Patents by Inventor Sophie Carayon

Sophie Carayon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10005835
    Abstract: The present invention provides stable pharmaceutical antibody formulations, including lyophilized formulations, comprising an anti-IL-4/anti-IL-13 bispecific antibody and a buffering system, wherein the pH of the formulation is about pH 7, and wherein the formulation has a low salt concentration in order to reduce the ionic strength of the formulation. The formulations may, optionally, further comprise a non-ionic surfactant, a sugar, and/or a non-ionic stabilizing agent. The formulations can be used in the treatment of various diseases.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: June 26, 2018
    Assignee: SANOFI
    Inventors: Sophie Carayon, Otmane Boussif
  • Publication number: 20160075777
    Abstract: The present invention provides stable pharmaceutical antibody formulations, including lyophilized formulations, comprising an anti-IL-4/anti-IL-13 bispecific antibody and a buffering system, wherein the pH of the formulation is about pH 7, and wherein the formulation has a low salt concentration in order to reduce the ionic strength of the formulation. The formulations may, optionally, further comprise a non-ionic surfactant, a sugar, and/or a non-ionic stabilizing agent. The formulations can be used in the treatment of various diseases.
    Type: Application
    Filed: April 29, 2014
    Publication date: March 17, 2016
    Inventors: Sophie Carayon, Otmane Boussif
  • Publication number: 20150225479
    Abstract: The present invention provides stable pharmaceutical antibody formulations, including liquid formulations and lyophilized formulations, comprising an anti-IL-4/anti-IL-13 bispecific antibody, a polyaminoacid consisting of glutamic acid or aspartic acid or both randomly grafted with Vitamin E, and a cryoprotectant, wherein the formulation has a salt concentration of 50 mM or less. The present invention also provides stable pharmaceutical antibody formulations, including liquid formulations and lyophilized formulations, comprising an anti-IL-4/anti-IL-13 bispecific antibody, a polyaminoacid consisting of glutamic acid or aspartic acid or both randomly grafted with Vitamin E, a cryoprotectant, and a buffering system, wherein the pH of the formulation is about pH 7, and wherein the formulation has a salt concentration of 50 mM or less. The formulations may, optionally, further comprise a surfactant, or a stabilizing agent, or both. The present invention includes methods for making such formulations.
    Type: Application
    Filed: February 11, 2015
    Publication date: August 13, 2015
    Inventors: Sylvain Huille, Sophie Carayon, Corine Vialas, C├ęcile Bonnet-Gonnet, You-Ping Chan
  • Publication number: 20090127450
    Abstract: A method for measurement of relative fluorescence quantum efficiency of a dye, including: a) for at least two different concentrations of the dye in solution in a solvent, exciting the dye with electromagnetic radiation and measuring the photoluminescence of the dye that has been excited by the radiation and of the signal transmitted through the cell containing the dye; b) comparing the data measured with the photoluminescence and transmission data of a reference dye; and c) calculating the relative fluorescence quantum efficiency of the dye.
    Type: Application
    Filed: October 25, 2005
    Publication date: May 21, 2009
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Joel Bleuse, Sophie Carayon, Eric Delamadeleine