Patents by Inventor Takeshi Kawarabayashi

Takeshi Kawarabayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transformed soybean plant which accumulates vaccine, and use thereof
    Patent number: 8937218
    Abstract: A transformed soybean plant having a gene encoding a modified seed storage protein introduced therein, obtained by inserting a gene encoding an Alzheimer's disease vaccine to a variable region(s) of a gene encoding a wild-type seed storage protein, is produced, and said vaccine is produced and accumulated in the seeds thereof.
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: January 20, 2015
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Masao Ishimoto, Mikio Shoji, Takeshi Kawarabayashi, Yasuko Utsumi
  • Vaccine composition for prophylaxis and/or therapy of Alzheimer's disease
    Patent number: 8912145
    Abstract: A vaccine composition for prophylaxis and/or therapy of Alzheimer's disease, which comprises a fusion protein prepared by inserting a single or tandemly repeated multiple copies of amyloid ? antigenic peptide having 5 to 15 continuous amino acid residues derived from the N-terminus of amyloid ? peptide into a wild type seed storage protein.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: December 16, 2014
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Yasushi Shimada, Atsushi Takahashi, Takeshi Kawarabayashi, Mikio Shoji
  • VACCINE COMPOSITION FOR PROPHYLAXIS AND/OR THERAPY OF ALZHEIMER'S DISEASE
    Publication number: 20120052086
    Abstract: A vaccine composition for prophylaxis and/or therapy of Alzheimer's disease, which comprises a fusion protein prepared by inserting a single or tandemly repeated multiple copies of amyloid ? antigenic peptide having 5 to 15 continuous amino acid residues derived from the N-terminus of amyloid ? peptide into a wild type seed storage protein.
    Type: Application
    Filed: November 7, 2011
    Publication date: March 1, 2012
    Applicant: Hokko Chemical Industry Co., Ltd.
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Yasushi Shimada, Atsushi Takahashi, Takeshi Kawarabayashi, Mikio Shoji
  • TRANSFORMED SOYBEAN PLANT WHICH ACCUMULATES VACCINE, AND USE THEREOF
    Publication number: 20110243975
    Abstract: A transformed soybean plant having a gene encoding a modified seed storage protein introduced therein, obtained by inserting a gene encoding an Alzheimer's disease vaccine to a variable region(s) of a gene encoding a wild-type seed storage protein, is produced, and said vaccine is produced and accumulated in the seeds thereof.
    Type: Application
    Filed: November 26, 2009
    Publication date: October 6, 2011
    Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Masao Ishimoto, Shigeru Utsumi, Yasuko Utsumi, Mikio Shoji, Takeshi Kawarabayashi
  • Transgenic mouse expressing an .beta.-Amyloid transgene
    Patent number: 6037521
    Abstract: The invention relates to an animal model of human Alzheimer's disease that is useful for determining the mechanism of the disease and for developing and testing potential therapeutic drugs. More particularly, the present invention relates to the creation of transgenic non-human mammalian animals having integrated into their genome an exogenous DNA construct that encodes a portion of a .beta.-amyloid precursor protein ("APP") and that is designed to overexpress in various types of animal tissues.
    Type: Grant
    Filed: November 14, 1994
    Date of Patent: March 14, 2000
    Assignee: Hoechst Japan Limited
    Inventors: Masahiro Sato, Takashi Kobayashi, Norihiro Tada, Mikio Shoji, Takeshi Kawarabayashi