Patents by Inventor Susumu Hama
Susumu Hama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9526791Abstract: A problem to be solved by the present invention is to provide a peptide compound for producing a drug delivery carrier capable of releasing a target substance in a weakly acidic pH environment. The present invention provides a peptide compound comprising a hydrophilic amino acid block and a hydrophobic amino acid block; [1] the peptide compound containing 24 to 36 amino acids in total; [2] the hydrophilic amino acid block containing 4 to 10 amino acids in total and having an average hydropathy index of ?3.0 to ?1.0; and [3] the hydrophobic amino acid block containing 20 to 32 amino acids in total, containing one or more His residues, and having an average hydropathy index of 1.0 to 2.5.Type: GrantFiled: October 21, 2013Date of Patent: December 27, 2016Assignee: Taiho Pharmaceutical Co., Ltd.Inventors: Kentaro Kogure, Susumu Hama
-
Patent number: 9186389Abstract: The present invention provides a nanoparticle and cell delivery agent, capable of releasing a target substance in a weakly acidic pH environment. Specifically, the present invention provides a nanoparticle comprising a peptide and a particle-forming component, the particle-forming component forming a liposome or a micelle, the peptide having a sequence with 2 to 8 units starting with His (histidine) and ending with an acidic amino acid, wherein each of the units may be identical or different.Type: GrantFiled: April 24, 2012Date of Patent: November 17, 2015Assignee: Taiho Pharmaceutical Co., Ltd.Inventors: Kentaro Kogure, Susumu Hama
-
Publication number: 20150250893Abstract: A problem to be solved by the present invention is to provide a peptide compound for producing a drug delivery carrier capable of releasing a target substance in a weakly acidic pH environment. The present invention provides a peptide compound comprising a hydrophilic amino acid block and a hydrophobic amino acid block; [1] the peptide compound containing 24 to 36 amino acids in total; [2] the hydrophilic amino acid block containing 4 to 10 amino acids in total and having an average hydropathy index of ?3.0 to ?1.0; and [3] the hydrophobic amino acid block containing 20 to 32 amino acids in total, containing one or more His residues, and having an average hydropathy index of 1.0 to 2.5.Type: ApplicationFiled: October 21, 2013Publication date: September 10, 2015Applicant: Taiho Pharmaceutical Co., Ltd.Inventors: Kentaro Kogure, Susumu Hama
-
Publication number: 20140044778Abstract: The present invention provides a nanoparticle and cell induction agent, capable of releasing a target substance in a weakly acidic pH environment. Specifically, the present invention provides a nanoparticle comprising a peptide and a particle-forming component, the particle-forming component forming a liposome or a micelle, the peptide having a sequence with 2 to 8 units starting with His (histidine) and ending with an acidic amino acid, wherein each of the units may be identical or different.Type: ApplicationFiled: April 24, 2012Publication date: February 13, 2014Applicant: TAIHO PHARMACEUTICAL CO., LTD.Inventors: Kentaro Kogure, Susumu Hama
-
Patent number: 6079887Abstract: A printer having an ink jet type printing section for printing on a first cut sheet of paper having a first shape or a second cut sheet of paper having a second shape. A set of transfer rollers is provided adjacent to an insertion aperture for the first cut sheet of paper and mounted on one end of an open/close lever. Another set of transfer rollers is provided adjacent to a discharge aperture for the first cut sheet of paper. Opening and closing of the transfer rollers adjacent to the insertion aperture and opening and closing of the transfer rollers adjacent to the discharging aperture are performed by a common driving source.Type: GrantFiled: February 3, 1999Date of Patent: June 27, 2000Assignee: Seiko Epson CorporationInventors: Akira Koyabu, Hiroyuki Nakayama, Susumu Hama
-
Patent number: 5895158Abstract: A printer having an ink jet type printing section for printing on a first cut sheet of paper having a first shape or a second cut sheet of paper having a second shape. A set of transfer rollers is provided adjacent to an insertion aperture for the first cut sheet of paper and mounted on one end of an open/close lever. Another set of transfer rollers is provided adjacent to a discharge aperture for the first cut sheet of paper. Opening and closing of the transfer rollers adjacent to the insertion aperture and opening and closing of the transfer rollers adjacent to the discharging aperture are performed by a common driving source.Type: GrantFiled: May 13, 1997Date of Patent: April 20, 1999Assignee: Seiko Epson CorporationInventors: Akira Koyabu, Hiroyuki Nakayama, Susumu Hama
-
Patent number: 5605407Abstract: A printer is provided comprising a carriage on which recording head is mounted. Drive mechanisms for moving carriage in reciprocating motions an encoder having openings provided contiguously in the circumferential direction at fixed intervals, attached thereto, and which rotates as carriage moves. A position detector is provided in proximity to the encoder for detecting the encoder's detection-target unit and generates timing pulses in response thereto. A shielding plate is attached to carriage for blocking the encoder from the position detector at the home position. A processor detects the home position for carriage based upon a timing pulse pause time.Type: GrantFiled: December 22, 1994Date of Patent: February 25, 1997Assignee: Seiko Epson CorporationInventors: Susumu Hama, Hiroshi Takizawa, Toshiaki Watanabe, Masahiro Kamijo, Manabu Shimizu
-
Patent number: 5572242Abstract: A highly reliable ink-jet printer or printing mechanism capable of consistent ink discharge in an on-demand type ink-jet printer. The printing mechanism is equipped with an ink-jet head having a plurality of ink nozzles that discharge ink drops and pressure generating elements corresponding to the nozzles, for applying pressure to the ink therein. A timer measures a preselected time period and a recovery processor controls recovery operations for each nozzle. The recovery operations are executed at prescribed time intervals during non-operation of the ink-jet head based on timer output. The recovery processor performs recovery processing when the power source is powered on. Further, an automatic power disconnection is performed when the number of consecutive recovery performed in response to the output of the timer reaches a prescribed maximum number.Type: GrantFiled: March 2, 1993Date of Patent: November 5, 1996Assignee: Seiko Epson CorporationInventors: Masahiro Fujii, Susumu Hama, Hiroshi Takizawa, Masahiro Minowa
-
Patent number: 5139856Abstract: A plated ceramic or glass substrate having a plated surface, wherein an undercoat is formed between the surface of the substrate and the plating film. The undercoat includes nitrogen and at least one of chromium and titanium as major components thereof.Type: GrantFiled: December 20, 1989Date of Patent: August 18, 1992Assignee: NGK Insulators, Ltd.Inventors: Yukihisa Takeuchi, Azuma Yamamoto, Susumu Hama, Toshiki Goto
-
Patent number: 5069123Abstract: A print wheel printer includes a trigger unit casing and a main housing frame, a plurality of print wheels rotatably mounted on a print wheel shaft and having a corresponding ratchet wheel secured to one side of each print wheel. A plurality of rotatably mounted selective pawls are supported on the trigger unit casing for stopping the rotation of the print wheels at selected print wheel engagement positions wherein a corresponding pawl is rotated into position to engage a corresponding print wheel ratchet wheel. A rotatable reset lever is also mounted on the trigger unit casing for the purpose of returning the selective pawls to a print wheel disengagement position. The selective pawls and the reset lever are both supported on the trigger unit casing in a prealigned relationship and support means are provided on the main housing frame for supporting the set of print wheels.Type: GrantFiled: April 16, 1990Date of Patent: December 3, 1991Assignee: Seiko Epson CorporationInventors: Sadao Murata, Yasuhiro Harada, Susumu Hama