Patents by Inventor Stephen Terence Dunne

Stephen Terence Dunne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210268213
    Abstract: A cartridge for a dispensing device, such as a nebulizer, for dispensing a medicament composed of or produced from a plurality of components and a system including a dispensing device, such as a nebulizer, and such a cartridge. The cartridge includes at least two fluidically separated chambers which each contain at least one component of the medicament, an actuating mechanism for fluidically connecting the chambers and mixing the components for the dispensing of the medicament A method for preparing a medicament composed of a plurality of components in a cartridge for the dispensing of said medicament by way of a dispensing device, such as a nebulizer, where a plurality of fluidically separated chambers of the cartridge are fluidically connected, and a component of the medicament is at least partially transferred from one of the chambers to another of the chambers with another component of the medicament in order to mix the components.
    Type: Application
    Filed: June 12, 2019
    Publication date: September 2, 2021
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Andree JUNG, Stephen Terence DUNNE, Joachim Carl Herbert EICHER
  • Publication number: 20210228822
    Abstract: A system includes a nebulizer for nebulizing a fluid from a container and such a container containing a fluid and are proposed. The fluid is a non-newtonian fluid, in form of a suspension or emulsion or a liposomal fluid or a gel. The nebulizer includes a fluid pump for withdrawing the fluid in doses from the container and pressurizing the respective doses for nebulization through nozzle channels having a hydraulic diameter in the range of 3 to 20 microns at an operational pressure of 5 to 250 MPa.
    Type: Application
    Filed: May 3, 2019
    Publication date: July 29, 2021
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Stephen Terence DUNNE, Dana HUESCH, Peter Rolf Werner LANGGUTH
  • Publication number: 20200009333
    Abstract: A nebulizer for nebulizing a fluid from a cartridge and a cartridge for such a nebulizer is proposed. The cartridge comprises a container containing the fluid to be nebulized and is fluidically connected to the nebulizer by inserting a connecting element of the nebulizer for conveying the fluid out of the container. The cartridge is preferably adapted to sealingly receive the connecting element and can optionally comprise a membrane or sealing wall which seals the cartridge initially and is piercable or breakable by the connecting element upon insertion. The cartridge can further comprise an at least partially flexible and/or bendable tube for conveying the fluid out of the container. The tube is preferably wettable with the fluid and/or comprises an at least partially hydrophilic and/or polar surface. Further, the tube can at least partially be shaped as a helix.
    Type: Application
    Filed: December 21, 2017
    Publication date: January 9, 2020
    Applicant: Boehringer lngelheim International GmbH
    Inventors: Stephen Terence DUNNE, Joachim Carl Herbert EICHER, Herbert GRAESSL, Andree JUNG, Gilbert WUTTKE
  • Patent number: 10500355
    Abstract: The invention relates to a system composed of an inhaler and a capsule, preferably intended for single use. The capsule contains a preferably powdered pharmaceutical preparation which, for inhalation, is expelled from the capsule through at least one hole. The capsule comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. The prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pulling mechanism. Prior to this the hole is closed off by a capsule receptacle or a film. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed. Also shown is an inhaler suitable as a disposable product, which is manufactured from thermoformed parts or from blister film.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: December 10, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Holger Holakovsky, Jessica Frentzel-Beyme, Stephen Terence Dunne, Jens Besseler, Claudius Weiler
  • Patent number: 10220165
    Abstract: The invention relates to a capsule for receiving a preferably powdered pharmaceutical preparation and an inhaler in which, for inhalation, the preparation is expelled from the capsule through at least one hole. A capsule according to the invention comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. Systems according to the invention comprising inhalers and capsules are described, in which the prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pushing or pulling mechanism. Prior to this the hole is closed off by part of the capsule itself or by a capsule receptacle belonging to the inhaler. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed.
    Type: Grant
    Filed: May 21, 2012
    Date of Patent: March 5, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Stephen Terence Dunne, Jens Besseler, Jessica Frentzel-Beyme, Holger Holakovsky, Heinrich Kladders, Claudius Weiler, Ole Zumblick
  • Publication number: 20180243519
    Abstract: Disclosed is an inhaler and a method for using the inhaler for the inhalation of a formulation from a carrier. The carrier contains the formulation in a receptacle and is set oscillating by an air current. An improved or defined delivery and nebulisation of the preferably powdered formulation is made possible by the fact that the carrier is set oscillating in defined manner, the formulation is dispensed through a cover element having three to five holes and/or the air current flows onto a fin associated with the carrier and flows past at least substantially only one flat side of the carrier.
