Patents by Inventor Susan Gould-Fogerite

Susan Gould-Fogerite has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050008686
    Abstract: The present invention provides novel fragile nutrient cochleates that generally include one or more encochleated fragile nutrients, e.g., beta carotene, and methods for making the same. Also provided are methods for the use and administration of the fragile nutrient cochleates of the invention.
    Type: Application
    Filed: January 15, 2004
    Publication date: January 13, 2005
    Inventors: Raphael Mannino, Sara Krause-Elsmore, Susan Gould-Fogerite, David Delmarre, Feng Tan
  • Publication number: 20040146551
    Abstract: The present invention provides geodate delivery vehicles and methods of manufacture and administration. A vehicle including a lipid monolayer disposed about a hydrophobic domain is disclosed, that can be part of an emulsion or other mixture, or further disposed in a lipid strata. A vehicle including a lipid strata disposed about a hydrophobic domain is also disclosed. The vehicle can be incorporated into a variety of medicinal, food preparations, and personal care products to deliver or stabilize a cargo moiety. Packaged delivery vehicles for later addition of cargo moieties are also contemplated.
    Type: Application
    Filed: November 3, 2003
    Publication date: July 29, 2004
    Applicant: BioDelivery Sciences International, Inc.
    Inventors: Raphael J. Mannino, Sara L. Krause-Elsmore, Susan Gould-Fogerite, David Delmarre, Ruying Lu
  • Publication number: 20020034822
    Abstract: An integrative DNA vector and one or more viral proteins having affinity for DNA are packaged in cochleate precipitates. The integrative DNA vector contains one or more therapeutic nucleotide sequences that are preferably positioned between DNA substrates for the proteins. Upon contact with a lipid bilayer of a target cell, the cochleate vector structure delivers one or more of the therapeutic nucleotide sequences and one or more proteins to the interior of the target cell. Upon entry into the cell, the proteins facilitate the integration of the therapeutic nucleotide sequence into the genome of the host cell.
    Type: Application
    Filed: September 21, 2001
    Publication date: March 21, 2002
    Applicant: UNIVERSITY OF MARYLAND
    Inventors: David Margolis, Susan Gould-Fogerite, Raphael James Mannino
  • Patent number: 6340591
    Abstract: An integrative DNA vector and one or more viral proteins having affinity for DNA are packaged in cochleate precipitates. The integrative DNA vector contains one or more therapeutic nucleotide sequences that are preferably positioned between DNA substrates for the proteins. Upon contact with a lipid bilayer of a target cell, the cochleate vector structure delivers one or more of the therapeutic nucleotide sequences and one or more proteins to the interior of the target cell. Upon entry into the cell, the proteins facilitate the integration of the therapeutic nucleotide sequence into the genome of the host cell.
    Type: Grant
    Filed: December 14, 1998
    Date of Patent: January 22, 2002
    Assignees: University of Maryland, University of Medicine and Dentistry of New Jersey
    Inventors: David Margolis, Susan Gould-Fogerite, Raphael James Mannino
  • Patent number: 6165502
    Abstract: A protein-lipid vesicle that can be used to make an autogenous vaccine comprises patient-specific antigen, adjuvant or immunomodulator, and lipid carrier. In addition, a negatively charged lipid component is desirably included. The autogenous vaccine is useful to treat individuals with chronic diseases, including chronic infectious diseases and neoplasias. The chronic infectious diseases that can be treated include disease caused by infection with human immunodeficiency viruses.
    Type: Grant
    Filed: November 9, 1998
    Date of Patent: December 26, 2000
    Assignees: Albany Medical College, Medical College of New Jersey
    Inventors: James M. Oleske, Thomas N. Denny, Anthony J. Scolpino, Eleonora Feketeova, Susan Gould-Fogerite, Raphael J. Mannino
  • Patent number: 5994318
    Abstract: The instant disclosure relates to cochleates comprising a) a biologically relevant molecule component b) a negatively charged lipid component, and c) a divalent cation component. The cochleate has an extended shelf life, even in a desiccated state. Advantageously, the cochleate can be ingested. The biologically relevant molecule can be a topical application and an in vitro treatment, a polypeptide a drug, a nutrient, or a flavor.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: November 30, 1999
    Assignees: Albany Medical College, University of Medicine and Dentistry of New Jersey
    Inventors: Susan Gould-Fogerite, Raphael James Mannino
  • Patent number: 5840707
    Abstract: The instant disclosure relates to cochleates comprising a) a biologically relevant molecule component b) a negatively charged lipid component, and c) a divalent cation component. The cochleate has an extended shelf life, even in a desiccated state. Advantageously, the cochleate can be ingested. The biologically relevant molecule can be a polynucleotide.
    Type: Grant
    Filed: February 22, 1995
    Date of Patent: November 24, 1998
    Assignees: Albany Medical College, University of Medicine and Dentistry of New Jersey
    Inventors: Raphael James Mannino, Susan Gould-Fogerite
  • Patent number: 5834015
    Abstract: A protein-lipid vesicle that can be used to make an autogenous vaccine comprises patient-specific antigen, adjuvant or immunomodulator, and lipid carrier. In addition, a negatively charged lipid component is desirably included. The autogenous vaccine is useful to treat individuals with chronic diseases, including chronic infectious diseases and neoplasias. The chronic infectious diseases that can be treated include disease caused by infection with human immunodeficiency viruses.
    Type: Grant
    Filed: September 11, 1996
    Date of Patent: November 10, 1998
    Assignees: Albany Medical College, University of Medicine and Dentistry of New Jersey
    Inventors: James M. Oleske, Thomas N. Denny, Anthony J. Scolpino, Eleonora Feketeova, Susan Gould-Fogerite, Raphael J. Mannino
  • Patent number: 5643574
    Abstract: A method is described of immunizing a host by administering a biologically effective amount of a protein- or peptide-cochleate comprising at least a protein or peptide to which an immune response is elicited, a negatively charged lipid, and a divalent cation.
    Type: Grant
    Filed: October 4, 1993
    Date of Patent: July 1, 1997
    Assignees: Albany Medical College, University of Medicine & Dentistry of New Jersey
    Inventors: Susan Gould-Fogerite, Raphael James Mannino