Patents by Inventor Sun-Ki Chang

Sun-Ki Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210317142
    Abstract: The present invention provides a novel method for preparing high-purity gadobutrol or hydrates thereof. The preparation method of the present invention can have an advantage of simplifying a process by forming a gadolinium complex in-situ without purification of a butrol intermediate and omitting a resin purification process unlike a conventional method for synthesizing gadobutrol. In addition, the preparation method of the present invention can be used to produce high-purity gadobutrol or hydrates thereof at a high yield only through the simple process as above, and thus can be useful in mass production.
    Type: Application
    Filed: August 23, 2019
    Publication date: October 14, 2021
    Inventors: Changho BYEON, Hoejin YOON, Moonsu KIM, Seongsu JEONG, Jongmoon PARK, Junwon LEE, Seokhun WOO, Sun Ki CHANG
  • Patent number: 10702859
    Abstract: The present disclosure provides a method for preparing ((2,2-dimethyl-1,3-dioxane-5,5-diyl)bis(methylene))bis(bis(2-methoxyphenyl)phosphine), a ligand for a polyketone polymerization catalyst, under mild conditions with high purity and high yield. Therefore, the preparation method of the present disclosure can be easily applied to mass production.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: July 7, 2020
    Assignee: ST PHARM CO., LTD.
    Inventors: Geun Jho Lim, Sun Ki Chang, Hyun Woo Baek, Jun Hyun Oh, Yeong Hun Kim
  • Patent number: 10538504
    Abstract: Disclosed is a method of preparing an intermediate for an oxazolidinone derivative, which enables 5-bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine to be produced at high yield and high purity, thus exhibiting high preparation efficiency under optimal processing conditions and making it suitable for industrial mass production.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: January 21, 2020
    Assignee: ST PHARM CO., LTD.
    Inventors: Seok Hun Woo, YunHee Choi, Hong Jun Kim, Sun Ki Chang, Geun Jho Lim
  • Patent number: 10501403
    Abstract: The present invention relates to a novel method for preparing (S)—N1-(2-aminoethyl)-3-(4-alkoxyphenyl)propane-1,2-diamine trihydrochloride.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: December 10, 2019
    Assignee: ST PHARM CO., LTD.
    Inventors: Yeong Hun Kim, Hyun Woo Baek, Hyeon Jin Lee, Sang Kyu Kang, Sun Ki Chang, Geun Jho Lim
  • Patent number: 10428096
    Abstract: Provided are a novel polyketone polymerization catalyst and a method of preparing a ligand, which can reduce production costs and can enable commercial mass synthesis by using ((2,2-dimethyl-1,3-dioxane-5,5-diyl)bis(methylene))bis(bis(2-methoxyphenyl)phosphine) as a ligand constituting the polykeytone polymerization catalyst, the ligand having a simple structure and a small molecular weight while having high activity.
    Type: Grant
    Filed: July 16, 2014
    Date of Patent: October 1, 2019
    Assignees: HYOSUNG CHEMICAL CORPORATION, ST PHARM CO., LTD.
    Inventors: Jae Yoon Shim, Sun Kue Kim, Hae Souk Cho, Ji Hwan Choi, Geun Jho Lim, Sun Ki Chang, Min Kyu Kim, In Hyeok Baek
  • Publication number: 20190284126
    Abstract: The present invention relates to a novel method for preparing (S)—N1-(2-aminoethyl)-3-(4-alkoxyphenyl)propane-1,2-diamine trihydrochloride.
    Type: Application
    Filed: November 3, 2017
    Publication date: September 19, 2019
    Inventors: Yeong Hun KIM, Hyun Woo BAEK, Hyeon Jin LEE, Sang Kyu KANG, Sun Ki CHANG, Geun Jho LIM
  • Publication number: 20180361369
    Abstract: The present disclosure provides a method for preparing ((2,2-dimethyl-1,3-dioxane-5,5-diyl)bis(methylene))bis(bis(2-methoxyphenyl)phosphine), a ligand for a polyketone polymerization catalyst, under mild conditions with high purity and high yield. Therefore, the preparation method of the present disclosure can be easily applied to mass production.
    Type: Application
    Filed: November 11, 2016
    Publication date: December 20, 2018
    Inventors: Geun Jho Lim, Sun Ki Chang, Hyun Woo Baek, Jun Hyun Oh, Yeong Hun Kim
  • Publication number: 20180346443
    Abstract: Disclosed is a method of preparing an intermediate for an oxazolidinone derivative, which enables 5-bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine to be produced at high yield and high purity, thus exhibiting high preparation efficiency under optimal processing conditions and making it suitable for industrial mass production.
    Type: Application
    Filed: December 9, 2016
    Publication date: December 6, 2018
    Inventors: Seok Hun Woo, YunHee Choi, Hong Jun Kim, Sun Ki Chang, Geun Jho Lim
  • Patent number: 10065933
    Abstract: The present disclosure relates to a novel method for preparing high-purity gadobutrol. The present disclosure can be easily applied to a large scale production because purity of intermediate can be managed via simple and mild process and accordingly, high-purity or ultra high-purity gadobutrol that has higher purity than previous gadobutrol can be prepared in high yield therethrough.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: September 4, 2018
    Assignee: ST PHARM CO., LTD.
    Inventors: Geun Jho Lim, Sun Ki Chang, Chang Ho Byeon, Hoe Jin Yoon, Moon Soo Kim
  • Publication number: 20170342038
    Abstract: The present disclosure relates to a novel method for preparing high-purity gadobutrol. The present disclosure can be easily applied to a large scale production because purity of intermediate can be managed via simple and mild process and accordingly, high-purity or ultra high-purity gadobutrol that has higher purity than previous gadobutrol can be prepared in high yield therethrough.
