Patents by Inventor Sudhakar Kasina

Sudhakar Kasina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9090633
    Abstract: The invention discloses 4-(arylamino)selenophenopyrimidine derivatives of formula (I), hydrates, solvates, isomers, or pharmaceutically acceptable salts thereof; process for their preparation and methods of treating or inhibiting or controlling a cell proliferative disorders, particularly cancer using said compounds. Pharmaceutical compositions comprising 4-(arylamino)selenophenopyrimidine derivatives of formula (I) are useful for the treatment, inhibition, or control of cancer.
    Type: Grant
    Filed: June 7, 2013
    Date of Patent: July 28, 2015
    Assignee: Kasina Laila Innova Pharmaceuticals Private Limited
    Inventors: Sudhakar Kasina, Ganga Raju Gokaraju, Venkateswarlu Somepalli, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Kiran Bhuphatiraju, Trimurtulu Golakoti, Krishanu Sengupta, Venkata Krishna Raju Alluri
  • Patent number: 8954780
    Abstract: A computer-implemented method for transferring input/output operations within computer clusters may include (1) identifying a computer cluster that includes (i) a plurality of nodes configured to facilitate access to a plurality of physical storage devices and (ii) at least one computing object that represents data stored on the physical storage devices, (2) detecting at least one failure that prevents at least one node within the computer cluster from performing at least one input/output operation on the computing object that represents the data stored on the physical storage devices, (3) identifying at least one other node within the computer cluster that is able to perform the input/output operation on the computing object, and then (4) directing the other node within the computer cluster to perform the input/output operation on the computing object. Various other methods, systems, and computer-readable media are also disclosed.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: February 10, 2015
    Assignee: Symantec Corporation
    Inventors: Chaitanya Yalamanchili, Prasanta Dash, Asmita Jagtap, Sudhakar Kasina
  • Patent number: 8906344
    Abstract: The invention relates to 18F-labeled compounds of formula (I), hydrates, isomers, or pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions. The invention relates to the methods of diagnosing kidney function in humans by PET imaging.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: December 9, 2014
    Assignee: Kasina Laila Innova Pharmaceuticals Private Limited
    Inventors: Sudhakar Kasina, Venkateswarlu Somepalli, Paul G. Abrams, Rama Raju Gokaraju
  • Patent number: 8815879
    Abstract: Selenophene compounds of formula (I) are described herein. In the compounds of Formula (I), ring A is a 6-membered aromatic fused ring, optionally containing one, two or three nitrogen atoms; a 5-membered heteroaromatic fused ring; or a mono- or bicyclic saturated heterocyclic fused ring having at least one ring member selected from the group consisting of N, O, S, SO and SO2; Y in ring B is nitrogen or substituted carbon; X is NR6, O, S, S(O), or S(O)2. R1, R2, R3, R4, and R6 are defined in the specification. Selenophene compounds of formula (I) may be used in methods of treating cell proliferative disorders, particularly cancer. Pharmaceutical compositions containing selenophene compounds of formula (I) may be used for treatment, inhibition, or control of cancer.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: August 26, 2014
    Assignee: Kasina Laila Innova Pharmaceuticals Private Limited
    Inventors: Sudhakar Kasina, Ganga Raju Gokaraju, Venkateswarlu Somepalli, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Kiran Bhupathiraju, Trimurtulu Golakoti, Krishanu Sengupta, Venkata Krishna Raju Alluri
  • Publication number: 20140086837
    Abstract: The invention relates to 18F-labeled compounds of formula (I), hydrates, isomers, or pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions. The invention relates to the methods of diagnosing kidney function in humans by PET imaging.
    Type: Application
    Filed: September 19, 2013
    Publication date: March 27, 2014
    Applicant: KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITED
    Inventors: Sudhakar KASINA, Venkateswarlu Somepalli, Paul G. Abrams, Rama Raju Gokaraju
  • Publication number: 20130287767
    Abstract: The invention discloses 4-(arylamino)selenophenopyrimidine derivatives of formula (I), hydrates, solvates, isomers, or pharmaceutically acceptable salts thereof; process for their preparation and methods of treating or inhibiting or controlling a cell proliferative disorders, particularly cancer using said compounds. Pharmaceutical compositions comprising 4-(arylamino)selenophenopyrimidine derivatives of formula (I) are useful for the treatment, inhibition, or control of cancer.
