Abstract: Characterization of proteins and/or protein complexes using covalent labeling denaturation methodology are described.

Abstract: A solid production system for producing a solid on demand is provided herein. In some aspects, the solid-production system includes a solid ejector arranged to loosen a solid in each of one or more fluid molds indexed into an ejection position relative to the solid ejector, the one or more fluid molds including a bottom surface and side surfaces extending therefrom, wherein the solid ejector is actuatable so as to be urged into contact with and to apply pressure to at least one of the side surfaces of the fluid mold indexed into the ejection position so as to loosen the solid within the fluid mold in preparation for dispensing the solid from the fluid mold.

Abstract: A solid-production system for producing a solid on demand is disclosed herein. In some aspects, the solid-production system includes a cooling block arranged to interact with one or more fluid molds to reduce a first temperature of a fluid dispensed in each of the one or more fluid molds to a second temperature, the second temperature being lower than the first temperature, to solidify the fluid in each of the one or more fluid molds; wherein the cooling block has a thermal mass operable to absorb and store thermal energy transferred by the fluid in each of the one or more fluid molds so as to reduce the first temperature of the fluid to the second temperature.

Abstract: A solid-production system for producing a solid on demand is provided herein. In some aspects, the solid-production system includes a conveying mechanism; a fluid-dispensing mechanism; a pressure plate arranged to urge the fluid mold into interaction with a cooling block to form a solid; a solid-dispensing mechanism arranged to dispense the solid loosened by a solid ejector to a user; and processing circuitry configured to implement a master state machine, and slave state machines for respective ones of the fluid-dispensing mechanism, conveying mechanism, pressure plate and solid-dispensing mechanism, wherein the master state machine is configured to send commands to the slave state machines based on states of the slave state machines, and the slave state machines are configured to execute the commands to control the respective ones of the conveying mechanism, fluid-dispensing mechanism, pressure plate, and solid-dispensing mechanism.

Abstract: A system includes at least a computing apparatus including a communication interface coupled or coupleable to a sensor in contact with a heatable liquid contained in a vessel, the sensor being configured to obtain measurements of a property of the liquid or the sensor; and a processor coupled to the communication interface and configured to receive the measurements of the property of the liquid or the sensor. The processor is programmed to at least determine a height of the liquid in the vessel, and in at least one instance oscillation of the height of the liquid in the vessel, from the measurements, determine an amplitude of the oscillation, determine a level of boil of the liquid from the amplitude of the oscillation and a viscosity of the liquid, and output an indication of the level of boil for display or control of the heat to which the liquid is subjected.

Abstract: Disclosed herein are electronic devices having a deformable surfaces through which a user can provide inputs to the device by applying a force such as a pinch or a squeeze. A particular embodiment is an earpiece with the deformable surface part of an elongate section extending from an earbud. The deformable surface includes an incompressible hyperelastic material and a pressure sensor. The pressure sensor includes a pressure sensing element and a void defined between the pressure sensing element and the incompressible hyperelastic material. An applied force is transferred by the incompressible hyperelastic material to compress the void and change an internal pressure thereof. The changed pressure is detected by the pressure sensor, and can result in changed operation of the electronic device.

Abstract: A transparent force sensor for detecting an applied force on a surface of a device. The transparent force sensor includes a transparent force-sensitive film having an array of strain-relief features oriented along a first direction. The transparent force-sensitive film is formed from a transparent piezoelectric material that exhibits a substantially reduced net charge when strained along a primary direction. The force sensor also includes a display element disposed on one side of the transparent force-sensitive film.

Abstract: A wireless power transmitting device transmits wireless power signals to a wireless power receiving device. The wireless power receiving device has a rectifier and a wireless power receiving coil that receives wireless power signals. The wireless power transmitting device uses a layer of coils to transmit the wireless power signals. A dielectric layer in the wireless power transmitting device defines a charging surface that receives the wireless power receiving device. A layer of temperature sensors is interposed between the layer of coils and the dielectric layer. Control circuitry in the wireless power transmitting device uses temperature information from the temperature sensors to determine whether a foreign object such as a coin is present on the charging surface.

Abstract: Specific binding members directed to eotaxin-1, in particular human antibodies and antibody fragments against human eotaxin-1 and especially those which neutralise eotaxin-1 activity. The antibodies VH and/or VL domain of the scFv fragment herein termed CAT-212 and of the IgG4 antibody herein termed CAT 213. One or more complementary determining regions (CDRs) of the CAT-213/-213 VH and/or VL domains especially VH CRD3 in other antibody framework regions. Compositions containing specific binding members and their use in methods of inhibiting or neutralising eotaxin, including methods of treatment or the human or animal body by therapy.

