Patents by Inventor Stephanie A. Sweetana

Stephanie A. Sweetana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Echinocandin pharmaceutical formulations containing micelle-forming surfactants
    Publication number: 20050192213
    Abstract: Pharmaceutical formulations are described comprising an echinocandin compound or echinocandin/carbohydrate complex and a pharmaceutically acceptable micelle-forming surfactant in a non-toxic aqueous solvent such that the solubilization of the echinocandin compound is optimized and the ability to freeze-dry the solution is maintained. Both the solution and freeze-dried formulations have increased stability. A bulking agent, tonicity agent buffer and/or a stabilizing agent may optionally be added to the formulations to further enhance the stability of the formulation.
    Type: Application
    Filed: April 11, 2005
    Publication date: September 1, 2005
    Inventors: Nathaniel Milton, Kenneth Moder, James Sabatowski, Stephanie Sweetana
  • Polypeptide composition for oral administration
    Patent number: 6156731
    Abstract: There is disclosed a composition containing a biologically active polypeptide selected from LHRH, an LHRH analog, somatostatin and a somatostatin analog, in a therapeutically effective amount, a membrane permeability enhancing agent, and a protease enzyme inhibitor enveloped within an enteric coating. The composition possesses enhanced bioavailability upon oral administration.
    Type: Grant
    Filed: December 5, 1995
    Date of Patent: December 5, 2000
    Assignee: G. D. Searle & Co.
    Inventors: George M. Grass, Stephanie A. Sweetana
  • Solid orally administerable raloxifene hydrochloride pharmaceutical formulation
    Patent number: 5972383
    Abstract: This invention provides orally administerable pharmaceutical formulations comprising raloxifene, its ethers or esters, or a pharmaceutically-acceptable salt thereof, in combination with a hydrophilic carrier composition.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: October 26, 1999
    Assignee: Eli Lilly and Company
    Inventors: Lowell L. Gibson, Kerry J. Hartauer, Julian L. Stowers, Stephanie A. Sweetana, Arvind L. Thakkar
  • Solid orally administerable raloxifene hydrochloride pharmaceutical formulation
    Patent number: 5811120
    Abstract: This invention provides solid orally administerable pharmaceutical formulations comprising raloxifene hydrochloride, a surfactant being sorbitan fatty acid ester or a polyoxyethylene sorbitan fatty acid ester, polyvinylpyrrolidone, and a water soluble diluent which is polyol or sugar.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: September 22, 1998
    Assignee: Eli Lilly and Company
    Inventors: Lowell L. Gibson, Kerry J. Hartauer, Julian L. Stowers, Stephanie A. Sweetana, Arvind L. Thakkar
  • Aqueous solution inclusion complexes of benzothiophene compounds with water soluble cyclodextrins, and pharmaceutical formulations and methods thereof
    Patent number: 5624940
    Abstract: The present invention provides aqueous inclusion complexes of certain known benzothiophene compounds, particularly Raloxifene, and water soluble cyclodextrins. Also provided are pharmaceutical compositions of such inclusion complexes, and methods of using these complexes for inhibiting bone loss and reducing serum cholesterol in mammals.
    Type: Grant
    Filed: June 30, 1995
    Date of Patent: April 29, 1997
    Assignee: Eli Lilly and Company
    Inventors: Henry U. Bryant, George J. Cullinan, Paul C. Francis, David E. Magee, Stephanie A. Sweetana, Arvind L. Thakkar
  • Apparatus for in vitro determination of substances across membranes, biological tissues, or cell cultures
    Patent number: 5183760
    Abstract: An apparatus for determining transport characteristics across membranes and tissue sections comprises a plurality of cell blocks, where each cell block includes a pair of half-cells which hold the membrane or tissure section therebetween. A circulation path is provided in each half-cell block for exposing a fluid to one side of the membrane or tissue section. The cell blocks are maintained linearly within a base unit including a front plate and a back plate. The front and back plates are heated to maintain the cell blocks at a desired temperature.
    Type: Grant
    Filed: April 12, 1991
    Date of Patent: February 2, 1993
    Inventors: Stephanie A. Sweetana, George M. Grass