Patents by Inventor Susumu Hama

Susumu Hama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9526791
    Abstract: A problem to be solved by the present invention is to provide a peptide compound for producing a drug delivery carrier capable of releasing a target substance in a weakly acidic pH environment. The present invention provides a peptide compound comprising a hydrophilic amino acid block and a hydrophobic amino acid block; [1] the peptide compound containing 24 to 36 amino acids in total; [2] the hydrophilic amino acid block containing 4 to 10 amino acids in total and having an average hydropathy index of ?3.0 to ?1.0; and [3] the hydrophobic amino acid block containing 20 to 32 amino acids in total, containing one or more His residues, and having an average hydropathy index of 1.0 to 2.5.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: December 27, 2016
    Assignee: Taiho Pharmaceutical Co., Ltd.
    Inventors: Kentaro Kogure, Susumu Hama
  • Patent number: 9186389
    Abstract: The present invention provides a nanoparticle and cell delivery agent, capable of releasing a target substance in a weakly acidic pH environment. Specifically, the present invention provides a nanoparticle comprising a peptide and a particle-forming component, the particle-forming component forming a liposome or a micelle, the peptide having a sequence with 2 to 8 units starting with His (histidine) and ending with an acidic amino acid, wherein each of the units may be identical or different.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: November 17, 2015
    Assignee: Taiho Pharmaceutical Co., Ltd.
    Inventors: Kentaro Kogure, Susumu Hama
  • Publication number: 20150250893
    Abstract: A problem to be solved by the present invention is to provide a peptide compound for producing a drug delivery carrier capable of releasing a target substance in a weakly acidic pH environment. The present invention provides a peptide compound comprising a hydrophilic amino acid block and a hydrophobic amino acid block; [1] the peptide compound containing 24 to 36 amino acids in total; [2] the hydrophilic amino acid block containing 4 to 10 amino acids in total and having an average hydropathy index of ?3.0 to ?1.0; and [3] the hydrophobic amino acid block containing 20 to 32 amino acids in total, containing one or more His residues, and having an average hydropathy index of 1.0 to 2.5.
    Type: Application
    Filed: October 21, 2013
    Publication date: September 10, 2015
    Applicant: Taiho Pharmaceutical Co., Ltd.
    Inventors: Kentaro Kogure, Susumu Hama
  • Publication number: 20140044778
    Abstract: The present invention provides a nanoparticle and cell induction agent, capable of releasing a target substance in a weakly acidic pH environment. Specifically, the present invention provides a nanoparticle comprising a peptide and a particle-forming component, the particle-forming component forming a liposome or a micelle, the peptide having a sequence with 2 to 8 units starting with His (histidine) and ending with an acidic amino acid, wherein each of the units may be identical or different.
    Type: Application
    Filed: April 24, 2012
    Publication date: February 13, 2014
    Applicant: TAIHO PHARMACEUTICAL CO., LTD.
    Inventors: Kentaro Kogure, Susumu Hama
  • Patent number: 6079887
    Abstract: A printer having an ink jet type printing section for printing on a first cut sheet of paper having a first shape or a second cut sheet of paper having a second shape. A set of transfer rollers is provided adjacent to an insertion aperture for the first cut sheet of paper and mounted on one end of an open/close lever. Another set of transfer rollers is provided adjacent to a discharge aperture for the first cut sheet of paper. Opening and closing of the transfer rollers adjacent to the insertion aperture and opening and closing of the transfer rollers adjacent to the discharging aperture are performed by a common driving source.
    Type: Grant
    Filed: February 3, 1999
    Date of Patent: June 27, 2000
    Assignee: Seiko Epson Corporation
    Inventors: Akira Koyabu, Hiroyuki Nakayama, Susumu Hama
  • Patent number: 5895158
    Abstract: A printer having an ink jet type printing section for printing on a first cut sheet of paper having a first shape or a second cut sheet of paper having a second shape. A set of transfer rollers is provided adjacent to an insertion aperture for the first cut sheet of paper and mounted on one end of an open/close lever. Another set of transfer rollers is provided adjacent to a discharge aperture for the first cut sheet of paper. Opening and closing of the transfer rollers adjacent to the insertion aperture and opening and closing of the transfer rollers adjacent to the discharging aperture are performed by a common driving source.
    Type: Grant
    Filed: May 13, 1997
    Date of Patent: April 20, 1999
    Assignee: Seiko Epson Corporation
    Inventors: Akira Koyabu, Hiroyuki Nakayama, Susumu Hama
  • Patent number: 5605407
    Abstract: A printer is provided comprising a carriage on which recording head is mounted. Drive mechanisms for moving carriage in reciprocating motions an encoder having openings provided contiguously in the circumferential direction at fixed intervals, attached thereto, and which rotates as carriage moves. A position detector is provided in proximity to the encoder for detecting the encoder's detection-target unit and generates timing pulses in response thereto. A shielding plate is attached to carriage for blocking the encoder from the position detector at the home position. A processor detects the home position for carriage based upon a timing pulse pause time.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: February 25, 1997
    Assignee: Seiko Epson Corporation
    Inventors: Susumu Hama, Hiroshi Takizawa, Toshiaki Watanabe, Masahiro Kamijo, Manabu Shimizu
  • Patent number: 5572242
    Abstract: A highly reliable ink-jet printer or printing mechanism capable of consistent ink discharge in an on-demand type ink-jet printer. The printing mechanism is equipped with an ink-jet head having a plurality of ink nozzles that discharge ink drops and pressure generating elements corresponding to the nozzles, for applying pressure to the ink therein. A timer measures a preselected time period and a recovery processor controls recovery operations for each nozzle. The recovery operations are executed at prescribed time intervals during non-operation of the ink-jet head based on timer output. The recovery processor performs recovery processing when the power source is powered on. Further, an automatic power disconnection is performed when the number of consecutive recovery performed in response to the output of the timer reaches a prescribed maximum number.
    Type: Grant
    Filed: March 2, 1993
    Date of Patent: November 5, 1996
    Assignee: Seiko Epson Corporation
    Inventors: Masahiro Fujii, Susumu Hama, Hiroshi Takizawa, Masahiro Minowa
  • Patent number: 5139856
    Abstract: A plated ceramic or glass substrate having a plated surface, wherein an undercoat is formed between the surface of the substrate and the plating film. The undercoat includes nitrogen and at least one of chromium and titanium as major components thereof.
    Type: Grant
    Filed: December 20, 1989
    Date of Patent: August 18, 1992
    Assignee: NGK Insulators, Ltd.
    Inventors: Yukihisa Takeuchi, Azuma Yamamoto, Susumu Hama, Toshiki Goto
  • Patent number: 5069123
    Abstract: A print wheel printer includes a trigger unit casing and a main housing frame, a plurality of print wheels rotatably mounted on a print wheel shaft and having a corresponding ratchet wheel secured to one side of each print wheel. A plurality of rotatably mounted selective pawls are supported on the trigger unit casing for stopping the rotation of the print wheels at selected print wheel engagement positions wherein a corresponding pawl is rotated into position to engage a corresponding print wheel ratchet wheel. A rotatable reset lever is also mounted on the trigger unit casing for the purpose of returning the selective pawls to a print wheel disengagement position. The selective pawls and the reset lever are both supported on the trigger unit casing in a prealigned relationship and support means are provided on the main housing frame for supporting the set of print wheels.
    Type: Grant
    Filed: April 16, 1990
    Date of Patent: December 3, 1991
    Assignee: Seiko Epson Corporation
    Inventors: Sadao Murata, Yasuhiro Harada, Susumu Hama