Abstract: A method of determining an absorption or turbidity coefficient of a liquid involves storing a set of data describing a plurality of droplets or other discrete bodies of liquid of different shapes, sizes and absorption or turbidity coefficients. Each body is captured as a combination of a measurable transmission parameter obtained by modelling the interaction of light with a drop, and of one or more dimensional measurements selected from lengths, areas and volumes. The absorption or turbidity coefficient is indicated also. By measuring the transmission of light through a real body of liquid, and making measurements allowing the droplet to be specified, the absorption or turbidity coefficient associated with a droplet giving rise to the same behaviour in transmitting light can be identified from the data set.

Abstract: Automated isothermal titration micro calorimetry (ITC) system comprising a micro calorimeter with a sample cell and a reference cell, the sample cell is accessible via a sample cell stem and the reference cell is accessible via a reference cell stem. The system further comprises an automatic pipette assembly comprising a syringe with a titration needle arranged to be inserted into the sample cell for supplying titrant, the pipette assembly comprises an activator for driving a plunger in the syringe, a pipette translation unit supporting the pipette assembly and being arranged to place pipette in position for titration, washing and filling operations, a wash station for the titrant needle, and a cell preparation unit arranged to perform operations for replacing the sample liquid in the sample cell when the pipette is placed in another position than the position for titration.

Abstract: Methods and systems relate to determining sensory motor performance based on user non-postural movements within a generated dynamic virtual environment. The generated environment requires users to: (i) utilize primary sensor inputs (e.g., vision, vestibular sensation and somatosensation); (ii) assess the dynamic virtual environment; and (iii) integrate and translate those inputs into movement to control the dynamic virtual environment. The methods may include receiving non-postural user input with respect to a state of one or more attributes of a dynamic virtual environment provided on a user interface for one or more sessions, the one or more attributes including a control object and a target which moves with respect to the control object; determining performance information based on the user input and the state of the one or more attributes for the one or more sessions; and determining sensory motor performance information from the performance information.

Abstract: A wireless power transmitting device transmits wireless power signals to a wireless power receiving device. To detect foreign objects, the wireless power transmitting device has an array of temperature sensors. The array of temperature sensors may include temperature sensor components such as temperature sensitive thin-film resistors or other temperature sensitive components. A temperature sensor may have thin-film resistors formed on opposing sides of a substrate. The thin-film resistors may be formed from meandered metal traces to reduce eddy current formation during operation of the wireless power transmitting device. Signal paths coupling control circuitry on the wireless power transmitting device to the array of temperature sensors may be configured to extend along columns of the temperature sensors without running along each row of the temperature sensors, thereby reducing eddy currents from loops of signal routing lines.

Abstract: Embodiments are disclosed for a feature-based simultaneous localization and mapping (SLAM) system and method that generates radio maps for environments that are not accessible for surveying. More accurate radio maps are generated for an unsurveyed environment by determining a best estimate of a mobile device state from harvested traced data that maximizes a posterior probability of the mobile device state given measurements, landmarks and loop constraints.

Abstract: Embodiments are disclosed for a feature-based simultaneous localization and mapping (SLAM) system and method that generates radio maps for environments that are not accessible for surveying. More accurate radio maps are generated for an unsurveyed environment by determining a best estimate of a mobile device state from harvested traced data that maximizes a posterior probability of the mobile device state given measurements, landmarks and loop constraints.

Abstract: A mobile communication device includes a housing defining an interior volume and a port connecting the interior volume to an environment exterior to the device. The mobile communication device also includes a display viewable through a surface of the housing, a pressure sensor configured to measure an air pressure within the interior volume, an air flow sensor configured to measure an air flow through the port, and a processor. The processor is configured to determine an amount of force applied to the housing using a measurement of the air pressure by the pressure sensor and a measurement of the air flow by the air flow sensor.

Abstract: A device configured to sense a touch on a surface of the device. The device includes a cover and a force-sensing structure disposed below the cover. The force-sensing structure may be positioned below a display and used in combination with other force-sensing elements to estimate the force of a touch on the cover of a device.

Abstract: Conventional UPVC windows have casements which are pivotable and movable in a limited manner relative to the frame. It is desirable to be to move all the casements such that substantially the entire the frame is opened.