Patents by Inventor Stefan Gabriel

Stefan Gabriel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7144703
    Abstract: Novel vaccine compositions are provided comprising a hepatitis B antigen formulated with aluminium phosphate. The vaccine compositions may additionally contain an inactivated hepatitis A virus, aluminium hydroxide and formol. The combined hepatitis A and B vaccine formulations can, if desired, be administered to human subjects in a 2 dose regimen. Suitable formulations are illustrated.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: December 5, 2006
    Assignee: SmithKline Beecham Biologicals, s.a.
    Inventors: Claude Artois, Michael J Clark, Stefan Gabriel Jozef Thoelen, Clothilde Thiriart
  • Patent number: 6955678
    Abstract: A surgical tool includes a member, a guide wire received within the member by a friction fit, and a guide wire pusher for application of a force to the guide wire to overcome the friction fit and advance the guide wire relative to the member. The member includes a guide wire retainer that provides the friction fit and allows the guide wire to be held in such a way that it is pre-assembled and secure while the tool is being introduced to a surgical site. At the same time, once a hole is drilled into bone, the guide wire retainer allows the remainder of the tool to be removed leaving the guide wire in place at the site. The guide wire pusher allows the guide wire to be impacted into the bone before drilling and limits any possibility of drilling past the end of the guide wire.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: October 18, 2005
    Assignee: Smith & Nephew, Inc.
    Inventors: Stefan Gabriel, Justin Dye
  • Publication number: 20040241193
    Abstract: Novel vaccine compositions are provided comprising a hepatitis B antigen formulated with aluminium phosphate. The vaccine compositions may additionally contain an inactivated hepatitis A virus, aluminium hydroxide and formol. The combined hepatitis A and B vaccine formulations can, if desired, be administered to human subjects in a 2 dose regimen. Suitable formulations are illustrated.
    Type: Application
    Filed: July 1, 2004
    Publication date: December 2, 2004
    Applicant: SmithKline Beecham Biologicals, s.a.
    Inventors: Claude Artois, Michael J. Clark, Stefan Gabriel Jozef Thoelen, Clothilde Thiriart
  • Publication number: 20040111117
    Abstract: A bone anchor includes an anchor body configured to be retained within bone. The anchor body includes a restrictor defining an opening having a first portion for permitting passage of a member therethrough, and a second portion restricting passage of the member therethrough. The member is movable between the first and second portions in a direction non-parallel to a direction of passage of the member through the opening. The restrictor includes an edge lining the opening oriented obliquely to a direction of passage of the member through the opening. The anchor body includes one or more resilient members with sharp, proximal edges for penetrating bone tissue.
    Type: Application
    Filed: December 1, 2003
    Publication date: June 10, 2004
    Applicant: Smith & Nephew, Inc., a Delaware corporation
    Inventors: Dennis Colleran, Stefan Gabriel
  • Publication number: 20040073219
    Abstract: A method of deploying a fixation mechanism includes providing an insertion instrument and a fixation mechanism, creating an insertion tunnel within tissue of a patient, and positioning the insertion instrument with the fixation mechanism in the insertion tunnel. The insertion instrument includes a main member connected to an instrument handle and a secondary member connected to a pushing handle and positioned within the main member. The main member and the secondary member extend along a longitudinal axis. The fixation mechanism includes a first portion coupled to the main member and a second portion coupled to the secondary member. The method includes translating the pushing handle along the longitudinal axis relative to the instrument handle such that translating causes the secondary member to move the second portion relative to the first portion.
    Type: Application
    Filed: November 25, 2002
    Publication date: April 15, 2004
    Inventors: Jeffry B. Skiba, Jeffrey P. Baldwin, Dennis Colleran, Stefan Gabriel, Justin Dye
  • Publication number: 20040002709
    Abstract: A surgical tool includes a member, a guide wire received within the member by a friction fit, and a guide wire pusher for application of a force to the guide wire to overcome the friction fit and advance the guide wire relative to the member. The member includes a guide wire retainer that provides the friction fit and allows the guide wire to be held in such a way that it is pre-assembled and secure while the tool is being introduced to a surgical site. At the same time, once a hole is drilled into bone, the guide wire retainer allows the remainder of the tool to be removed leaving the guide wire in place at the site. The guide wire pusher allows the guide wire to be impacted into the bone before drilling and limits any possibility of drilling past the end of the guide wire.
    Type: Application
    Filed: June 28, 2002
    Publication date: January 1, 2004
    Inventors: Stefan Gabriel, Justin Dye
  • Patent number: 6656183
    Abstract: A bone anchor includes an anchor body configured to be retained within bone. The anchor body includes a restrictor defining an opening having a first portion for permitting passage of a member therethrough, and a second portion restricting passage of the member therethrough. The member is movable between the first and second portions in a direction non-parallel to a direction of passage of the member through the opening. The restrictor includes an edge lining the opening oriented obliquely to a direction of passage of the member through the opening. The anchor body includes one or more resilient members with sharp, proximal edges for penetrating bone tissue.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: December 2, 2003
    Assignee: Smith & Nephew, Inc.
