Patents by Inventor Stephen M. Condon

Stephen M. Condon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMAC mimetic
    Patent number: 11951147
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Grant
    Filed: May 3, 2022
    Date of Patent: April 9, 2024
    Assignee: MEDIVIR AB
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • SULFONYL UREA NLRP3 INFLAMMASOME INHIBITORS
    Publication number: 20240018166
    Abstract: Disclosed herein are NLRP3 inflammasome inhibitors and compositions thereof. Also disclosed herein are methods including administering a therapeutically effective amount of a composition comprising at least one NLRP3 inflammasome inhibitor to a subject in need thereof.
    Type: Application
    Filed: November 23, 2021
    Publication date: January 18, 2024
    Inventors: Bin LIU, Jiangchao YAO, Thomas HAIMOWITZ, Christopher BENETATOS, Stephen M. CONDON, Steven A. BOYD
  • ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS
    Publication number: 20230233593
    Abstract: Described herein are orally-bioavailable nucleoside analogs and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of coronavirus infections, including SARS-CoV-2 infection.
    Type: Application
    Filed: January 25, 2023
    Publication date: July 27, 2023
    Inventors: Christopher J. BURNS, Glen COBURN, Guo-Hua CHU, Stephen M. CONDON, Steven A. BOYD, Daniel C. PEVEAR
  • SMAC MIMETIC
    Publication number: 20230149500
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Application
    Filed: May 3, 2022
    Publication date: May 18, 2023
    Inventors: Stephen M. CONDON, Yijun DENG, Matthew G. LAPORTE, Susan R. RIPPIN
  • Orally-bioavailable nucleoside analogs
    Patent number: 11638715
    Abstract: Described herein are orally-bioavailable nucleoside analogs and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of coronavirus infections, including SARS-CoV-2 infection.
    Type: Grant
    Filed: June 16, 2022
    Date of Patent: May 2, 2023
    Assignee: VENATORX PHARMACEUTICALS, INC.
    Inventors: Christopher J. Burns, Glen Coburn, Guo-Hua Chu, Stephen M. Condon, Steven A. Boyd, Daniel C. Pevear
  • HEPATITIS B CAPSID ASSEMBLY MODULATORS
    Publication number: 20230127898
    Abstract: Described herein are hepatitis B capsid assembly modulator compounds of formula (I) and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: March 3, 2021
    Publication date: April 27, 2023
    Inventors: Jiangchao YAO, Glen COBURN, Bin LIU, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • BROAD-SPECTRUM CARBAPENEMS
    Publication number: 20230127944
    Abstract: The present disclosure provides broad-spectrum carbapenem derivatives and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such derivatives and/or compositions.
    Type: Application
    Filed: September 17, 2020
    Publication date: April 27, 2023
    Inventors: Christopher J. BURNS, Guo-Hua CHU, Jodie HAMRICK, Steven A. BOYD, Stephen M. CONDON
  • PENICILLIN-BINDING PROTEIN INHIBITORS
    Publication number: 20230114728
    Abstract: Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
    Type: Application
    Filed: September 24, 2020
    Publication date: April 13, 2023
    Inventors: Christopher J. BURNS, Denis DAIGLE, Guo-Hua CHU, Jodie HAMRICK, Steven A. BOYD, Allison L. ZULLI, Stephen M. CONDON, Cullen L. MYERS, Zhenrong XU, Tsuyoshi Uehara, Nathan LINE
  • HEPATITIS B CAPSID ASSEMBLY MODULATORS
    Publication number: 20230107941
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: December 9, 2020
    Publication date: April 6, 2023
    Inventors: Christopher J. BURNS, Glen COBURN, Bin LIU, Jiangchao YAO, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • HEPATITIS B CAPSID ASSEMBLY MODULATORS
    Publication number: 20230062975
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: September 19, 2022
    Publication date: March 2, 2023
    Inventors: Christopher J. BURNS, Glen COBURN, Bin LIU, Jiangchao YAO, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • Hepatitis B capsid assembly modulators
    Patent number: 11566001
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: January 31, 2023
    Assignee: VENATORX PHARMACEUTICALS, INC.
    Inventors: Christopher J. Burns, Glen Coburn, Bin Liu, Jiangchao Yao, Christopher Benetatos, Steven A. Boyd, Stephen M. Condon, Thomas Haimowitz
  • ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS
    Publication number: 20230024722
    Abstract: Described herein are orally-bioavailable nucleoside analogs and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of coronavirus infections, including SARS-CoV-2 infection.
