Patents by Inventor Takafumi Nakamura
Takafumi Nakamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20180208904Abstract: It is an object of the present invention to provide utilization of a UCA1 gene that is a host regulatory factor that enhances replication and/or propagation of a vaccinia virus, in order to effectively carry out cancer virotherapy using the vaccinia virus. The present invention relates to: a method for predicting and evaluating the cancer therapeutic effects of a vaccinia virus, which comprises measuring the expression of a UCA1 gene in the cancer cells of a cancer patient, and then predicting that a vaccinia virus exhibits cancer therapeutic effects on the patient, when the UCA1 gene has been expressed therein; and a vaccinia virus into which a UCA1 gene has been expressibly introduced.Type: ApplicationFiled: July 22, 2016Publication date: July 26, 2018Inventors: Takafumi Nakamura, Kousuke Horita, Hajime Kurosaki, Motomu Nakatake
-
Patent number: 10023284Abstract: An outboard motor includes an electric power source, a mechanical power source auxiliary machine, an electric circuit, an electric supply port, and a switch. The mechanical power source auxiliary machine assists driving a mechanical power source. The electric circuit electrically connects the electric power source and the mechanical power source auxiliary machine. The electric supply port is electrically connected to the electric power source through the electric circuit, and supplies an electric power to an accessory device to be connected thereto. The switch is disposed between the electric power source and the electric supply port in the electric circuit, and is switchable between an on state and an off state. The switch allows a flow of an electric current when switched to the on state, and interrupts the flow of the electric current when switched to the off state.Type: GrantFiled: December 5, 2017Date of Patent: July 17, 2018Assignee: YAMAHA HATSUDOKI KABUSHIKI KAISHAInventors: Takafumi Nakamura, Yuki Yamaguchi
-
Publication number: 20180136174Abstract: A preparative chromatograph for collecting target components in a sample temporally separated in a column of a chromatograph in respective preparative containers is provided with: a detection unit having a flow cell accommodated in a housing and a detector for detecting a component that passes through the flow cell; a first pipe that connects the column and an inlet end of the flow cell; a flow path switching unit accommodated in the housing and configured to selectively flow the components that passed through the flow cell through a preparative flow path that is a flow path connected to the preparative containers or a waste liquid flow path; and a second pipe accommodated in the housing and connecting an outlet end of the flow cell and the flow path switching unit.Type: ApplicationFiled: June 1, 2015Publication date: May 17, 2018Inventors: Takafumi Nakamura, Tadayuki Yamaguchi, Yusuke Nagai
-
Publication number: 20180058586Abstract: A buffer ring includes an annular body portion 11 that makes close contact with a side wall face 131b of an annular groove 131; an inner peripheral lip 12 that extends toward a sealed fluid side O from an inner peripheral end portion of the body portion 11; and an outer peripheral lip 13 that extends toward the sealed fluid side O from an outer peripheral end portion of the body portion 11 and having an outer peripheral end portion making close contact with a groove bottom face 131a of the annular groove 131, the outer peripheral lip 13 being lower in stiffness than the inner peripheral lip 12, wherein a plurality of protrusions 14 that make close contact with the groove bottom face 131a of the annular groove 131 are provided on an outer peripheral face of the body portion 11 at intervals in a circumferential direction.Type: ApplicationFiled: October 24, 2017Publication date: March 1, 2018Inventor: Takafumi NAKAMURA
-
Publication number: 20170340687Abstract: The present invention provides a genetically recombinant vaccinia virus effective in preventing or treating cancer. Specifically, the present invention provides a vaccinia virus comprising two polynucleotides, a polynucleotide encoding IL-7 and a polynucleotide encoding IL-12; a combination kit of two vaccinia viruses, a vaccinia virus comprising a polynucleotide encoding IL-7 and a vaccinia virus comprising a polynucleotide encoding IL-12; and use of the two vaccinia viruses in combination.Type: ApplicationFiled: July 31, 2017Publication date: November 30, 2017Applicants: Astellas Pharma Inc., National University Corporation Tottori UniversityInventors: Shinsuke Nakao, Tatsuya Kawase, Takafumi Nakamura
-
Patent number: 9809803Abstract: This invention provides a vaccinia virus that grows specifically in a cancer cell and damages such cancer cell and the use of such virus for treatment of cancer. Such mitogen-activated protein kinase-dependent vaccinia virus strain lacks functions of vaccinia virus growth factor (VGF) and O1L, it does not grow in normal cells but grows specifically in cancer cells, and it has oncolytic properties that specifically damage cancer cells.Type: GrantFiled: November 20, 2014Date of Patent: November 7, 2017Assignees: National University Corporation Tottori University, The Chemo-Sero-Therapeutic Research InstituteInventor: Takafumi Nakamura
-
Patent number: 9748667Abstract: A terminal device includes a first memory that stores a position of each of antennas included in a main body of a terminal device for each of holding manners for the main body of the terminal device, a second memory, a processor coupled to the second memory, configured to detect a holding manner for the main body of the terminal device including the antennas, detect a shape indicating a shadow of an object pointing to a surface of the terminal device, identify a holding hand that holds the main body of the terminal device, based on the detected shape, and switch an antenna which overlaps with the holding hand to another antenna based on the identified holding hand and the position of each antenna stored in the first memory, the antenna corresponding to the detected holding manner.Type: GrantFiled: April 24, 2015Date of Patent: August 29, 2017Assignee: FUJITSU LIMITEDInventor: Takafumi Nakamura
-
Publication number: 20160281066Abstract: This invention provides a vaccinia virus that grows specifically in a cancer cell and damages such cancer cell and the use of such virus for treatment of cancer. Such mitogen-activated protein kinase-dependent vaccinia virus strain lacks functions of vaccinia virus growth factor (VGF) and O1L, it does not grow in normal cells but grows specifically in cancer cells, and it has oncolytic properties that specifically damage cancer cells.Type: ApplicationFiled: November 20, 2014Publication date: September 29, 2016Applicants: National University Corporation Tottori University, The Chemo-Sero-Therapeutic Research InstituteInventor: Takafumi Nakamura
-
Patent number: 9188572Abstract: A liquid chromatograph analyzing device, which without an analyst having to set complicated processing conditions before measuring a sample, is able to processes unaffected by fluctuations in room temperature and appearance of ghost peaks. In a liquid chromatograph analyzing device, an automatic sampler, a liquid sending pump, a column oven and a detection device are controlled by a calculation processing device. In addition to chromatograph creation unit, which creates chromatograms of a sample based on input detection signals, the calculation processing device has a correction parameter holding section and correction formula setting unit. The correction formula setting unit provides to the liquid chromatograph analyzing device a functionality for the analyst to set correction formulas for incorporating in the chromatograms created by the chromatograph creation unit changes to environmental conditions such as fluctuations in temperature around the liquid chromatograph analyzing device.Type: GrantFiled: April 26, 2013Date of Patent: November 17, 2015Assignee: Shimadzu CorporationInventor: Takafumi Nakamura
-
Publication number: 20150318625Abstract: A terminal device includes a first memory that stores a position of each of antennas included in a main body of a terminal device for each of holding manners for the main body of the terminal device, a second memory, a processor coupled to the second memory, configured to detect a holding manner for the main body of the terminal device including the antennas, detect a shape indicating a shadow of an object pointing to a surface of the terminal device, identify a holding hand that holds the main body of the terminal device, based on the detected shape, and switch an antenna which overlaps with the holding hand to another antenna based on the identified holding hand and the position of each antenna stored in the first memory, the antenna corresponding to the detected holding manner.Type: ApplicationFiled: April 24, 2015Publication date: November 5, 2015Inventor: Takafumi Nakamura
-
