Patents by Inventor Sriram Padmanabhan

Sriram Padmanabhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030152589
    Abstract: The invention features incapacitated whole cell bacterial immunogenic compositions produced by infecting a bacterium with Lys minus bacteriophage, which are deficient in the lysin protein. Lys minus bacteriophage retain activity in infection of its appropriate bacterial host, destruction of the bacterial genome, and replication, which are sufficient to inhibit bacterial growth and replication. The resulting, Lys minus-infected bacterium is provided in a state of bacteriostasis, and is not capable of replicating further (e.g., is “incapacitated”). The incapacitated bacterium can then be used as to elicit an immune response for prophylactic and/or therapeutic purposes. The invention thus also features incapacitated bacteria formulated appropriately for use in immunogenic compositions for eliciting an immune response, e.g., for production of antibodies in a non-human host or in a whole cell bacterial vaccine.
    Type: Application
    Filed: September 27, 2002
    Publication date: August 14, 2003
    Inventors: Janakiraman Ramachandran, Sriram Padmanabhan, Bharathi Sriram
  • Publication number: 20030123671
    Abstract: Disclosed is a method of internally encrypting data in a relational database, comprising the steps of providing a security dictionary comprising one or more security catalogs, receiving data from a user associating said data with a database column and at least one authorized user, generating a working encryption key, internally encrypting said working encryption key using a public key from an authorized user, storing said encrypted working key in a security catalog, and using said working key to internally encrypt said data.
    Type: Application
    Filed: December 28, 2001
    Publication date: July 3, 2003
    Applicant: International Business Machines Corporation
    Inventors: Jingmin He, Sriram Padmanabhan, MIn Wang
  • Publication number: 20030118558
    Abstract: The present invention features therapeutic bacteriophage deficient in the lysin protein (“Lys minus” phage). Lys minus bacteriophage are incapable of facilitating efficient lysis of the bacterial host since the enzymatic activity of the lysin of the phage is needed for breaking down the peptidoglycan layer of the bacterial cell wall. Lys minus bacteriophage retain activity in invasion of its appropriate bacterial host, destruction of the bacterial genome, and replication, which are sufficient to inhibit bacterial growth and replication. Therefore, the therapeutic Lys minus phage stops the spread of infection by the bacterial pathogen without lysis of the bacterium. This approach is attractive as it also prevents the release of the phage progeny, thus reducing or eliminating the potential for generation of immune responses against the phage. The incapacitated bacterial pathogen is then removed by the normal defense systems such as phagocytes and macrophages.
    Type: Application
    Filed: September 27, 2002
    Publication date: June 26, 2003
    Inventors: Janakiraman Ramachandran, Sriram Padmanabhan, Bharathi Sriram
  • Patent number: 6046377
    Abstract: Disclosed is an absorbent structure containing superabsorbent material, wettable staple fiber, and wettable binder fiber. The absorbent structure exhibits a liquid uptake rate greater than the liquid uptake rate exhibited by an otherwise identical absorbent structure without any wettable staple fiber. Also disclosed is an absorbent garment containing such an absorbent structure.
    Type: Grant
    Filed: August 22, 1994
    Date of Patent: April 4, 2000
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Andrew Edsel Huntoon, Randy Emil Meirowitz, Sriram Padmanabhan Anjur, Robert John Phelan, Kim Te Tang, Anthony John Wisneski
  • Patent number: 5849000
    Abstract: Disclosed is an absorbent structure containing hydrogel-forming polymeric material, wettable staple fiber, and wettable binder fiber. The absorbent structure exhibits improved z-direction permeability of a liquid as compared to an otherwise essentially identical absorbent structure which does not comprise a wettable binder fiber. Also disclosed is an disposable absorbent product containing such an absorbent structure.
    Type: Grant
    Filed: December 29, 1994
    Date of Patent: December 15, 1998
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Sriram Padmanabhan Anjur, Michael Franklin Kalmon, Anthony John Wisneski
  • Patent number: 5645542
    Abstract: Disclosed is an elastomeric absorbent structure containing wettable staple fiber and thermoplastic elastomeric fiber. The elastomeric absorbent structure exhibits improved elastic properties as compared to an otherwise essentially identical absorbent structure without any thermoplastic elastomeric fiber. Also disclosed is a disposable absorbent product containing such an elastomeric absorbent structure.
    Type: Grant
    Filed: December 29, 1994
    Date of Patent: July 8, 1997
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Sriram Padmanabhan Anjur, Ketan Narendra Shah, Anthony John Wisneski