Patents by Inventor Sven Kuehnert

Sven Kuehnert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of pain
    Patent number: 8017772
    Abstract: Substituted tetrahydropyrrolopyrazine compounds corresponding to the formula I: processes for their preparation, pharmaceutical compositions comprising these compounds and the use of these compounds for the treatment and/or inhibition of pain and other disorders or disease states at least partly mediated by KCNQ2/3 K+ channels.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: September 13, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Thomas Christoph, Stefan Oberboersch, Klaus Schiene, Gregor Bahrenberg, Robert Frank, Sven Kuehnert, Wolfgang Schroeder
  • Substituted propiolic acid amides and their use for producing drugs
    Patent number: 8008304
    Abstract: The present invention relates to substituted propiolic acid amides, methods for the production thereof, medicaments containing these compounds and the use thereof for producing medicaments.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: August 30, 2011
    Assignee: Grüenthal GmbH
    Inventors: Michael Haurand, Klaus Schiene, Sven Kühnert, Melanie Reich, Saskia Zemolka
  • Substituted imidazo[2,1-b]thiazole compounds and uses thereof
    Patent number: 7893069
    Abstract: Substituted imidazo[2,1-b]thiazole compounds corresponding to formula I, a method for producing them, pharmaceutical compositions containing them, and the use thereof for regularing mGluR5 receptors, or for treating or inhibiting disorders or disease states at least partially mediated by mGluR5 receptor such as pain, anxiety attacks, drug or alcohol dependency, and others.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: February 22, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Sven Kuehnert, Saskia Zemolka, Michael Haurand, Klaus Schiene
  • Substituted tetrahydropyrrolopyrazine compounds and the use thereof in pharmaceutical compositions
    Patent number: 7879858
    Abstract: Substituted tetrahydropyrrolopyrazine compounds corresponding to formula I a process for producing such compounds; and a method of using such compounds to treat or inhibit various disorders or disease states including pain, depression and anxiety.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: February 1, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Thomas Christoph, Stefan Oberboersch, Klaus Schiene, Gregor Bahrenberg, Robert Frank, Sven Kuehnert, Wolfgang Schroeder
  • Substituted thiazoles and their use for producing drugs
    Patent number: 7871999
    Abstract: The present invention relates to substituted thiazoles, to methods for the production thereof, to medicaments containing these compounds and to the use thereof for producing medicaments.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: January 18, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Michael Haurand, Klaus Schiene, Sven Kühnert, Melanie Reich
  • SUBSTITUTED 2-MERCAPTO-3-AMINOPYRIDINES AS KCNQ2/3 MODULATORS
    Publication number: 20100234428
    Abstract: The invention relates to substituted 2-mercapto-3-aminopyridines, methods for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Application
    Filed: March 10, 2010
    Publication date: September 16, 2010
    Applicant: GRUNENTHAL GMBH
    Inventors: Sven Kühnert, Beatrix Merla, Achim Kless, Gregor Bahrenberg, Wolfgang Schröder
  • SUBSTITUTED 3-AMINO-2-MERCAPTOQUINOLINES AS KCNQ2/3 MODULATORS
    Publication number: 20100234421
    Abstract: The invention relates to substituted 3-amino-2-mercaptoquinolines, to processes for their preparation, to medicaments containing these compounds and to the use of these compounds in the preparation of medicaments.
    Type: Application
    Filed: March 10, 2010
    Publication date: September 16, 2010
    Applicant: GRUNENTHAL GMBH
    Inventors: Sven KÜHNERT, Gregor Bahrenberg, Wolfgang Schröder
  • SUBSTITUTED 3-AMINOISOXAZOLOPYRIDINES AS KCNQ2/3 MODULATORS
    Publication number: 20100234419
    Abstract: The invention relates to substituted 3-aminoisoxazolopyridines, to processes for their preparation, to medicaments containing these compounds and to the use of these compounds in the preparation of medicaments.
