Patents by Inventor Takeshi Kinsho

Takeshi Kinsho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240409480
    Abstract: The present invention relates to a process for preparing a haloalkyl alkoxymethyl ether compound of the following general formula (1?), wherein X1 represents a halogen atom, R1 represents a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group, and n represents an integer of 2 to 7, the process comprising the steps of converting a haloalkyl alkoxymethyl ether compound of the following general formula (1) into a nucleophilic reagent, (2n+2)-alkoxymethoxyalkyl compound, of the following general formula (2), wherein M1 represents Li, MgZ1, CuZ1, or CuLiZ1, Z1 represents a halogen atom or Z2, subsequently subjecting the nucleophilic reagent, (2n+2)-alkoxymethoxyalkyl compound (2), to a nucleophilic addition reaction with propylene oxide of the following formula (3), to obtain a hydroxyalkyl alkoxymethyl ether compound of the following general formula (4), and subjecting the hydroxyalkyl alkoxymethyl ether compound (4) to a halogenation reaction to obtain the aforesaid haloalkyl alkoxymethy
    Type: Application
    Filed: May 29, 2024
    Publication date: December 12, 2024
    Inventors: Yuki Miyake, Takeru Watanabe, Takeshi Kinsho, Ryo Komatsu
  • Publication number: 20240400484
    Abstract: The present invention relates to a process for preparing a haloalkyl alkoxymethyl ether compound (1B), wherein X1 represents a halogen atom, and R1 represents a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group, the process comprising the steps of converting a haloalkyl alkoxymethyl ether compound of the following general formula (1A), wherein X1 and R1 are as defined above, into a nucleophilic reagent, 4-alkoxymethoxy-1-methylbutyl, of the following general formula (2A), wherein M1A represents Li, MgZ1A, CuZ1A, or CuLiZ1A, Z1A represents a halogen atom or a 4-alkoxymethoxy-1-methylbutyl group, and R1 is as defined above, and subsequently subjecting the nucleophilic reagent, 4-alkoxymethoxy-1-methylbutyl (2A), to a nucleophilic addition reaction with propylene oxide of the following formula (3) to obtain 6-hydroxy-4-methylheptyl alkoxymethyl ether compound of the following general formula (4), wherein R1 is as defined above, and subjecting the 6-hydroxy-4-methylheptyl alkoxymethyl
    Type: Application
    Filed: May 29, 2024
    Publication date: December 5, 2024
    Inventors: Yuki Miyake, Takeru Watanabe, Takeshi Kinsho, Yusuke Nagae
  • Patent number: 12139454
    Abstract: The present invention provides a process for preparing a dimethylcyclobutane compound of the following general formula (1A), the process comprising reacting a dimethylcyclobutanone compound of the following general formula (2) with a phosphonic ester compound of the following general formula (3) to produce an unsaturated ester compound of the following general formula (4), having a dimethylcyclobutane ring, and subjecting the unsaturated ester compound (4), having a dimethylcyclobutane ring, to a reduction reaction to produce the dimethylcyclobutane compound (1A).
    Type: Grant
    Filed: June 7, 2022
    Date of Patent: November 12, 2024
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Naoki Ishibashi, Yusuke Nagae, Takeshi Kinsho
  • Publication number: 20240368056
    Abstract: The present invention relates to a 1-halo-7-methyltricosane compound of the following general formula (1), wherein X1 represents a halogen atom. The present invention relates also to a process for preparing a 17-methylalkane compound of the following general formula (4), wherein n represents an integer of 11 to 13, the process comprising the steps of converting the aforesaid 1-halo-7-methyltricosane compound (1) into a nucleophilic reagent, 7-methyltricosyl compound, of the following general formula (2), wherein M1 represents Li, MgZ1, CuZ1, or CuLiZ1, and Z1 represents a halogen atom or a 7-methyltricosyl group, subsequently subjecting the aforesaid nucleophilic reagent, 7-methyltricosyl compound (2), to a coupling reaction with an electrophilic alkyl reagent of the following general formula (3), wherein X2 represents a halogen atom or a p-toluenesulfonyloxy group, and n is as defined above, to form the aforesaid 17-methylalkane compound (4).
