipid UCA formulations.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: March 10, 2020
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, Nhung Tuyet Nguyen, David C. Onthank, Tarakeshwar Vishwanath Anklekar, Charles Chester Van Kirk
  • Lipid-encapsulated gas microsphere compositions and related methods
    Patent number: 10583207
    Abstract: The invention provides, inter alia, improved lipid formulations used to generate lipid-encapsulated gas microspheres, and methods of their use.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: March 10, 2020
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, David C. Onthank, Nhung Tuyet Nguyen
  • METHODS AND DEVICES FOR PREPARATION OF ULTRASOUND CONTRAST AGENTS
    Publication number: 20200000943
    Abstract: Provided herein are methods and devices for identifying and/or distinguishing UCA formulations and specifically activating such formulations to produce UCA suitable for in vivo use.
    Type: Application
    Filed: September 3, 2019
    Publication date: January 2, 2020
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Carol Walker, David C. Onthank, Joel Lazewatsky, Nhung Tuyet Nguyen
  • Compositions, methods, and systems for the synthesis and use of imaging agents
    Patent number: 10500293
    Abstract: The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: December 10, 2019
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Richard R. Cesati, Heike S. Radeke, Suresh K. Pandey, Ajay Purohit, Simon P. Robinson
  • METHODS FOR MAKING ULTRASOUND CONTRAST AGENTS
    Publication number: 20190255197
    Abstract: Provided herein are improved methods for preparing phospholipid formulations including phospholipid UCA formulations.
    Type: Application
    Filed: July 5, 2017
    Publication date: August 22, 2019
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, Nhung Tuyet Nguyen, David C. Onthank, Tarakeshwar Vishwanath Anklekar, Charles Chester Van Kirk
  • METHODS FOR MAKING ULTRASOUND CONTRAST AGENTS
    Publication number: 20190201559
    Abstract: Provided herein are improve methods for preparing phospholipid formulations including phospholipid UCA formulations.
    Type: Application
    Filed: January 31, 2019
    Publication date: July 4, 2019
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, Nhung Tuyet Nguyen, David C. Onthank, Tarakeshwar Vishwanath Anklekar, Charles Chester Van Kirk
  • METHODS FOR MAKING ULTRASOUND CONTRAST AGENTS
    Publication number: 20190142978
    Abstract: Provided herein are improved methods for preparing phospholipid formulations including phospholipid UCA formulations.
    Type: Application
    Filed: February 6, 2018
    Publication date: May 16, 2019
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, Nhung Tuyet Nguyen, David C. Onthank, Tarakeshwar Vishwanath Anklekar, Charles Chester Van Kirk
  • CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING
    Publication number: 20190127333
    Abstract: The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the patient using diagnostic imaging.
    Type: Application
    Filed: September 27, 2018
    Publication date: May 2, 2019
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: David S. Casebier, Simon P. Robinson, Ajay Purohit, Heike S. Radeke, Michael T. Azure, Douglas D. Dischino
  • Contrast agents for applications including perfusion imaging
    Patent number: 10245332
    Abstract: The present invention is directed, in part, to compounds and methods for imaging the central nervous system or cancer, comprising administering to a subject a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the subject using diagnostic imaging.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: April 2, 2019
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, David S. Casebier, Ming Yu, Mikhail Kagan, Joel Lazewatsky
  • Methods for making ultrasound contrast agents
    Patent number: 10220104
    Abstract: Provided herein are improved methods for preparing phospholipid formulations including phospholipid UCA formulations.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: March 5, 2019
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, Nhung Tuyet Nguyen, David C. Onthank, Tarakeshwar Vishwanath Anklekar, Charles Chester Van Kirk
  • LIGANDS FOR IMAGING CARDIAC INNERVATION
    Publication number: 20180339070
    Abstract: Novel compounds that find use as imaging agents within nuclear medicine applications (PET imaging) for imaging of cardiac innervation are disclosed. These PET based radiotracers may exhibit increased stability, decreased NE release (thereby reducing side effects), improved quantitative data, and/or high affinity for VMAT over prior radiotracers. Methods of using the compounds to image cardiac innervation are also provided. In some instances the compounds are developed by derivatizing certain compounds with 18F in a variety of positions: aryl, alkyl, a keto, benzylic, beta-alkylethers, gamma-propylalkylethers and beta-proplylalkylethers. Alternatively or additionally, a methyl group a is added to the amine, and/or the catechol functionality is either eliminated or masked as a way of making these compounds more stable.
    Type: Application
    Filed: May 22, 2018
    Publication date: November 29, 2018
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Ajay Purohit, Thomas D. Harris, Heike S. Radeke, Simon P. Robinson, Ming Yu, David S. Casebier, Michael T. Azure
  • COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS
    Publication number: 20180318456
    Abstract: The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.
    Type: Application
    Filed: January 31, 2018
    Publication date: November 8, 2018
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Richard R. Cesati, Heike S. Radeke, Suresh K. Pandey, Ajay Purohit, Simon P. Robinson
  • METHODS FOR MAKING ULTRASOUND CONTRAST AGENTS
    Publication number: 20180221516
    Abstract: Provided herein are improved methods for preparing phospholipid formulations including phospholipid UCA formulations.
    Type: Application
    Filed: March 29, 2018
    Publication date: August 9, 2018
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, Nhung Tuyet Nguyen, David C. Onthank, Tarakeshwar Vishwanath Anklekar, Charles Chester Van Kirk
  • Lipid-encapsulated gas microsphere compositions and related methods
    Patent number: 10022460
    Abstract: The invention provides, inter alia, improved lipid formulations used to generate lipid-encapsulated gas microspheres, and methods of their use.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: July 17, 2018
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, Robert W. Siegler, David C. Onthank, Nhung Tuyet Nguyen
  • Ligands for imaging cardiac innervation
    Patent number: 10010631
    Abstract: Novel compounds that find use as imaging agents within nuclear medicine applications (PET imaging) for imaging of cardiac innervation are disclosed. These PET based radiotracers may exhibit increased stability, decreased NE release (thereby reducing side effects), improved quantitative data, and/or high affinity for VMAT over prior radiotracers. Methods of using the compounds to image cardiac innervation are also provided. In some instances the compounds are developed by derivatizing certain compounds with 18F in a variety of positions: aryl, alkyl, a keto, benzylic, beta-alkylethers, gamma-propylalkylethers and beta-proplylalkylethers. Alternatively or additionally, a methyl group a is added to the amine, and/or the catechol functionality is either eliminated or masked as a way of making these compounds more stable.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: July 3, 2018
    Assignee: Lantheus Medical Imaging, Inc.
    Inventors: Ajay Purohit, Thomas D. Harris, Heike S. Radeke, Simon P. Robinson, Ming Yu, David S. Casebier, Michael T. Azure
  • CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING
    Publication number: 20180133347
    Abstract: The present invention is directed, in part, to compounds and methods for imaging the central nervous system or cancer, comprising administering to a subject a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the subject using diagnostic imaging.
    Type: Application
    Filed: May 12, 2016
    Publication date: May 17, 2018
    Applicant: Lantheus Medical Imaging, Inc.
    Inventors: Simon P. Robinson, David S. Casebier, Ming Yu, Mikhail Kagan, Joel Lazewatsky