Abstract: Provided are immunoglobulin-binding protein variants with increased alkali tolerance, and uses thereof, and more particularly to immunoglobulin-binding protein variants with increased alkali tolerance relative to the wild type due to mutations in amino acids at specific positions in the B3 domain of the immunoglobulin-binding proteins

Abstract: In an embodiment a cathode for an all-solid-state battery includes a composite material comprising a cathode active material and a coating layer completely covering a surface of the cathode active material, wherein the coating layer comprises a first solid electrolyte and a second solid electrolyte.

Abstract: The present application relates to a solid oral preparation and a preparation method therefor, the preparation comprising granules, which comprise: as an active ingredient, a carbamate compound of chemical formula 1, or a pharmaceutically acceptable salt, an isomer, solvate or a hydrate thereof; a diluent; and a binder.

Abstract: The present disclosure relates to antioxidant for a polymer electrolyte membrane fuel cell electrode catalyst, which includes cerium hydrogen phosphate (HCe2(PO4)3(H2O)) in the form of a nanofiber, and an electrode and a membrane-electrode assembly including the same. The electrode for a polymer electrolyte membrane fuel cell of the present disclosure, wherein the antioxidant is dispersed, can improve the mechanical strength of an electrode catalyst layer and can minimize deterioration of chemical durability even after long-term operation. And, a fuel cell including the same can exhibit high output performance and can operate stably even after long-term operation.

Abstract: An apparatus for obtaining a target signal spectrum includes: a spectrum measurer configured to measure a plurality of spectra from an object; and a processor configured to obtain a difference spectrum matrix by subtracting a reference spectrum from each of the plurality of spectra, and to obtain a spectrum of a target signal based on the obtained difference spectrum matrix.

Abstract: An optical multilayer structure including a hard coating layer, a low-reflective adhesion reinforcement layer, and a water repellent layer on a substrate layer. The optical multilayer structure includes a structure in which a hard coating layer, a low-reflective adhesion reinforcement layer including a siloxane-based compound, and a water repellent layer including an alkoxysilane-based compound containing a fluorine atom are laminated on a substrate layer, thereby having high wear resistance and water contact angle simultaneously.

Abstract: Disclosed are a lithium-ion supply electrode for real-time microscopic analysis and a method of manufacturing same. The lithium-ion supply electrode includes a solid electrolyte layer including a solid electrolyte, a lithium layer formed on the solid electrolyte layer and including lithium, and a protective layer formed on the lithium layer and including a metal. Therefore, lithium in the electrode does not undergo oxidation in a short time. Therefore, the lithium-ion supply electrode can be used for real-time analysis of structural changes and interfacial reactions of lithium secondary battery materials using a transmission electron microscope.

Abstract: The present technology provides triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The triazolone derivatives or their pharmaceutically acceptable salts exhibit selective inhibitory activity on VAP-1 and therefore can be usefully applied, e.g. for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).

Abstract: A display device comprising: a substrate; a plurality of display elements disposed on the substrate; and a diffraction pattern layer disposed on a path of light emitted from the plurality of display elements. The diffraction pattern layer comprises a plurality of diffraction patterns which is disposed with a predetermined pitch, and the plurality of diffraction patterns do not overlap the plurality of display elements; and when a width of a cross section of each of the plurality of diffraction patterns is defined as a length of each diffraction pattern, the predetermined pitch and the length of each diffraction pattern satisfy the following inequation: 0.4?d1/DP1<1, where DP1 denotes the predetermined pitch, and d1 denotes the length of each diffraction pattern.

Abstract: An air cleaning apparatus of a ventilation seat, may include a housing including a flow path configured to allow air to move therethrough; a photocatalyst located in the flow path of the housing and rotatably coupled to the housing to be rotatable with respect to the housing; and a UV LED fixed at the housing and configured to emit light of a light source toward the photocatalyst when power is supplied to the UV LED.

Abstract: The present invention relates to a 3-((8-((1H-pyrazol-4-yl)amino)imidazo[1,2-a]pyridin-3-yl)ethynyl)-N-phenylbenzamide derivative, a method for preparing the same, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating cancer. The derivative can significantly inhibit the proliferation of cancer cells by inhibiting kinases, particularly Bcr-Abl kinase or Bcr-Abl (T315I) kinase. Therefore, the derivative can be effectively used as a pharmaceutical composition for the prevention or treatment of cancer.