    Type: Application
    Filed: April 29, 2024
    Publication date: November 7, 2024
    Inventors: Yuki Miyake, Takeru Watanabe, Takeshi Kinsho
  • Publication number: 20240368061
    Abstract: The present invention relates to a 1-halo-2,6,14-trimethyloctadecane compound of the following general formula (1), wherein X1 represents a halogen atom. The present invention further relates to a process for preparing a 5,13,17-trimethylalkane compound of the following general formula (4), wherein n represents an integer of 14 to 18, the process comprising converting the aforesaid 1-halo-2,6,14-trimethyloctadecane compound (1) into a nucleophilic reagent, 2,6,14-trimethyloctadecyl, of the following general formula (2), wherein M1 represents Li or MgZ1, and Z1 represents a halogen atom or a 2,6,14-trimethyloctadecyl group, and subsequently subjecting the nucleophilic reagent, 2,6,14-trimethyloctadecyl compound (2), to a coupling reaction with an electrophilic alkyl reagent (3) of the following general formula (3), wherein X2 represents a halogen atom or a p-toluenesulfonyloxy group, and n is as defined above, to obtain the aforesaid 5,13,17-trimethylalkane compound (4).
    Type: Application
    Filed: April 29, 2024
    Publication date: November 7, 2024
    Inventors: Yuki Miyake, Yuma Sugawara, Takeru Watanabe, Takeshi Kinsho
  • Patent number: 12116328
    Abstract: The present invention provides a process for preparing an 11-halo-3-undecene compound (7) in which X1 represents a halogen atom, the process comprising a step of subjecting a nucleophilic reagent, 3-hexenyl compound (5): in which M2 represents Li or MgZ2, wherein Z2 represents a halogen atom or a 3-hexenyl group, to a coupling reaction with a 1-halo-5-halopentane compound (6) in which X3 and X4 may be same with or different from each other and represent a halogen atom, to produce the 11-halo-3-undecene compound (7).
    Type: Grant
    Filed: July 7, 2020
    Date of Patent: October 15, 2024
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Yuki Miyake, Takeshi Kinsho, Ryo Komatsu
  • Patent number: 12060323
    Abstract: The present invention relates to a 6-hydroxy-3-hexenyl alkoxymethyl ether compound of the following general formula (1): HOCH2CH2CH=CHCH2CH2OCH2OCH2R1 (1), R1 representing a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group; and also relates to a process for preparing a 3,13-octadecadien-1-ol compound of the following formula (6): CH3(CH2)3CH—CH(CH2)8CH?CHCH2CH2OH (6) from the 6-hydroxy-3-hexenyl alkoxymethyl ether compound (1).
    Type: Grant
    Filed: April 19, 2023
    Date of Patent: August 13, 2024
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Yuki Miyake, Takeshi Kinsho, Yusuke Nagae
  • Patent number: 11970432
    Abstract: The present invention provides a process for preparing 2-methyl-N-(2?-methylbutyl)butanamide of the following formula (1): the process comprising: subjecting an ?-arylethyl-2-methylbutylamine compound of the following general formula (2): wherein Ar represents a substituted or unsubstituted aryl group having 6 to 20 carbon atoms, to N-2-methylbutyrylation to form an N-?-arylethyl-2-methyl-N-(2?-methylbutyl)butanamide compound of the following general formula (3): wherein Ar is as defined above, and removing the ?-arylethyl group of the resulting compound (3) to form 2-methyl-N-(2?-methylbutyl)butanamide (1).
