Patents by Inventor Stephen Robert Parker

Stephen Robert Parker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11073451
    Abstract: Methods of treating an inert surface of a substrate to improve the adherence to the treated surface of micro-dimensioned particles including the steps of: contacting the inert surface with in an aqueous dispersion of a construct of the structure F-S-L; and then washing the surface with an aqueous vehicle to provide the treated surface, where F is a polyamine; S is —CO(CH2)2CO—, —CO(CH2)3CO—, —CO(CH2)4CO— or —CO(CH2)5CO—; and L is a diacyl- or dialkyl-glycerophospholipid.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: July 27, 2021
    Assignee: KODE BIOTECH LIMITED
    Inventors: Stephen Micheal Henry, Stephen Robert Parker, Nicolai Vladimirovich Bovin, Igor Leonidovich Rodionov
  • Patent number: 10408717
    Abstract: Method of localizing cells to at least one discrete area on a surface of a substrate by propelling droplets of an aqueous dispersion of a synthetic construct of the structure F-S-L from a plurality of orifices located in a print head of an inkjet printer onto the surface. In the structure F-S-L, F is a functional moiety capable of associating with the cells by direct or indirect non-covalent interaction with biotin or an epitope of an antigen presented at the surface of the cells, S is a spacer selected to provide a construct that is dispersible in water at a temperature of 25° C. in the absence of organic solvents or detergents, and L is a diacyl- or dialkyl lipid.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: September 10, 2019
    Inventors: Nicolai Vladimirovich Bovin, Stephen Micheal Henry, Stephen Robert Parker
  • Publication number: 20190195759
    Abstract: Methods of treating an inert surface of a substrate to improve the adherence to the treated surface of micro-dimensioned particles including the steps of: contacting the inert surface with in an aqueous dispersion of a construct of the structure F-S-L; and then washing the surface with an aqueous vehicle to provide the treated surface, where F is a polyamine; S is —CO(CH2)2CO—, —CO(CH2)3CO—, —CO(CH2)4CO— or —CO(CH2)5CO—; and L is a diacyl- or dialkyl-glycerophospholipid.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 27, 2019
    Inventors: Stephen Micheal HENRY, Stephen Robert PARKER, Nicolai Vladimirovich BOVIN, Igor Leonidovich RODIONOV
  • Patent number: 10215672
    Abstract: Biocompatible methods of functionalizing inert surfaces for use in biological applications are described. The methods employ the use of synthetic constructs of the generic structure F-S-L (where F is a functional moiety, S is a spacer selected to provide a construct that is dispersible in water, and L is a diacyl- or dialkyl-glycerophospholipid). An object of the invention is to localize or immobilize functional moieties to the inert surface of a substrate wherein the surface is comprised of glass, silver, polyamide, polycarbonate, polypropylene, polyethersulfone, polytetrafluoroethylene or polyvinylidene fluoride, and the substrate is comprised of a fiber, membrane, microsphere or nanosphere.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: February 26, 2019
    Assignee: KODE BIOTECH LIMITED
    Inventors: Stephen Micheal Henry, Stephen Robert Parker
  • Publication number: 20190003938
    Abstract: Method of localizing cells to at least one discrete area on a surface of a substrate by propelling droplets of an aqueous dispersion of a synthetic construct of the structure F-S-L from a plurality of orifices located in a print head of an inkjet printer onto the surface. In the structure F-S-L, F is a functional moiety capable of associating with the cells by direct or indirect non-covalent interaction with biotin or an epitope of an antigen presented at the surface of the cells, S is a spacer selected to provide a construct that is dispersible in water at a temperature of 25° C. in the absence of organic solvents or detergents, and L is a diacyl- or dialkyl lipid.
