Patents by Inventor Tania N. Gonzalez

Tania N. Gonzalez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Humanized anti-IL-8 monoclonal antibodies
    Patent number: 6133426
    Abstract: Humanized anti-IL-8 monoclonal antibodies and variants thereof are described for use in diagnostic applications and in the treatment of inflammatory disorders. Also described is a conjugate formed by an antibody fragment covalently attached to a non-proteinaceous polymer, wherein the apparent size of the conjugate is at least about 500 kD. The conjugate exhibits substantially improved half-life, mean residence time, and/or clearance rate in circulation as compared to the underivatized parental antibody fragment.
    Type: Grant
    Filed: February 20, 1998
    Date of Patent: October 17, 2000
    Assignee: Genentech, Inc.
    Inventors: Tania N. Gonzalez, Steven R. Leong, Leonard G. Presta
  • Humanized anti-IL-8 monoclonal antibodies
    Patent number: 6117980
    Abstract: Humanized anti-IL-8 monoclonal antibodies and variants thereof are described for use in diagnostic applications and in the treatment of inflammatory disorders.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: September 12, 2000
    Assignee: Genentech, Inc.
    Inventors: Tania N. Gonzalez, Steven R. Leong, Leonard G. Presta
  • Nucleic acids encoding humanized anti-IL-8 monoclonal antibodies
    Patent number: 6025158
    Abstract: Humanized anti-IL-8 monoclonal antibodies and variants thereof are described for use in diagnostic applications and in the treatment of inflammatory disorders. Also described is a conjugate formed by an antibody fragment covalently attached to a non-proteinaceous polymer, wherein the apparent size of the conjugate is at least about 500 kD. The conjugate exhibits substantially improved half-life, mean residence time, and/or clearance rate in circulation as compared to the underivatized parental antibody fragment.
    Type: Grant
    Filed: February 20, 1998
    Date of Patent: February 15, 2000
    Assignee: Genentech, Inc.
    Inventors: Tania N. Gonzalez, Steven R. Leong, Leonard G. Presta