    Type: Grant
    Filed: February 28, 2023
    Date of Patent: April 30, 2024
    Assignee: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Takeshi Kinsho, Yusuke Nagae, Shogo Tsukaguchi, Yasuhiko Kutsuwada, Tatsuya Hojo, Takeru Watanabe
  • Patent number: 11958801
    Abstract: A process for process for preparing 6-isopropenyl-3-methyl-9-decenyl acetate of the following formula (3), wherein Ac represents an acetyl group, the process comprising steps of: preparing a nucleophilic reagent, 5-isopropenyl-2-methyl-8-nonenyl compound, of the following general formula (1): wherein M1 represents Li, MgZ1, ZnZ1, Cu, CuZ1, or CuLiZ1, wherein Z1 represents a halogen atom or a 5-isopropenyl-2-methyl-8-nonenyl group, from a 5-isopropenyl-2-methyl-8-nonenyl halide compound of the following general formula (4): wherein X1 represents a halogen atom; subjecting the nucleophilic reagent (1), 5-isopropenyl-2-methyl-8-nonenyl compound, to an addition reaction with at least one electrophilic reagent selected from the group consisting of formaldehyde, paraformaldehyde, and 1,3,5-trioxane, followed by a hydrolysis reaction to form 6-isopropenyl-3-methyl-9-decenol of the following formula (2); and acetylating 6-isopropenyl-3-methyl-9-decenol (2) to form 6-isopropenyl-3-methyl-9-decenyl acetate (3).
    Type: Grant
    Filed: January 13, 2023
    Date of Patent: April 16, 2024
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Akihiro Baba, Takeshi Kinsho, Yusuke Nagae
  • Publication number: 20240067595
    Abstract: Provided is a 3-acyloxymethyl-3-butenal acetal compound of General Formula (10): wherein R1 and R2, which may be the same or different, are each an alkyl group having 1 to 6 carbon atoms, or are bonded to each other to form a divalent alkylene group having 2 to 12 carbon atoms, and X1 is an acyloxy group having 1 to 6 carbon atoms.
    Type: Application
    Filed: September 21, 2023
    Publication date: February 29, 2024
    Inventors: Takeshi Kinsho, Akihiro Baba, Yusuke Nagae, Tomohiro Watanabe
  • Patent number: 11897842
    Abstract: A method for producing a 7-methyl-3-methylene-7-octenyl carboxylate compound (1), the method including the step of coupling a nucleophilic reagent of General Formula (8): wherein M is a cationic moiety, with an acetal compound of General Formula (9): wherein R1 and R2, which may be the same or different, are each an alkyl group having 1 to 6 carbon atoms, or are bonded to each other to form a divalent alkylene group having 2 to 12 carbon atoms, and X is a leaving group, to obtain the 7-methyl-3-methylene-7-octenal acetal compound.
    Type: Grant
    Filed: June 6, 2022
    Date of Patent: February 13, 2024
    Inventors: Takeshi Kinsho, Akihiro Baba, Yusuke Nagae, Tomohiro Watanabe
  • Publication number: 20240025837
    Abstract: A method for producing 7-methyl-3-methylene-7-octenal of Formula (2) is provided and includes a step of hydrolyzing a 7-methyl-3-methylene-7-octenal acetal compound of General Formula (1): wherein R1 and R2, which may be the same or different, are each analkyl group having 1 to 6 carbon atoms, or are bonded to each other to form a divalent alkylene group having 2 to 12 carbon atoms to obtain the 7-methyl-3-methylene-7-octenal (2).
