Patents by Inventor Takumi Fukumoto
Takumi Fukumoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230119326Abstract: An embodiment of the present invention is to provide a bioabsorbable medical material having adhesiveness to a biological tissue and improved degradability. A bioabsorbable medical material according to an embodiment of the present invention contains a crosslinked polymer material forming a specific shape, and a disintegration delaying material retained by the crosslinked polymer material. The crosslinked polymer material has degradability in water, the degradability being suppressed in the presence of an acid. The disintegration delaying material releases 0.5 mol%/day or greater of an acid until the seventh day upon contact with water at 37° C.Type: ApplicationFiled: March 31, 2021Publication date: April 20, 2023Applicants: Kureha Corporation, NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITYInventors: Kazuhisa TAKATSUJI, Ayako FUJIEDA, Sumie GOTO, Yoshiki MACHI, Junya HIRATA, Hironao SHIMADA, Rieko HIRATA, Fujio SEKINE, Yusuke YAMASHITA, Takehiro SATO, Mie AKANUMA, Takumi FUKUMOTO
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Patent number: 11617868Abstract: The balloon catheter of the present invention is provided with a balloon base at a front end of a tubular catheter body having a predetermined length. The balloon base includes a cylindrical base having a larger diameter than an outer diameter of the catheter body, and a lumen having substantially the same diameter as the outer diameter of the catheter body is formed on the base over an entire length with both ends opened. A central axis of the lumen is inclined at a predetermined angle with respect to a central axis of the base concentric with a central axis of the catheter body, and an outer peripheral surface is formed in parallel with the central axis of the base. The balloon is provided on the outer peripheral surface of the parallel base to obliquely inflate with respect to the central axis of the catheter body during inflation.Type: GrantFiled: March 30, 2016Date of Patent: April 4, 2023Assignees: NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY, FUJI SYSTEMS CORPORATIONInventors: Eisei Gu, Takumi Fukumoto, Fumikazu Watanabe, Akihiro Asai
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Publication number: 20210317459Abstract: The purpose of the present invention is to provide an antisense oligonucleotide that targets an ARL4C molecule and exerts an antitumor effect in vivo, and a nucleic acid drug using the antisense oligonucleotide. An antisense oligonucleotide that has a base sequence consisting of at least 10 consecutive bases contained in the base sequence represented by SEQ ID NO: 1. This antisense oligonucleotide targets an ARL4C molecule and thus can inhibit the expression of ARL4C in a tumor cell in vitro and suppress the migration and proliferation thereof. When systemically administered, moreover, the antisense oligonucleotide can exert an excellent antitumor effect in vivo too.Type: ApplicationFiled: September 4, 2019Publication date: October 14, 2021Inventors: Akira KIKUCHI, Shinji MATSUMOTO, Satoshi OBIKA, Yuya KASAHARA, Takumi FUKUMOTO
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Patent number: 10994056Abstract: A device for fixing biological soft tissue is endowed with strength and deformation performance for being used as a device for coupling biological soft tissue that has been cut or separated due to an incision or the like during a surgical procedure, and is completely degraded in vivo and discharged after adhesion of the soft tissue or after healing of the incision tissue. The device is composed of a ternary Mg alloy material of Mg—Ca—Zn. In the Mg alloy material, the Ca and Zn are contained within the solid-solubility limit with respect to the Mg. The remainder is composed of Mg and unavoidable impurities. The Zn content is 0.5 at % or less. The Ca and Zn content has a relationship of Ca:Zn=1:x (where x is 1 to 3) by atom ratio. The crystal grain structure is equiaxed, the crystal grain size according to linear intercept being 30 to 250 ?m.Type: GrantFiled: September 9, 2015Date of Patent: May 4, 2021Assignee: NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITYInventors: Toshiji Mukai, Naoko Ikeo, Eisei Gu, Takumi Fukumoto, Hikaru Yabuuchi
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Patent number: 10525281Abstract: Provided is a spacer for ionizing radiation therapy, which can be easily disposed in a living body, does not require abdominal surgery for removing the disposed spacer after radiation therapy, and can effectively separate a tissue to be treated from other tissues. The spacer for ionizing radiation therapy includes a fiber assembly obtained by three-dimensionally entangling a fibrous material formed of a biocompatible synthetic polymeric material. Specifically, the spacer has a thickness of 1 mm to 100 mm.Type: GrantFiled: October 28, 2010Date of Patent: January 7, 2020Assignees: National University Corporation Kobe University, Kanai Juyo Kogyo Co., LTD., Alfresa Pharma CorporationInventors: Takumi Fukumoto, Tsutomu Obata, Yoshitaka Tagami, Eiichi Uemura, Michiko Manabe
