Patents by Inventor Takayuki Imamura

Takayuki Imamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200331434
    Abstract: A wiper device including a wiper member that includes a wiper arm to which a wiper blade is coupled, a base end portion of the wiper arm being supported by a support section provided at a vehicle, and the wiper member being configured to of undergo displacement relative to the vehicle, a drive wheel that is rotatably supported by the wiper member at a position of the wiper member which is separated from the support section, and that rolls across a running face provided at the vehicle so as to displace the wiper member relative to the vehicle, and a motor that is supported by the wiper member so as to undergo displacement together with the wiper member, and that drives rotation of the drive wheel.
    Type: Application
    Filed: April 10, 2020
    Publication date: October 22, 2020
    Applicant: DENSO CORPORATION
    Inventor: Takayuki IMAMURA
  • Publication number: 20200046877
    Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.
    Type: Application
    Filed: October 22, 2019
    Publication date: February 13, 2020
    Applicants: TEIJIN LIMITED, Teijin Pharma Limited, KM BIOLOGICS CO., LTD.
    Inventors: Yukako KAGEYAMA, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Aklyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
  • Patent number: 10485894
    Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: November 26, 2019
    Assignees: TEIJIN LIMITED, Teijin Pharma Limited, KM BIOLOGICS CO., LTD.
    Inventors: Yukako Kageyama, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Akiyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
  • Publication number: 20190168718
    Abstract: The present disclosure provides a vehicle wiper-washer device including: a wiper motor causing to-and-fro wiping operation on a wiping surface by a wiper blade coupled to a wiper arm; a washer pump that feeds washer fluid under pressure to a jetting portion provided to at least one of the wiper blade or the wiper arm, to cause washer fluid to be jetted from the jetting portion toward the wiping surface on an outward movement direction side of the wiper blade during the to-and-fro wiping operation; and a control unit that, when a predetermined signal is detected, controls the wiper motor and the washer pump such that the to-and-fro wiping operation is performed, and such that washer fluid is jetted from the jetting portion toward the wiping surface on the outward movement direction side while a return path wiping operation of the to-and-fro wiping operation is being performed.
    Type: Application
    Filed: July 10, 2017
    Publication date: June 6, 2019
    Applicant: DENSO CORPORATION
    Inventors: Masaaki KIYAMA, Yasuhiro HARITA, Takayuki IMAMURA
  • Patent number: 9149557
    Abstract: A process for preparing a bioabsorbable sheet preparation holding thrombin is provided. A process for preparing a bioabsorbable sheet preparation holding thrombin which comprises immersing a bioabsorbable sheet consisting of polyglycolic acid in a thrombin solution containing thrombin as an active ingredient, glycerol as a softening agent, Tween 80 as a permeating agent, and optionally histidine and trehalose as a stabilizing agent followed by drying to hold thrombin on said bioabsorbable sheet, and a bioabsorbable sheet preparation holding thrombin prepared by said process.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: October 6, 2015
    Assignee: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
    Inventors: Ryoichi Kawamura, Takayuki Imamura, Hitomi Owaki
  • Publication number: 20150151020
    Abstract: A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.
    Type: Application
    Filed: May 13, 2013
    Publication date: June 4, 2015
    Applicants: TEIJIN LIMITED, TEIJIN PHARMA LIMITED, THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
    Inventors: Yukako Kageyama, Kentaro Fujinaga, Ayuko Yamaguchi, Yusuke Akiyama, Akitoshi Oono, Susumu Honda, Makoto Satake, Hiroaki Kaneko, Takayuki Imamura, Ryoichi Kawamura, Masaki Hirashima
  • Patent number: 8679783
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: March 25, 2014
    Assignee: The Chemo-Sero-Therapeutic Research Institute
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Patent number: 8293874
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Grant
    Filed: September 16, 2011
    Date of Patent: October 23, 2012
    Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Publication number: 20120231523
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Application
    Filed: February 24, 2012
    Publication date: September 13, 2012
    Applicant: JURIDICAL FDN THE CHEMO-SERO-THERAPEUTIC RES INST
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Patent number: 8173777
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Grant
    Filed: October 8, 2008
    Date of Patent: May 8, 2012
    Assignee: Juridical Foundation the Chemo-Sero-Therapeutic Research Institute
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Publication number: 20120039863
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Application
    Filed: September 16, 2011
    Publication date: February 16, 2012
    Applicant: JURIDICAL FDN THE CHEMO-SERO-THERAPEUTIC RES INST
    Inventors: Kenji SOEJIMA, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Patent number: 8043629
    Abstract: A safe and effective hemostatic is provided. The invention relates to a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient and a hemostatic comprising said bioabsorbable synthetic nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention may be prepared by a process which comprises the steps of immersing a bioabsorbable synthetic nonwoven fabric into a solution containing thrombin and of lyophilizing the obtained nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention allows for quicker and more effective hemostasis.
    Type: Grant
    Filed: November 16, 2007
    Date of Patent: October 25, 2011
    Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
    Inventors: Takanori Uchida, Noriko Shinya, Hiroshi Kaetsu, Takayuki Imamura, Chikateru Nozaki
  • Publication number: 20110038847
    Abstract: A process for preparing a bioabsorbable sheet preparation holding thrombin is provided. A process for preparing a bioabsorbable sheet preparation holding thrombin which comprises immersing a bioabsorbable sheet consisting of polyglycolic acid in a thrombin solution containing thrombin as an active ingredient, glycerol as a softening agent, Tween 80 as a permeating agent, and optionally histidine and trehalose as a stabilizing agent followed by drying to hold thrombin on said bioabsorbable sheet, and a bioabsorbable sheet preparation holding thrombin prepared by said process.
