Patents by Inventor Tan-chi Fan

Tan-chi Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180037909
    Abstract: The present invention relates to modified cancer cell lines, wherein the ST3Gal1 glycosyltransferase expression is reduced or inhibited. The use of the modified cancer cell lines with suppressed ST3Gal1 glycosyltransferase to screen a potential cancer therapeutic is provided. The suppression of ST3Gal1 glycosyltransferase expression, with or without an anti-cancer agent is also provided to inhibit the growth of cancer cells in a subject.
    Type: Application
    Filed: August 2, 2017
    Publication date: February 8, 2018
    Inventors: Alice L. Yu, Wen-Der Lin, Jung-Tung Hung, Tan-Chi Fan
  • Patent number: 8399416
    Abstract: The present invention is for an isolated peptide consisting of the amino acid sequence of SEQ ID NO: 9 and using the peptide for treating asthma by reducing cytotoxicity of eosinophil derived toxins in bronchial epithelial cells of the subject suffers from asthma. The method comprises preparing a pharmaceutical composition having the peptide of SEQ ID NO: 9 and administering an effective amount of the composition to the subject.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: March 19, 2013
    Assignee: National Tsing Hua University
    Inventors: Margaret Dah-Tsyr Chang, Tan-chi Fan, Shu-Chuan Lin
  • Publication number: 20120214730
    Abstract: The present invention is for an isolated peptide consisting of the amino acid sequence of SEQ ID NO: 9 and using the peptide for treating asthma by reducing cytotoxicity of eosinophil derived toxins in bronchial epithelial cells of the subject suffers from asthma. The method comprises preparing a pharmaceutical composition having the peptide of SEQ ID NO: 9 and administering an effective amount of the composition to the subject.
    Type: Application
    Filed: February 27, 2012
    Publication date: August 23, 2012
    Applicant: NATIONAL TSING HUA UNIVERSITY
    Inventors: Margaret Dah-Tsyr Chang, Tan-chi Fan, Shu-Chuan Lin
  • Publication number: 20100016239
    Abstract: A method for reducing cytotoxicity of eosinophil derived toxins comprising administering to a subject an effective amount of heparin, heparan sulfate, a potent heparanase inhibitor or a polypeptide which has sequence as follows: BZBXBX, XBBBXXBX, XBBXBX, BBXXBBBXXBB, BXBBXB, XBBBXXBBBXXBBX, or TXXBXXTBXXXTBB, wherein X represents any amino acid, Z represents an aromatic amino acid, and B represents a basic amino acid and T represents a turn.
    Type: Application
    Filed: August 21, 2009
    Publication date: January 21, 2010
    Applicant: NATIONAL TSING HUA UNIVERSITY
    Inventors: Margaret Dah-Tsyr Chang, Tan-chi Fan, Shu-Chuan Lin
  • Patent number: 7595374
    Abstract: A method for reducing cytotoxicity of eosinophil derived toxins comprising administering to a subject an effective amount of heparin, heparan sulfate, a potent heparanase inhibitor or a polypeptide which has sequence as follows: BZBXBX, XBBBXXBX, XBBXBX, BBXXBBBXXBB, BXBBXB, XBBBXXBBBXXBBX, or TXXBXXTBXXXTBB, wherein X represents any amino acid, Z represents an aromatic amino acid, and B represents a basic amino acid and T represents a turn.
    Type: Grant
    Filed: May 21, 2008
    Date of Patent: September 29, 2009
    Assignee: National Tsing Hua University
    Inventors: Margaret Dah-Tsyr Chang, Tan-chi Fan, Shu-Chuan Lin