Patents by Inventor Tadayoshi Okumura

Tadayoshi Okumura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sense oligonucleotide capable of controlling the expression of INOS and composition comprising the same
    Patent number: 9464292
    Abstract: The invention relates to sense oligonucleotide having a sequence complementary to a single-stranded RNA (antisense transcript) having a sequence complementary to mRNA of iNOS gene in order to control expression of iNOS (inducible nitric oxide synthase). The sense oligonucleotide of the present invention can control expression of iNOS and is useful for biological defense and treatment and prevention of diseases related to excessive production of NO, such as cancerogenesis, inflammatory disease, endotoxin shock by bacterial infection and the like.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: October 11, 2016
    Assignees: AMINO UP CHEMICAL CO., LTD, KANSAI MEDICAL UNIVERSITY
    Inventors: Tadayoshi Okumura, Mikio Nishizawa, Yasuo Kamiyama, Koji Wakame, Takehito Miura
  • SENSE OLIGONUCLEOTIDE CAPABLE OF CONTROLLING THE EXPRESSION OF INOS AND COMPOSITION COMPRISING THE SAME
    Publication number: 20150191733
    Abstract: The invention relates to sense oligonucleotide having a sequence complementary to a single-stranded RNA (antisense transcript) having a sequence complementary to mRNA of iNOS gene in order to control expression of iNOS (inducible nitric oxide synthase). The sense oligonucleotide of the present invention can control expression of iNOS and is useful for biological defense and treatment and prevention of diseases related to excessive production of NO, such as cancerogenesis, inflammatory disease, endotoxin shock by bacterial infection and the like.
    Type: Application
    Filed: December 12, 2014
    Publication date: July 9, 2015
    Applicants: AMINO UP CHEMICAL CO., LTD, KANSAI MEDICAL UNIVERSITY
    Inventors: Tadayoshi OKUMURA, Mikio NISHIZAWA, Yasuo KAMIYAMA, Koji WAKAME, Takehito MIURA
  • Method for controlling the amount of gene product, and agent for controlling the amount of gene product
    Patent number: 8975023
    Abstract: The invention relates to a method of intracellularly controlling amounts of gene products, which can increase an amount of gene product intracellularly, comprising a step of introducing into the cell a substance having a sequence complementary to the base sequence of mRNA corresponding to the gene product, its precursor or another substance which can have equivalent action in the cell.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: March 10, 2015
    Assignees: Amino Up Chemical Co., Ltd, Kansai Medical University
    Inventors: Tadayoshi Okumura, Mikio Nishizawa, Yasuo Kamiyama, Koji Wakame, Takehito Miura
  • Sense oligonucleotide capable of controlling the expression of iNOS and composition comprising the same
    Patent number: 8927704
    Abstract: The invention relates to sense oligonucleotide having a sequence complementary to a single-stranded RNA (antisense transcript) having a sequence complementary to mRNA of iNOS gene in order to control expression of iNOS (inducible nitric oxide synthase). The sense oligonucleotide of the present invention can control expression of iNOS and is useful for biological defense and treatment and prevention of diseases related to excessive production of NO, such as cancerogenesis, inflammatory disease, endotoxin shock by bacterial infection and the like.
    Type: Grant
    Filed: June 7, 2007
    Date of Patent: January 6, 2015
    Assignees: Amino Up Chemical Co., Ltd, Kansai Medical University
    Inventors: Tadayoshi Okumura, Mikio Nishizawa, Yasuo Kamiyama, Koji Wakame, Takehito Miura
  • METHOD FOR CONTROLLING THE AMOUNT OF GENE PRODUCT, AND AGENT FOR CONTROLLING THE AMOUNT OF GENE PRODUCT
    Publication number: 20130177909
    Abstract: The invention relates to a method of intracellularly controlling amounts of gene products, which can increase an amount of gene product intracellularly, comprising a step of introducing into the cell a substance having a sequence complementary to the base sequence of mRNA corresponding to the gene product, its precursor or another substance which can have equivalent action in the cell.
    Type: Application
    Filed: February 19, 2013
    Publication date: July 11, 2013
    Applicants: KANSAI MEDICAL UNIVERSITY, AMINO UP CHEMICAL CO., LTD.
    Inventors: Tadayoshi OKUMURA, Mikio NISHIZAWA, Yasuo KAMIYAMA, Koji WAKAME, Takehito MIURA
  • Method for controlling the amount of gene product, and agent for controlling the amount of gene product
    Patent number: 8399424
    Abstract: The invention relates to a method of intracellularly controlling amounts of gene products, which can increase an amount of gene product intracellularly, comprising a step of introducing into the cell a substance having a sequence complementary to the base sequence of mRNA corresponding to the gene product, its precursor or another substance which can have equivalent action in the cell.
    Type: Grant
    Filed: June 7, 2007
    Date of Patent: March 19, 2013
    Assignees: Amino Up Chemical Co., Ltd, Kansai Medical University
    Inventors: Tadayoshi Okumura, Mikio Nishizawa, Yasuo Kamiyama, Koji Wakame, Takehito Miura
  • SENSE OLOGONUCLEOTIDE CAPABLE OF CONTROLLING THE EXPRESSION OF iNOS AND COMPOSITION COMPRISING THE SAME
    Publication number: 20100248364
    Abstract: The invention relates to sense oligonucleotide having a sequence complementary to a single-stranded RNA (antisense transcript) having a sequence complementary to mRNA of iNOS gene in order to control expression of iNOS (inducible nitric oxide synthase). The sense oligonucleotide of the present invention can control expression of iNOS and is useful for biological defense and treatment and prevention of diseases related to excessive production of NO, such as cancerogenesis, inflammatory disease, endotoxin shock by bacterial infection and the like.
    Type: Application
    Filed: June 7, 2007
    Publication date: September 30, 2010
    Applicant: Amino Up Chemical Co., Ltd.
    Inventors: Tadayoshi Okumura, Mikio Nishizawa, Yasuo Kamiyama, Koji Wakame, Takehito Miura
  • METHOD FOR CONTROLLING THE AMOUNT OF GENE PRODUCT, AND AGENT FOR CONTROLLING THE AMOUNT OF GENE PRODUCT
    Publication number: 20100227318
    Abstract: The invention relates to a method of intracellularly controlling amounts of gene products, which can increase an amount of gene product intracellularly, comprising a step of introducing into the cell a substance having a sequence complementary to the base sequence of mRNA corresponding to the gene product, its precursor or another substance which can have equivalent action in the cell.
    Type: Application
    Filed: June 7, 2007
    Publication date: September 9, 2010
    Applicants: AMINO UP CHEMICAL CO., LTD., KANSAI MEDICAL UNIVERSITY
    Inventors: Tadayoshi Okumura, Mikio Nishizawa, Yasuo Kamiyama, Koji Wakame, Takehito Miura