    Type: Application
    Filed: April 15, 2009
    Publication date: February 17, 2011
    Applicant: THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
    Inventors: Ryoichi Kawamura, Takayuki Imamura, Hitomi Owaki
  • Publication number: 20100285568
    Abstract: A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
    Type: Application
    Filed: October 8, 2008
    Publication date: November 11, 2010
    Applicant: JURIDICAL FDN THE CHEMO-SERO-THERAPEUTIC RES INST
    Inventors: Kenji Soejima, Takayuki Imamura, Ryoichi Kawamura, Hiroshi Nakatake, Arisa Maeyashiki, Hitomi Togo
  • Patent number: 7829306
    Abstract: A gene encoding a production amount-potentiating factor is introduced into an animal cell to transform the cell. Alternatively, a protein production gene and the gene encoding the production amount-potentiating factor are introduced into the animal cell to transform the cell. Herein, as the production amount potentiating factor, there is used a factor having caspase activity inhibiting activity and/or protein biosynthesis activity potentiating action, for example, baculovirus P35. Further, the animal cell is cultured by a culturing method under a condition that apoptosis is not induced, so that a protein is mass-produced.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: November 9, 2010
    Assignee: Juridical Foundation the Chemo-Sero-Therapeutic Research Institute
    Inventors: Reiko Matsuyama, Hiroaki Maeda, Hitomi Shirahama, Takayuki Imamura, Yasuharu Kamachi
  • Patent number: 7685670
    Abstract: An input disk, a clutch disk and wave washers are installed to an output shaft to form an output shaft assembly of a motor apparatus. The input disk is axially non-detachable from the output shaft and is rotatable about an axis of the output shaft. The input disk is driven by a drive force supplied from a motor main body of the motor apparatus. The clutch disk is supported by the output shaft in such a manner that the clutch disk is non-rotatable relative to the output shaft and is axially movable along the output shaft relative to the input disk. The wave washers apply a resistive force against axial movement of the clutch disk from a coupled state, at which the input disk is coupled with the clutch disk to rotate together.
    Type: Grant
    Filed: November 2, 2004
    Date of Patent: March 30, 2010
    Assignee: ASMO Co., Ltd.
    Inventors: Hideyuki Yagi, Takayuki Imamura
  • Patent number: 7568257
    Abstract: Initiation of coupling between an input disk and a clutch disk at a maximum rotational coupling force without making relative rotation between the input disk and the clutch disk is enabled only when the output shaft is placed in a single engageable point within a normal reciprocal angular range of the output shaft. When a load applied to the output shaft is equal to or greater than a predetermined value, the input disk and the clutch disk are decoupled from one another, so that the relative rotation is made between the input disk and the clutch disk.
    Type: Grant
    Filed: November 2, 2004
    Date of Patent: August 4, 2009
    Assignee: ASMO Co., Ltd.
    Inventors: Hideyuki Yagi, Takayuki Imamura
  • Publication number: 20090137001
    Abstract: The present invention provides for a process for preparing a recombinant human thrombin. A process for preparing a recombinant human thrombin which comprises: (1) obtaining a transfectant cell producing a human prothrombin by introducing an expression vector, wherein a gene fragment coding for a human prothrombin gene is incorporated, into an animal cell; (2) purifying a human prothrombin from the culture of the transfectant cell above by an anion exchanger; (3) converting the purified human prothrombin into a human thrombin by subjecting said human prothrombin to the action of ecarin; and (4) purifying the human thrombin from the solution after treatment with ecarin by an affinity method using benzamidine and a cation exchanger, and human thrombin obtained by said process, and a CHO cell that produces human prothrombin.
    Type: Application
    Filed: September 29, 2006
    Publication date: May 28, 2009
    Inventors: Tatsufumi Onchi, Yo Nakahara, Takayuki Imamura, Toshinobu Nouchi, Hiroshi Nakatake
  • Publication number: 20090099338
    Abstract: A gene encoding a production amount-potentiating factor is introduced into an animal cell to transform the cell. Alternatively, a protein production gene and the gene encoding the production amount-potentiating factor are introduced into the animal cell to transform the cell. Herein, as the production amount potentiating factor, there is used a factor having caspase activity inhibiting activity and/or protein biosynthesis activity potentiating action, for example, baculovirus P35. Further, the animal cell is cultured by a culturing method under a condition that apoptosis is not induced, so that a protein is mass-produced.
    Type: Application
    Filed: October 21, 2004
    Publication date: April 16, 2009
    Applicant: JURIDICAL FOUNDATION THE CHEMO-THERAPEUTIC RESEARC
    Inventors: Reiko Matsuyama, Hiroaki Maeda, Hitomi Shirahama, Takayuki Imamura, Yasuharu Kamachi
  • Publication number: 20080286347
    Abstract: A safe and effective hemostatic is provided. The invention relates to a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient and a hemostatic comprising said bioabsorbable synthetic nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention may be prepared by a process which comprises the steps of immersing a bioabsorbable synthetic nonwoven fabric into a solution containing thrombin and of lyophilizing the obtained nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention allows for quicker and more effective hemostasis.
    Type: Application
    Filed: November 16, 2007
    Publication date: November 20, 2008
    Applicant: JURIDICAL FOUNDATION THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE
    Inventors: Takanori UCHIDA, Noriko Shinya, Hiroshi Kaetsu, Takayuki Imamura, Chikateru Nozaki