    Type: Application
    Filed: June 7, 2013
    Publication date: October 31, 2013
    Inventors: Ganga Raju GOKARAJU, Sudhakar KASINA, Venkateswarlu SOMEPALLI, Rama Raju GOKARAJU, Venkata Kanaka Ranga Raju GOKARAJU, Kiran BHUPHATIRAJU, Trimurtulu GOLAKOTI, Krishanu SENGUPTA, Venkata Krishna Raju ALLURI
  • Publication number: 20130266563
    Abstract: Selenophene compounds of formula (I) are described herein. In the compounds of Formula (I), ring A is a 6-membered aromatic fused ring, optionally containing one, two or three nitrogen atoms; a 5-membered heteroaromatic fused ring; or a mono- or bicyclic saturated heterocyclic fused ring having at least one ring member selected from the group consisting of N, O, S, SO and SO2; Y in ring B is nitrogen or substituted carbon; X is NR6, O, S, S(O), or S(O)2. R1, R2, R3, R4, and R6 are defined in the specification. Selenophene compounds of formula (I) may be used in methods of treating cell proliferative disorders, particularly cancer. Pharmaceutical compositions containing selenophene compounds of formula (I) may be used for treatment, inhibition, or control of cancer.
    Type: Application
    Filed: May 17, 2013
    Publication date: October 10, 2013
    Inventors: Ganga Raju Gokaraju, Sudhakar Kasina, Venkateswarlu Somepalli, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Kiran Bhupathiraju, Trimurtulu Golakoti, Krishanu Sengupta, Venkata Krishna Raju Alluri
  • Patent number: 8258119
    Abstract: The present invention discloses triazene analogs of the general formula (I) and formula (II), their tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts thereof for the metastatic malignant melanoma and other cancers including but not limited to lymphomas, sarcomas, carcinomas, and gliomas. The invention further discloses a process for the preparation of the above said triazene analogs of formula (I) and formula (II), and their pharmaceutically acceptable compositions.
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: September 4, 2012
    Assignee: Kasina Laila Innova Pharmaceuticals
    Inventors: Ganga Raju Gokaraju, Sudhakar Kasina, Rama Raju Gokaraju, Trimurtulu Golakoti, Venkateswarlu Somepalli, Sengupta Krishanu, Kiran Bhupathiraju
  • Patent number: 8143237
    Abstract: Selenopheno triazene analogs, their compositions, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts and mixtures thereof are useful for the treatment of metastatic malignant melanoma and other cancers. The selenopheno triazene analogs have the general formulae (I) or (II): wherein the substituents R1, R2, R3, R6, and R7 are as described in the specification. Other cancers include which may be treated with these compounds include, but are not limited to, malignant melanoma, leukemia, lymphomas (Hodgkins and non-Hodgkins), sarcomas (Ewing's sarcoma), brain tumors, central nervous system (CNS) metastases, gliomas, carcinomas such as breast cancer, prostate cancer, lung cancer (small cell and non-small cell), colon cancer, pancreatic cancer, Head and Neck cancers and oropharyngeal squamous cell carcinoma.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: March 27, 2012
    Assignee: Kasina Laila Innova Pharmaceuticals Private Limited
    Inventors: Ganga Raju Gokaraju, Sudhakar Kasina, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Venkateswarlu Somepalli, Trimurtulu Golakoti, Kiran Bhupathiraju, Sengupta Krishanu, Venkata Krishna Raju Alluri
  • Publication number: 20110269943
    Abstract: Radiolabeled annexin and modified annexin conjugates useful for imaging vascular thrombi are described. Methods for making and using such radiolabeled annexin conjugates are also provided.
    Type: Application
    Filed: June 28, 2010
    Publication date: November 3, 2011
    Applicants: University of Washington, Poniard Pharmaceuticals, Inc.
    Inventors: Sudhakar Kasina, John M. Reno, Alan R. Fritzberg, Jonathan Tait
  • Publication number: 20100272678
    Abstract: Selenopheno triazene analogs, their compositions, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts and mixtures thereof are useful for the treatment of metastatic malignant melanoma and other cancers. The selenopheno triazene analogs have the general formulae (I) or (II): wherein the substituents R1, R2, R3, R6, and R7 are as described in the specification. Other cancers include which may be treated with these compounds include, but are not limited to, malignant melanoma, leukemia, lymphomas (Hodgkins and non-Hodgkins), sarcomas (Ewing's sarcoma), brain tumors, central nervous system (CNS) metastases, gliomas, carcinomas such as breast cancer, prostate cancer, lung cancer (small cell and non-small cell), colon cancer, pancreatic cancer, Head and Neck cancers and oropharyngeal squamous cell carcinoma.
