Patents by Inventor Tammie Benzinger

Tammie Benzinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for multi-modality quantification of neuroinflammation in central nervous system diseases
    Patent number: 11672468
    Abstract: Methods and systems for diagnosing a condition of a central nervous system are provided. A method includes providing a DBSI-MRI data set obtained from the central nervous system of the subject, and transforming the DBSI-MRI data set to obtain at least one DBSI biomarker value. The method further includes comparing each DBSI biomarker value to at least one corresponding threshold value from a diagnostic database to obtain a relation between each DBSI biomarker value and the at least one corresponding threshold value, and diagnosing the condition according to at least one diagnostic rule, wherein each diagnostic rule defines a candidate condition in terms of the relations between the at least one DBSI biomarker value and the at least one corresponding threshold value.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: June 13, 2023
    Assignee: Washington University
    Inventors: Yong Wang, Qing Wang, Tammie Benzinger
  • QUANTITATIVE DIFFERENTIATION OF TUMOR HETEROGENEITY USING DIFFUSION MR IMAGING DATA
    Publication number: 20210177348
    Abstract: Provided herein are methods for imaging and diagnosing at least one disorder in a patient utilizing diffusion basis spectrum imaging MRI with extended isotropic spectrum (DBSI-EIS). The methods may be used as a tool to image and diagnose heterogeneities within tumors. As a result, different tumor types can be detected, distinguished from one another, and individually quantified without the need to inject exogenous contrast agents.
    Type: Application
    Filed: August 30, 2017
    Publication date: June 17, 2021
    Applicant: WASHINGTON UNIVERSITY
    Inventors: Yong Wang, Gloria Guzman, Qing Wang, Tammie Benzinger
  • SYSTEM AND METHOD FOR MULTI-MODALITY QUANTIFICATION OF NEUROINFLAMMATION IN CENTRAL NERVOUS SYSTEM DISEASES
    Publication number: 20200221991
    Abstract: Methods and systems for diagnosing a condition of a central nervous system are provided. A method includes providing a DBSI-MRI data set obtained from the central nervous system of the subject, and transforming the DBSI-MRI data set to obtain at least one DBSI biomarker value. The method further includes comparing each DBSI biomarker value to at least one corresponding threshold value from a diagnostic database to obtain a relation between each DBSI biomarker value and the at least one corresponding threshold value, and diagnosing the condition according to at least one diagnostic rule, wherein each diagnostic rule defines a candidate condition in terms of the relations between the at least one DBSI biomarker value and the at least one corresponding threshold value.
    Type: Application
    Filed: April 28, 2017
    Publication date: July 16, 2020
    Applicant: Washington University
    Inventors: Yong Wang, Qing Wang, Tammie Benzinger
  • QUANTITATIVE DIFFERENTIATION OF TUMOR HETEROGENEITY USING DIFFUSION MR IMAGING DATA
    Publication number: 20190223789
    Abstract: Provided herein are methods for imaging and diagnosing at least one disorder in a patient utilizing diffusion basis spectrum imaging MRI with extended isotropic spectrum (DBSI-EIS). The methods may be used as a tool to image and diagnose heterogeneities within tumors. As a result, different tumor types can be detected, distinguished from one another, and individually quantified without the need to inject exogenous contrast agents.
    Type: Application
    Filed: August 30, 2017
    Publication date: July 25, 2019
    Applicant: WASHINGTON UNIVERSITY
    Inventors: Yong Wang, Gloria Guzman, Qing Wang, Tammie Benzinger
  • SYSTEM AND METHOD FOR MULTI-MODALITY QUANTIFICATION OF NEUROINFLAMMATION IN CENTRAL NERVOUS SYSTEM DISEASES
    Publication number: 20190150822
    Abstract: Methods and systems for diagnosing a condition of a central nervous system are provided. A method includes providing a DBSI-MRI data set obtained from the central nervous system of the subject, and transforming the DBSI-MRI data set to obtain at least one DBSI biomarker value. The method further includes comparing each DBSI biomarker value to at least one corresponding threshold value from a diagnostic database to obtain a relation between each DBSI biomarker value and the at least one corresponding threshold value, and diagnosing the condition according to at least one diagnostic rule, wherein each diagnostic rule defines a candidate condition in terms of the relations between the at least one DBSI biomarker value and the at least one corresponding threshold value.
    Type: Application
    Filed: April 28, 2017
    Publication date: May 23, 2019
    Applicant: Washington University
    Inventors: Yong Wang, Qing Wang, Tammie Benzinger