Abstract: The present disclosure relates to an organic electroluminescent device including a first electrode; a second electrode; and at least one light-emitting layer(s) positioned between the first electrode and the second electrode, and wherein the light-emitting layer includes a host comprising a compound represented by formula 1 and a compound represented by formula 2, and a dopant comprising a compound represented by formula 3, so that the present disclosure may provide an organic electroluminescent device having high efficiency and long lifespan property.

Abstract: A healthcare apparatus according to an embodiment includes: a plurality of light sources configured to emit light of different wavelengths onto an object; a light detector configured to measure an optical signal of each of the wavelengths by receiving light reflected or scattered from the object; and a processor configured to obtain a blood glucose level and a blood flow index by using the optical signal of each of the wavelengths, and to estimate at least one from among dietary information and dietary metabolism state information by monitoring a blood glucose level change and a blood flow index change after ingestion of a food.

Abstract: An apparatus for estimating body temperature of an object is provided. The apparatus for estimating body temperature includes: a sensor configured to obtain spectra through a plurality of light paths of an object; and a processor configured to obtain a temperature slope between temperatures corresponding to the plurality of light paths based on the spectra of the plurality of light paths and a reference spectrum measured at a reference temperature, and estimate the body temperature of the object based on the temperature slope.

Abstract: The present technology provides 3,3-difluoroallylamines or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. The 3,3-difluoroallylamines or their pharmaceutically acceptable salts exhibit potent inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).

Abstract: The present invention pertains to an anode-less lithium ion battery comprising a) a cathode comprising a cathode current collector and a cathode electro-active material on the cathode current collector; b) an anode current collector; c) a liquid electrolyte composition between the a) cathode and the b) anode current collector; and d) a separator, wherein the c) liquid electrolyte composition comprises i) at least 70% by volume (vol %) of a solvent mixture with respect to the total volume of the electrolyte composition, comprising at least one fluorinated ether compound and at least one non-fluorinated ether compound, and ii) at least one lithium salt.

Abstract: An outpatient prediction method includes obtaining, by an outpatient prediction apparatus, data on a target to be predicted, obtaining, by the outpatient prediction apparatus, past data including at least one of a number of outpatient clinic units in past, a number of outpatients in past, a number of blood-collecting patients in past, a number of computed tomography (CT)/magnetic resonance imaging (MRI) tests in past, a number of outpatients per outpatient clinic unit in past, a number of blood-collecting patients per outpatient number in past, and a number of CT/MRI tests per outpatient number in past, calculating, by the outpatient prediction apparatus, pattern data based on the past data, and predicting, by the outpatient prediction apparatus, at least one of a number of outpatients in future, a number of blood-collecting patients in future, and a number of CT/MRI tests in future based on the pattern data.

Abstract: One aspect according to the present disclosure relates to a novel nucleic acid ligand which is a new class of nucleic acid compound, the existence of which was considered impossible in the prior art. The novel nucleic acid ligand has specific binding affinity with respect to at least two different targets having three-dimensional structures, and the binding sites for the at least two targets are formed in or from a single nucleic acid ligand. The novel nucleic acid ligand according the present disclosure can simultaneously solve several problems of existing aptamers that the prior art could not solve. One aspect according to the present disclosure relates to a novel screening method for identifying the above-mentioned novel nucleic acid ligand. The novel screening method uses a step for sequentially contacting at least two different targets having three-dimensional structures to screen a novel nucleic acid ligand that was previously thought impossible.

Abstract: The present disclosure provides a substrate processing apparatus capable of stabilizing the particle level when re-supplying a chemical solution. The substrate processing apparatus includes a circulation line connected to a chemical supply unit to circulate a chemical solution, a filter installed in the circulation line to filter particles in the chemical solution, a supply line connected to a first node of the circulation line and configured to supply the chemical solution to the chamber, and a drain line connected, in the circulation line, to a second node located between the filter and the first node, and configured to drain the chemical solution, the apparatus being configured to operate, during a first duration, from when a pump of the chemical supply unit is restarted after the pump had stopped, to drain the chemical solution that passes through the filter.

Abstract: A display apparatus includes an oxide semiconductor pattern disposed on a device substrate and including a channel region disposed between a source region and a drain region, a gate electrode overlapping the channel region of the oxide semiconductor pattern and having a structure in which a first hydrogen barrier layer and a gate conductive layer are stacked, and a gate insulating film disposed between the oxide semiconductor pattern and the gate electrode to expose the source region and the drain region of the oxide semiconductor pattern. The gate electrode exposes a portion of the gate insulating film that is adjacent to the source region and a portion of the gate insulating film that is adjacent to the drain region.