    Type: Application
    Filed: September 22, 2023
    Publication date: January 25, 2024
    Inventors: Takeshi Kinsho, Akihiro Baba, Yusuke Nagae, Tomohiro Watanabe
  • Patent number: 11840511
    Abstract: The present invention relates to a process for preparing a (2-cyclopentenyl)acetate ester compound of general formula (2) as described herein, the process comprising: subjecting a haloacetaldehyde alkyl 2-cyclopentenyl acetal compound of general formula (1) as described herein to a dehydrohalogenation reaction in the presence of a base, followed by a rearrangement reaction to form the (2-cyclopentenyl)acetate ester compound of general formula (2). The present invention also relates to a process for preparing a (2-cyclopentenyl)acetic acid compound of general formula (3) as described herein, the process comprising hydrolyzing the (2-cyclopentenyl)acetate ester compound of general formula (2) to form the (2-cyclopentenyl)acetic acid compound of general formula (3). The present invention also relates to a haloacetaldehyde alkyl 2-cyclopentenyl acetal compound of general formula (1) as described herein.
    Type: Grant
    Filed: June 6, 2022
    Date of Patent: December 12, 2023
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Miyoshi Yamashita, Takeshi Kinsho
  • Patent number: 11807602
    Abstract: The present invention relates to a process for preparing a 3-isopropenyl-6-heptenal compound of the following formula (2): wherein R1 represents a hydrogen atom or a methyl group, the process comprising: subjecting a 3-isopropenyl-6-heptenoate ester compound of the following formula (1): wherein R1 is as defined above, and R2 represents a monovalent hydrocarbon group having 1 to 10 carbon atoms, to a reduction reaction with a reducing agent to form the 3-isopropenyl-6-heptenal compound (2).
    Type: Grant
    Filed: December 7, 2021
    Date of Patent: November 7, 2023
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Akihiro Baba, Takeshi Kinsho, Naoki Ishibashi, Yusuke Nagae
  • Patent number: 11795133
    Abstract: The present invention provides a process for preparing 6-isopropenyl-3-methyl-9-decenyl acetate (5): wherein Ac represents an acetyl group, the process comprising steps of: subjecting a 2-methyl-2,6-heptadiene compound (1) having a leaving group X at position 1: wherein X represents an acyloxy group having 1 to 10 carbon atoms including the carbon atom of the carbonyl group, an alkanesulfonyloxy group having 1 to 10 carbon atoms, an arenesulfonyloxy group having 6 to 20 carbon atoms, or a halogen atom, to a nucleophilic substitution reaction with a 3-methylpentyl nucleophilic reagent (2) having a protected hydroxyl group at position 5: wherein M represents Li, MgZ1, ZnZ1, Cu, CuZ1, or CuLiZ1, wherein Z1 represents a halogen atom or a CH2CH2CH(CH3)CH2CH2OR group, and R represents a protecting group for a hydroxyl group, to form a 6-isopropenyl-3-methyl-9-decene compound (3) having a protected hydroxyl group at position 1: wherein R is as defined above; subjecting the 6-isopropenyl-3-methyl-9-decene compound (3
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: October 24, 2023
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Akihiro Baba, Takeshi Kinsho
  • Patent number: 11780791
    Abstract: The present invention provides (6Z,9Z)-6,9-dodecadien-1-yne of the following formula (1). Further, the present invention provides a process for preparing (6Z,9Z)-6,9-dodecadien-1-yne (1): the process comprising reacting a (3Z,6Z)-10-halo-3,6-decadiene compound of the following general formula (2), wherein X represents a halogen atom with a metal acetylide of the following general formula (3), wherein M represents Na, Li, K, Ag, Cu (I), MgZ, CaZ, or Cu(II)Z, wherein Z represents a halogen atom or an ethinyl group to form (6Z,9Z)-6,9-dodecadien-1-yne (1).
    Type: Grant
    Filed: April 12, 2022
    Date of Patent: October 10, 2023
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Yuki Miyake, Takeshi Kinsho, Ryo Komatsu
  • Publication number: 20230312454
    Abstract: The present invention relates to a 6-hydroxy-3-hexenyl alkoxymethyl ether compound of the following general formula (1): HOCH2CH2CH=CHCH2CH2OCH2OCH2R1 (1), R1 representing a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group; and also relates to a process for preparing a 3,13-octadecadien-1-ol compound of the following formula (6): CH3(CH2)3CH=CH(CH2)8CH=CHCH2CH2OH (6) from the 6-hydroxy-3-hexenyl alkoxymethyl ether compound (1).