    Type: Application
    Filed: December 28, 2015
    Publication date: November 30, 2017
    Applicant: ST PHARM CO., LTD.
    Inventors: Geun Jho LIM, Sun Ki CHANG, Chang Ho BYEON, Hoe Jin YOON, Moon Soo Kim
  • Patent number: 9822084
    Abstract: Disclosed is a novel method of preparing highly pure calcobutrol using an intermediate (butrol) of gadobutrol without using highly pure gadobutrol. This method is capable of obtaining calcobutrol at high purity and high yield through a simple and environmentally friendly process, and thus can be easily applied to mass production.
    Type: Grant
    Filed: September 7, 2015
    Date of Patent: November 21, 2017
    Assignee: ST PHARM CO., LTD.
    Inventors: Geun Jho Lim, Sun Ki Chang, Chang Ho Byeon, Hoe Jin Yoon, Moon Soo Kim
  • Patent number: 9790170
    Abstract: The present invention provides a novel method for preparing lacosamide with high chiral purity from D-serine. The method of the present invention can obtain lacosamide with high chiral purity in a high yield through a simple and environmentally-friendly process and thus can be easily applied to mass production.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: October 17, 2017
    Assignee: ST PHARM CO., LTD.
    Inventors: Geun Jho Lim, Sun Ki Chang, Jae Hun Kim, Jong Moon Park
  • Publication number: 20170260148
    Abstract: Disclosed is a novel method of preparing highly pure calcobutrol using an intermediate (butrol) of gadobutrol without using highly pure gadobutrol. This method is capable of obtaining calcobutrol at high purity and high yield through a simple and environmentally friendly process, and thus can be easily applied to mass production.
    Type: Application
    Filed: September 7, 2015
    Publication date: September 14, 2017
    Inventors: Geun Jho LIM, Sun Ki CHANG, Chang Ho BYEON, Hoe Jin YOON, Moon Soo KIM
  • Publication number: 20160333036
    Abstract: Provided are a novel polyketone polymerization catalyst and a method of preparing a ligand, which can reduce production costs and can enable commercial mass synthesis by using ((2,2-dimethyl-1,3-dioxane-5,5-diyl)bis(methylene))bis(bis(2-methoxyphenyl)phosphine) as a ligand constituting the polykeytone polymerization catalyst, the ligand having a simple structure and a small molecular weight while having high activity.
    Type: Application
    Filed: July 16, 2014
    Publication date: November 17, 2016
    Inventors: Jae Yoon SHIM, Sun Kue KIM, Hae Souk CHO, Ji Hwan CHOI, Geun Jho LIM, Sun Ki CHANG, Min Kyu KIM, In Hyeok BAEK
  • Publication number: 20160332958
    Abstract: The present invention provides a novel method for preparing lacosamide with high chiral purity from D-serine. The method of the present invention can obtain lacosamide with high chiral purity in a high yield through a simple and environmentally-friendly process and thus can be easily applied to mass production.
    Type: Application
    Filed: October 27, 2014
    Publication date: November 17, 2016
    Inventors: Geun Jho LIM, Sun Ki CHANG, Jae Hun KIM, Jong Moon PARK
  • Patent number: 9249109
    Abstract: The present invention relates to an improved method for preparing dipeptidyl peptidase-IV inhibitor intermediates. The present invention is able to reduce preparation costs by using low cost reagents on reaction and is able to be used in mass production by improving yield.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: February 2, 2016
    Assignee: DONG-A PHARMACEUTICAL CO., LTD.
    Inventors: Woo Young Kwak, Heung Jae Kim, Jong Pil Min, Tae Hyun Yoon, Moohi Yoo, Geun Gho Lim, Sun Ki Chang
  • Patent number: 9006436
    Abstract: The present invention provides a method which enables the simple, economical and high-yield production which is a key intermediate of antidiabetic drug Januvia.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: April 14, 2015
    Assignee: ST Pharm Co., Ltd.
    Inventors: Geun Gho Lim, Sun Ki Chang, Chang Ho Byeon
  • Publication number: 20150025241
    Abstract: The present invention relates to an improved method for preparing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention is able to reduce preparation costs by using low cost reagents on reaction and is able to be used in mass production by improving yield.
    Type: Application
    Filed: October 3, 2014
    Publication date: January 22, 2015
    Inventors: Woo Young KWAK, Heung Jae KIM, Jong Pil MIN, Tae Hyun YOON, Moohi YOO, Geun Gho LIM, Sun Ki CHANG
  • Publication number: 20140005394
    Abstract: The present invention provides a method which enables the simple, economical and high-yield production which is a key intermediate of antidiabetic drug Januvia.
    Type: Application
    Filed: January 18, 2012
    Publication date: January 2, 2014
    Applicant: ST PHARM CO., LTD
    Inventors: Geun Gho Lim, Sun Ki Chang, Chang Ho Byeon
  • Publication number: 20120016125
    Abstract: The present invention relates to an improved method for preparing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention is able to reduce preparation costs by using low cost reagents on reaction and is able to be used in mass production by improving yield.
    Type: Application
    Filed: March 30, 2010
    Publication date: January 19, 2012
    Applicant: DONG-A PHARMACEUTICAL. CO., LTD
    Inventors: Woo Young Kwak, Heung Jae Kim, Jong Pil Min, Tae Hyun Yoon, Moohi Yoo, Geun Gho Lim, Sun Ki Chang