    Type: Application
    Filed: March 10, 2010
    Publication date: September 16, 2010
    Applicant: GRUNENTHAL GMBH
    Inventors: Sven KÜHNERT, Gregor Bahrenberg, Wolfgang Schröder
  • SUBSTITUTED 2-MERCAPTOQUINOLINE-3-CARBOXAMIDES AS KCNQ2/3 MODULATORS
    Publication number: 20100234372
    Abstract: The invention relates to substituted 2-mercaptoquinoline-3-carboxamides, methods for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
    Type: Application
    Filed: March 10, 2010
    Publication date: September 16, 2010
    Applicant: GRUNENTHAL GMBH
    Inventors: Sven KÜHNERT, Gregor Bahrenberg, Achim Kless, Wolfgang Schröder
  • SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS
    Publication number: 20100234429
    Abstract: The invention relates to substituted nicotinamides, to processes for their preparation, to medicaments comprising these compounds and to the use of these compounds in the preparation of medicaments.
    Type: Application
    Filed: March 10, 2010
    Publication date: September 16, 2010
    Applicant: GRÜNENTHAL GMBH
    Inventors: Sven Kühnert, Beatrix Merla, Gregor Bahrenberg, Wolfgang Schröder
  • Substituted 4-(1,2,3,4-tetrahydroisoquinolin-2-yl)-4-oxobutyric acid amide as KCNQ2/3 modulators
    Publication number: 20100152234
    Abstract: The invention relates to substituted tetrahydroisoquinolinyl-4-oxobutyric acid amides, methods for the preparation thereof, medicinal products containing these compounds and the use of these compounds for the preparation of medicinal products.
    Type: Application
    Filed: December 11, 2009
    Publication date: June 17, 2010
    Applicant: GRUNENTHAL GMBH
    Inventors: Sven Kühnert, Gregor Bahrenberg, Beatrix Merla, Klaus Schiene, Wolfgang Schröder
  • Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators
    Publication number: 20100105722
    Abstract: Substituted tetrahydrothienopyridines corresponding to formula (1) in which A1 through A3 and R1 through R12 have defined meanings, pharmaceutical compositions comprising such compounds, a process for preparing such compounds and the use of such compounds in treatment or inhibition of conditions mediated by the KCNQ 2/3 K+ channel, e.g., pain.
    Type: Application
    Filed: October 23, 2009
    Publication date: April 29, 2010
    Applicant: GRUENENTHAL GmbH
    Inventors: Sven Kuehnert, Gregor Bahrenberg, Achim Kless, Beatrix Merla, Klaus Schiene, Wolfgang Schroeder
  • SUBSTITUTED TETRAHYDROPYRROLOPYRAZINE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT AND/OR INHIBITION OF PAIN
    Publication number: 20100004252
    Abstract: Substituted tetrahydropyrrolopyrazine compounds corresponding to the formula I: processes for their preparation, pharmaceutical compositions comprising these compounds and the use of these compounds for the treatment and/or inhibition of pain and other disorders or disease states at least partly mediated by KCNQ2/3 K+ channels.
    Type: Application
    Filed: September 11, 2009
    Publication date: January 7, 2010
    Applicant: GRUENENTHAL GmbH
    Inventors: Beatrix MERLA, Thomas CHRISTOPH, Stefan OBERBOERSCH, Klaus SCHIENE, Gregor BAHRENBERG, Robert FRANK, Sven KUEHNERT, Wolfgang SCHROEDER
  • Sutstituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of pain
    Patent number: 7625900
    Abstract: Substituted tetrahydropyrrolopyrazine compounds corresponding to the formula I: processes for their preparation, pharmaceutical compositions comprising these compounds and the use of these compounds for the treatment and/or inhibition of pain and other disorders or disease states at least partly mediated by KCNQ2/3 K+ channels.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: December 1, 2009
    Assignee: Gruenenthal GmbH
    Inventors: Beatrix Merla, Thomas Christoph, Stefan Oberboersch, Klaus Schiene, Gregor Bahrenberg, Robert Frank, Sven Kuehnert, Wolfgang Schroeder
  • Substituted Tetrahydropyrrolopyrazine Compounds and the Use Thereof in Pharmaceutical Compositions
    Publication number: 20090258880
    Abstract: Substituted tetrahydropyrrolopyrazine compounds corresponding to formula I a process for producing such compounds; and a method of using such compounds to treat or inhibit various disorders or disease states including pain, depression and anxiety.
