Patents by Inventor Stephanos Ioannidis

Stephanos Ioannidis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLIC JAK KINASE INHIBITORS
    Publication number: 20110201628
    Abstract: The present invention relates to compounds of Formula (I) and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds provide a treatment for myeloproliferative disorders and cancer.
    Type: Application
    Filed: September 29, 2009
    Publication date: August 18, 2011
    Inventors: Claudio Edmundo Chuaqui, Shan Huang, Stephanos Ioannidis, Jie Shi, Mei Su, Qibin Su
  • 9-(PYRAZOL-3-YL)-9H-PURINE-2-AMINE AND 3-(PYRAZOL-3-YL) -3H-IMIDAZO[4,5-B] PYRIDIN-5- AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER
    Publication number: 20100324040
    Abstract: The present invention relates to compounds of Formula (I): and to their pharmaceutical compositions, and to their methods of use. These compounds provide a treatment for myeloproliferative disorders and cancer.
    Type: Application
    Filed: May 2, 2008
    Publication date: December 23, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Audrey Davies, Stephanos Ioannidis, Michelle Lamb, Mei Su, Tao Wang, Hai-Jun Zhang
  • 5-AMINOPYRAZOL-3-YL-3H-IMIDAZO (4,5-B) PYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER
    Publication number: 20100204246
    Abstract: The present invention relates to compounds of Formula (I) and to their pharmaceutical compositions, and to their methods of use. These novel compounds provide a treatment for myeloproliferative disorders and cancer.
    Type: Application
    Filed: April 17, 2008
    Publication date: August 12, 2010
    Applicant: AstraZeneca AB
    Inventors: Audrey Davies, Stephanos Ioannidis, Michelle Lamb, Tao Wang, Hai-Jun Zhang
  • AMINO-THIAZOLYL-PYRIMIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF CANCER
    Publication number: 20100204231
    Abstract: The present invention relates to compounds of Formula (I): and to their pharmaceutical compositions, and to their methods of use. These compounds provide a treatment for myeloproliferative disorders and cancer.
    Type: Application
    Filed: May 2, 2008
    Publication date: August 12, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Lynsie Almeida, Huiping Guan, Stephanos Ioannidis, Michelle Lamb, Go Peng
  • 4-(3-AMINOPYRAZOLE) PYRIMIDINE DERIVATIVES FOR USE AS TYROSINE KINASE INHIBITORS IN THE TREATMENT OF CANCER
    Publication number: 20100160325
    Abstract: This invention relates to novel compounds having the formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
    Type: Application
    Filed: February 26, 2010
    Publication date: June 24, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Xiaomei Feng, Huiping Guan, Stephanos Ioannidis, Bo Peng, Mei Su, Tao Wang, Hai-Jun Zhang, Ying Kan, Bin Wang
  • SUBSTITUTED HETEROCYCLES AND THEIR USE AS CHK1, PDK1 AND PAK INHIBITORS
    Publication number: 20090275570
    Abstract: The invention relates to novel compounds of Formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds possess CHK1 kinase inhibitory activity, PDK1 inhibitory activity and Pak kinase inhibitory activity and are accordingly useful in the treatment and/or prophylaxis of cancer.
    Type: Application
    Filed: April 5, 2006
    Publication date: November 5, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Kevin Daly, Nicola Heron, Alexander Hird, Stephanos Ioannidis, James Janetka, Paul Lyne, Jaime Scott, Dorin Toader, Melissa Vasbinder, Dingwei Yu, Yan Yu
  • SUBSTITUTED THIOPHENES AND USES THEREOF
    Publication number: 20090054396
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: September 8, 2008
    Publication date: February 26, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Susan Ashwell, Thomas Gero, Stephanos Ioannidis, James Janetka, Paul Lyne, Vibha Oza, Mei Su, Dingwei Yu, Stephanie Springer
  • Chemical Compounds-149
    Publication number: 20080312206
    Abstract: The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
    Type: Application
    Filed: December 19, 2006
    Publication date: December 18, 2008
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Donald Cook, Leslie Dakin, Stephanos Ioannidis, Paul Lyne, David Scott, Xiaolan Zheng
  • 4-(3-Aminopyrazole) Pyrimidine Derivatives for Use as Tyrosine Kinase Inhibitors in the Treatment of Cancer
    Publication number: 20080287475
    Abstract: This invention relates to novel compounds having the formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
    Type: Application
    Filed: October 26, 2006
    Publication date: November 20, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Xiaomei Feng, Huiping Guan, Ying Kan, Stephanos Ioannidis, Bo Peng, Mei Su, Bin Wang, Tao Wang, Hai-Jun Zhang
  • Substitute thiophenes and uses thereof
    Patent number: 7423061
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: September 9, 2008
    Assignee: AstraZeneca AB
    Inventors: Susan Ashwell, Thomas Gero, Stephanos Ioannidis, James Janetka, Paul Lyne, Vibha Oza, Stephanie Springer, Mei Su, Dingwei Yu
  • Quinoxalines as B Baf Inhhibitors
    Publication number: 20080207616
    Abstract: The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
    Type: Application
    Filed: October 13, 2005
    Publication date: August 28, 2008
    Applicant: AstraZeneca AB
    Inventors: Brian Aquila, Les Dakin, Tracy Deegan, Stephanos Ioannidis, Stephen Lee, Paul Lyne, Timothy Pontz, Mei Su
  • Azine-Carboxamides as Anti-Cancer Agents
    Publication number: 20070259849
    Abstract: The invention relates to chemical compounds, of the formula (I): or pharmaceutically acceptable salts thereof, which possess B-Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.
    Type: Application
    Filed: June 29, 2005
    Publication date: November 8, 2007
    Applicant: ASTRAZENECA AB
    Inventors: Brian Aquila, Stephanos Ioannidis, Paul Lyne, Timothy Pontz
  • Thiophene derivatives as chk 1 inhibitors
    Publication number: 20070010556
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: December 24, 2004
    Publication date: January 11, 2007
    Applicant: ASTRAZENECA AB
    Inventors: Susan Ashwell, Thomas Gero, Stephanos Ioannidis, James Janetka, Paul Lyne, Su Mei, Doria Toader, Dingwei Yu, Yan Yu
  • Substitute thiophenes and uses therof
    Publication number: 20060281666
    Abstract: This invention relates to novel compounds having the structural formula (I) and to their pharmaceutical salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cancer.
    Type: Application
    Filed: August 12, 2004
    Publication date: December 14, 2006
    Inventors: Susan Ashwell, Thomas Gero, Stephanos Ioannidis, James Janetka, Paul Lyne, Vibha Oza, Stephanie Springer, Mei Su, Dingwei Yu