    Type: Application
    Filed: April 16, 2018
    Publication date: January 3, 2019
    Inventors: Nicolai Vladimirovich BOVIN, Stephen Micheal HENRY, Stephen Robert PARKER
  • Patent number: 9970928
    Abstract: Method of localizing a functional moiety (F) to at least one discrete area on a surface of a substrate, by propelling droplets of an aqueous dispersion of a synthetic construct of the structure F-S-L from a plurality of orifices located in a print head of an inkjet printer onto the surface. In the structure F-S-L, S is a spacer selected to provide a construct that is dispersible in water at a temperature of 25° C. in the absence of organic solvents or detergents, L is a diacyl- or dialkyl lipid and the at least one discrete area is in the shape of a symbol readable by optical character recognition (OCR) apparatus or a pattern having a combination of indicia in which the synthetic construct is present at different densities.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: May 15, 2018
    Inventors: Nicolai Vladimirovich Bovin, Stephen Micheal Henry, Stephen Robert Parker
  • Publication number: 20170219467
    Abstract: Biocompatible methods of functionalising inert surfaces for use in biological applications are described. The methods employ the use of synthetic constructs of the generic structure F-S-L (where F is a functional moiety, S is a spacer selected to provide a construct that is dispersible in water, and L is a diacyl- or dialkyl-glycerophospholipid). An object of the invention is to localise or immobilise functional moieties to the inert surface of a substrate wherein the surface is comprised of glass, silver, polyamide, polycarbonate, polypropylene, polyethersulfone, polytetrafluoroethylene or polyvinylidene fluoride, and the substrate is comprised of a fibre, membrane, microsphere or nanosphere.
    Type: Application
    Filed: November 29, 2016
    Publication date: August 3, 2017
    Inventors: Stephen Micheal Henry, Stephen Robert PARKER
  • Patent number: 9528139
    Abstract: Method of functionalizing microspheres comprising immersing the microspheres in an aqueous dispersion of a construct of the structure F-S-L; and then washing the microspheres with an aqueous vehicle to provide the functionalized microspheres. The construct is of the structure: where F is a functional moiety, M is a monovalent cation, R1 and R2 are independently a C14-20 acyl, alkyl or alkenyl group, and S is a spacer selected to provide a construct that is dispersible in water.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: December 27, 2016
    Inventors: Stephen Micheal Henry, Stephen Robert Parker
  • Publication number: 20140370538
    Abstract: Biocompatible methods of functionalising inert surfaces for use in biological applications are described. The methods employ the use of synthetic constructs of the generic structure F-S-L (where F is a functional moiety, S is a spacer selected to provide a construct that is dispersible in water, and L is a diacyl- or dialkyl-glycerophospholipid). An object of the invention is to localise or immobilise functional moieties to the inert surface of a substrate wherein the surface is comprised of glass, silver, polyamide, polycarbonate, polypropylene, polyethersulfone, polytetrafluoroethylene or polyvinylidene fluoride, and the substrate is comprised of a fibre, membrane, microsphere or nanosphere.
    Type: Application
    Filed: December 19, 2012
    Publication date: December 18, 2014
    Inventors: Stephen Micheal Henry, Stephen Robert Parker
  • Publication number: 20140004499
    Abstract: The invention relates to methods of localizing biofunctional moieties (F) to surfaces and synthetic constructs of the general structure F-S-S? for use in such methods. F is the biofunctional moiety, S is a spacer covalently linking F to S?, and S? is sterol. In particular, the invention relates to the preparation of biofunctional surfaces and surface modified biological structures including cells (kodecytes), enveloped viruses (kodevirions) and liposomes or virosomes (kodesomes).
    Type: Application
    Filed: January 6, 2012
    Publication date: January 2, 2014
    Inventors: Nicolai Vladimirovich Bovin, Andrey Alfredovich Formanovsky, Stephen Micheal Henry, Stephen Robert Parker, Inna Stanislavovna Popova
  • Publication number: 20120184461
    Abstract: Methods of manufacturing cards, strips and multiwell plates for use in diagnostic assays are described. The methods employ the use of synthetic constructs of the generic structure F-S-L (where F is an antigen for a reactive antibody, S is a spacer covalently linking F to L, and L is a lipid) as “ink” in inkjet printers. The cards, strips and multiwell plates provide a number of advantages including efficiency of manufacture and improved accuracy in determining and recording assay results.
    Type: Application
    Filed: June 29, 2010
    Publication date: July 19, 2012
    Inventors: Nicolai Vladimirovich Bovin, Stephen Micheal Henry, Stephen Robert Parker
  • Patent number: 6060507
    Abstract: Massoialactone is useful for preventing or at least inhibiting growth of a fungus. Accordingly, a fungicidal composition has massoialactone as an active antifungal compound together with an agronomically acceptable carrier therefor. Additional antifungal ingredients can be added to the composition. The composition can be applied to surfaces, including surfaces of plants and plant parts, such as seeds.
    Type: Grant
    Filed: August 28, 1997
    Date of Patent: May 9, 2000
    Assignee: Horticulture and Food Research Institute of New Zealand Limited
    Inventors: Robert Anthony Hill, Horace G. Cutler, Stephen Robert Parker