Patents by Inventor Stephen Barry Guntrip

Stephen Barry Guntrip has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160339027
    Abstract: A pharmaceutical formulation comprising the compound of formula
    Type: Application
    Filed: August 3, 2016
    Publication date: November 24, 2016
    Applicant: NOVARTIS AG
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Karen Elizabeth Lackey, Stephen Barry Guntrip, Kathryn Jane Smith
  • Publication number: 20160051551
    Abstract: A pharmaceutical formulation comprising the compound of formula
    Type: Application
    Filed: October 20, 2015
    Publication date: February 25, 2016
    Applicant: NOVARTIS AG
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Karen Elizabeth Lackey, Stephen Barry Guntrip, Kathryn Jane Smith
  • Publication number: 20100120804
    Abstract: A process for the preparation of a compound of formula (I) comprising the steps: (a) reacting a compound of formula (II) wherein L and L? are suitable leaving groups, with a compound of formula (III) UNH2 ??(III) to prepare a compound of formula (IV) and subsequently (b) substituting the group R1 by replacement of the leaving group L?.
    Type: Application
    Filed: January 22, 2010
    Publication date: May 13, 2010
    Inventors: Malcom Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith
  • Publication number: 20090312325
    Abstract: There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
    Type: Application
    Filed: May 29, 2009
    Publication date: December 17, 2009
    Inventors: Ian Robert Baldwin, Michael David Barker, Anthony William Dean, Colin David Eldred, Brian Evans, Sharon Lisa Gough, Stephen Barry Guntrip, Julie Nicole Hamblin, Stuart Holman, Paul Jones, Mika Kristian Lindvall, Christopher James Lunniss, Tracy Jane Redfern, Alison Judith Redgrave, John Edward Robinson, Michael Woodrow
  • Patent number: 7566786
    Abstract: There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
    Type: Grant
    Filed: May 19, 2004
    Date of Patent: July 28, 2009
    Assignee: Glaxo Group Limited
    Inventors: Ian Robert Baldwin, Michael David Barker, Anthony William Dean, Colin David Eldred, Brian Evans, Sharon Lisa Gough, Stephen Barry Guntrip, Julie Nicole Hamblin, Stuart Holman, Paul Jones, Mika Kristian Lindvall, Christopher James Lunniss, Tracy Jane Redfern, Alison Judith Redgrave, John Edward Robinson, Michael Woodrow
  • Patent number: 7442836
    Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: October 28, 2008
    Assignee: Glaxo Group Limited
    Inventors: Keith Biggadike, Diane Mary Coe, Dean David Edney, Stephen Barry Guntrip, Abigail Halton, Brian Edgar Looker, Michael John Monteith, Rebecca Jane Moore, Rajnikant Patel, Panayiotis Alexandrou Procopiou
  • Patent number: 7442837
    Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: October 28, 2008
    Assignee: Glaxo Group Limited
    Inventors: Keith Biggadike, Diane Mary Coe, Dean David Edney, Stephen Barry Guntrip, Abigail Halton, Brian Edgar Looker, Michael John Monteith, Rebecca Jane Moore, Rajnikant Patel, Panayiotis Alexandrou Procopiou
  • Patent number: 7442719
    Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: October 28, 2008
    Assignee: Glaxo Group Limited
    Inventors: Keith Biggadike, Diane Mary Coe, Dean David Edney, Stephen Barry Guntrip, Abigail Halton, Brian Edgar Looker, Michael John Monteith, Rebecca Jane Moore, Rajnikant Patel, Panayiotis Alexandrou Procopiou
  • Patent number: 7442839
    Abstract: The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: October 28, 2008
    Assignee: Glaxo Group Limited
    Inventors: Alan Michael Chapman, Stephen Barry Guntrip, Brian Edgar Looker, Panayiotis Alexandrou Procopiou
  • Patent number: 7135600
    Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: November 14, 2006
    Assignee: Glaxo Group Limited
    Inventors: Keith Biggadike, Diane Mary Coe, Stephen Barry Guntrip, Brian Edgar Looker, Panayiotis Alexandrou Procopiou
  • Patent number: 7109333
    Abstract: A process for the preparation of a compound of formula (I) comprising the steps: (a) reacting a compound of formula (II) ?wherein L and L? are suitable leaving groups, with a compound of formula (III) UNH2??(III) to prepare a compound of formula (IV) and subsequently (b) substituting the group R1 by replacement of the leaving group L?.