    Type: Application
    Filed: April 26, 2010
    Publication date: October 28, 2010
    Applicant: KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITE
    Inventors: Ganga Raju GOKARAJU, Sudhakar Kasina, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Venkateswarlu Somepalli, Trimurtulu Golakoti, Kiran Bhupathiraju, Sengupta Krishanu, Venkata Krishna Raju Alluri
  • Patent number: 7744853
    Abstract: Radiolabeled annexin and modified annexin conjugates useful for imaging vascular thrombi are described. Methods for making and using such radiolabeled annexin conjugates are also provided.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: June 29, 2010
    Assignee: Poniard Pharmaceuticals, Inc.
    Inventors: Sudhakar Kasina, John M. Reno, Alan R. Fritzberg, Jonathan Tait
  • Publication number: 20100068178
    Abstract: The present invention discloses triazene analogs of the general formula (I) and formula (II), their tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts thereof for the metastatic malignant melanoma and other cancers including but not limited to lymphomas, sarcomas, carcinomas, and gliomas. The invention further discloses a process for the preparation of the above said triazene analogs of formula (I) and formula (II), and their pharmaceutically acceptable compositions.
    Type: Application
    Filed: September 15, 2009
    Publication date: March 18, 2010
    Applicant: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Sudhakar Kasina, Rama Raju Gokaraju, Trimurtulu Golakoti, Venkateswarlu Somepalli, Sengupta Krishanu, Kiran Bhupathiraju
  • Patent number: 7674886
    Abstract: The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hydrogen, and methods for making and using these compounds.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: March 9, 2010
    Assignee: Poniard Pharmaceuticals, Inc.
    Inventor: Sudhakar Kasina
  • Patent number: 7608242
    Abstract: A peptide-chelate conjugate with affinity for the ST receptor is disclosed, wherein the chelate is tetradentate. The peptide-chelate conjugate of the invention may be labelled with a radiometal to provide a metal complex. A radiopharmaceutical composition comprising the metal complex is provided. which is suitable for the diagnostic imaging of colorectal cancer. Also provided for in the invention is a kit for the preparation of the radiopharmaceutical preparation.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: October 27, 2009
    Assignee: GE Healthcare Limited
    Inventors: Alan Cuthbertson, Marivi Mendizabal, Mark Dixon, Anthony E. Storey, Edward R. Bacon, Vinay Chandrakant Desai, Sudhakar Kasina, Henry Raphael Wolfe
  • Patent number: 7511070
    Abstract: The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.
    Type: Grant
    Filed: November 9, 2005
    Date of Patent: March 31, 2009
    Assignee: Poniard Pharmaceuticals, Inc.
    Inventors: David J. Grainger, James C. Metcalfe, Sudhakar Kasina
  • Publication number: 20080227961
    Abstract: The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hydrogen, and methods for making and using these compounds.
    Type: Application
    Filed: September 4, 2007
    Publication date: September 18, 2008
    Inventor: Sudhakar Kasina
  • Patent number: 7268220
    Abstract: The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hydrogen, and methods for making and using these compounds.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: September 11, 2007
    Assignee: Poniard Pharmaceuticals, Inc.
    Inventor: Sudhakar Kasina
  • Patent number: 7115248
    Abstract: Radiolabeled annexin and modified annexin conjugates useful for imaging vascular thrombi are described. Methods for making and using such radiolabeled annexin conjugates are also provided.
    Type: Grant
    Filed: April 8, 2004
    Date of Patent: October 3, 2006
    Assignee: NeoRx Corporation
    Inventors: Sudhakar Kasina, John M Reno, Louis J Theodore
  • Patent number: 7084171
    Abstract: The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.
    Type: Grant
    Filed: April 19, 2004
    Date of Patent: August 1, 2006
    Assignee: NeoRx Corporation
    Inventors: David J. Grainger, James C. Metcalfe, Sudhakar Kasina