Patents by Inventor Snezana Drmanac

Snezana Drmanac has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel human genes and gene expression products I
    Publication number: 20030065156
    Abstract: This invention relates to novel human polynucleotides and variants thereof, their encoded polypeptides and variants thereof, to genes corresponding to these polynucleotides and to proteins expressed by the genes. The invention also relates to diagnostic and therapeutic agents employing such novel human polymucleotides, their corresponding genes or gene products, e.g., these genes and proteins, including probes, antisense constructs, and antibodies.
    Type: Application
    Filed: February 15, 2002
    Publication date: April 3, 2003
    Inventors: Lewis T. Williams, Jaime Escobedo, Michael A. Innis, Pablo Dominguez Garcia, Julie Sudduth-Klinger, Christoph Reinhard, Klause Giese, Filippo Randazzo, Giulia C. Kennedy, David Pot, Atlaf Kassam, George Lamson, Radoje Drmanac, Radomir Crkvenjakov, Mark Dickson, Snezana Drmanac, Ivan Labat, Dena Leshkowitz, David Kita, Veronica Garcia, Lee William Jones, Birgit Stache-Crain
  • Diagnostic and therapeutic methods using molecules differentially expressed in cancer cells
    Publication number: 20020076735
    Abstract: The invention provides materials and methods for determining the metastatic potential of a cell and for identifying cancerous cells by determining the presence or absence of one or more expression products of at least one gene that is differentially expressed between normal cells, nonmetastatic cells, cells of low metastatic potential, and cells of high metastatic potential.
    Type: Application
    Filed: May 10, 2001
    Publication date: June 20, 2002
    Inventors: Lewis T. Williams, Jaime Escobedo, Michael A. Innis, Pablo Dominguez Garcia, Julie Sudduth-Klinger, Christoph Reinhard, Klaus Giese, Filippo Randazzo, Giulia C. Kennedy, David Pot, Altaf Kassam, George Lamson, Radoje Drmanac, Radomir Crkvenjakov, Mark Dickson, Snezana Drmanac, Ivan Labat, Dena Leshkowitz, David Kita, Veronica Garcia, Lee William Jones, Birgit Stache-Crain
  • Three dimensional arrays for detection or quantification of nucleic acid species
    Patent number: 6383742
    Abstract: The present invention provides a method for detecting a target nucleic acid species including the steps of providing an array of probes affixed to a substrate and a plurality of labeled probes wherein each labeled probe is selected to have a first nucleic acid sequence which is complementary to a first portion of a target nucleic acid and wherein the nucleic acid sequence of at least one probe affixed to the substrate is complementary to a second portion of the nucleic acid sequence of the target, the second portion being adjacent to the first portion; applying a target nucleic acid to the array under suitable conditions for hybridization of probe sequences to complementary sequences; introducing a labeled probe to the array; hybridizing a probe affixed to the substrate to the target nucleic acid; hybridizing the labeled probe to the target nucleic acid; affixing the labeled probe to an adjacently hybridized probe in the array; and detecting the labeled probe affixed to the probe in the array.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: May 7, 2002
    Inventors: Radoje T. Drmanac, Snezana Drmanac
  • Use of mismatch cleavage to detect complementary probes
    Publication number: 20020048760
    Abstract: The present invention provides methods and reagents useful for a wide range of nucleic acid sequence analyses, including sequencing by hybridization.
    Type: Application
    Filed: April 2, 2001
    Publication date: April 25, 2002
    Applicant: Hyseq, Inc.
    Inventors: Snezana Drmanac, Chongjun Xu, Xiao-Hong Qian
  • Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
    Patent number: 6297006
    Abstract: The present invention provides a method for detecting a target nucleic acid species including the steps of providing an array of probes affixed to a substrate and a plurality of labeled probes wherein each labeled probe is selected to have a first nucleic acid sequence which is complementary to a first portion of a target nucleic acid and wherein the nucleic acid sequence of at least one probe affixed to the substrate is complementary to a second portion of the nucleic acid sequence of the target, the second portion being adjacent to the first portion; applying a target nucleic acid to the array under suitable conditions for hybridization of probe sequences to complementary sequences; introducing a labeled probe to the array; hybridizing a probe affixed to the substrate to the target nucleic acid; hybridizing the labeled probe to the target nucleic acid; affixing the labeled probe to an adjacently hybridized probe in the array; and detecting the labeled probe affixed to the probe in the array.
    Type: Grant
    Filed: March 4, 1997
    Date of Patent: October 2, 2001
    Assignee: Hyseq, Inc.
    Inventors: Radoje T. Drmanac, Snezana Drmanac, Aaron Hou, Brian Hauser