    Inventors: Dennis Colleran, Stefan Gabriel
  • Publication number: 20030204193
    Abstract: A tool includes a housing adapted to receive an anchor with attached suture, and a suture retainer adapted to receive the attached suture. The suture retainer is configured to regulate deployment of the suture from the retainer such that deployment of the suture from the housing does not occur until a load applied to the suture corresponds to at least a selected minimum fixation strength of the anchor in bone. A method includes inserting a suture anchor at an attachment site, the suture anchor having an attached suture, and deploying the attached suture from a suture retainer when a load applied to the suture corresponds to at least a selected minimum fixation strength of the anchor in bone.
    Type: Application
    Filed: April 25, 2002
    Publication date: October 30, 2003
    Inventors: Stefan Gabriel, Dennis Colleran, Paul Vincuilla, Paul Salvas, Laird L. Hatch, Paul O'Connor
  • Publication number: 20030135239
    Abstract: A tissue anchor insertion tool includes a first member defining a region configured to receive a tissue anchor, and a second member positioned to substantially cover the tissue anchor during introduction to a surgical site. The second member is coupled to the first member such that relative motion between the members deploys the tissue anchor from the region. The first member includes an applicator configured to move laterally to deploy the anchor from the region. A method includes providing first and second members coupled for relative motion, inserting a tissue anchor into tissue using the first and second members, and relatively moving the first and second members to deploy the tissue anchor from the first member. The tissue anchor is mounted to the first member. The second member substantially covers the tissue anchor during the insertion into tissue.
    Type: Application
    Filed: January 16, 2002
    Publication date: July 17, 2003
    Inventors: Stefan Gabriel, Justin Dye
  • Publication number: 20030120309
    Abstract: An anchor includes an anchor body configured to be retained within base tissue. The anchor body includes a unidirectional mechanism to selectively restrict passage of a flexible member through the anchor. The flexible member includes a loop to enable attachment of candidate tissue to base tissue without the use of knots.
    Type: Application
    Filed: November 27, 2002
    Publication date: June 26, 2003
    Inventors: Dennis Colleran, Ian Trail, Stefan Gabriel, Justin Dye, George Sikora
  • Publication number: 20030088250
    Abstract: A bone anchor includes an anchor body configured to be retained within bone. The anchor body includes a restrictor defining an opening having a first portion for permitting passage of a member therethrough, and a second portion restricting passage of the member therethrough. The member is movable between the first and second portions in a direction non-parallel to a direction of passage of the member through the opening. The restrictor includes an edge lining the opening oriented obliquely to a direction of passage of the member through the opening. The anchor body includes one or more resilient members with sharp, proximal edges for penetrating bone tissue.
    Type: Application
    Filed: November 8, 2001
    Publication date: May 8, 2003
    Inventors: Dennis Colleran, Stefan Gabriel
  • Publication number: 20030049268
    Abstract: Novel vaccine compositions are provided comprising a hepatitis B antigen formulated with aluminium phosphate. The vaccine compositions may additionally contain an inactivated hepatitis A virus, aluminium hydroxide and formol. The combined hepatitis A and B vaccine formulations can, if desired, be administered to human subjects in a 2 dose regimen. Suitable formulations are illustrated.
    Type: Application
    Filed: August 20, 2002
    Publication date: March 13, 2003
    Applicant: SmithKline Beecham Biologicals s.a.
    Inventors: Claude Artois, Michael J. Clark, Stefan Gabriel Jozef Thoelen, Clothilde Thiriart
  • Patent number: 5732678
    Abstract: A spool valve (22) controls a hydraulic drive, such as a drive for a fuel pump (18) in an internal combustion engine, in which the hydraulic drive comprises a driving piston (34) journalled in a hydraulic cylinder (33) which through a flow passage (31) is in communication with the spool valve. The spool (38) may occupy a position in which the flow passage is connected with a high-pressure source (29) and another position in which the flow passage is connected with a low-pressure port (30). The spool is settable by means of a positioning means (23) electrically activated by a control unit (16) which determines intended positions of the spool and for a movable part (56) in the positioning member. The movable part has windings (51) positioned in a magnetic field in a slit (60) which is oblong in the longitudinal direction of the spool. A sensor (66) signalizes the actual position of the movable part to the control unit (16).
    Type: Grant
    Filed: December 4, 1995
    Date of Patent: March 31, 1998
    Assignee: Man B&W Diesel A/S
    Inventors: Henning Lindquist, Erik Rosenlund Hansen, Karel Hampejs, Stefan Gabriel
  • Patent number: 4790234
    Abstract: A fluidic power-assisted setting device has a setting motor having an output torque; a threaded spindle supported for rotation; a spindle nut threadedly mounted on the spindle for linear displacement; a setting member attached to the spindle nut for linear travel therewith; a gearing for transmitting the output torque of the setting motor to the spindle; a signalling device coupled to the gearing for generating an output signal when the linear force derived from the output torque of the setting motor is insufficient to overcome an external force opposing linear displacement of the setting member; and a fluidic power device including a hydraulic motor connected to the setting member for applying thereto a linear force to overcome the external force; and a hydraulic control valve hydraulically connecting the hydraulic motor with pressurized hydraulic fluid as a function of the output signal of the signalling device for causing the hydraulic motor to generate a force applied to the setting member for overcoming
    Type: Grant
    Filed: November 17, 1986
    Date of Patent: December 13, 1988
    Assignee: Sig Schweizerische Industrie-Gesellschaft
    Inventors: Karel Hampejs, Stefan Gabriel