Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis

Abstract: A nitride crystal which encircles an outer periphery of a seed crystal, the nitride crystal in an embodiment includes: a first partial region, and a second partial region that has optical characteristics different from those of the first partial region and has optical characteristics which indicate the crystal orientation.

Abstract: A vehicle controller performs a throttle-valve-late-close control in which the throttle valve is held open until a delay time has passed after the fuel cut is started, and an EGR-valve-open-close control in which the EGR valve is repeatedly opened and closed. Then, the throttle valve is closed and the EGR valve is opened. In a period from a latter period of an exhaust stroke to a preceding period of an intake stroke, a valve-overlap control is executed so that a variable valve timing controller is controlled to make both an intake valve and an exhaust valve opened. A pumping loss of an engine is sufficiently reduced and an energy-regenerate efficiency can be effectively improved.

Abstract: There is disclosed a method of controlling an electron gun without causing decreases in brightness of the electron beam if a current-limiting aperture cannot be used. The electron gun (10) has a cathode (11), a Wehnelt electrode (12), a control electrode (13), an anode (14), and a controller (22). The Wehnelt electrode (12) has a first opening (12c) in which the tip of the cathode is inserted, and focuses thermal electrons emitted from the tip of the cathode (11). The thermal electrons emitted from the tip of the cathode (11) are caused to pass into a second opening (13c) by the control electrode (13). The anode (14) accelerates the thermal electrons emitted from the cathode (11) such that the thermal electrons passed through the second opening (13c) pass through a third opening (14b) and impinge as an electron beam (B1) on a powdered sample (8).

Abstract: The present processing apparatus includes an extraction unit and a control unit. The extraction unit extracts a job group including an extraction job and a subsequent job from a plurality of scheduled jobs, the plurality of scheduled jobs being included in a second operation, the second operation being scheduled in a second period which is after a first period in which a first operation is scheduled, the extraction job extracting a data group and being included in the plurality of scheduled jobs, and the subsequent job processing on the data group within a range of the data group. The control unit executes jobs in the extracted job group in the first period. Accordingly, the second operation can be completed by the start of the first operation.

Abstract: Embodiments of the disclosure relate to tetrahydropyrazolopyrimidine compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.

Abstract: A gallium nitride crystal having a hexagonal crystal structure includes a first region located on an inner side of a cross section intersecting c-axis of the hexagonal crystal structure, and a second region surrounding at least a part of the outer periphery of the first region in the cross section. An emission spectrum of each of the first region and the second region with electron beam or ultraviolet light excitation has a first peak including a band edge emission of gallium nitride and a second peak located in a longer wavelength area than the first peak. A peak intensity of the first peak is smaller than a peak intensity of the second peak in the first region, and a peak intensity of the first peak is greater than a peak intensity of the second peak in the second region.

Abstract: A group 13 nitride crystal has a hexagonal crystal structure and at least contains nitrogen atom and at least a kind of metal atoms selected from a group consisting of B, Al, Ga, In, and Tl. The group 13 nitride crystal includes a first region located at an inner side of a cross section intersecting a c-axis, and a second region surrounding at least a part of an outer periphery of the first region, having a thickness larger than a maximum diameter of the first region, and having a carrier density higher than that of the first region.

Abstract: A nitride crystal which encircles an outer periphery of a seed crystal, the nitride crystal in an embodiment includes: a first partial region, and a second partial region that has optical characteristics different from those of the first partial region and has optical characteristics which indicate the crystal orientation.

Abstract: The present invention provides compounds of Formula I: along with pharmaceutical compositions containing the same, and methods of use thereof in subjects in need of treatment.

Abstract: A vehicle control apparatus uses a travel mode selection unit to select between an EV travel mode, an engine travel mode, and an engine generation mode depending on comparisons between an engine generated power cost, an EV effect, and a surplus electric energy. In such manner, according to a travel condition of a vehicle, an appropriate travel mode is selected for an improvement of fuel consumption efficiency. The vehicle control apparatus also computes a fuel consumption decrease or a fuel consumption increase for each of a plurality of travel modes based on an engine efficiency and an MG-INV efficiency. In such manner, fuel consumption increase/decrease for every travel mode may be computed.

