Abstract: The present invention relates to an improved process for preparation of Ozanimod (I) or pharmaceutically acceptable salts thereof. The present invention also relates to an improved process for preparation of (S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile (II) or its optically active acid salts.

Abstract: The invention relates to a process for producing a fraction enriched upto 100% of 3-O-acetyl-11-keto-?-boswellic acid. An organic solvent extract of gum resin from Boswellia species is first subjected to oxidation and then acetylation or vice versa. This converts the less potent boswellic acids present in the fraction to AKBA. This treated fraction is subjected to further purification and separation by chromatographic separation techniques to enhance its purity and to remove contaminants therefrom. This process provide an access to a fraction enriched in 10-100% AKBA for therapeutic applications.

Abstract: This invention relates to novel double salt of (?)-hydroxycitric acid with an amine and zinc or a group II A metal. These compounds are stable and water soluble and are used as nutraceuticals, weight reducing agents and in beverages. The double salts have the following general formula (I) Wherein X is zinc or a metal belonging to group II A of the Periodic Table and Y is glucosamine, caffeine or a known anorexic amine residue.

Abstract: The invention relates to extraction concentration and separation of fractions containing Bacosides A and B from plant materials of Bacopa species. The dried plant materials are subjected to alcoholic or hydroalcoholic or water extraction and concentration of the extract. This solid mass is washed with a nonpolar organic solvent to remove fatty materials therefrom. The solid obtained thereafter is extracted with an organic polar solvent, the solvent extract is washed with water to remove water soluble contaminants therefrom and then dried in vacuum. This factor which is enriched with Bacosides A and B is subjected repeated chromatographic separation and purification to obtain Bacoside A and Bacoside B therefrom.

Abstract: This invention relates to a novel process for preparing highly water soluble alkaline earth metal and alkali metal double salts of hydroxycitric acid. These salts are practically odourless and has negligible taste and are therefor useful as nutraceuticals. Aqueous extract of the fruits belonging to Garcinia species are treated to precipitate its alkaline earth metal salts such as the calcium salt. This sparingly soluble product is dissolved in alkali hydroxide and the pH of the solution is adjusted by adding purified extract of the fruit rind. Ca/Na or Ca/K double salts are particularly useful.

Abstract: This invention relates to a novel process for preparing highly water soluble alkaline earth metal and alkali metal double salts of hydroxycitric acid. These salts are practically odourless and has negligible taste and are therefor useful as nutraceuticals. Aqueous extract of the fruits belonging to Garcinia species are treated to precipitate its alkaline earth metal salts such as the calcium salt. This sparingly soluble product is dissolved in alkali hydroxide and the pH of the solution is adjusted by adding purified extract of the fruit rind. Ca/Na or Ca/K double salts are particularly useful.

Abstract: The invention relates to a process for producing a fraction enriched upto 100% of 3-O-acetyl-11-keto-&bgr;-boswellic acid. An organic solvent extract of gum resin from Boswellia species is first subjected to oxidation and then acetylation or vice versa. This converts the less potent boswellic acids present in the fraction to AKBA. This treated fraction is subjected to further purification and separation by chromatographic separation techniques to enhance its purity and to remove contaminants therefrom. This process provide an access to a fraction enriched in 10-100% AKBA for therapeutic applications.