Patents by Inventor Stewart R. Durell

Stewart R. Durell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100256098
    Abstract: The invention provides compounds useful in inhibiting the activity of a Wip1 protein in a cell as well as prodrugs thereof, related methods of use and compositions which include the aforesaid compounds and prodrugs thereof. The compounds comprise a ring structure having at least five functional groups bonded thereto, wherein each functional group is bonded to a different ring atom, and wherein the at least five functional groups comprise: (a) first (R1) and second (R3) moieties each comprising a phosphate group wherein these first and second moieties are separated by at least one ring atom; (b) first (R2) and second (R4) hydrophobic groups, wherein the first and second hydrophobic groups are separated by at least one ring atom, and wherein the first hydrophobic group is bonded to a ring atom located between the ring atoms to which the first (R1) and second (R2) moieties are bonded; and an amide or carboxylic acid (R5).
    Type: Application
    Filed: August 29, 2008
    Publication date: October 7, 2010
    Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Ettore Appella, Daniel Appella, Stewart R. Durell, Jeong Bang, Hiroshi Yamaguchi, Qun Xu