    Type: Application
    Filed: April 19, 2023
    Publication date: October 5, 2023
    Inventors: Yuki Miyake, Takeshi Kinsho, Yusuke Nagae
  • Patent number: 11767282
    Abstract: There are provided a composition which has a larger attracted number than (9Z)-9,13-tetradecadien-11-ynal alone; and others. More specifically, there are provided a composition bioactive to Stenoma catenifer (STENCA), the composition including (9Z)-9,13-tetradecadien-11-ynal and (9E)-9,13-tetradecadien-11-ynal; a sustained release preparation for controlling STENCA, the preparation including the composition and a carrier or container for sustainedly releasing the (9Z)-9,13-tetradecadien-11-ynal and the (9E)-9,13-tetradecadien-11-ynal; and a method for controlling STENCA, the method including a step of installing the sustained release preparation in a field to release the (9Z)-9,13-tetradecadien-11-ynal and the (9E)-9,13-tetradecadien-11-ynal into the field.
    Type: Grant
    Filed: June 24, 2022
    Date of Patent: September 26, 2023
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Yuki Miyake, Tatsuya Fujii, Yasuhiko Kutsuwada, Takeru Watanabe, Takeshi Kinsho
  • Patent number: 11746078
    Abstract: The present invention relates to a process for preparing a (1S,2R)-(2-hydroxy-3,5,5-trimethyl-3-cyclopentenyl)methyl carboxylate compound of the following general formula (S,R)-(2), wherein R1 represents a monovalent hydrocarbon group having 1 to 6 carbon atoms, and a bold wedged bond represents the absolute configuration, and a (1R,2S)-(2-acetoxy-3,5,5-trimethyl-3-cyclopentenyl)methyl carboxylate compound of the following general formula (R,S)-(3), wherein R1 is as defined above, a hashed wedged bond represents the absolute configuration, and Ac represents an acetyl group, the process comprising: subjecting a (1RS,2SR)-(2-hydroxy-3,5,5-trimethyl-3-cyclopentenyl)methyl carboxylate compound of the following general formula (RS,SR)-(2), wherein R1 is as defined above, and a hashed unwedged bond represents a relative configuration, to a kinetic resolution reaction with a lipase in the presence of vinyl acetate to obtain the (1S,2R)-(2-hydroxy-3,5,5-trimethyl-3-cyclopentenyl)methyl carboxylate compound ((S,R)-(2)
    Type: Grant
    Filed: January 21, 2022
    Date of Patent: September 5, 2023
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Tomohiro Watanabe, Takeshi Kinsho, Takeru Watanabe, Miyoshi Yamashita, Yusuke Nagae
  • Patent number: 11731930
    Abstract: The present invention provides a process for preparing a (1,2-dimethyl-3-methylenecyclopentyl)acetate compound of the following general formula (3), wherein R represents a linear or branched alkyl group having 1 to 4 carbon atoms, the process comprising subjecting a haloacetaldehyde alkyl 2,3-dimethyl-2-cyclopentenyl acetal compound of the following general formula (1), wherein R is as defined above, and Y represents a halogen atom, to a dehydrohalogenation reaction in the presence of a base, followed by a rearrangement reaction to obtain a (1,2-dimethyl-2-cyclopentenyl)acetate compound of the following general formula (2), wherein R is as defined above, and subjecting the (1,2-dimethyl-2-cyclopentenyl)acetate compound (2) to an epoxidation reaction, followed by an isomerization reaction and then a methylenation reaction to obtain the (1,2-dimethyl-3-methylenecyclopentyl)acetate compound of the following general formula (3).
    Type: Grant
    Filed: June 6, 2022
    Date of Patent: August 22, 2023
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Miyoshi Yamashita, Takeru Watanabe, Takeshi Kinsho