Patents by Inventor Susan R. Rippin

Susan R. Rippin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMAC mimetic
    Patent number: 11951147
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Grant
    Filed: May 3, 2022
    Date of Patent: April 9, 2024
    Assignee: MEDIVIR AB
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • SMAC MIMETIC
    Publication number: 20230149500
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Application
    Filed: May 3, 2022
    Publication date: May 18, 2023
    Inventors: Stephen M. CONDON, Yijun DENG, Matthew G. LAPORTE, Susan R. RIPPIN
  • SMAC mimetic
    Patent number: 11351221
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: June 7, 2022
    Assignee: MEDIVIR AB
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • SMAC Mimetic
    Publication number: 20200282002
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Application
    Filed: February 6, 2020
    Publication date: September 10, 2020
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • SMAC mimetic
    Patent number: 10596220
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: March 24, 2020
    Assignee: Medivir AB
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • SMAC Mimetic
    Publication number: 20190255139
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Application
    Filed: April 29, 2019
    Publication date: August 22, 2019
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • SMAC mimetic
    Patent number: 10314881
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: June 11, 2019
    Assignee: Medivir AB
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • SMAC Mimetic
    Publication number: 20180303897
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Application
    Filed: June 27, 2018
    Publication date: October 25, 2018
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • SMAC Mimetic
    Patent number: 10034912
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: July 31, 2018
    Assignee: TetraLogic Birinapant UK Ltd.
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • Dimeric IAP inhibitors
    Patent number: 9920093
    Abstract: Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes. In various embodiments of the invention the Smac mimetics of the invention are combined with chemotherapeutic agents, including, but not limited to topoisomerase inhibitors, kinase inhibitors, NSAIDs, taxanes and platinum containing compounds use broader language.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: March 20, 2018
    Assignee: TetraLogic Birinapant UK Ltd.
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan R. Rippin
  • IAP binding compounds
    Patent number: 9840464
    Abstract: IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a Kd of less than 0.1 micromolar. Methods of using these IAP binding molecules for therapeutic, diagnostic, and assay purposed are also disclosed.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: December 12, 2017
    Assignee: TetraLogic Birinapant UK Ltd.
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan R. Rippin
  • SMAC Mimetic
    Publication number: 20170182116
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Application
    Filed: November 7, 2016
    Publication date: June 29, 2017
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • Dimeric IAP Inhibitors
    Publication number: 20160355547
    Abstract: Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes.
    Type: Application
    Filed: August 17, 2016
    Publication date: December 8, 2016
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan R. Rippin
  • IAP Binding Compounds
    Publication number: 20160289183
    Abstract: IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a Kd of less than 0.1 micromolar. Methods of using these IAP binding molecules for therapeutic, diagnostic, and assay purposed are also disclosed.
    Type: Application
    Filed: June 15, 2016
    Publication date: October 6, 2016
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan R. Rippin
  • IAP binding compounds
    Patent number: 9394249
    Abstract: IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a Kd of less than 0.1 micromolar. Methods of using these IAP binding molecules for therapeutic, diagnostic, and assay purposed are also disclosed.
    Type: Grant
    Filed: July 16, 2014
    Date of Patent: July 19, 2016
    Assignee: TetraLogic Birinapant UK Ltd.
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan R. Rippin
  • Dimeric IAP Inhibitors
    Publication number: 20160052965
    Abstract: Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes.
    Type: Application
    Filed: October 15, 2015
    Publication date: February 25, 2016
    Applicant: TETRALOGIC BIRINAPANT UK LTD.
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan R. Rippin
  • Dimeric IAP inhibitors
    Patent number: 9187490
    Abstract: Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of IAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes. In various embodiments of the invention the Smac mimetics of the invention are combined with chemotherapeutic agents, including, but not limited to topoisomerase inhibitors, kinase inhibitors, NSAIDs, taxanes and platinum containing compounds use broader language.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: November 17, 2015
    Assignee: TetraLogic Birinapant UK Ltd.
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan R. Rippin
  • IAP Binding Compounds
    Publication number: 20150307448
    Abstract: IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a Kd of less than 0.1 micromolar. Methods of using these IAP binding molecules for therapeutic, diagnostic, and assay purposed are also disclosed.
    Type: Application
    Filed: July 16, 2014
    Publication date: October 29, 2015
    Applicant: TetraLogic Pharmaceuticals Corporation
    Inventors: Stephen M. Condon, Matthew G. Laporte, Yijun Deng, Susan R. Rippin
  • SMAC Mimetic for Treating Myelodysplastic Syndromes
    Publication number: 20150158908
    Abstract: A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
    Type: Application
    Filed: January 28, 2015
    Publication date: June 11, 2015
    Inventors: Stephen M. Condon, Yijun Deng, Matthew G. Laporte, Susan R. Rippin
  • Compounds, compositions and methods for treatment and prevention of infections and associated diseases
    Patent number: 9045418
    Abstract: Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: June 2, 2015
    Assignee: SIGA TECHNOLOGIES, INC.
    Inventors: Robert Jordan, Thomas R. Bailey, Susan R. Rippin, Dongcheng Dai