    Type: Application
    Filed: May 1, 2018
    Publication date: August 30, 2018
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Andree JUNG, Stephen Terence DUNNE
  • Patent number: 10004859
    Abstract: The invention relates to an apparatus for nebulizing preferably powdered medicinal formulations, the nebulization being assisted by propellant. According to the invention, the propellant is supplied in pulsed form to the powder cavity (1) containing the formulation, which is attached to the nozzle (3) from which the aerosol is emitted. The apparatus according to the invention provides an increase in the fraction of pulmonary particles in the aerosol leaving the nozzle (3).
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: June 26, 2018
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Robert Gerhard Winkler, Herbert Wachtel, Stephen Terence Dunne, Andree Jung
  • Patent number: 9993601
    Abstract: Disclosed is an inhaler and a method for using the inhaler for the inhalation of a formulation from a carrier. The carrier contains the formulation in a receptacle and is set oscillating by an air current. An improved or defined delivery and nebulisation of the preferably powdered formulation is made possible by the fact that the carrier is set oscillating in defined manner, the formulation is dispensed through a cover element having three to five holes and/or the air current flows onto a fin associated with the carrier and flows past at least substantially only one flat side of the carrier.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: June 12, 2018
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Andree Jung, Stephen Terence Dunne
  • Publication number: 20170203056
    Abstract: A drug delivery device (100), in particular a nebulizer or inhaler, is proposed, wherein a collapsible container (16) is combined with a mechanism (30) to help the collapsing process and to prevent the collapsed container expanding again, hence preventing forming of vapor and gas bubbles within.
    Type: Application
    Filed: July 24, 2015
    Publication date: July 20, 2017
    Applicant: Boehringer Ingelheim International GmbH
    Inventor: Stephen Terence DUNNE
  • Publication number: 20170143904
    Abstract: An injector for delivering medicament comprises a collapsible container (1002) for containing the liquid medicament, a normally-closed valve (1004) coupled to the collapsible container (1002) for retaining the liquid medicament within the collapsible container and an injection means (1006) for delivering the liquid medicament from the collapsible container. The liquid medicament is maintained under pressure by a pressurising means (1003) which pressurises the liquid medicament such that it is delivered by the injection means (1006) when the normally-closed valve (1004) is opened.
    Type: Application
    Filed: December 15, 2016
    Publication date: May 25, 2017
    Applicant: New Injection Systems Ltd
    Inventor: Stephen Terence Dunne
  • Patent number: 9550025
    Abstract: An injector for delivering medicament comprises a collapsible container (1002) for containing the liquid medicament, a normally-closed valve (1004) coupled to the collapsible container (1002) for retaining the liquid medicament within the collapsible container and an injection means (1006) for delivering the liquid medicament from the collapsible container. The liquid medicament is maintained under pressure by a pressurizing means (1003) which pressurizes the liquid medicament such that it is delivered by the injection means (1006) when the normally-closed valve (1004) is opened.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: January 24, 2017
    Assignee: NEW INJECTION SYSTEMS LTD.
    Inventor: Stephen Terence Dunne
  • Patent number: 9283335
    Abstract: A dispensing device, a storage device and a method for dispensing powder in which powder is dispensed through a duct with a flat cross section to de-agglomerate the powder and to generate a spray with fine particle size. A storage chamber for the powder may be closed by a bursting element which is burst by pressurized gas for discharging the powder, the gas pressure reaching or exceeding a peak value before the bursting element bursts so that the powder is dispensed at a lower gas pressure. The powder may be forced through the duct by a gas pressure of less than 300 kPa to de-agglomerate the powder and/or to generate the spray. The storage device can have multiple storage chambers and associated ducts or nozzles, so that each dose of powder can be dispensed through a separate duct or nozzle.
    Type: Grant
    Filed: October 6, 2005
    Date of Patent: March 15, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Stephen Terence Dunne, Marc Rohrschneider, Achim Moser
  • Patent number: 9259540
    Abstract: A nozzle, an inhaler with a nozzle and a method for producing a nozzle are proposed, which nozzle comprises two holes formed in a flat plate which plate is then deformed such that the axes of the holes intersect so that jets of fluids moving through the holes impinge with each other.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: February 16, 2016
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventor: Stephen Terence Dunne
  • Patent number: 9089658
    Abstract: A dispensing device, and a method for dispensing powder in which powder is dispensed through a duct with a flat cross section to de-agglomerate the powder and to generate a spray with fine particle size. A storage chamber for the powder may be closed by a bursting element which is burst by pressurized gas for discharging the powder, the gas pressure reaching or exceeding a peak value before the bursting element bursts so that the powder is dispensed at a lower gas pressure. The powder may be forced through the duct by a gas pressure of less than 300 kPa to de-agglomerate the powder and/or to generate the spray. The storage device can have multiple storage chambers and associated ducts or nozzles, so that each dose of powder can be dispensed through a separate duct or nozzle, the storage chamber and duct or nozzle being formed of a one-piece construction.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: July 28, 2015
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Stephen Terence Dunne, Marc Rohrschneider, Achim Moser
  • Publication number: 20150136131
    Abstract: The invention relates to a system composed of an inhaler and a capsule, preferably intended for single use. The capsule contains a preferably powdered pharmaceutical preparation which, for inhalation, is expelled from the capsule through at least one hole. The capsule comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. The prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pulling mechanism. Prior to this the hole is closed off by a capsule receptacle or a film. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed. Also shown is an inhaler suitable as a disposable product, which is manufactured from thermoformed parts or from blister film.