    Type: Application
    Filed: April 17, 2009
    Publication date: October 15, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix MERLA, Thomas Christoph, Stefan Oberboersch, Klaus Schiene, Gregor Bahrenberg, Robert Frank, Sven Kuehnert, Wolfgang Schroeder
  • Substituted Tetrahydroimidazopyridine Compounds and the Use Thereof in the Treatment of Pain and Other Conditions
    Publication number: 20090186902
    Abstract: Substituted tetrahydroimidazopyridine compounds corresponding to formula I: in which R1, R2 and R3 have defined meanings, processes for preparing such compounds, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain, epilepsy, migraine, anxiety or urinary incontinence.
    Type: Application
    Filed: January 21, 2009
    Publication date: July 23, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix MERLA, Stefan Oberboersch, Sven Kuehnert, Gregor Bahrenberg, Achim Kless
  • para-alkyl-substituted N-(4-hydroxy-3-methoxy-benzyl)-cinnamamides, pharmaceutical compositions and uses thereof
    Patent number: 7541495
    Abstract: para-Alkyl-substituted N-(4-hydroxy-3-methoxybenzyl)-cinnamic acid amide compounds, processes for the preparation thereof, pharmaceutical compositions containing these compounds, and the use of these compounds for treating or inhibiting specific diseases or disorders.
    Type: Grant
    Filed: February 12, 2007
    Date of Patent: June 2, 2009
    Assignee: Gruenenthal GmbH
    Inventors: Sven Kuehnert, Robert Frank, Ruth Jostock
  • SUBSTITUTED NICOTINAMIDE COMPOUNDS AND USES THEREOF
    Publication number: 20090076086
    Abstract: Substituted nicotinamide compounds corresponding to formula I a process for their preparation, pharmaceutical compositions containing these compounds, and the use thereof for the treatment or inhibition conditions such as pain, epilepsy, migraine, anxiety states, or urinary incontinence.
    Type: Application
    Filed: September 17, 2008
    Publication date: March 19, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Beatrix Merla, Sven Kuehnert, Robert Frank, Dagmar Kaulartz, Wolfgang Schroeder, Gregor Bahrenberg, Klaus Schiene
  • Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof
    Publication number: 20090069320
    Abstract: Substituted 4-amino-quinazoline compounds corresponding to formula I methods for their production, pharmaceutical compositions containing these compounds as active agents, and the uses thereof for treating or inhibiting disorders or disease states.
    Type: Application
    Filed: September 15, 2008
    Publication date: March 12, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Melanie REICH, Stefan Oberboersch, Sven Kuehnert, Michael Haurand, Klaus Schiene
  • Substituted Imidazo[2,1-b]thiazole Compounds and Uses Thereof
    Publication number: 20090005399
    Abstract: Substituted imidazo[2,1-b]thiazole compounds corresponding to formula I, a method for producing them, pharmaceutical compositions containing them, and the use thereof for regularing mGluR5 receptors, or for treating or inhibiting disorders or disease states at least partially mediated by mGluR5 receptor such as pain, anxiety attacks, drug or alcohol dependency, and others.
    Type: Application
    Filed: September 9, 2008
    Publication date: January 1, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Sven KUEHNERT, Saskia ZEMOLKA, Michael HAURAND, Klaus SCHIENE