Patents by Inventor Subrahamanyam Chivukula Sekar

Subrahamanyam Chivukula Sekar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8835145
    Abstract: The invention relates to a thrombolytic enzyme referred to as Thrombinase having a molecular weight of 31,000 to 32,000. Such a thrombolytic enzyme can be used for dissolving blood clots. The process comprises culturing a filtrate of Bacillus sphaericus sero type H5a 5b, removing the cell, subjecting the cell supernatant to filtration, salting out the retentate, subjecting the precipitate to dialysis, reprecipitating the precipitate and then reconstituting in buffer and finally decolorizing, purifying and dialyzing.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: September 16, 2014
    Assignees: National Research Development Corporation, India and Malladi Drugs Pharmaceuticals Ltd.
    Inventors: Subrahamanyam Chivukula Sekar, Sundaramurthy Suresh Babu, Sita Mahadevan
  • Publication number: 20090285793
    Abstract: The invention relates to a thrombolytic enzyme referred to as Thrombinase having a molecular weight of 31,000 to 32,000. Such a thrombolytic enzyme can be used for dissolving blood clots. The process comprises culturing a filtrate of Bacillus sphaericus sero type H5a 5b, removing the cell, subjecting the cell supernatant to filtration, salting out the retentate, subjecting the precipitate to dialysis, reprecipitating the precipitate and then reconstituting in buffer and finally decolourizing, purifying and dialyzing.
    Type: Application
    Filed: October 12, 2007
    Publication date: November 19, 2009
    Applicants: National Research Development Corporation, Malladi Drugs & Pharmaceuticals Ltd.
    Inventors: Perurmadom Ramaiyer Mahadevan, Sita Mahadevan, Subrahamanyam Chivukula Sekar, Sundaramurthy Suresh Babu