    Type: Application
    Filed: June 16, 2022
    Publication date: January 26, 2023
    Inventors: Christopher J. BURNS, Glen COBURN, Guo-Hua CHU, Stephen M. CONDON, Steven A. BOYD, Daniel C. PEVEAR
  • HEPATITIS B CAPSID ASSEMBLY MODULATORS
    Publication number: 20220298110
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Application
    Filed: October 29, 2021
    Publication date: September 22, 2022
    Inventors: Christopher J. BURNS, Glen COBURN, Bin LIU, Jiangchao YAO, Christopher BENETATOS, Steven A. BOYD, Stephen M. CONDON, Thomas HAIMOWITZ
  • SOLID FORMS OF AN ORALLY-DELIVERED BETA-LACTAMASE INHIBITOR AND USES THEREOF
    Publication number: 20220194964
    Abstract: Disclosed herein are crystalline forms of ((2-Ethylbutanoyl)oxy)methyl (R)-2-hydroxy-3-propionamido-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylate. Also disclosed herein are methods of treating a bacterial with a crystalline form of ((2-Ethylbutanoyl)oxy)methyl (R)-2-hydroxy-3-propionamido-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylate.
    Type: Application
    Filed: April 1, 2020
    Publication date: June 23, 2022
    Inventors: Christopher J. BURNS, Lawrence ROSEN, Stephen M. CONDON, Eugen F. MESAROS, Allison L. ZULLI, Robert E. Lee TROUT, Yijun DENG, Steven A. BOYD, Robert SIMPSON
  • SMAC mimetic
    Patent number: 11351221
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: June 7, 2022
    Assignee: MEDIVIR AB
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • Penicillin-binding protein inhibitors
    Patent number: 11332485
    Abstract: Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: May 17, 2022
    Assignee: VENATORX PHARMACEUTICALS, INC.
    Inventors: Christopher J. Burns, Denis Daigle, Guo-Hua Chu, Jodie Hamrick, Matthew Lucas, Steven A. Boyd, Allison L. Zulli, Eugen F. Mesaros, Stephen M. Condon, Robert E. Lee Trout, Cullen L. Myers
  • COMBINATION COMPOSITIONS COMPRISING A BETA-LACTAMASE INHIBITOR AND USES THEREOF
    Publication number: 20220125812
    Abstract: The present invention relates to pharmaceutical compositions containing boron-containing compounds and their use as inhibitors of beta-lactamase enzymes and as antibacterial agents in combination with a beta-lactam antibiotic.
    Type: Application
    Filed: November 22, 2019
    Publication date: April 28, 2022
    Inventors: Christopher J. BURNS, Denis DAIGLE, Jodie HAMRICK, Daniel C. PEVEAR, Robert E. Lee TROUT, Luigi XERRI, Timothy HENKEL, Cullen L. MYERS, Stephen M. CONDON, Anthony DRAGER, Lawrence ROSEN
  • Hepatitis B capsid assembly modulators
    Patent number: 11247965
    Abstract: Described herein are hepatitis B capsid assembly modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of hepatitis B.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: February 15, 2022
    Assignee: VENATORX PHARMACEUTICALS, INC.
    Inventors: Christopher J. Burns, Glen Coburn, Bin Liu, Jiangchao Yao, Christopher Benetatos, Steven A. Boyd, Stephen M. Condon
  • PENICILLIN-BINDING PROTEIN INHIBITORS
    Publication number: 20210198288
    Abstract: Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.
    Type: Application
    Filed: May 23, 2019
    Publication date: July 1, 2021
    Inventors: Christopher J. BURNS, Denis DAIGLE, Guo-Hua CHU, Jodie HAMRICK, Steven A. BOYD, Allison L. ZULLI, Eugen F. MESAROS, Stephen M. CONDON, Robert E. Lee TROUT, Cullen L. MYERS, Zhenrong XU
  • BROAD-SPECTRUM CARBAPENEMS
    Publication number: 20210188851
    Abstract: The present disclosure provides broad-spectrum carbapenem derivatives and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such derivatives and/or compositions.
    Type: Application
    Filed: May 29, 2019
    Publication date: June 24, 2021
    Inventors: Christopher J. BURNS, Guo-Hua CHU, Jodie HAMRICK, Steven A. Boyd, Stephen M. CONDON