Patents by Inventor Subhash Annedi

Subhash Annedi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS
    Publication number: 20210186961
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity.
    Type: Application
    Filed: June 30, 2020
    Publication date: June 24, 2021
    Inventors: Sandra E. DUNN, Aarthi JAYANTHAN, Jaipal Reddy NAGIREDDY, Subhash ANNEDI, John H. VAN DRIE, Timothy S. DAYNARD, My-my HUYNH
  • Carboxamide derivatives useful as rsk inhibitors
    Patent number: 10758530
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity. Such carboxamide derivatives form bicyclic and tricyclic ring systems and the disease or condition associated with RSK activity in a mammal is cancer.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: September 1, 2020
    Assignee: PHOENIX MOLECULAR DESIGNS
    Inventors: Sandra E. Dunn, Aarthi Jayanthan, Jaipal Reddy Nagireddy, Subhash Annedi, John H. Van Drie, Timothy S. Daynard, My-my Huynh
  • CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS
    Publication number: 20190134029
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity. Such carboxamide derivatives form bicyclic and tricyclic ring systems and the disease or condition associated with RSK activity in a mammal is cancer.
    Type: Application
    Filed: February 17, 2017
    Publication date: May 9, 2019
    Inventors: Sandra E. DUNN, Aarthi JAYANTHAN, Jaipal Reddy NAGIREDDY, Subhash ANNEDI, John H. VAN DRIE, Timothy S. DAYNARD, My-my HUYNH
  • Substituted tetrahydropyrido[3?,2?:4,5]pyrrolo[1,2-?]pyrazine-2-carboxamides as RSK inhibitors
    Patent number: 10081632
    Abstract: Described herein are carboxamide derivatives of Formula (II) that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity: wherein R2, R4a, R4b, R11, R12, and n are defined in the specification.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: September 25, 2018
    Assignee: PHOENIX MOLECULAR DESIGNS
    Inventors: Sandra E. Dunn, Aarthi Jayanthan, Jaipal Reddy Nagireddy, Subhash Annedi, John H. Van Drie, Timothy S. Daynard, My-my Huynh
  • CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS
    Publication number: 20170327501
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity.
    Type: Application
    Filed: July 31, 2017
    Publication date: November 16, 2017
    Inventors: Sandra E. DUNN, Aarthi JAYANTHAN, Jaipal Reddy NAGIREDDY, Subhash ANNEDI, John H. VAN DRIE, Timothy S. DAYNARD, My-my HUYNH
  • Substituted tetrahydropyrido[3?,2?:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors
    Patent number: 9771366
    Abstract: Described herein are carboxamide derivatives of Formula (II) that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity: wherein R2, R4a, R4b, R11, R12, and n are defined in the specification.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: September 26, 2017
    Assignee: PHOENIX MOLECULAR DESIGN
    Inventors: Sandra E. Dunn, Aarthi Jayanthan, Jaipal Reddy Nagireddy, Subhash Annedi, John H. Van Drie, Timothy S. Daynard, My-my Huynh
  • TETRAHYDROPYRIDO[3',2':4,5]PYRROLO[1,2-a]PYRAZINE-2-CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS
    Publication number: 20170240549
    Abstract: Described herein are carboxamide derivatives that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity.
    Type: Application
    Filed: February 17, 2017
    Publication date: August 24, 2017
    Inventors: Sandra E. DUNN, Aarthi JAYANTHAN, Jaipal Reddy NAGIREDDY, Subhash ANNEDI, John H. VAN DRIE, Timothy S. DAYNARD, My-my HUYNH
  • 1,5 And 3,6- substituted indole compounds having NOS inhibitory activity
    Publication number: 20070254940
    Abstract: The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing conditions such as, for example, stroke, reperfusion injury, neurodegeneration, head trauma, CABG, migraine headache with and without aura, migraine with allodynia, central post-stroke pain (CPSP), neuropathic pain, or chronic pain.
    Type: Application
    Filed: April 13, 2007
    Publication date: November 1, 2007
    Inventors: Shawn Maddaford, Jailall Ramnauth, Suman Rakhit, Joanne Patman, Paul Renton, Subhash Annedi
  • Substituted indole compounds having NOS inhibitory activity
    Publication number: 20060258721
    Abstract: The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing conditions such as, for example, stroke, reperfusion injury, neurodegeneration, head trauma, CABG, migraine headache with and without aura, migraine with allodynia, central post-stroke pain (CPSP), neuropathic pain, morphine/opioid induced tolerance and hyperalgesia.
    Type: Application
    Filed: April 13, 2006
    Publication date: November 16, 2006
    Inventors: Shawn Maddaford, Jailall Ramnauth, Suman Rakhit, Joanne Patman, Paul Renton, Subhash Annedi