    Type: Grant
    Filed: February 3, 2005
    Date of Patent: September 19, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith
  • Patent number: 7045658
    Abstract: The present invention relates to novel compounds of formula (I), to a process for their menufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: May 16, 2006
    Assignee: Glaxo Group Limited
    Inventors: Keith Biggadike, Rita Field, Stephen Barry Guntrip, Brian Edgar Looker
  • Patent number: 6828320
    Abstract: Substituted heteroaromatic compounds, and in particular substituted quinolines and quinazolines, are protein tyrosine kinase inhibitors. The compounds are described as are methods for their preparation, pharmaceutical compositions including such compounds and their use in medicine, for example in the treatment of cancer and psoriasis.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: December 7, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: George Stuart Cockerill, Malcolm Clive Carter, Stephen Barry Guntrip, Kathryn Jane Smith
  • Publication number: 20040180876
    Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Application
    Filed: February 9, 2004
    Publication date: September 16, 2004
    Inventors: Keith Biggadike, Diane Mary Coe, Dean David Edney, Stephen Barry Guntrip, Abigail Halton, Brian Edgar Looker, Michael John Monteith, Rajnikant Patel, Panayiotis Alexandrou Procopiou
  • Publication number: 20040157830
    Abstract: The present invention relates to novel compounds of formula (I), to a process for their menufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Application
    Filed: March 5, 2004
    Publication date: August 12, 2004
    Inventors: Keith Biggadike, Rita Field, Stephen Barry Guntrip, Brian Edgar Looker
  • Patent number: 6727256
    Abstract: Substituted heteroaromatic compounds of formula (I), wherein X is N or CH; Y is CR1 and V is N; or Y is N and V is CR1; or Y is CR1 and V is CR2; or Y is CR2 and V is CR1; R1 represents a group CH3SO2CH2CH2NHCH2—Ar—, wherein Ar is selected from phenyl, furan, thiophene, pyrrole and thiazole, each of which may optionally be substituted by one or two halo, C1-4alkyl or C1-4alkoxy groups; R2 is selected from the group comprising hydrogen, halo, hydroxy, C1-4alkyl, C1-4alkoxy, C1-4alkylamino and di[C1-4alkyl]amino; U represents a phenyl, pyridyl, 3H-imidazolyl, indolyl, isoindolyl, indolinyl, isoindolinyl, 1H-indazolyl, 2,3-dihydro-1H-indazolyl, 1H-benzimidazolyl, 2,3-dihydro-1H-benzimidazolyl or 1H-benzotriazolyl group, substituted by an R3 group and optionally substituted by at least one independently selected R4 group; R3 is selected from a group comprising benzyl, halo-, dihalo- and trihalobenzyl, benzoyl, pyridylmethyl, pyridylmethoxy, phenoxy, benzyloxy, halo-, dihalo- and trihalobenzy
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: April 27, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith
  • Patent number: 6723726
    Abstract: Substituted heteroaromatic compounds, and in particular substituted bicyclic heteroaromatic compounds of formula (I), wherein X is N or CH; A represents a fused 5, 6 or 7-membered heterocyclic ring containing 1 to 5 heteroatoms which may be the same or different and which are selected from N, O or S(O)m, wherein m is as defined above, the heterocyclic ring containing a total of 1, 2 or 3 double bonds inclusive of the bond in the pyridine or pyrimidine ring to which it is fused, with the provisos that the heterocyclic ring does not form part of a purine and that the fused heterocyclic ring does not contain two adjacent O or S(O)m atoms.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: April 20, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: George Stuart Cockerill, Malcolm Clive Carter, Stephen Barry Guntrip, Kathryn Jane Smith
  • Patent number: 6713485
    Abstract: The present invention relates to substituted heteroaromatic compounds, methods for their preparation, pharmaceutical compositions containing them and their use in medicine. Specifically, the invention relates to quinazoline derivatives useful in treating disorders mediated by protein tyrosine kinase activity, in particular erbB-2 and/or EGFR activity.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: March 30, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith
  • Publication number: 20030176451
    Abstract: A process for the preparation of a compound of formula (I) 1
    Type: Application
    Filed: January 15, 2003
    Publication date: September 18, 2003
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith
  • Publication number: 20020147205
    Abstract: The present invention relates to substituted heteroaromatic compounds, methods for their preparation, pharmaceutical compositions containing them and their use in medicine. Specifically, the invention relates to quinazoline derivatives useful in treating disorders mediated by protein tyrosine kinase activity, in particular erbB-2 and/or EGFR activity.
    Type: Application
    Filed: February 8, 2002
    Publication date: October 10, 2002
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith