Abstract: A bioactive cement comprises a filler consisting of nonalkali glass powder containing Ca, monomer containing hydrophilic dimethacrylate, a polymerization starter, and a polymerization promotor. The nonalkali glass powder containing Ca comprises a composition by weight of 40-50% CaO, 30-40% SiO.sub.2, 10-20% P.sub.2 O.sub.5, 0-10% MgO, and 0-2% CaF.sub.2. The hydrophilic dimethacrylate is 2,2-bis[4-(3-methacryloxy-2-hydroxy propoxy)phenyl]propane. The bioactive cement is capable of forming a hydroxyapatite layer on a surface of a hardened cement body when the hardened cement body is brought into contact with body fluid.

Abstract: An excellent bioactive cement is provided which can chemically and firmly bond to teeth or bones of living bodies, adapt the shape of defected portions of bones or teeth of living bodies, harden quickly, and exhibit high initial strength, without forming inflammation to the surrounding tissue of living bodies. The bioactive cement is composed of glass powder comprising Ca as a main constituent, and an aqueous solution of ammonium phosphate as a hardening liquid for the glass powder, and is economical and stable without loosing the fixation between the artificial biomaterial and the bones or teeth of living bodies nor degradation thereof in the living bodies during a long period of use in the living bodies.

Abstract: Bone-like, bioactive hydroxyapatite films are formed on any substrates of inorganic, metallic or organic material, by soaking a glass mainly comprising CaO and SiO.sub.2 and a substrate arranged in a face-to-face relation, a predetermined distance apart, in an aqueous solution substantially saturated or supersaturated with constituent ions of hydroxyapatite.