Abstract: A highly glycosylated human blood-clotting factor VIII (FVIII) fusion protein, and a manufacturing method and application of same. The fusion protein comprises, from the N-terminus to the C-terminus, a human (FVIII), a flexible peptide connector, at least one rigid unit of a human chorionic gonadotropin ?-subunit carboxyl terminal peptide, and a half-life extending portion (preferentially selected from a human IgG Fc variant). The fusion protein has a similar level of biological activity as a recombinant (FVIII) and an extended in vivo half-life, thereby improving pharmacokinetics and drug efficacy.

Abstract: A highly glycosylated human blood-clotting factor VIII (FVIII) fusion protein, and a manufacturing method and application of same. The fusion protein comprises, from the N-terminus to the C-terminus, a human (FVIII), a flexible peptide connector, at least one rigid unit of a human chorionic gonadotropin ?-subunit carboxyl terminal peptide, and a half-life extending portion (preferentially selected from a human IgG Fc variant). The fusion protein has a similar level of biological activity as a recombinant (FVIII) and an extended in vivo half-life, thereby improving pharmacokinetics and drug efficacy.

Abstract: A method of Noisy Window and associated management messages to support set splitting if activating ONUs with uncalibrated transmitter, offering a power grant for unmodulated upstream transmission, measuring the average received optical power in all upstream wavelength channels and providing downstream indication of the upstream wavelength channel with abnormally high average received power.

Abstract: Provided are transmitting, receiving and communication systems of an optical network and a method for modulating a signal. The transmitting system includes: first Passive Optical Network (PON) equipment, configured to output a binary digital signal; and an M-order digital modulator, configured to modulate the binary digital signal into an M-order digital signal, and output the M-order digital signal, wherein each transmission symbol in the M-order digital signal carries information of N=log2M bits, where N is a natural number greater than 1 and M is a natural number. By the disclosure, the problems in the related art is solved, the bandwidths required by transmission are further reduced, and the actual cost of the optical transceiver modules is lowered.

Abstract: An optical-electrical receiving and transmitting method and apparatus, as well as an optical-electrical transceiving method and device and an optical-electrical transceiver are provided. The optical-electrical transceiving processing method may include: in a reception direction, a received optical signal is split into multipath optical signals, the multipath optical signals are processed into multipath parallel electrical signals, and the multipath parallel electrical signals are converted into a single-path serial electrical signal; in a transmission direction, a received single-path serial electrical signal, which is to be transmitted, is converted into multipath parallel electrical signals, then the multipath parallel electrical signals are processed into multipath optical signals, and finally the multipath optical signals are combined into a single beam of optical signals.

Abstract: An optical module and an optical device applicable to the optical module, wherein the optical module includes a laser emission unit, a laser reception unit, a video detector and an optical assembly, the optical assembly including: a band-pass device F1 with a small-angle incidence filter sheet, wherein among optical signals transmitted to F1 via a common port of F1, the optical signal in a first optical wavelength band is passed by the small-angle incidence filter sheet and output to the video detector via the passing port thereof; and the optical signals in other bands are reflected by the small-angle incidence filter sheet and output via the reflection port thereof; a filter sheet F2 configured to pass the optical signal emitted by the laser emission unit to the reflection port of F1 and to reflect the optical signal, received by the laser reception unit, output via the reflection port of F1.

Abstract: The embodiments of the present disclosure disclose a method for processing optical signals, an optical module, an Optical Line Terminal (OLT) optical signal processing method and an OLT. The optical module includes two photoelectric transmitter and receiver units and a Wavelength Division Multiplexing (WDM) unit. Each photoelectric transmitter and receiver unit is configured to generate a downstream optical signal with a corresponding rate and wavelength according to an electric signal, and then output the downstream optical signal to the WDM unit; and receive an upstream optical signal outputted by the WDM unit with a rate and wavelength corresponding to a burst mode, and convert the upstream optical signal into the electric signal.

Abstract: Disclosed is use of andrographolide derivative as shown by general formula 1 in manufacture of medicaments for anti-hepatitis C virus, and preventing and treating immunological liver damage caused by virus infection and different chemical liver damage.

Abstract: Disclosed are a method and device for transmitting optical signals. The method comprises: if there is Raman crosstalk between a first optical network system and a coexistence system, an upstream wavelength band of the first optical network system is set outside a range with an upstream wavelength band of the coexistence system being a center and with an impact intensity of the Raman crosstalk being a radius, and a downstream wavelength band of the first optical network system is set outside a range with the downstream wavelength band of the coexistence system being a center and with the impact intensity of the Raman crosstalk being a radius; and optical signals are transmitted by using the upstream wavelength band of the first optical network system and the downstream wavelength band of the first optical network system. The disclosure can avoid interference and improve signal quality.

Abstract: A method of Noisy Window and associated management messages to support set splitting if activating ONUs with uncalibrated transmitter, offering a power grant for unmodulated upstream transmission, measuring the average received optical power in all upstream wavelength channels and providing downstream indication of the upstream activation in the optical communication network wavelength channel with abnormally high average received power.

Abstract: An optical module and an optical device applicable to the optical module, wherein the optical module includes a laser emission unit, a laser reception unit, a video detector and an optical assembly, the optical assembly including: a band-pass device F1 with a small-angle incidence filter sheet, wherein among optical signals transmitted to F1 via a common port of F1, the optical signal in a first optical wavelength band is passed by the small-angle incidence filter sheet and output to the video detector via the passing port thereof; and the optical signals in other bands are reflected by the small-angle incidence filter sheet and output via the reflection port thereof; a filter sheet F2 configured to pass the optical signal emitted by the laser emission unit to the reflection port of F1 and to reflect the optical signal, received by the laser reception unit, output via the reflection port of F1.

Abstract: Provided are transmitting, receiving and communication systems of an optical network and a method for modulating a signal. The transmitting system includes: first Passive Optical Network (PON) equipment, configured to output a binary digital signal; and an M-order digital modulator, configured to modulate the binary digital signal into an M-order digital signal, and output the M-order digital signal, wherein each transmission symbol in the M-order digital signal carries information of N=log2M bits, where N is a natural number greater than 1 and M is a natural number. By the disclosure, the problems in the related art is solved, the bandwidths required by transmission are further reduced, and the actual cost of the optical transceiver modules is lowered.

Abstract: Disclosed is use of andrographolide derivative as shown by general formula 1 in manufacture of medicaments for anti-hepatitis C virus, and preventing and treating immunological liver damage caused by virus infection and different chemical liver damage.

Abstract: A method for amplifying and dynamically adjusting an optical signal is provided in the present invention, which includes: a first optical tap splitting out a small part of the optical signal, which is converted into an electric signal via a first optical detector and is then output to a high speed gain control circuit, in proportion from an uplink burst optical signal, and outputting a remainder of the optical signal to an optical amplifier; the high speed gain control circuit dynamically adjusting the control signal loaded on the optical amplifier according to the input electric signal which varies with uplink burst slots; and the optical amplifier dynamically adjusting a gain value according to the loaded control signal to make peak powers of the output uplink optical signals in different burst slots equal, thus achieving output power equalization.

Abstract: Disclosed are a method and device for transmitting optical signals. The method comprises: if there is Raman crosstalk between a first optical network system and a coexistence system, an upstream wavelength band of the first optical network system is set outside a range with an upstream wavelength band of the coexistence system being a center and with an impact intensity of the Raman crosstalk being a radius, and a downstream wavelength band of the first optical network system is set outside a range with the downstream wavelength band of the coexistence system being a center and with the impact intensity of the Raman crosstalk being a radius; and optical signals are transmitted by using the upstream wavelength band of the first optical network system and the downstream wavelength band of the first optical network system. The disclosure can avoid interference and improve signal quality.

Abstract: The disclosure provides an optical network system, an Optical Line Terminal (OLT), an Optical Network Unit (ONU) and an Optical Distribution Network (ODN) apparatus. The system includes: an OLT configured to modulate and encode at least one line of time-division-multiplexed downlink signals, synthesize the downlink signals encoded into one line and then output it, receive uplink signals, and decode the uplink signals received and then output them; an ODN configured to separate the downlink signals received into multiple lines and then output them, synthesize the uplink signals received into one line, and then output it to the OLT; and ONUs configured to receive the downlink signals output from the ODN, decode the downlink signals received and output them, encode one line of time-division-multiplexed uplink signals, and output the uplink signals encoded to the ODN. Decoding of the downlink signals and encoding of the uplink signals can further be implemented by the ODN.

Abstract: A wavelength division multiplexer is provided by the present invention, which implements the wavelength division multiplexing and de-multiplexing of the optical signals in the basic and upgrade bands by reasonably arranging the filters and selecting the spectral properties of the filters, so that the existing time division multiplexing passive optical network (TDM-PON) can transmit the next generation passive optical network (NG-PON) simultaneously and the existing TDM-PON can be smoothly upgraded to the NG-PON, meanwhile, it provides the deployed TDM-PON with the subsequent network compatibility. The wavelength division multiplexer provided in the present invention can meet the high isolation requirement of the optical signals in working band with low cost, and takes both the isolation requirement and the optical network insertion loss requirement into account, thus it has high reliability, is easy to use and for system upgrade.

Abstract: A wavelength division and time division hybrid multiplexing passive optical network system, terminals and a signal transmission method are disclosed in the present invention. The system comprises: a plurality of optical modules at the optical line terminal side connecting to an office all-optical wavelength conversion unit, the all-optical wavelength conversion unit connecting with a subscriber all-optical wavelength conversion unit via a fiber, and the subscriber all-optical wavelength conversion unit connecting with a plurality of optical couplers, and each optical couplers connecting with a plurality of optical network units respectively; the present invention facilitates full use of the existing source of access network and ensures a smooth transition from the time division multiplexing passive optical network to the optical access network of the next generation without changing the structure of the current time division passive optical network.

Abstract: The disclosure provides an optical network system, an Optical Line Terminal (OLT), an Optical Network Unit (ONU) and an Optical Distribution Network (ODN) apparatus. The system includes: an OLT configured to modulate and encode at least one line of time-division-multiplexed downlink signals, synthesize the downlink signals encoded into one line and then output it, receive uplink signals, and decode the uplink signals received and then output them; an ODN configured to separate the downlink signals received into multiple lines and then output them, synthesize the uplink signals received into one line, and then output it to the OLT; and ONUs configured to receive the downlink signals output from the ODN, decode the downlink signals received and output them, encode one line of time-division-multiplexed uplink signals, and output the uplink signals encoded to the ODN. Decoding of the downlink signals and encoding of the uplink signals can further be implemented by the ODN.

Abstract: A method for amplifying and dynamically adjusting an optical signal is provided in the present invention, which includes: a first optical tap splitting out a small part of the optical signal, which is converted into an electric signal via a first optical detector and is then output to a high speed gain control circuit, in proportion from an uplink burst optical signal, and outputting a remainder of the optical signal to an optical amplifier; the high speed gain control circuit dynamically adjusting the control signal loaded on the optical amplifier according to the input electric signal which varies with uplink burst slots; and the optical amplifier dynamically adjusting a gain value according to the loaded control signal to make peak powers of the output uplink optical signals in different burst slots equal, thus achieving output power equalization.