Patents by Inventor Surya Reis

Surya Reis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Photoswitchable HDAC inhibitors
    Patent number: 11596691
    Abstract: This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: March 7, 2023
    Assignee: The General Hospital Corporation
    Inventors: Ralph Mazitschek, Balaram Ghosh, James Adam Hendricks, Surya Reis, Stephen John Haggarty
  • Photoswitchable HDAC Inhibitors
    Publication number: 20210162048
    Abstract: This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same.
    Type: Application
    Filed: November 6, 2020
    Publication date: June 3, 2021
    Inventors: Ralph Mazitschek, Balaram Ghosh, James Adam Hendricks, Surya Reis, Stephen John Haggarty
  • Photoswitchable HDAC inhibitors
    Patent number: 10828367
    Abstract: This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: November 10, 2020
    Assignee: The General Hospital Corporation
    Inventors: Ralph Mazitschek, Balaram Ghosh, James Adam Hendricks, Surya Reis, Stephen John Haggarty
  • Photoswitchable HDAC Inhibitors
    Publication number: 20190070295
    Abstract: This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same.
    Type: Application
    Filed: May 1, 2018
    Publication date: March 7, 2019
    Inventors: Ralph Mazitschek, Balaram Ghosh, James Adam Hendricks, Surya Reis, Stephen John Haggarty
  • Photoswitchable HDAC inhibitors
    Patent number: 9981038
    Abstract: This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same. Provided herein are inhibitors of HDAC having photoswitchable modulators of protein function with short thermal relaxation kinetics. The compounds are diazo compounds including a substituted or unsubstituted aryl or heteroaryl ring, wherein at least one of the rings is substituted with one or more HDAC targeting elements.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: May 29, 2018
    Assignee: The General Hospital Corporation
    Inventors: Ralph Mazitschek, Balaram Ghosh, James Adam Hendricks, Surya Reis, Stephen John Haggarty
  • Photoswitchable HDAC Inhibitors
    Publication number: 20160022817
    Abstract: This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same. Provided herein are inhibitors of HDAC having photoswitchable modulators of protein function with short thermal relaxation kinetics. The compounds are diazo compounds including a substituted or unsubstituted aryl or heteroaryl ring, wherein at least one of the rings is substituted with one or more HDAC targeting elements.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 28, 2016
    Applicant: The General Hospital Corporation
    Inventors: Ralph Mazitschek, Balaram Ghosh, James Adam Hendricks, Surya Reis, Stephen John Haggarty