    Type: Application
    Filed: May 17, 2013
    Publication date: May 21, 2015
    Applicant: Boehringer Ingelheim GmbH, Corporate Patents
    Inventors: Holger Holakovsky, Jessica Frentzel-Beyme, Stephen Terence Dunne, Jens Besseler, Claudius Weiler
  • Publication number: 20150122257
    Abstract: The invention relates to an apparatus for nebulising preferably powdered medicinal formulations, the nebulisation being assisted by propellant. According to the invention, the propellant is supplied in pulsed form to the powder cavity (1) containing the formulation, which is attached to the nozzle (3) from which the aerosol is emitted. The apparatus according to the invention provides an increase in the fraction of pulmonary particles in the aerosol leaving the nozzle (3).
    Type: Application
    Filed: April 30, 2013
    Publication date: May 7, 2015
    Inventors: Robert Gerhard Winkler, Herbert Wachtel, Stephen Terence Dunne, Andree Jung
  • Publication number: 20140182587
    Abstract: The invention relates to a capsule for receiving a preferably powdered pharmaceutical preparation and an inhaler in which, for inhalation, the preparation is expelled from the capsule through at least one hole. A capsule according to the invention comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. Systems according to the invention comprising inhalers and capsules are described, in which the prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pushing or pulling mechanism. Prior to this the hole is closed off by part of the capsule itself or by a capsule receptacle belonging to the inhaler. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed.
    Type: Application
    Filed: May 21, 2012
    Publication date: July 3, 2014
    Applicant: Boehringer Ingelheim international GmbH
    Inventors: Stephen Terence Dunne, Jens Besseler, Jessica Frentzel-Beyme, Holger Holakovsky, Heinrich Kladders, Claudius Weiler, Ole Zumblick
  • Publication number: 20140083423
    Abstract: Disclosed is an inhaler and a method for using the inhaler for the inhalation of a formulation from a carrier. The carrier contains the formulation in a receptacle and is set oscillating by an air current. An improved or defined delivery and nebulisation of the preferably powdered formulation is made possible by the fact that the carrier is set oscillating in defined manner, the formulation is dispensed through a cover element having three to five holes and/or the air current flows onto a fin associated with the carrier and flows past at least substantially only one flat side of the carrier.
    Type: Application
    Filed: September 24, 2013
    Publication date: March 27, 2014
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Andree JUNG, Stephen Terence DUNNE
  • Publication number: 20140076308
    Abstract: A nozzle, an inhaler with a nozzle and a method for producing a nozzle are proposed. The nozzle comprises two holes formed in a flat plate. Then, the plate is deformed such that the axes of the holes intersect so that jets of fluids generated by the holes impinge with each other.
    Type: Application
    Filed: November 13, 2013
    Publication date: March 20, 2014
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventor: Stephen Terence DUNNE
  • Publication number: 20120222675
    Abstract: A dispensing device, and a method for dispensing powder in which powder is dispensed through a duct with a flat cross section to de-agglomerate the powder and to generate a spray with fine particle size. A storage chamber for the powder may be closed by a bursting element which is burst by pressurized gas for discharging the powder, the gas pressure reaching or exceeding a peak value before the bursting element bursts so that the powder is dispensed at a lower gas pressure. The powder may be forced through the duct by a gas pressure of less than 300 kPa to de-agglomerate the powder and/or to generate the spray. The storage device can have multiple storage chambers and associated ducts or nozzles, so that each dose of powder can be dispensed through a separate duct or nozzle, the storage chamber and duct or nozzle being formed of a one-piece construction.
    Type: Application
    Filed: May 11, 2012
    Publication date: September 6, 2012
    Applicant: Boehringer Ingeleim International GmbH
    Inventors: Stephen Terence DUNNE, Marc ROHRSCHNEIDER, Achim MOSER