Patent number: 9128073Abstract: The invention provides a needle moving device which can detect a fault in a signal provided by a system controller to a performing device. An X-direction driving motor (4a) and a Y-direction driving motor (4b) in a driving portion (4) of an autosampler (1a) are provided with encoders (12a, 12b) for measuring moving distances of a needle (2) in respective directions from rotation numbers of the respective driving motors (4a and 4b). A determining portion (20) provided to a system controller (1b) locates a position of the needle (2) after the movement based on signals from the encoders (12a, 12b) and determines whether the position is a position of a designated sample vessel.Type: GrantFiled: July 16, 2010Date of Patent: September 8, 2015Assignee: SHIMADZU CORPORATIONInventor: Takafumi Nakamura
-
Publication number: 20150123351Abstract: A buffer ring includes an annular body portion 11 that makes close contact with a side wall face 131b of an annular groove 131; an inner peripheral lip 12 that extends toward a sealed fluid side O from an inner peripheral end portion of the body portion 11; and an outer peripheral lip 13 that extends toward the sealed fluid side O from an outer peripheral end portion of the body portion 11 and having an outer peripheral end portion making close contact with a groove bottom face 131a of the annular groove 131, the outer peripheral lip 13 being lower in stiffness than the inner peripheral lip 12, wherein a plurality of protrusions 14 that make close contact with the groove bottom face 131a of the annular groove 131 are provided on an outer peripheral face of the body portion 11 at intervals in a circumferential direction.Type: ApplicationFiled: March 26, 2013Publication date: May 7, 2015Applicant: NOK CorporationInventor: Takafumi Nakamura
-
Patent number: 8963194Abstract: A light emitting device includes a light emitting layer having a first side and a second side opposite to the first side; an upper electrode; a current diffusion layer provided between the light emitting layer and the upper electrode and including a first layer on the first side of the light emitting layer and a second layer on a side of the upper electrode, the second layer having a carrier concentration higher than a concentration of the first layer, a recess being formed in a non-forming region of the upper electrode of the current diffusion layer so that a width of the recess decreases toward the light emitting layer, a sidewall of the second layer being at least a part of a sidewall of the recess; and a reflecting layer provided on the second side of the light emitting layer, the upper electrode being provided on the second layer, and the light emitting layer and the current diffusion layer being made of a III-V group compound semiconductor, respectively.Type: GrantFiled: June 11, 2013Date of Patent: February 24, 2015Assignee: Kabushiki Kaisha ToshibaInventors: Chisato Furukawa, Takafumi Nakamura
-
Patent number: 8770046Abstract: An autosampler is provided with a needle, a measuring pump which sucks and discharges liquid through the needle, a movement mechanism for the needle, and an injection port which has a needle sealing surface. A sample liquid is sucked into the needle and then the sample liquid discharged with the tip of the needle pressed to the needle sealing surface. When cleaning the needle sealing surface, a cleaning liquid within the injection port is sucked and then the cleaning liquid is discharged and sucked into the injection port at a position at which the tip of the needle does not make contact with the needle sealing surface. Alternatively, after the cleaning liquid is discharged into the injection port, the needle may be caused to perform an up and down motion such that the tip of the needle contacts the needle sealing surface and then is lifted.Type: GrantFiled: September 1, 2010Date of Patent: July 8, 2014Assignee: Shimadzu CorporationInventors: Yoshiaki Maeda, Kenichi Yasunagi, Takafumi Nakamura
-
Publication number: 20140175475Abstract: A light emitting device and a method for manufacturing the same are provided. The light emitting device includes: a first substrate having electrical conductivity; a foundation layer; a bonded metal layer configured to bond one major surface of the foundation layer to the first substrate; a mask layer provided on the other major surface of the foundation layer, having a window, and made of an insulator; and a multilayer body selectively provided on the foundation layer exposed to the window, and including a light emitting layer.Type: ApplicationFiled: February 25, 2014Publication date: June 26, 2014Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Chisato Furukawa, Takafumi Nakamura
-