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Publication number: 20190366058Abstract: The balloon catheter of the present invention is provided with a balloon base at a front end of a tubular catheter body having a predetermined length. The balloon base includes a cylindrical base having a larger diameter than an outer diameter of the catheter body, and a lumen having substantially the same diameter as the outer diameter of the catheter body is formed on the base over an entire length with both ends opened. A central axis of the lumen is inclined at a predetermined angle with respect to a central axis of the base concentric with a central axis of the catheter body, and an outer peripheral surface is formed in parallel with the central axis of the base. The balloon is provided on the outer peripheral surface of the parallel base to obliquely inflate with respect to the central axis of the catheter body during inflation.Type: ApplicationFiled: March 30, 2016Publication date: December 5, 2019Applicants: NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY, FUJI SYSTEMS CORPORATIONInventors: Eisei GU, Takumi FUKUMOTO, Fumikazu WATANABE, Akihiro ASAI
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Publication number: 20190232086Abstract: Disclosed is a spacer for radiotherapy that can be easily compressed into a reduced thickness, and has a high capacity to reconstitute itself from a compressed state back to its initial thickness after removal of external force. The spacer for radiotherapy is a flexible structure having front and back main faces and thickness therebetween, and composed of strands of biocompatible and biodegradable synthetic fibers, wherein the spacer consists of (a) a pair of main face portions opposing each other with a gap therebetween and respectively defining the main faces of the structure, and (b) a linker portion linking between the pair of main face portions, (c) wherein the main face portions comprise a knitted-fabric structure or a weave structure made of the strands, and (d) wherein the linker portion is composed as a collection of linker strands formed of the said strands and respectively extending in the thickness direction of the spacer and linking the pair of main face portions with each other.Type: ApplicationFiled: September 14, 2017Publication date: August 1, 2019Inventors: Ryohei SASAKI, Takumi FUKUMOTO, Sachiko INUBUSHI, Tsutomu OBATA, Yoshitaka TAGAMI
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Publication number: 20170258968Abstract: A device for fixing biological soft tissue is endowed with strength and deformation performance for being used as a device for coupling biological soft tissue that has been cut or separated due to an incision or the like during a surgical procedure, and is completely degraded in vivo and discharged after adhesion of the soft tissue or after healing of the incision tissue. The device is composed of a ternary Mg alloy material of Mg—Ca—Zn. In the Mg alloy material, the Ca and Zn are contained within the solid-solubility limit with respect to the Mg. The remainder is composed of Mg and unavoidable impurities. The Zn content is 0.5 at % or less. The Ca and Zn content has a relationship of Ca:Zn=1:x (where x is 1 to 3) by atom ratio. The crystal grain structure is equiaxed, the crystal grain size according to linear intercept being 30 to 250 ?m.Type: ApplicationFiled: September 9, 2015Publication date: September 14, 2017Inventors: Toshiji MUKAI, Naoko IKEO, Eisei GU, Takumi FUKUMOTO, Hikaru YABUUCHI
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Publication number: 20160361565Abstract: A radiotherapy spacer is disclosed that has both flexibility for allowing it to gently cover the organs of various shapes along their surfaces and pressure resistance for preventing itself from being crushed under the pressure between organs and thus enabling it to retain its own shape and continuously ensure the therapeutic space. The spacer comprises a fiber assembly formed of entangled biocompatible fibers, which may be bioabsorbable, such as nonwoven fabric, and is characterized in that the density of the fiber assembly is 0.05 g/cm3 to 0.2 g/cm3.Type: ApplicationFiled: December 24, 2014Publication date: December 15, 2016Inventors: Takumi FUKUMOTO, Ryohei SASAKI, Tsutomu MORIHARA, Yoshio SASAI, Yoshihisa FURUTA, Tsutomu OBATA, Yoshitaka TAGAMI
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Publication number: 20120271093Abstract: Provided is a spacer for ionizing radiation therapy, which can be easily disposed in a living body, does not require abdominal surgery for removing the disposed spacer after radiation therapy, and can effectively separate a tissue to be treated from other tissues. The spacer for ionizing radiation therapy includes a fiber assembly obtained by three-dimensionally entangling a fibrous material formed of a biocompatible synthetic polymeric material. Specifically, the spacer has a thickness of 1 mm to 100 mm.Type: ApplicationFiled: October 28, 2010Publication date: October 25, 2012Applicants: NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY, ALFRESA PHARMA CORPORATION, KANAI JUYO KOGYO CO., LTD.Inventors: Takumi Fukumoto, Tsutomu Obata, Yoshitaka Tagami, Eiichi Uemura, Michiko Manabe