Abstract: A vehicle control apparatus computes a fuel consumption decrease or a fuel consumption increase for each of a plurality of travel modes. The vehicle control apparatus includes a control section that calculates an engine efficiency of an engine and an MG-INV efficiency which is a combined efficiency of a motor generator and an inverter. The engine efficiency is calculated based on an engine power and an ideal fuel consumption line. The MG-INV efficiency is calculated based on an MG power. As such, based on the engine efficiency and the MG-INV efficiency, the control section computes the per-unit-electric-power fuel consumption decrease or the per-unit-electric-power fuel consumption increase.

Abstract: An information processing apparatus includes a storage unit and a processing unit. The storage unit is configured to store therein a first execution time and a second execution time longer than the first execution time. The first execution time is a time expected to be taken to execute a first job included in a first job group. The processing unit is configured to determine in which time period an execution start time of the first job is included. The execution start time is a time at which execution of the first job is to be started. The processing unit is configured to select, as a predicted execution time of the first job, one of the first execution time and the second execution time based on a result of the determination. The processing unit is configured to perform scheduling of the first job group based on the predicted execution time.

Abstract: A method for producing a group 13 nitride crystal, comprises a crystal growth step of reacting nitrogen and a mixed melt containing at least a group 13 metal and at least one of an alkali metal and an alkaline earth metal, in the mixed melt, to grow a nitride crystal on a seed crystal, wherein at least one of the mixed melt and the seed crystal is rotated in the crystal growth step, a relative speed between the mixed melt and the seed crystal in the crystal growth step is repeatedly fluctuated in accordance with one or a plurality of types of predetermined patterns, and a maximum value of the relative speed indicated by the pattern is 0.01 m/s or more.

Abstract: An apparatus for controlling automatic stop/restart of an engine, includes: an automatic-stop/restart-control-unit which stops/restarts the engine; a brake-pressure-detection-unit which detects brake pressure in a brake system and controls the brake pressure to perform anti-skid control; a first-determination-unit which determines whether the brake pressure is not less than a first-threshold; a second-determination-unit which determines whether the brake pressure is not less than a second-threshold larger than the-first threshold; a stop-allowing-unit which allows the automatic-stop/restart-control-unit to stop the engine while the engine operates, when the first-determination-unit determines that the brake pressure is not less than the first-threshold and the second-determination-unit determines that the brake pressure is less than the second-threshold; and a stop-inhibiting-unit which inhibits the automatic-stop/restart-control-unit from stopping the engine while the engine operates, when the-first-determin

Abstract: The present invention provides compounds of Formula I: along with pharmaceutical compositions containing the same, and methods of use thereof in subjects in need of treatment.

Abstract: A vehicle controller performs a throttle-valve-late-close control in which the throttle valve is held open until a delay time has passed after the fuel cut is started, and an EGR-valve-open-close control in which the EGR valve is repeatedly opened and closed. Then, the throttle valve is closed and the EGR valve is opened. In a period from a latter period of an exhaust stroke to a preceding period of an intake stroke, a valve-overlap control is executed so that a variable valve timing controller is controlled to make both an intake valve and an exhaust valve opened. A pumping loss of an engine is sufficiently reduced and an energy-regenerate efficiency can be effectively improved.

Abstract: The present invention provides compounds of Formula I: along with pharmaceutical compositions containing the same, and methods of use thereof in subjects in need of treatment.

Abstract: A group 13 nitride crystal having a hexagonal crystal structure contains at least a nitrogen atom and at least one metal atom selected from a group consisting of B, Al, Ga, In and Tl. Dislocation density of basal plane dislocations in a cross section parallel to a c-axis is 104 cm?2 or more.

Abstract: An engine automatic stop and restart control apparatus is provided. The apparatus includes a control unit which stops and restarts an engine, an actual axle torque change speed calculation unit which calculates change speed in actual axle torque that is actually generated when the engine is restarted, an ideal axle torque change speed calculation unit which calculates change speed in ideal axle torque that corresponds to engine torque generated by the engine, a change speed difference calculation unit which calculates a change speed difference that is a difference between the change speed in actual axle torque and the change speed in ideal axle torque, and a vibration suppression control unit which executes a vibration suppression control for applying braking torque based on the change speed difference.