Publication number: 20140149623Abstract: A disclosed information processing apparatus includes: a first processing unit; and a second processing unit that is in either of an operational state and a suspended state. The first processing unit and the second processing unit are coupled by a first signal line through which a first signal that represents a state of the second processing unit passes and by a second signal line through which a second signal that causes an interrupt to the second processing unit passes. The second processing unit outputs the first signal according to a state of the second processing unit. The first processing unit determines, based on the first signal, whether the first processing unit causes the second processing unit to resume. When the first processing unit causes the second processing unit to resume, the first processing unit outputs the second signal, and the second processing unit resumes, upon receiving the second signal.Type: ApplicationFiled: September 24, 2013Publication date: May 29, 2014Applicant: Fujitsu Mobile communications LimitedInventor: Takafumi NAKAMURA
-
Publication number: 20130270604Abstract: A light emitting device includes a light emitting layer made of semiconductor; an upper electrode including a bonding electrode capable of connecting a wire thereto and a thin-wire electrode surrounding the bonding electrode with a spacing and including a junction with the bonding electrode, and a current diffusion layer provided between the light emitting layer and the upper electrode and made of semiconductor, the current diffusion layer including a recess that is formed in a non-forming region of the upper electrode and capable of emitting light emitted from the light emitting layer.Type: ApplicationFiled: June 11, 2013Publication date: October 17, 2013Inventors: Chisato Furukawa, Takafumi Nakamura
-
Publication number: 20130238254Abstract: A liquid chromatograph analyzing device, which without an analyst having to set complicated processing conditions before measuring a sample, is able to processes unaffected by fluctuations in room temperature and appearance of ghost peaks. In a liquid chromatograph analyzing device, an automatic sampler, a liquid sending pump, a column oven and a detection device are controlled by a calculation processing device. In addition to chromatograph creation unit, which creates chromatograms of a sample based on input detection signals, the calculation processing device has a correction parameter holding section and correction formula setting unit. The correction formula setting unit provides to the liquid chromatograph analyzing device a functionality for the analyst to set correction formulas for incorporating in the chromatograms created by the chromatograph creation unit changes to environmental conditions such as fluctuations in temperature around the liquid chromatograph analyzing device.Type: ApplicationFiled: April 26, 2013Publication date: September 12, 2013Applicant: Shimadzu CorporationInventor: Takafumi NAKAMURA
-
Patent number: 8482024Abstract: A light emitting device includes a light emitting layer made of semiconductor; an upper electrode including a bonding electrode capable of connecting a wire thereto and a thin-wire electrode surrounding the bonding electrode with a spacing and including a junction with the bonding electrode, and a current diffusion layer provided between the light emitting layer and the upper electrode and made of semiconductor, the current diffusion layer including a recess that is formed in a non-forming region of the upper electrode and capable of emitting light emitted from the light emitting layer.Type: GrantFiled: February 3, 2009Date of Patent: July 9, 2013Assignee: Kabushiki Kaisha ToshibaInventors: Chisato Furukawa, Takafumi Nakamura
-
Patent number: 8418533Abstract: The present invention provides an analyzing system with which a serial analysis inclusive of a pretreatment can be easily performed in a liquid chromatograph, and even unskilled users can perform a desired analysis. The analyzing system according to the present invention includes: an edit screen display section 31 for displaying an edit screen for allowing a user to create a pretreatment program using an external variable; a batch table display section 32 for displaying a batch table used for serially executing a plurality of analyses, the batch table having an external-variable setting field for allowing the user to enter the aforementioned external variable; and a serial analysis execution section 33 for serially executing each of the analyses inclusive of a pretreatment operation of an auto-sampler according to the pretreatment program and the batch table.Type: GrantFiled: March 7, 2011Date of Patent: April 16, 2013Assignee: Shimadzu CorporationInventor: Takafumi Nakamura